Rael Cahn, MD, PhD

Clinical Associate Professor of Psychiatry & the Behavioral Sciences (Clinician Educator)

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Overview

Dr. Rael Cahn completed his PhD in Neurosciences in 2007 and received his medical degree in 2008 from UC San Diego in La Jolla, CA. He completed his residency with the UC Irvine Medical Center Psychiatry Residency Program in 2014 and joined the USC faculty. Dr. Cahn has been researching and publishing on the clinical and brain effects of mindfulness and meditative practices throughout his medical and scientific career as well as teaching mindfulness meditation in group settings for medical professionals as well as patients. He is currently affiliated with the USC Brain and Creativity Institute where he is conducting psychological and brain research in the domains of behavioral and psychological interventions including mindfulness and meditative practices in healthy populations dealing with everyday stressors as well as those with psychiatric illness including substance use disorders, depression, and anxiety.

Awards

  • Alliant University: Early Career Award for Contributions in Integrative Psychology, 2010
  • Council on Spiritual Practices: William James Award, 2004

Education and Training

  • UCSD, La Jolla, CA — MD — 2008 — Medicine
  • UCSD, La Jolla, CA — PhD — 2007 — Neuroscience

Research Keywords

  • mindfulness
  • meditation
  • psychophysiology
  • embodied cognition
  • self awareness
  • self narrative
  • well-being
  • depression
  • yoga
  • cognitive neuroscience
  • bipolar disorder
  • affective neuroscience
  • EEG
  • neurophenomenology
  • narrative-free awareness
  • psychedelic therapy

Publications

  • Brain-targeted epigenetic effects of two emerging psychoplastogens: ketamine & MDMA. Transl Psychiatry. 2026 Jul 11.. View in PubMed
  • Neural Responses to Affective Sentences Reveal Signatures of Depression. Transl Psychiatry. 2026 May 15; 16(1).. View in PubMed
  • Time-resolved EEG decoding reveals altered neural dynamics of affective semantic evaluation in depression and suicidality. Commun Biol. 2026 Apr 30; 9(1).. View in PubMed
  • Neural evidence of disrupted self-referential processing in suicidal depression. J Affect Disord. 2026 Aug 15; 407:121817.. View in PubMed
  • Deep learning characterizes depression and suicidal ideation in young adults from eye movements. NPJ Digit Med. 2026 Mar 28; 9(1).. View in PubMed
  • Effect of packaging with versus without candy-oriented marketing themes on the appeal and sensory attributes of flavoured e-cigarettes. Tob Control. 2026 01 08; 35(1):63-70.. View in PubMed
  • A Randomized Clinical Trial Reveals Effects of Mindfulness and Slow Breathing on Plasma Amyloid Beta Levels. Psychophysiology. 2025 12; 62(12):e70182.. View in PubMed
  • Decoding Neural Signatures of Semantic Evaluation in Depression and Suicidality. ArXiv. 2025 Jul 30.. View in PubMed
  • Daily mindfulness practice with and without slow breathing has opposing effects on plasma amyloid beta levels. medRxiv. 2025 Mar 11.. View in PubMed
  • ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Apr; 10(4):425-436.. View in PubMed