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Christina J. Azevedo, MD

Associate Professor of Clinical Neurology

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Email [email protected]
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Publications

  • Probabilistic brain MR image transformation using generative models. Sci Rep. 2025 Dec 20; 16(1):2161.. View in PubMed
  • 2024 MAGNIMS-CMSC-NAIMS consensus recommendations on the use of MRI for the diagnosis of multiple sclerosis. Lancet Neurol. 2025 Oct; 24(10):866-879.. View in PubMed
  • Frequency and Diagnostic Implications of Paramagnetic Rim Lesions in People Presenting for Diagnosis to a Multiple Sclerosis Clinic. Neurology. 2025 Sep 23; 105(6):e213912.. View in PubMed
  • Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis. AJNR Am J Neuroradiol. 2025 Mar 04; 46(3):620-626.. View in PubMed
  • Analysis of healthcare utilization before the diagnosis of radiologically isolated syndrome. Mult Scler. 2025 Feb; 31(2):184-196.. View in PubMed
  • Incorporation of the central vein sign into the McDonald criteria. Mult Scler Relat Disord. 2025 Jan; 93:106182.. View in PubMed
  • Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study. J Neuroimaging. 2025 Jan-Feb; 35(1):e70011.. View in PubMed
  • Early Disease-Modifying Treatments for Presymptomatic Multiple Sclerosis. CNS Drugs. 2024 Dec; 38(12):973-983.. View in PubMed
  • Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis. J Neuroimaging. 2024 Nov-Dec; 34(6):750-757.. View in PubMed
  • Imaging chronic active lesions in multiple sclerosis: a consensus statement. Brain. 2024 Sep 03; 147(9):2913-2933.. View in PubMed
  • Dimethyl fumarate preserves brainstem and cervical spinal cord integrity in radiologically isolated syndrome. J Neurol. 2024 Sep; 271(9):5899-5910.. View in PubMed
  • Choroid plexus enlargement correlates with periventricular pathology but not with disease activity in radiologically isolated syndrome. Mult Scler. 2024 Sep; 30(10):1278-1289.. View in PubMed
  • Diagnostic performance of central vein sign versus oligoclonal bands for multiple sclerosis. Mult Scler. 2024 Sep; 30(10):1268-1277.. View in PubMed
  • Choroid plexus volume differentiates MS from its mimics. Mult Scler. 2024 Jul; 30(8):1072-1076.. View in PubMed
  • The diagnostic workup of children with the radiologically isolated syndrome differs by age and by sex. J Neurol. 2024 Jul; 271(7):4019-4027.. View in PubMed
  • The diagnostic value of the central vein sign in radiologically isolated syndrome. Ann Clin Transl Neurol. 2024 Mar; 11(3):662-672.. View in PubMed
  • Recent Advances in Diagnostic, Prognostic, and Disease-Monitoring Biomarkers in Multiple Sclerosis. Neurol Clin. 2024 Feb; 42(1):15-38.. View in PubMed
  • A multicenter pilot study evaluating simplified central vein assessment for the diagnosis of multiple sclerosis. Mult Scler. 2024 Jan; 30(1):25-34.. View in PubMed
  • Author Correction: Toward precision medicine using a “digital twin” approach: modeling the onset of disease-specific brain atrophy in individuals with multiple sclerosis. Sci Rep. 2023 Dec 15; 13(1):22334.. View in PubMed
  • Radiologically isolated syndrome. Lancet Neurol. 2023 11; 22(11):1075-1086.. View in PubMed
  • Teriflunomide and Time to Clinical Multiple Sclerosis in Patients With Radiologically Isolated Syndrome: The TERIS Randomized Clinical Trial. JAMA Neurol. 2023 10 01; 80(10):1080-1088.. View in PubMed
  • Toward precision medicine using a “digital twin” approach: modeling the onset of disease-specific brain atrophy in individuals with multiple sclerosis. Sci Rep. 2023 09 28; 13(1):16279.. View in PubMed
  • The radiologically isolated syndrome: revised diagnostic criteria. Brain. 2023 08 01; 146(8):3431-3443.. View in PubMed
  • Toward Precision Medicine Using a “Digital Twin” Approach: Modeling the Onset of Disease-Specific Brain Atrophy in Individuals with Multiple Sclerosis. Res Sq. 2023 May 02.. View in PubMed
  • High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trial. EClinicalMedicine. 2023 May; 59:101957.. View in PubMed
  • Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome. Ann Neurol. 2023 03; 93(3):604-614.. View in PubMed
  • Effect of GBCA Use on Detection and Diagnostic Performance of the Central Vein Sign: Evaluation Using a 3-T FLAIR* Sequence in Patients With Suspected Multiple Sclerosis. AJR Am J Roentgenol. 2023 01; 220(1):115-125.. View in PubMed
  • Neurofilament Light Chain Levels Are Predictive of Clinical Conversion in Radiologically Isolated Syndrome. Neurol Neuroimmunol Neuroinflamm. 2023 01; 10(1).. View in PubMed
  • Risk Factors and Time to Clinical Symptoms of Multiple Sclerosis Among Patients With Radiologically Isolated Syndrome. JAMA Netw Open. 2021 10 01; 4(10):e2128271.. View in PubMed
  • Deep grey matter injury in multiple sclerosis: a NAIMS consensus statement. Brain. 2021 08 17; 144(7):1974-1984.. View in PubMed
  • Cerebellar volume loss in radiologically isolated syndrome. Mult Scler. 2021 01; 27(1):130-133.. View in PubMed
  • New cases of vasculitis after alemtuzumab. Mult Scler. 2020 10; 26(12):1606-1608.. View in PubMed
  • Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis and Myelitis in COVID-19. J Neuroophthalmol. 2020 09; 40(3):398-402.. View in PubMed
  • Contribution of normal aging to brain atrophy in MS. Neurol Neuroimmunol Neuroinflamm. 2019 11; 6(6).. View in PubMed
  • Intracerebral haemorrhage during alemtuzumab administration. Lancet Neurol. 2019 04; 18(4):329-331.. View in PubMed
  • Imaging outcome measures of neuroprotection and repair in MS: A consensus statement from NAIMS. Neurology. 2019 03 12; 92(11):519-533.. View in PubMed
  • Body mass index, but not vitamin D status, is associated with brain volume change in MS. Neurology. 2018 12 11; 91(24):e2256-e2264.. View in PubMed
  • Cervical spinal cord atrophy: An early marker of progressive MS onset. Neurol Neuroimmunol Neuroinflamm. 2018 Mar; 5(2):e435.. View in PubMed
  • Thalamic atrophy in multiple sclerosis: A magnetic resonance imaging marker of neurodegeneration throughout disease. Ann Neurol. 2018 02; 83(2):223-234.. View in PubMed
  • New Concepts Related to Disease Appreciation in Multiple Sclerosis. Neurol Clin. 2018 Feb; 36(1):119-133.. View in PubMed
  • Subcortical grey matter volumes predict subsequent walking function in early multiple sclerosis. J Neurol Sci. 2016 Jul 15; 366:229-233.. View in PubMed
  • Whole-brain atrophy: ready for implementation into clinical decision-making in multiple sclerosis? Curr Opin Neurol. 2016 06; 29(3):237-42.. View in PubMed
  • Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome. Ann Neurol. 2016 Feb; 79(2):288-94.. View in PubMed
  • Longitudinal associations between brain structural changes and fatigue in early MS. Mult Scler Relat Disord. 2016 Jan; 5:29-33.. View in PubMed
  • Early CNS neurodegeneration in radiologically isolated syndrome. Neurol Neuroimmunol Neuroinflamm. 2015 Jun; 2(3):e102.. View in PubMed
  • A comparison of continuous video-EEG monitoring and 30-minute EEG in an ICU. Epileptic Disord. 2014 Dec; 16(4):439-48.. View in PubMed
  • The vitamin D to ameliorate multiple sclerosis (VIDAMS) trial: study design for a multicenter, randomized, double-blind controlled trial of vitamin D in multiple sclerosis. Contemp Clin Trials. 2014 Nov; 39(2):288-93.. View in PubMed
  • In vivo evidence of glutamate toxicity in multiple sclerosis. Ann Neurol. 2014 Aug; 76(2):269-78.. View in PubMed
  • Clinical applications of imaging disease burden in multiple sclerosis: MRI and advanced imaging techniques. Expert Rev Neurother. 2012 Mar; 12(3):323-33.. View in PubMed

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