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Aram Modrek

Assistant Professor of Radiation Oncology and Cancer Biology

DEI Champion for the Department of Radiation Oncology

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Email modrek@usc.edu
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Publications

  • Deconvolution of the tumor-educated platelet transcriptome reveals activated platelet and inflammatory cell transcript signatures JCI Insight. 2024 Aug 27; 9(19). . View in PubMed
  • Pulmonary Toxic Effects After Myeloablative Conditioning With Total Body Irradiation Delivered via Volumetric Modulated Arc Therapy With Fludarabine Pract Radiat Oncol. 2022 Nov-Dec; 12(6):e476-e480. . View in PubMed
  • Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma Cell Discov. 2022 Oct 06; 8(1):102. . View in PubMed
  • PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells Front Oncol. 2022; 12:941657. . View in PubMed
  • Insight into the public’s interest in tumour treating fields Br J Cancer. 2021 09; 125(6):901-903. . View in PubMed
  • Breaking Tradition to Bridge Bench and Bedside: Accelerating the MD-PhD-Residency Pathway Acad Med. 2021 04 01; 96(4):518-521. . View in PubMed
  • Design and implementation of a clinical decision support tool for primary palliative Care for Emergency Medicine (PRIM-ER) BMC Med Inform Decis Mak. 2020 Jan 28; 20(1):13. . View in PubMed
  • Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics Front Oncol. 2019; 9:417. . View in PubMed
  • Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma Sci Adv. 2018 10; 4(10):eaau5935. . View in PubMed
  • Modeling Glioma with Human Embryonic Stem Cell-Derived Neural Lineages Methods Mol Biol. 2018; 1741:227-237. . View in PubMed
  • Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2 Cell Rep. 2017 Oct 31; 21(5):1267-1280. . View in PubMed
  • Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells Oncotarget. 2017 Sep 12; 8(39):64932-64953. . View in PubMed
  • Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons Pathogens. 2017 Jun 08; 6(2). . View in PubMed
  • GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth Oncogenesis. 2016 Oct 24; 5(10):e263. . View in PubMed
  • Preplanning prediction of the left anterior descending artery maximum dose based on patient, dosimetric, and treatment planning parameters Adv Radiat Oncol. 2016 Oct-Dec; 1(4):373-381. . View in PubMed
  • Adult Primary Spinal Epidural Extraosseous Ewing’s Sarcoma: A Case Report and Review of the Literature Case Rep Neurol Med. 2016; 2016:1217428. . View in PubMed
  • Traumatic brain injury and subsequent glioblastoma development: Review of the literature and case reports Surg Neurol Int. 2016; 7:78. . View in PubMed
  • Radiation therapy improves survival in rectal small cell cancer – Analysis of Surveillance Epidemiology and End Results (SEER) data Radiat Oncol. 2015 Apr 24; 10:101. . View in PubMed
  • Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes J Biol Chem. 2014 Jun 13; 289(24):16727-35. . View in PubMed
  • Glioblastoma stem cells: Molecular characteristics and therapeutic implications World J Stem Cells. 2014 Apr 26; 6(2):230-8. . View in PubMed
  • Brain stem cells as the cell of origin in glioma World J Stem Cells. 2014 Jan 26; 6(1):43-52. . View in PubMed
  • Targeting tumor suppressor networks for cancer therapeutics Curr Drug Targets. 2014 Jan; 15(1):2-16. . View in PubMed
  • Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells PLoS One. 2014; 9(12):e116114. . View in PubMed
  • Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation J Biol Chem. 2011 Nov 04; 286(44):38783-38794. . View in PubMed

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