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Mikako Warren, MD

Associate Professor of Clinical Pathology

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Email [email protected]
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Publications

  • Spatial Profiling Identifies Tumor-Associated Stroma Enrichment and MIF as Potential Immunotherapy Targets in Primary Ewing Sarcomas. Clin Cancer Res. 2025 Dec 01; 31(23):5051-5069.. View in PubMed
  • Lipidomic Analysis of Esophageal Epithelia Reveals a Distinctive Sphingolipid Profile in Eosinophilic Esophagitis. Allergy. 2025 Oct; 80(10):2849-2860.. View in PubMed
  • Tumor-associated stroma shapes the spatial tumor immune microenvironment of primary Ewing sarcomas. bioRxiv. 2025 Feb 06.. View in PubMed
  • Histologic and ultrastructural study of intracranial Gaucheroma causing deafness in a patient with Gaucher disease type 3: Effects of substrate reduction therapy. Mol Genet Metab Rep. 2024 Sep; 40:101106.. View in PubMed
  • Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors. Transl Pediatr. 2024 Apr 30; 13(4):624-633.. View in PubMed
  • Pediatric Sertoli-Leydig Cell Tumors of the Ovary: An Integrated Study of Clinicopathological Features, Pan-cancer-Targeted Next-generation Sequencing and Chromosomal Microarray Analysis From a Single Institution. Am J Surg Pathol. 2024 Feb 01; 48(2):194-203.. View in PubMed
  • Comparative Clinicopathologic and Genomic Analysis of Hepatocellular Neoplasm, Not Otherwise Specified, and Hepatoblastoma. Mod Pathol. 2024 Feb; 37(2):100385.. View in PubMed
  • Lysophosphatidic acid receptor 1 antagonist (EPGN2154) causes regression of NASH in preclinical NASH models. Hepatol Commun. 2023 12 01; 7(12).. View in PubMed
  • Current Utilization of Electron Microscopy in the Pediatric Pathology Setting: A Survey by the SPP Practice Committee. Pediatr Dev Pathol. 2023 Jul-Aug; 26(4):411-422.. View in PubMed
  • Chromosome 6p amplification detected in blood cell-free DNA in advanced intraocular retinoblastoma. Ophthalmic Genet. 2022 12; 43(6):866-870.. View in PubMed
  • In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish. J Cell Biol. 2022 11 07; 221(11).. View in PubMed
  • Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis. Nat Genet. 2022 08; 54(8):1214-1226.. View in PubMed
  • Primary Adrenal Malignant Rhabdoid Tumor in a 14-Year-Old Female: A Case Report and Literature Review. Int J Surg Pathol. 2022 Apr; 30(2):172-176.. View in PubMed
  • Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth. Elife. 2022 03 14; 11.. View in PubMed
  • Large Mesenteric Gaucheroma Responds to Substrate Reduction Therapy: A New Management of Gaucheromas. J Pediatr Genet. 2022 Mar; 11(1):47-50.. View in PubMed
  • PLAG1 Immunohistochemical Staining Is a Surrogate Marker for PLAG1 Fusions in Lipoblastomas. Pediatr Dev Pathol. 2022 Mar-Apr; 25(2):134-140.. View in PubMed
  • Kaposiform hemangioendothelioma of the bone in children and adolescents. Pediatr Blood Cancer. 2022 01; 69(1):e29392.. View in PubMed
  • Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection. Front Immunol. 2022; 13:831103.. View in PubMed
  • Mycophenolate Mofetil Hepatotoxicity Associated With Mitochondrial Abnormality in Liver Transplant Recipients and Mice. J Pediatr Gastroenterol Nutr. 2021 10 01; 73(4):463-470.. View in PubMed
  • Clinicopathologic Characteristics of Late Acute Antibody-mediated Rejection in Pediatric Liver Transplantation. Transplantation. 2021 09 01; 105(9):2045-2053.. View in PubMed
  • Microvillus inclusion disease with novel MYO5B pathogenic variants. Histopathology. 2021 07; 79(1):119-121.. View in PubMed
  • Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery. Endocrinology. 2021 04 01; 162(4).. View in PubMed
  • Bronchiectasis and Bronchiolectasis With Severe Herniating Pattern Associated With STAT1 Gain-of-Function Mutation: Detailed Clinicopathological Findings. Pediatr Dev Pathol. 2021 Mar-Apr; 24(2):131-136.. View in PubMed
  • PD-L1 expression in angiomatoid fibrous histiocytoma. Sci Rep. 2021 01 26; 11(1):2183.. View in PubMed
  • Phox2b Immunohistochemical Staining in Detecting Enteric Neural Crest Cells in Hirschsprung Disease. Pediatr Dev Pathol. 2021 Jan-Feb; 24(1):19-26.. View in PubMed
  • Noncongenital Pediatric Mature Teratoma of the Mandible. JAMA Otolaryngol Head Neck Surg. 2020 11 01; 146(11):1085-1086.. View in PubMed
  • Successful Induction Treatment With Rituximab of Isolated Pauci-Immune Pulmonary Capillaritis Presenting as Diffuse Alveolar Hemorrhage in a Pediatric Patient. Chest. 2020 11; 158(5):e225-e227.. View in PubMed
  • Persistent Toe-Walking in a Developmentally Normal 7-year-old Girl. Pediatr Rev. 2020 Oct; 41(Suppl 1):S3-S5.. View in PubMed
  • Association of a de novo nonsense mutation of the TRIM8 gene with childhood-onset focal segmental glomerulosclerosis. Pediatr Nephrol. 2020 06; 35(6):1129-1132.. View in PubMed
  • Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. Sci Rep. 2020 04 21; 10(1):6689.. View in PubMed
  • Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab. Blood. 2020 03 26; 135(13):1049-1057.. View in PubMed
  • Reduction of large soft-tissue Gaucheromas with substrate reduction therapy. J Inherit Metab Dis. 2020 03; 43(2):375-376.. View in PubMed
  • Use of electron microscopy when screening liver biopsies from neonates and infants: experience from a single tertiary children’s hospital (1991-2017). Ultrastruct Pathol. 2020 Jan 02; 44(1):32-41.. View in PubMed
  • Expanding the spectrum of dicer1-associated sarcomas. Mod Pathol. 2020 01; 33(1):164-174.. View in PubMed
  • Severe Late-Onset Acute Cellular Rejection in a Pediatric Patient With Isolated Small Intestinal Transplant Rescued With Aggressive Immunosuppressive Approach: A Case Report. Transplant Proc. 2019 Nov; 51(9):3181-3185.. View in PubMed
  • NTRK-rearranged mesenchymal tumour in a 3-year-old female: a diagnostic quandary. Histopathology. 2019 11; 75(5):772-775.. View in PubMed
  • Rare MYC-amplified Neuroblastoma With Large Cell Histology. Pediatr Dev Pathol. 2018 Sep-Oct; 21(5):461-466.. View in PubMed
  • Cytologic and Ultrastructural Findings of Bronchoalveolar Lavage in Patients With Chronic Granulomatous Disease. Pediatr Dev Pathol. 2018 Jul-Aug; 21(4):347-354.. View in PubMed
  • Histologic and ultrastructural features in early and advanced phases of Zellweger spectrum disorder (infantile Refsum disease). Ultrastruct Pathol. 2018 May-Jun; 42(3):220-227.. View in PubMed
  • Utility of Phox2b immunohistochemical stain in neural crest tumours and non-neural crest tumours in paediatric patients. Histopathology. 2018 Mar; 72(4):685-696.. View in PubMed
  • A Complete Histologic Approach to Gastrointestinal Biopsy From Hematopoietic Stem Cell Transplant Patients With Evidence of Transplant-Associated Gastrointestinal Thrombotic Microangiopathy. Arch Pathol Lab Med. 2017 Nov; 141(11):1558-1566.. View in PubMed
  • Gene fusions PAFAH1B1-USP6 and RUNX2-USP6 in aneurysmal bone cysts identified by next generation sequencing. Cancer Genet. 2017 04; 212-213:13-18.. View in PubMed
  • Importance of Phox2B Immunohistochemical Stain for Detecting Metastatic Neuroblastoma Cells in Bone Marrow Specimens. Pediatr Dev Pathol. 2016 May-Jun; 19(3):254-5.. View in PubMed
  • Calretinin-Immunoreactive Hypoinnervation in Down Syndrome (DS): Report of an Infant with Very Short-Segment Hirschsprung Disease and Comparison to Biopsy Findings in 20 Normal Infants and 11 Infants with DS and Chronic Constipation. Pediatr Dev Pathol. 2016 Mar-Apr; 19(2):87-93.. View in PubMed
  • Undifferentiated myxoid lipoblastoma with PLAG1-HAS2 fusion in an infant; morphologically mimicking primitive myxoid mesenchymal tumor of infancy (PMMTI)–diagnostic importance of cytogenetic and molecular testing and literature review. Cancer Genet. 2016 Jan-Feb; 209(1-2):21-9.. View in PubMed
  • Histologic Features of Intestinal Thrombotic Microangiopathy in Pediatric and Young Adult Patients after Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2015 Nov; 21(11):1994-2001.. View in PubMed
  • Molecular characterization of epithelioid haemangioendotheliomas identifies novel WWTR1-CAMTA1 fusion variants. Histopathology. 2015 Nov; 67(5):699-708.. View in PubMed
  • Integrated multimodal genetic testing of Ewing sarcoma–a single-institution experience. Hum Pathol. 2013 Oct; 44(10):2010-9.. View in PubMed
  • Pericardial effusion and cardiac tamponade in neonates: sudden unexpected death associated with total parenteral nutrition via central venous catheterization. Ann Clin Lab Sci. 2013; 43(2):163-71.. View in PubMed
  • Clinical impact of change of FLT3 mutation status in acute myeloid leukemia patients. Mod Pathol. 2012 Oct; 25(10):1405-12.. View in PubMed
  • Two cases of primary yolk sac tumor of the liver in childhood: case reports and literature review. Pediatr Dev Pathol. 2009 Sep-Oct; 12(5):410-6.. View in PubMed

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