Tobias S. Ulmer, PhD

Dr. Ulmer received his PhD from the University of Oxford after completing his undergraduate work at the University of Zurich. After completing postdoctoral work at NIH, Dr. Ulmer establishes his research group at the University of Southern California (USC).

His research program centers on elucidating the molecular mechanism underlying physiological function and pathological dysfunction, respectively, of biological processes at atomic resolution. Specifically, the three-dimensional structure of proteins, their dynamics as well as protein-protein and protein-lipid interactions are determined. As a principal research tool, high-resolution, multidimensional solution-state nuclear magnetic resonance (NMR) spectroscopy is employed. His overarching interest is devoted to the structural biology of proteins that are either membrane embedded or membrane surface-bound.

Specifically, his laboratory focuses on understanding
(1) the structural basis of transmembrane signaling in cell surface receptors, and
(2) the mechanism of carnitine palmitoyltransferase 1 regulation.

• Mechanism of CD33 receptor signaling in Alzheimer disease
  NIH · R01AG072442 · May 15, 2021 – Apr 30, 2026 · Role: Principal Investigator
• Mechanism of CD33 receptor signaling in Alzheimer disease
  NIH · RF1AG072442 · May 15, 2021 – Apr 30, 2024 · Role: Principal Investigator
• Structural basis of CD33 receptor signaling in Alzheimer's disease
  NIH · R03AG063284 · Apr 1, 2019 – Jan 31, 2021 · Role: Principal Investigator
• Mechanisms of Integrin Receptor Transmembrane Signaling
  NIH · R01HL089726 · Apr 15, 2008 – Mar 31, 2014 · Role: Principal Investigator

• USC Researchers Find New Clues About Protein Linked To Parkinson's Disease

• Langen, Ralf
• An, Woojin
• Rissman, Robert
• Malmstadt, Noah
• Inaba, Kenji
• Siemer, Ansgar