Faculty

Christopher P. Gayer, MD, PhD
Christopher P. Gayer, MD, PhD
Assistant Professor of Clinical Surgery
Pediatrics
CHL 4650 W Sunset Blvd Off Campus Los Angeles
I am interested in bile acid metabolism and how specific bile acid receptors, such as FXR, influence the intestinal epithelial barrier in injury models

Variability in perioperative evaluation and resource utilization in pediatric patients with suspected biliary dyskinesia: A multi-institutional retrospective cohort study J Pediatr Surg. 2019 Jun; 54(6):1118-1122. . View in PubMed

Screening for blunt cerebrovascular injuries in pediatric trauma patients J Pediatr Surg. 2019 Apr 25. . View in PubMed

Pilot Study of the Effect of Plant-Based Enteral Nutrition on the Gut Microbiota in Chronically Ill Tube-Fed Children JPEN J Parenter Enteral Nutr. 2019 Jan 15. . View in PubMed

Closing gastroschisis: The good, the bad, and the not-so ugly J Pediatr Surg. 2019 Jan; 54(1):60-64. . View in PubMed

Closing gastroschisis: The good, the bad, and the not-so ugly J Pediatr Surg. 2018 Oct 05. . View in PubMed

Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms Am J Physiol Gastrointest Liver Physiol. 2018 Aug 01; 315(2):G259-G271. . View in PubMed

Liquid chromatography-mass spectroscopy in the diagnosis of biliary atresia in children with hyperbilirubinemia J Surg Res. 2018 Aug; 228:228-237. . View in PubMed

Soybean-derived recombinant human epidermal growth factor protects against experimental necrotizing enterocolitis J Pediatr Surg. 2018 Jun; 53(6):1203-1207. . View in PubMed

Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms Am J Physiol Gastrointest Liver Physiol. 2018 Apr 19. . View in PubMed

Soybean-derived recombinant human epidermal growth factor protects against experimental necrotizing enterocolitis J Pediatr Surg. 2018 Mar 08. . View in PubMed

Liquid chromatography-mass spectroscopy in the diagnosis of biliary atresia in children with hyperbilirubinemia J Surg Res. 2018 08; 228:228-237. . View in PubMed

Lactobacillus murinus HF12 colonizes neonatal gut and protects rats from necrotizing enterocolitis PLoS One. 2018; 13(6):e0196710. . View in PubMed

Discussion of: "Hospital admission unnecessary for successful uncomplicated radiographic reduction of pediatric intussusception" Am J Surg. 2017 Dec; 214(6):1208-1209. . View in PubMed

Hospital admission unnecessary for successful uncomplicated radiographic reduction of pediatric intussusception Am J Surg. 2017 Dec; 214(6):1203-1207. . View in PubMed

Advances in paediatric gastroenterology Lancet. 2017 Sep 09; 390(10099):1072-1082. . View in PubMed

Routine post-operative esophagram Is not necessary after repair of esophageal atresia Am J Surg. 2017 Apr; 213(4):640-644. . View in PubMed

Re-evaluation of liver transaminase cutoff for CT after pediatric blunt abdominal trauma Pediatr Surg Int. 2017 Mar; 33(3):311-316. . View in PubMed

Discussion of: "Hospital admission unnecessary for successful uncomplicated radiographic reduction of pediatric intussusception" Am J Surg. 2017 12; 214(6):1208-1209. . View in PubMed

Liquid chromatography-mass spectroscopy as a tool in the rapid diagnosis of biliary atresia: a pilot study J Pediatr Surg. 2016 Jun; 51(6):923-6. . View in PubMed

An ectopic renin-secreting adrenal corticoadenoma in a child with malignant hypertension Physiol Rep. 2016 Mar; 4(5). . View in PubMed

Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling Am J Physiol Gastrointest Liver Physiol. 2016 Jan 15; 310(2):G81-92. . View in PubMed

Liver steatosis induced by small bowel resection is prevented by oral vancomycin Surgery. 2016 12; 160(6):1485-1495. . View in PubMed

Limiting chest computed tomography in the evaluation of pediatric thoracic trauma J Trauma Acute Care Surg. 2016 08; 81(2):271-7. . View in PubMed

Admission hematocrit predicts the need for transfusion secondary to hemorrhage in pediatric blunt trauma patients J Trauma Acute Care Surg. 2015 Oct; 79(4):555-62. . View in PubMed

Images in clinical medicineGastric emphysema. N Engl J Med. 2014 May 29; 370(22):e33. . View in PubMed

Recent developments in Hirschsprung's-associated enterocolitis Curr Gastroenterol Rep. 2013 Aug; 15(8):340. . View in PubMed

Necrotizing enterocolitis: contemporary management and outcomes Adv Pediatr. 2013; 60(1):263-79. . View in PubMed

Isolated ruptured appendicitis presenting as pneumatosis intestinalis in a premature neonate Pediatr Surg Int. 2012 Apr; 28(4):439-41. . View in PubMed

Combined endoscopic and laparoscopic approach to a gastroesophageal tumor JSLS. 2011 Apr-Jun; 15(2):228-31. . View in PubMed

ERK regulates strain-induced migration and proliferation from different subcellular locations J Cell Biochem. 2010 Mar 01; 109(4):711-25. . View in PubMed

Acute lower gastrointestinal bleeding in 1,112 patients admitted to an urban emergency medical center Surgery. 2009 Oct; 146(4):600-6; discussion 606-7. . View in PubMed

The effects of increased extracellular deformation, pressure, and integrin phosphorylation on fibroblast migration J Surg Res. 2009 Sep; 156(1):103-9. . View in PubMed

The effects of mechanical forces on intestinal physiology and pathology Cell Signal. 2009 Aug; 21(8):1237-44. . View in PubMed

Delineating the signals by which repetitive deformation stimulates intestinal epithelial migration across fibronectin Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G876-85. . View in PubMed

Strain-induced proliferation requires the phosphatidylinositol 3-kinase/AKT/glycogen synthase kinase pathway J Biol Chem. 2009 Jan 23; 284(4):2001-11. . View in PubMed

Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789 Am J Physiol Cell Physiol. 2009 Jan; 296(1):C193-204. . View in PubMed

Supraphysiologic extracellular pressure inhibits intestinal epithelial wound healing independently of luminal nutrient flow Am J Surg. 2008 Nov; 196(5):683-9. . View in PubMed

Repetitive deformation activates Src-independent FAK-dependent ERK motogenic signals in human Caco-2 intestinal epithelial cells Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1350-61. . View in PubMed

Clinical evaluation and management of caustic injury in the upper gastrointestinal tract in 95 adult patients in an urban medical center Surg Endosc. 2008 Apr; 22(4):1119-25. . View in PubMed

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