Research

Research Highlights

Research in the Department of Cancer Biology spans fundamental and translational cancer biology, with a focus on understanding tumor initiation, progression, and metastasis. Leveraging advanced genomics technologies and AI-driven bioinformatics, we aim to uncover critical molecular pathways and biomarkers for cancer detection, monitoring and treatment. Faculty research programs explore key areas including cancer epigenetics, gene regulation, metabolism, cancer and aging, genomic instability, tumor microenvironment interactions. Our studies encompass a wide range of cancer types, including brain, colorectal, prostate, pancreatic, breast, ovarian, endometrial, leukemia, lung, pediatric cancers, liver, and renal cancers. By integrating cutting-edge technologies with mechanistic studies, our research drives discoveries that inform new strategies for cancer detection, risk assessment, and therapeutic development.

Collaborating with USC Norris Comprehensive Cancer Center

The Department of Cancer Biology at the Keck School of Medicine of USC works closely with the USC Norris Comprehensive Cancer Center (LINK) to advance innovative cancer research and translate scientific discoveries into clinical applications. Faculty members of the department are also active members of USC Norris, leading and contributing to key research programs, shared resources, and strategic initiatives.

This collaboration fosters interdisciplinary studies in cancer epigenetics, genomics, and tumor biology, leveraging the center’s cutting-edge facilities, shared resources and expertise. Together, the department and USC Norris are committed to fundamental cancer research that lead to novel therapeutic strategies and biomarkers to improve patient care.

Through joint research initiatives, leadership in cancer-focused programs, shared resources, and educational training, this partnership strengthens USC’s leadership in cancer research and patient care while advancing discoveries that have a meaningful impact on clinical practice.

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Exterior photo of USC Norris Cancer Center

Powering Discovery Through Sequencing

Established in 2017 and now housed in the Department of Cancer Biology, KGP supports the Keck School of Medicine, USC, and its affiliates with a high-throughput next-generation sequencing ecosystem to help translate the basic code of life. Their mission is to build a collaborative environment and provide a team-driven research platform by implementing next-generation technologies, driving advances in genomics and paving the way towards innovation and personalized medicine.

Explore Keck Genomics Platform