Brian P. Lee, MD

Dr. Lee is a transplant hepatologist who treats patients before and after liver transplant. His NIAAA-funded research program focuses on improving health for patients with alcohol use and liver disease, through: 1) early transplant in alcohol hepatitis; 2) intersection of alcohol and obesity in the liver; 3) health inequities; 4) public policy and advocacy; 5) novel therapies and translational science. His research has led to first-author studies in Annals of Internal Medicine, Lancet Public Health, JAMA Internal Medicine, Gastroenterology, Journal of Hepatology, among others. His research has featured in New York Times, Washington Post, NBC Nightly News, Today Show, NPR, CNN, Forbes, Los Angeles Times, Wall Street Journal, among others. He has led advocacy initiatives that successfully changed national- and state-wide transplant and insurance policies to improve healthcare access for patients. His research has incorporated into practice guidelines across North America, Europe, Latin America, and Asia. He has served as a voting member on the FDA Gastrointestinal Drugs Advisory Committee.

• European Association for the Study of the Liver: Young Investigator Bursary Award, 2019
• American Association for the Study of Liver Diseases: Clinical/Translational Early Career Investigator Award, 2018
• American Society of Transplantation: Young Investigator Award, 2018
• International Liver Transplantation Society: Young Investigator Award, 2017
• Johns Hopkins Hospital: Resident Teaching Award, 2016
• Summa Cum Laude, 2013
• Alpha Omega Alpha (AOA), 2013
• Phi Beta Kappa, 2010

• Longitudinal Change of Alcohol Use is a Dynamic Contributor to Steatotic Liver Disease Progression Gastroenterology. 2024 Mar 28. . View in PubMed
• National prevalence estimates for steatotic liver disease and subclassifications using consensus nomenclature Hepatology. 2024 Mar 01; 79(3):666-673. . View in PubMed
• Meta-analysis: Prevalence and impact of alcohol abstinence in alcohol-associated cirrhosis Aliment Pharmacol Ther. 2024 Mar; 59(6):730-741. . View in PubMed
• The Global Burden of Alcohol-associated Cirrhosis and Cancer in Young and Middle-aged Adults Clin Gastroenterol Hepatol. 2024 Feb 28. . View in PubMed
• Association of Renin-Angiotensin System Inhibition With Liver-Related Events and Mortality in Compensated CirrhosisClin Gastroenterol Hepatol. 2024 02; 22(2):315-323. e17. . View in PubMed
• Association between neighborhood-based material deprivation and liver transplant waitlist registrants demographics and mortality Clin Transplant. 2024 Jan; 38(1):e15189. . View in PubMed
• Reply: Recognizing the new nomenclature requires a comprehensive analysis of the prevalence, severity, and long-term outlook for SLD and subclassifications Hepatology. 2023 Oct 31. . View in PubMed
• Liver transplantation for alcohol-associated liver disease: A call for national standards of best practices to monitor and bridge disparities in access and outcomes Am J Transplant. 2023 08; 23(8):1097-1101. . View in PubMed
• Healthcare affordability and effects on mortality among adults with liver disease from 2004 to 2018 in the United States J Hepatol. 2023 08; 79(2):329-339. . View in PubMed
• Geographic Density of Gastroenterologists Is Associated With Decreased Mortality From Alcohol-Associated Liver DiseaseClin Gastroenterol Hepatol. 2023 06; 21(6):1542-1551. e6. . View in PubMed
• National Trends in Alcohol Use, Metabolic Syndrome, and Liver Disease From 1999 to 2018 Ann Intern Med. 2023 06; 176(6):879-882. . View in PubMed
• Liver transplant for alcohol-associated liver disease continues to rise 2 years into the COVID-19 pandemic especially among young adults J Hepatol. 2023 04; 78(4):e139-e141. . View in PubMed
• Quantifying days at home in patients with cirrhosis: A national cohort study Hepatology. 2023 08 01; 78(2):518-529. . View in PubMed
• Multicentered study of patient outcomes after declined for early liver transplantation in severe alcohol-associated hepatitis Hepatology. 2023 04 01; 77(4):1253-1262. . View in PubMed
• Subclinical hepatic fibrosis is associated with coronary microvascular dysfunction by myocardial perfusion reserve index: a retrospective cohort study Int J Cardiovasc Imaging. 2022 Feb 02. . View in PubMed
• Advocacy for Equity in Transplantation Access for Alcohol-Associated Liver Disease: How Research Changed Medi-Cal Policy Gastroenterology. 2022 09; 163(3):539-542. . View in PubMed
• Duration and cost-effectiveness of hepatocellular carcinoma surveillance in hepatitis C patients after viral eradication J Hepatol. 2022 07; 77(1):55-62. . View in PubMed
• Artificial intelligence to identify harmful alcohol use after early liver transplant for alcohol-associated hepatitis Am J Transplant. 2022 07; 22(7):1834-1841. . View in PubMed
• Alcohol use trajectories among US. adults during the first 42 weeks of the COVID-19 pandemic. Alcohol Clin Exp Res. 2022 06; 46(6):1062-1072. . View in PubMed
• Discordance in categorization of acute-on-chronic liver failure in the United Network for Organ Sharing database J Hepatol. 2022 05; 76(5):1122-1126. . View in PubMed
• Patterns of Alcohol Use After Early Liver Transplantation for Alcoholic HepatitisClin Gastroenterol Hepatol. 2022 02; 20(2):409-418. e5. . View in PubMed
• Medicaid expansion and variability in mortality in the USA: a national, observational cohort study Lancet Public Health. 2022 01; 7(1):e48-e55. . View in PubMed
• Early Liver Transplantation for Severe Alcohol-Associated Hepatitis and a History of Prior Liver Decompensation Am J Gastroenterol. 2022 12 01; 117(12):1990-1998. . View in PubMed
• Changes and mediators of survival disparity among Black liver transplant recipients in the United States Am J Transplant. 2021 12; 21(12):3883-3893. . View in PubMed
• Retail Alcohol and Tobacco Sales During COVID-19 Ann Intern Med. 2021 07; 174(7):1027-1029. . View in PubMed
• Bariatric surgery and the risk of alcohol-related cirrhosis and alcohol misuse Liver Int. 2021 05; 41(5):1012-1019. . View in PubMed
• Excess Mortality After Liver Transplantation in Young Women With Alcohol-Associated Liver Disease Am J Gastroenterol. 2021 03 01; 116(3):551-559. . View in PubMed
• Medicaid Policy and Liver Transplant for Alcohol-Associated Liver Disease Hepatology. 2020 07; 72(1):130-139. . View in PubMed
• Liver Transplantation in Unauthorized Immigrants in the United States Hepatology. 2020 05; 71(5):1802-1812. . View in PubMed
• Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes Liver Transpl. 2020 04; 26(4):498-506. . View in PubMed
• Early Liver Transplantation for Alcohol-Associated Liver Disease: Need for Engagement and Education of All Stakeholders Hepatol Commun. 2019 Aug; 3(8):1019-1021. . View in PubMed
• Model to Calculate Harms and Benefits of Early vs Delayed Liver Transplantation for Patients With Alcohol-Associated HepatitisGastroenterology. 2019 08; 157(2):472-480. e5. . View in PubMed
• Underestimation of Liver Transplantation for Alcoholic Hepatitis in the National Transplant Database Liver Transpl. 2019 05; 25(5):706-711. . View in PubMed
• Predicting Low Risk for Sustained Alcohol Use After Early Liver Transplant for Acute Alcoholic Hepatitis: The Sustained Alcohol Use Post-Liver Transplant Score Hepatology. 2019 04; 69(4):1477-1487. . View in PubMed
• Reply Gastroenterology. 2019 01; 156(1):286-287. . View in PubMed
• Liver-related mortality in the United States: hepatitis C declines, non-alcoholic fatty liver and alcohol rise Transl Gastroenterol Hepatol. 2019; 4:19. . View in PubMed
• National Trends and Long-term Outcomes of Liver Transplant for Alcohol-Associated Liver Disease in the United States JAMA Intern Med. 2019 03 01; 179(3):340-348. . View in PubMed
• Return to Alcohol Use After Liver Transplant: Patterns and Surveillance Clin Liver Dis (Hoboken). 2018 Dec; 12(6):160-164. . View in PubMed
• Outcomes of Early Liver Transplantation for Patients With Severe Alcoholic HepatitisGastroenterology. 2018 08; 155(2):422-430. e1. . View in PubMed
• Early liver transplantation for severe alcoholic hepatitis: moving from controversy to consensus Curr Opin Organ Transplant. 2018 04; 23(2):229-236. . View in PubMed
• Alcohol Abuse and Liver Disease Gastroenterology. 2018; 154(1):254-255. . View in PubMed
• Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B J Hepatol. 2017 02; 66(2):275-281. . View in PubMed
• Three-year Results of a Pilot Program in Early Liver Transplantation for Severe Alcoholic Hepatitis Ann Surg. 2017 01; 265(1):20-29. . View in PubMed
• Recessive NPHS2 (Podocin) mutations are rare in adult-onset idiopathic focal segmental glomerulosclerosis Clin J Am Soc Nephrol. 2007 Jan; 2(1):31-7. . View in PubMed
• Bullous “cellulitis” with eosinophilia: case report and review of Wells’ syndrome in childhood Pediatrics. 2005 Jul; 116(1):e149-55. . View in PubMed

• Terrault, Norah
• Tsukamoto, Hidekazu
• Emamaullee, Juliet
• Genyk, Yuri