Christian J. Hochstim, MD, PhD

Christian Hochstim, MD, completed a fellowship in pediatric otolaryngology at Stanford with broad training in a range of complex problems, including airway reconstruction, aerodigestive disorders, surgical treatment of obstructive sleep apnea, and hearing loss and cochlear implantation. He also completed a PhD in developmental biology at Caltech, and his current research focuses on stem cell and regenerative medicine based approaches to laryngeal and tracheal reconstruction and prevention of stenosis.

Dr. Hochstim’s clinical interests include: complex airway disorders, children with tracheostomy, stridor and noisy breathing, drooling and aspiration, subglottic and tracheal stenosis, voice disorders, vocal cord paralysis, laryngomalacia, obstructive sleep apnea, hearing loss, cholesteatoma, head and neck masses and tumors

• Implementation of Child Life Specialists to improve outcomes in flexible endoscopic evaluation of swallowing in children Int J Pediatr Otorhinolaryngol. 2025 Mar; 190:112266. . View in PubMed
• Repurposing of a gill gene regulatory program for outer-ear evolution Nature. 2025 Jan 09. . View in PubMed
• Pediatric Invasive Fungal Rhinosinusitis: A Comprehensive Analysis of Prognostic Factors for Survival Laryngoscope. 2023 05; 133(5):1239-1250. . View in PubMed
• Identifying Posterior Fossa Abnormality in Pediatric Aerodigestive Patients, a Case Series Ann Otol Rhinol Laryngol. 2023 Mar; 132(3):341-345. . View in PubMed
• Disparities in Access to Pediatric Otolaryngology Care During the COVID-19 Pandemic Ann Otol Rhinol Laryngol. 2022 Sep; 131(9):971-978. . View in PubMed
• Preoperative SARS-CoV-2 Screening Fails to Detect Viral Particles Prior to Airway Surgery Laryngoscope. 2022 08; 132(8):1665-1667. . View in PubMed
• The effect of anesthesia without opioid on perioperative opioid demand in children with severe obstructive sleep apnea (OSA) for adenotonsillectomies – single-center retrospective observational study JA Clin Rep. 2022 Jun 14; 8(1):41. . View in PubMed
• Postoperative respiratory adverse events in children after endoscopic laryngeal cleft repair Eur Arch Otorhinolaryngol. 2022 May; 279(5):2689-2693. . View in PubMed
• Perioperative respiratory adverse events in children undergoing triple endoscopy Paediatr Anaesth. 2021 Dec; 31(12):1290-1297. . View in PubMed
• Risk factors for peri-operative respiratory adverse events after supraglottoplasty Int J Pediatr Otorhinolaryngol. 2021 Oct; 149:110853. . View in PubMed
• Tracheal squamous metaplasia in children with endotracheal intubation or tracheostomy Int J Pediatr Otorhinolaryngol. 2021 Jan; 140:110549. . View in PubMed
• Factors impacting participation in flexible endoscopic evaluation of swallowing in children Int J Pediatr Otorhinolaryngol. 2020 Nov; 138:110323. . View in PubMed
• Safety and efficacy of Early injection laryngoplasty in pediatric patients Laryngoscope. 2019 07; 129(7):1699-1705. . View in PubMed
• Differential epithelial growth in tissue-engineered larynx and trachea generated from postnatal and fetal progenitor cells Biochem Biophys Res Commun. 2019 03 05; 510(2):205-210. . View in PubMed
• Geographic health disparities in the Los Angeles pediatric neck abscess population Int J Pediatr Otorhinolaryngol. 2018 Oct; 113:134-139. . View in PubMed
• Geographic health disparities in the Los Angeles pediatric esophageal foreign body population Int J Pediatr Otorhinolaryngol. 2018 Mar; 106:85-90. . View in PubMed
• Establishing Proximal and Distal Regional Identities in Murine and Human Tissue-Engineered Lung and Trachea Tissue Eng Part C Methods. 2016 11; 22(11):1049-1057. . View in PubMed
• Bacterial biofilms and increased bacterial counts are associated with airway stenosis Otolaryngol Head Neck Surg. 2014 May; 150(5):834-40. . View in PubMed
• A novel orthotopic mouse model of head and neck cancer and lymph node metastasis Oncogenesis. 2013 Sep 09; 2:e68. . View in PubMed
• Relationship of eosinophils and plasma cells to biofilm in chronic rhinosinusitis Am J Rhinol Allergy. 2013 Jul-Aug; 27(4):e85-90. . View in PubMed
• Gold nanorod-sphingosine kinase siRNA nanocomplexes: a novel therapeutic tool for potent radiosensitization of head and neck cancer Integr Biol (Camb). 2012 Feb; 4(2):132-41. . View in PubMed
• Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition Head Neck. 2011 Feb; 33(2):178-88. . View in PubMed
• Biofilm and persistent inflammation in endoscopic sinus surgery Otolaryngol Head Neck Surg. 2010 Nov; 143(5):697-8. . View in PubMed
• Biofilm detection with hematoxylin-eosin staining Arch Otolaryngol Head Neck Surg. 2010 May; 136(5):453-6. . View in PubMed
• Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code Cell. 2008 May 02; 133(3):510-22. . View in PubMed
• The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord Neuron. 2006 Dec 21; 52(6):953-68. . View in PubMed

• Johns, Michael
• Demetriades, Demetrios
• Hur, Kevin
• Zada, Gabriel