Yao Wei Lu, PhD

Assistant Professor of Medicine

Websites

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Awards

American Heart Association (AHA) Second Century Early Faculty Independence Award, 2023

Boston Children's Hospital, Harvard Medical School, Boston, MA — Postdoc — 06/2023 — Cardiovascular Development
Albany Medical College, Albany, NY — Ph.D. — 09/2017 — Cardiovascular Biology
Hardin-Simmons University, Abilene, TX — B.S. — 06/2010 — Biology

DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development. Genes Dev. 2026 07 01; 40(13-14):1029-1044.. View in PubMed
Treatment with the Nox1/4 inhibitor Setanaxib ameliorates cardiac function in mouse models of Duchenne muscular dystrophy. Mol Ther. 2026 Jun 26.. View in PubMed
PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy. Nat Cardiovasc Res. 2026 Apr; 5(4):328-350.. View in PubMed
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts. Clin Sci (Lond). 2025 03 11; 139(5):1-14.. View in PubMed
Trbp inhibits cardiac fibrosis through TGF-β pathway mediated crosstalk between cardiomyocytes and fibroblasts. Clin Sci (Lond). 2025 Feb 19.. View in PubMed
Endothelial FOXM1 and Dab2 promote diabetic wound healing. JCI Insight. 2025 01 23; 10(2).. View in PubMed
Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders. Mol Metab. 2025 Jan; 91:102065.. View in PubMed
Therapeutic Inhibition of LincRNA-p21 Protects Against Cardiac Hypertrophy. Circ Res. 2024 Jul 19; 135(3):434-449.. View in PubMed
The long noncoding RNA CARDINAL attenuates cardiac hypertrophy by modulating protein translation. J Clin Invest. 2024 05 14; 134(13).. View in PubMed
Reduced Mitochondrial Protein Translation Promotes Cardiomyocyte Proliferation and Heart Regeneration. Circulation. 2023 12 05; 148(23):1887-1906.. View in PubMed