Larry Liang Wang, MD, PhD

Research in Progress: RNA expression profile in bone and soft tissue; Undifferentiated neuroblastoma: biology and morphology and; Pediatric liver diseases .

• Undifferentiated embryonal sarcoma of the liver: A clinicopathological and genomic study of 10 cases from a single institution. Hum Pathol. 2025 Nov; 165:105935.. View in PubMed
• Non-Tobacco Nicotine Use and Complications in Free Flap Repair in Head and Neck Cancer. Laryngoscope. 2025 Oct; 135(10):3630-3638.. View in PubMed
• Data set for reporting of peripheral neuroblastic tumours: recommendations from the international collaboration on cancer reporting (ICCR). Histopathology. 2025 Sep; 87(3):343-356.. View in PubMed
• Pediatric Embryonal Rhabdomyosarcoma: An Integrated Study of Clinicopathological Features, Pan-cancer Targeted Next-generation Sequencing, and Chromosomal Microarray Analysis from a Single Institution. Virchows Arch. 2025 Aug 14.. View in PubMed
• Clinical and pathological features of pediatric peripheral T-cell lymphoma after solid organ transplantation. Blood Neoplasia. 2024 Dec; 1(4):100039.. View in PubMed
• A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration. Bioact Mater. 2024 Nov; 41:553-563.. View in PubMed
• Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors. Transl Pediatr. 2024 Apr 30; 13(4):624-633.. View in PubMed
• Comparative Clinicopathologic and Genomic Analysis of Hepatocellular Neoplasm, Not Otherwise Specified, and Hepatoblastoma. Mod Pathol. 2024 Feb; 37(2):100385.. View in PubMed
• Pediatric Sertoli-Leydig Cell Tumors of the Ovary: An Integrated Study of Clinicopathological Features, Pan-cancer-Targeted Next-generation Sequencing and Chromosomal Microarray Analysis From a Single Institution. Am J Surg Pathol. 2024 Feb 01; 48(2):194-203.. View in PubMed
• FGFR1 gene fusions in a subset of pediatric mesenchymal tumors: Expanding the genetic spectrum of tumors sharing histologic overlap with infantile fibrosarcoma and “NTRK-rearranged” spindle cell neoplasms. Genes Chromosomes Cancer. 2023 11; 62(11):641-647.. View in PubMed
• Prominin-1 promotes restitution of the murine extrahepatic biliary luminal epithelium following cholestatic liver injury. Hepatol Commun. 2023 01 20; 7(2):e0018.. View in PubMed
• An Integrative Morphologic and Molecular Approach for Diagnosis and Subclassification of Rhabdomyosarcoma. Arch Pathol Lab Med. 2022 08 01; 146(8):953-959.. View in PubMed
• Independent Assessment of the Children’s Hepatic Tumors International Collaboration Risk Stratification for Hepatoblastoma and the Association of Tumor Histological Characteristics With Prognosis. JAMA Netw Open. 2022 02 01; 5(2):e2148013.. View in PubMed
• Clinicopathologic Characteristics of Late Acute Antibody-mediated Rejection in Pediatric Liver Transplantation. Transplantation. 2021 09 01; 105(9):2045-2053.. View in PubMed
• Massive unilateral fetal axillary lymphangioma: A case report. Case Rep Womens Health. 2021 Jul; 31:e00319.. View in PubMed
• Pediatric Benign Tumors With a Skeletal Muscle Component: Myogenin Expression, Diagnostic Pitfalls, and New Molecular Insights. Pediatr Dev Pathol. 2021 May-Jun; 24(3):213-226.. View in PubMed
• Primary Knee Intra-articular Synovial Sarcoma in Pediatric and Adolescent Patients. Pediatr Dev Pathol. 2021 Mar-Apr; 24(2):159-163.. View in PubMed
• Custom Pediatric Oncology Next-Generation Sequencing Panel Identifies Somatic Mosaicism in Archival Tissue and Enhances Targeted Clinical Care. Pediatr Neurol. 2021 01; 114:55-59.. View in PubMed
• Phox2b Immunohistochemical Staining in Detecting Enteric Neural Crest Cells in Hirschsprung Disease. Pediatr Dev Pathol. 2021 Jan-Feb; 24(1):19-26.. View in PubMed
• Histopathologic features of alveolar capillary dysplasia with misalignment of pulmonary veins with atypical clinical presentation. Cardiovasc Pathol. 2021 Jan – Feb; 50:107289.. View in PubMed
• Initiation of immunotherapy with activated natural killer cells and anti-GD2 antibody dinutuximab prior to resection of primary neuroblastoma prolongs survival in mice. J Immunother Cancer. 2020 12; 8(2).. View in PubMed
• A 6-Year-Old Boy With a Mediastinal Mass. Chest. 2020 12; 158(6):e317-e321.. View in PubMed
• Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome. Thorax. 2020 06; 75(6):486-493.. View in PubMed
• The Clinical Management and Outcomes of Pelvic Neuroblastic Tumors. J Surg Res. 2020 05; 249:8-12.. View in PubMed
• Older Age Is Associated with Decreased Levels of VDR, CYP27B1, and CYP24A1 and Increased Levels of PTH in Human Parathyroid Glands. Int J Endocrinol. 2020; 2020:7257913.. View in PubMed
• Ewing-like sarcoma/undifferentiated round cell sarcoma in an infant with APC and MSH6 variation: A case report. Medicine (Baltimore). 2019 Nov; 98(45):e17872.. View in PubMed
• Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation. Sci Rep. 2019 03 28; 9(1):5296.. View in PubMed
• Activated Natural Killer Cells in Combination with Anti-GD2 Antibody Dinutuximab Improve Survival of Mice after Surgical Resection of Primary Neuroblastoma. Clin Cancer Res. 2019 01 01; 25(1):325-333.. View in PubMed
• Inflammation, Active Fibroplasia, and End-stage Fibrosis in 172 Biliary Atresia Remnants Correlate Poorly With Age at Kasai Portoenterostomy, Visceral Heterotaxy, and Outcome. Am J Surg Pathol. 2018 12; 42(12):1625-1635.. View in PubMed
• The Use of Fetal Bronchoscopy in the Diagnosis and Management of a Suspected Obstructive Lung Mass. AJP Rep. 2018 Jul; 8(3):e195-e200.. View in PubMed
• MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group. Oncotarget. 2018 Jan 19; 9(5):6416-6432.. View in PubMed
• Hepatocellular malignant neoplasm, NOS: a clinicopathological study of 11 cases from a single institution. Histopathology. 2017 Nov; 71(5):813-822.. View in PubMed
• Melanotic Neuroectodermal Tumor of Infancy Presenting With Fast-Growing Scrotal Swelling: A Case Report and Literature Review. Pediatr Dev Pathol. 2017 Sep-Oct; 20(5):411-415.. View in PubMed
• Glypican 3 as a Serum Marker for Hepatoblastoma. Sci Rep. 2017 04 05; 7:45932.. View in PubMed
• Abdominal Actinomycosis in Children: A Case Report and Literature Review. Pediatr Infect Dis J. 2017 03; 36(3):e76-e79.. View in PubMed
• TGFβR1 Blockade with Galunisertib (LY2157299) Enhances Anti-Neuroblastoma Activity of the Anti-GD2 Antibody Dinutuximab (ch14.18) with Natural Killer Cells. Clin Cancer Res. 2017 Feb 01; 23(3):804-813.. View in PubMed
• Colonization with Escherichia coli EC 25 protects neonatal rats from necrotizing enterocolitis. PLoS One. 2017; 12(11):e0188211.. View in PubMed
• Biological roles and potential applications of immune cell-derived extracellular vesicles. J Extracell Vesicles. 2017; 6(1):1400370.. View in PubMed
• Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization. Am J Pathol. 2016 12; 186(12):3261-3272.. View in PubMed
• Key Histopathologic Features of Liver Biopsies That Distinguish Biliary Atresia From Other Causes of Infantile Cholestasis and Their Correlation With Outcome: A Multicenter Study. Am J Surg Pathol. 2016 12; 40(12):1601-1615.. View in PubMed
• The diagnostic and prognostic value of SALL4 in hepatoblastoma. Histopathology. 2016 Nov; 69(5):822-830.. View in PubMed
• Refractory Kaposiform Hemangioendothelioma Associated with the Chromosomal Translocation t(13;16)(q14;p13.3). Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):417-420.. View in PubMed
• Orthotopic liver transplant for multifocal lymphangioendotheliomatosis with thrombocytopenia. Pediatr Transplant. 2016 May; 20(3):456-9.. View in PubMed
• Hepatocellular carcinoma associated with tight-junction protein 2 deficiency. Hepatology. 2015 Dec; 62(6):1914-6.. View in PubMed
• Quantification of glypican 3, β-catenin and claudin-1 protein expression in hepatoblastoma and paediatric hepatocellular carcinoma by colour deconvolution. Histopathology. 2015 Dec; 67(6):905-13.. View in PubMed
• Imaging Lymphoid Cell Death In Vivo During Polymicrobial Sepsis. Crit Care Med. 2015 Nov; 43(11):2303-12.. View in PubMed
• Insulin-like Growth Factor 2 Gene Expression Molecularly Differentiates Pleuropulmonary Blastoma and Embryonal Rhabdomyosarcoma. J Pediatr Hematol Oncol. 2015 Aug; 37(6):e356-60.. View in PubMed
• Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. J Clin Immunol. 2015 Jul; 35(5):435-8.. View in PubMed
• Is INI1-retained small cell undifferentiated histology in hepatoblastoma unfavorable? Hum Pathol. 2015 Apr; 46(4):620-4.. View in PubMed
• Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-γ1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma. Int J Clin Exp Pathol. 2015; 8(8):9042-51.. View in PubMed
• Inhibition of 4-nitroquinoline-1-oxide-induced oral carcinogenesis by dietary calcium. Int J Clin Exp Pathol. 2015; 8(4):3529-42.. View in PubMed
• Age-dependent prognostic effect by Mitosis-Karyorrhexis Index in neuroblastoma: a report from the Children’s Oncology Group. Pediatr Dev Pathol. 2014 Nov-Dec; 17(6):441-9.. View in PubMed
• The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis. Am J Pathol. 2014 Oct; 184(10):2768-78.. View in PubMed
• Synchronous HIV/AIDS-related Epstein-Barr Virus-associated smooth muscle tumors in a 20-year-old female. Pediatr Infect Dis J. 2014 Oct; 33(10):1055-6.. View in PubMed
• Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia. Hepatology. 2014 Sep; 60(3):941-53.. View in PubMed
• Percutaneous liver biopsy: pathologic diagnosis and complications in children. J Pediatr Gastroenterol Nutr. 2013 Nov; 57(5):644-8.. View in PubMed
• Teratoid hepatoblastoma with abundant cholangioblastic component in a child with full trisomy 13. Pediatr Dev Pathol. 2013 Nov-Dec; 16(6):438-41.. View in PubMed
• Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: a report from the Children’s Oncology Group. Cancer. 2013 Oct 15; 119(20):3718-26.. View in PubMed
• Inflammatory myofibroblastic tumors in childhood. Pediatr Hematol Oncol. 2013 Oct; 30(7):640-5.. View in PubMed
• Simultaneous colonic adenocarcinoma and medulloblastoma in a 12-year-old with biallelic deletions in PMS2. J Pediatr. 2013 Aug; 163(2):601-3.. View in PubMed
• Subcutaneous Panniculitis-like T-cell lymphoma in two pediatric patients: an HIV-positive adolescent and a 4-month-old infant. Fetal Pediatr Pathol. 2013 Jun; 32(3):175-83.. View in PubMed
• Peripheral neuroblastic tumors with genotype-phenotype discordance: a report from the Children’s Oncology Group and the International Neuroblastoma Pathology Committee. Pediatr Blood Cancer. 2013 Mar; 60(3):363-70.. View in PubMed
• Tumor necrosis predicts survival following neo-adjuvant chemotherapy for hepatoblastoma. Pediatr Blood Cancer. 2012 Sep; 59(3):493-8.. View in PubMed
• Pleuropulmonary blastoma: a single-institution experience. J Pediatr Hematol Oncol. 2012 Jul; 34(5):e182-5.. View in PubMed
• Role of interleukin-10 in the pathogenesis of necrotizing enterocolitis. Am J Surg. 2012 Apr; 203(4):428-35.. View in PubMed
• [Pathology of peripheral neuroblastic tumors]. Zhonghua Bing Li Xue Za Zhi. 2012 Apr; 41(4):283-8.. View in PubMed
• P-glycoprotein induction by breast milk attenuates intestinal inflammation in experimental necrotizing enterocolitis. Lab Invest. 2011 Nov; 91(11):1668-79.. View in PubMed
• Recruitment of dendritic cells is responsible for intestinal epithelial damage in the pathogenesis of necrotizing enterocolitis by Cronobacter sakazakii. J Immunol. 2011 Jun 15; 186(12):7067-79.. View in PubMed
• Effects of neoadjuvant chemotherapy on hepatoblastoma: a morphologic and immunohistochemical study. Am J Surg Pathol. 2010 Mar; 34(3):287-99.. View in PubMed
• Primary gastric tumors of infancy and childhood: 54-year experience at a single institution. J Pediatr Surg. 2008 Aug; 43(8):1487-93.. View in PubMed

• Mascarenhas, Leo
• Warburton, David
• Lenz, Heinz-Josef
• Minoo, Parviz
• Asgharzadeh, Shahab
• Crandall, Edward
• Chi, Yueh-Yun
• Pawel, Bruce
• McMahon, Andrew
• Matsuo, Koji
• Biegel, Jaclyn
• Krailo, Mark
• Barkauskas, Donald
• Zhou, Shengmei
• Gonzalez, Frank
• Terrault, Norah