Bangyan L. Stiles, PhD

Professor

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Research Funding

  • The Role of ERRa in liver lipid dysfunction and pathology
    NIH · R01DK131492 · Dec 1, 2021 – Nov 30, 2025 · Role: Principal Investigator
  • Robust Inference in the Presence of Data Heterogeneity and Structured Missing Data
    NIH · R01LM013315 · Sep 1, 2019 – Aug 31, 2022 · Role: Co-Principal Investigator
  • The role of PTEN and AKT2 in the malignant transformation of liver progenitor cel
    NIH · R01CA154986 · Apr 1, 2013 – Mar 31, 2020 · Role: Principal Investigator
  • The mechanism of beta-cell regeneration
    NIH · R01DK084241 · Aug 5, 2010 – Jun 30, 2017 · Role: Principal Investigator
  • The Role of PTEN in B-cell regeneration through epithelial-mesenchymal transition
    NIH · R21DK075928 · Jul 1, 2007 – Jun 30, 2010 · Role: Principal Investigator

Publications

  • PTEN-AKT2 regulates mixed lineage liver cancer development and sensitizes cancer cells to TGFβ treatment. Oncogene. 2026 Aug 20.. View in PubMed
  • PTEN-AKT2 Regulates Mixed Lineage Liver Cancer Development and Sensitizes Cancer Cells to TGFβ Treatment. Res Sq. 2026 Jan 30.. View in PubMed
  • Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types. Discov Oncol. 2025 Dec 03; 17(1):36.. View in PubMed
  • A targeted liver cancer therapy independent of immune checkpoint block. Hepatology. 2026 Aug 01; 84(2):343-345.. View in PubMed
  • Characterizing Kupffer Cell Production of CD5 Antigen-Like and Its Function on Regulating Migration of Natural Killer T Cells. Am J Pathol. 2025 10; 195(10):1839-1853.. View in PubMed
  • Isoform specific regulation of osteopontin by AKT2 in hepatocytes and livers. Cell Signal. 2025 Aug; 132:111799.. View in PubMed
  • Proinflammatory macrophages release CXCL5 to regulate T cell function and limit effects of αPD-1 in steatosis-driven liver cancer. JHEP Rep. 2025 Jun; 7(6):101385.. View in PubMed
  • A snoRNA-tRNA modification network governs codon-biased cellular states. Proc Natl Acad Sci U S A. 2023 10 10; 120(41):e2312126120.. View in PubMed
  • Eicosanoids and other oxylipins in liver injury, inflammation and liver cancer development. Front Physiol. 2023; 14:1098467.. View in PubMed
  • Hepatic macrophage mediated immune response in liver steatosis driven carcinogenesis. Front Oncol. 2022; 12:958696.. View in PubMed