Ashley Margol
Director of the Pediatric Neuro-Oncology Program at CHLA
Contact
Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma Neuro Oncol. 2022 Nov 02; 24(11):1964-1975. . View in PubMed
Multi-institutional study of the frequency, genomic landscape and outcome of IDH-mutant glioma in paediatrics Neuro Oncol. 2022 May 23. . View in PubMed
Multi-institutional analysis of central nervous system germ cell tumors in patients with Down syndrome Pediatr Blood Cancer. 2022 10; 69(10):e29830. . View in PubMed
Primary Primitive Neuroectodermal Tumor of the Spine With t(11;22): Report of 3 Cases and Review of Literature J Pediatr Hematol Oncol. 2021 Oct 01; 43(7):e983-e986. . View in PubMed
Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma Pediatr Blood Cancer. 2021 10; 68(10):e29172. . View in PubMed
IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature Brain Pathol. 2021 07; 31(4):e12959. . View in PubMed
Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab037. . View in PubMed
Feasibility of Treating High Grade Gliomas in Children with Tumor-Treating Fields: A Case Series Cureus. 2020 Oct 05; 12(10):e10804. . View in PubMed
Primary diffuse leptomeningeal glioneuronal tumors of the central nervous system: Report of three cases and review of literature Pediatr Hematol Oncol. 2020 Apr; 37(3):248-258. . View in PubMed
A genome-wide association study on medulloblastoma J Neurooncol. 2020 Apr; 147(2):309-315. . View in PubMed
Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics Pediatr Blood Cancer. 2020 12; 67(12):e28516. . View in PubMed
SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors Neuro Oncol. 2020 06 09; 22(6):785-796. . View in PubMed
Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors Neuro Oncol. 2020 07 07; 22(7):944-954. . View in PubMed
Prognostic significance of molecular subgroups of medulloblastoma in young children receiving irradiation-sparing regimens J Neurooncol. 2019 Nov; 145(2):375-383. . View in PubMed
Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy Oncotarget. 2019 Jan 11; 10(4):551-557. . View in PubMed
Clinical and neuropsychological outcome of pediatric non-midline central nervous system germinoma treated with chemotherapy and reduced dose/volume irradiation: The Children's Hospital Los Angeles experience Pediatr Blood Cancer. 2019 12; 66(12):e27983. . View in PubMed
Pediatric Atypical Teratoid/Rhabdoid Tumors of the Brain: Identification of Metabolic Subgroups Using In Vivo 1H-MR Spectroscopy AJNR Am J Neuroradiol. 2019 05; 40(5):872-877. . View in PubMed
A comparative analysis of clinicopathological features and survival among early adolescents/young adults and children with low-grade glioma: a report from the Children's Oncology Group J Neurooncol. 2018 Dec; 140(3):575-582. . View in PubMed
Phase I trial of dasatinib, lenalidomide, and temozolomide in children with relapsed or refractory central nervous system tumors J Neurooncol. 2018 May; 138(1):199-207. . View in PubMed
Transmission of a TP53 germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner Cold Spring Harb Mol Case Stud. 2018 04; 4(2). . View in PubMed
Palliative Care Options for a Young Adult Patient with a Diffuse Intrinsic Pontine Glioma Cureus. 2017 Aug 18; 9(8):e1580. . View in PubMed
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome Acta Neuropathol. 2017 11; 134(5):705-714. . View in PubMed
Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach J Neurooncol. 2017 05; 133(1):119-128. . View in PubMed
Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy Pediatr Blood Cancer. 2016 09; 63(9):1527-34. . View in PubMed
Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy Neuro Oncol. 2016 Jan; 18(1):126-31. . View in PubMed
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas Sci Transl Med. 2016 11 23; 8(366):366ra161. . View in PubMed
Tumor-associated macrophages in SHH subgroup of medulloblastomas Clin Cancer Res. 2015 Mar 15; 21(6):1457-65. . View in PubMed
Pediatric brain tumor cell lines J Cell Biochem. 2015 Feb; 116(2):218-24. . View in PubMed
Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia Front Oncol. 2015; 5:191. . View in PubMed
Achieving target voriconazole concentrations more accurately in children and adolescents Antimicrob Agents Chemother. 2015; 59(6):3090-7. . View in PubMed
Pathology and diagnosis of SMARCB1-deficient tumors Cancer Genet. 2014 Sep; 207(9):358-64. . View in PubMed
PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas Clin Cancer Res. 2014 Feb 15; 20(4):827-36. . View in PubMed
Medulloblastoma expresses CD1d and can be targeted for immunotherapy with NKT cells Clin Immunol. 2013 Oct; 149(1):55-64. . View in PubMed
Pharmacokinetics and pharmacogenomics of once-daily raltegravir and atazanavir in healthy volunteers Antimicrob Agents Chemother. 2010 Nov; 54(11):4619-25. . View in PubMed