Ashley Margol, MD, MS

Associate Professor of Clinical Pediatrics

Director of the Pediatric Neuro-Oncology Program at CHLA

Image of Ashley Margol, MD, MS
Is this your profile? Click to edit

Overview

Ashley Margol, MD is originally from Jacksonville, Florida, where she and completed her undergraduate training at the University of Florida where she majored in zoology. She moved to Los Angeles to attend medical school at the Keck School of Medicine at the University of Southern California. She did her pediatric residency at Los Angeles County-University of Southern California after which she was honored to spend a fourth year as chief resident. Ashley recently completed her pediatric hematology-oncology fellowship at Children’s Hospital Los Angeles and is currently spending an additional year at Children’s Hospital Los Angeles training in pediatric neuro-oncology. Her research is examining the presence and role of inflammation in pediatric medulloblastoma, and she will complete her Masters of Science in Clinical, Biomedical and Translational Research this fall.

Publications

  • Metabolic and molecular correlates of medulloblastoma: Identification of molecular groups using in vivo 1H-MR spectroscopy. Neuro Oncol. 2026 Aug 01; 28(8):2041-2052.. View in PubMed
  • Understanding DMG: current treatment options and prospective solutions using nanoparticles. Drug Deliv Transl Res. 2026 Sep; 16(9):3231-3257.. View in PubMed
  • hTERT Expression, Regulation, and Prognostic Significance in Pediatric Medulloblastoma. bioRxiv. 2026 May 06.. View in PubMed
  • FOXR2-activated CNS neuroblastoma: Characterized by variable structural disruption of the FOXR2 regulatory region, recurrent copy number alterations, and elevated FOXR2 expression. Neurooncol Pediatr. 2026 Apr; 2(2):wuag014.. View in PubMed
  • Group 4 Medulloblastomas of Early Childhood Treated With High-Dose Chemotherapy- and Craniospinal Irradiation-Sparing Approach. Pediatr Blood Cancer. 2026 May; 73(5):e70181.. View in PubMed
  • A multi-institutional report of children with atypical teratoid rhabdoid tumor treated with intensive multimodal therapy. Neurooncol Pract. 2026 Aug; 13(4):807-815.. View in PubMed
  • Salvage therapies for first relapse of SHH medulloblastoma in early childhood. Neuro Oncol. 2025 Sep 17; 27(8):2158-2169.. View in PubMed
  • Multicellular tumor-stromal interactions recapitulate aspects of therapeutic response and human oncogenic signaling in a 3D disease model for H3K27M-altered DIPG. Oncogene. 2025 10; 44(39):3694-3712.. View in PubMed
  • Current advances in the management of atypical teratoid rhabdoid tumors (ATRT). Adv Cancer Res. 2025; 167:185-241.. View in PubMed
  • Measles Oncolytic Virus as an Immunotherapy for Recurrent/Refractory Pediatric Medulloblastoma and Atypical Teratoid/Rhabdoid Tumor: Results from PNOC005. Clin Cancer Res. 2025 Aug 14; 31(16):3463-3475.. View in PubMed