Daniel A. Oakes, MD

Professor Of Clinical Orthopaedic Surgery

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Overview

Dr. Oakes is a Professor in the Department of Orthopaedic Surgery at the Keck School of Medicine of USC and the Director of the USC Joint Replacement Program.

Dr. Oakes is nationally recognized for his expertise in knee and hip replacement and reconstruction. He has extensive experience with both primary and revision of hip and knee replacement procedures. Dr. Oakes is actively engaged in the role of emerging computer assisted navigation technologies for hip and knee joint replacement procedures and robotic surgery for full and partial knee replacement. Dr. Oakes performed the first robotic total knee surgery at Keck Medical Center of USC in 2018.

Dr. Oakes is interested in the technology advances that improve the longevity implants and patient outcomes. He and his team have worked to develop strategies both to prevent and treat infected joint replacements. His active research focuses on the long-term outcomes of robotic partial and total knee replacement outcomes, of porous metal technology in complex primary and complex revision improving longevity of implant technologies and the prevention and treatment of infected joint replacements, of porous metal technology in complex revision knee replacements, of single stage treatments for infection and of hip resurfacing as an alternative to joint replacement.

Dr. Oakes has consistently been voted a Top Doctor by Pasadena Magazine, Super Doctor by Los Angeles Magazine, and one of America’s Top Doctors by Castle Connolly. He is a fellow in the American Academy of Orthopaedic Surgeons (AAOS). He is a member of the American Association of Hip and Knee Surgeons(AAHKS) and has served as chair of its membership committee.

Dr. Oakes received his medical degree from Harvard Medical School and completed his fellowship training at the Mayo Clinic, where he received the Mark B. Coventry Adult Reconstruction Fellowship Award.

Dr. Oakes is the Joint Replacement fellowship director. He has twice been the recipient of the departments award for teaching excellence.

Awards

  • Pasadena Magazine: Top Doctor, 2010
     – 2019
  • Los Angeles Magazine: Super Doctor, 2016
     – 2022
  • Castle Connolly: America’s Top Doctors, 2014
     – 2020
  • Los Angeles Magazine: Top Doctors, 2018
  • USC: Residency Faculty Teaching Award, 2011
  • USC: Residency Faculty Teaching Award, 2018
  • American Orthopaedic Society for Sports Medicine: Excellence in Research Award, 2002
  • Mayo Clinic: Mark B. Coventry Adult Reconstruction Fellowship Award, 2004

Publications

  • Sobering Outcomes after Two-Stage Revision for Periprosthetic Joint Infection Among Patients Who Have Revision Total Knee Arthroplasty Components. J Arthroplasty. 2026 Sep 19.. View in PubMed
  • The Modular Cup-in-Cup Construct in Revision Total Hip Arthroplasty. Arthroplast Today. 2026 Aug; 40:102114.. View in PubMed
  • Stacked-Cone Constructs for Extensive Tibial and/or Femoral Bone Loss in Complex Primary and Revision TKA: A Multicenter Analysis of 84 Cases. J Bone Joint Surg Am. 2026 Jun 26.. View in PubMed
  • Technology Assistance Mitigates the Volume-Dependent Risk of Hip Dislocation Following Total Hip Arthroplasty. J Bone Joint Surg Am. 2026 Apr 20.. View in PubMed
  • Reply to Letter to the Editor on “A ‘1.5-Stage’ Spacer Construct Using Revision Components for the Management of Periprosthetic Joint Infections of the Knee”. J Arthroplasty. 2026 Apr; 41(4):e29-e31.. View in PubMed
  • Bone Morphogenetic Protein Augmentation of Large Acetabular Defects in Revision Total Hip Arthroplasty: A Viable Option for Massive Bone Loss. Arthroplast Today. 2026 Jun; 39:101998.. View in PubMed
  • Retrograde Ischiopubic Ramus Screw Internal Fixation of a Periprosthetic T-type Acetabular Fracture: A Case Report. JBJS Case Connect. 2025 Jul 01; 15(3).. View in PubMed
  • Stacked Cone Constructs for the Treatment of Extensive Tibial Bone Loss in Revision Total Knee Arthroplasty: A Series of 22 Patients. J Bone Joint Surg Am. 2025 Mar 24; 107(12):1342-1351.. View in PubMed
  • A “1.5-Stage” Spacer Construct Using Revision Components for the Management of Periprosthetic Joint Infection of the Knee. J Arthroplasty. 2025 08; 40(8):1952-1960.. View in PubMed
  • Correction: Limited potential of AAV-mediated gene therapy in transducing human mesenchymal stem cells for bone repair applications. Gene Ther. 2024 Sep; 31(9-10):527.. View in PubMed