Bodour Salhia, PhD

Professor of Cancer Biology

Royce and Mary Trotter Chair in Cancer Research

Interim Chair of the Department of Cancer Biology

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Overview

Dr. Bodour Salhia is the Inaugural Interim Chair of the Department of Cancer Biology and the Royce & Mary Trotter Chair in Cancer Research at the Keck School of Medicine of USC. She also co-leads the Epigenetic Regulation in Cancer (ERC) Program and serves as the Inaugural Director of the Preclinical Models Shared Resource at the USC Norris Comprehensive Cancer Center. A recognized leader in academic medicine, she is a fellow of the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program.

A translational genomicist and epigenomicist, Dr. Salhia’s research integrates multi-omic technologies with functional and preclinical studies to address clinically urgent problems in cancer biology. Her work focuses on cfDNA methylation–based liquid biopsies for ovarian, breast, and colorectal cancer—efforts that have led to the development of OvaPrint™ for adnexal mass risk stratification and MammaTrace™ for minimal residual disease monitoring in breast cancer. She also leads the Eileen McGeever Breast Cancer Survivorship Program, advancing molecular approaches to recurrence risk prediction, and conducts research on the genomics and epigenomics of brain metastasis and degenerative eye disease. Her portfolio is supported by NIH, NSF, foundation, industry, and philanthropic funding. Motivated by the impact of liquid biopsy technologies on women’s health, she founded CpG Diagnostics, a USC spin-out dedicated to advancing cfDNA methylation diagnostics.

Dr. Salhia is deeply committed to community engagement and patient-centered research. She founded The Bench with Bedside Initiative, a direct-to-patient research platform designed to bring scientists to patients and patients into the scientific process. Her outreach spans work with the Arizona Myeloma Network, The Wellness Community, Susan G. Komen, and underserved communities including the Navajo Nation. She has also traveled across Africa to support cancer education for scientists and clinicians. Her leadership and advocacy have earned numerous honors, including recognition as one of the “20 Faces of Komen,” Phoenix Business Journal’s Top 40 Under 40, community service awards from the Arizona Myeloma Network, and the 2024 USC Academic Senate Distinguished Faculty Service Award.

Education and Training

  • University of Toronto, Toronto, Canada — PhD — 11/2006 — Cell and Molecular Biology
  • University of Toronto, Toronto, Canada — MHSC — 11/2001 — Cell and Molecular Biology
  • University of Toronto, Toronto, Canada — BS — 06/1998 — Biology, Psychology, Spanish

Publications

  • Single cell and spatial sequencing analysis of cancer associated fibroblasts in the brain metastasis tumor microenvironment. Commun Biol. 2026 Apr 01; 9(1).. View in PubMed
  • A comprehensive analysis of minimally differentially methylated regions common to pediatric and adult solid tumors. NPJ Precis Oncol. 2024 Jun 01; 8(1):125.. View in PubMed
  • Cancer-Associated Fibroblast Subpopulations With Diverse and Dynamic Roles in the Tumor Microenvironment. Mol Cancer Res. 2022 02; 20(2):183-192.. View in PubMed
  • The Establishment and Utilization of Patient Derived Xenograft Models of Central Nervous System Metastasis. J Vis Exp. 2021 05 07.. View in PubMed
  • Genome-wide DNA methylation analysis of KRAS mutant cell lines. Sci Rep. 2020 06 23; 10(1):10149.. View in PubMed
  • Isolation and characterization of patient-derived CNS metastasis-associated stromal cell lines. Oncogene. 2019 05; 38(21):4002-4014.. View in PubMed
  • Integrated genomic analysis of survival outliers in glioblastoma. Neuro Oncol. 2017 06 01; 19(6):833-844.. View in PubMed
  • Pathway Implications of Aberrant Global Methylation in Adrenocortical Cancer. PLoS One. 2016; 11(3):e0150629.. View in PubMed
  • Androgen receptor status is highly conserved during tumor progression of breast cancer. BMC Cancer. 2015 Nov 09; 15:872.. View in PubMed
  • Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer. Clin Epigenetics. 2015; 7:100.. View in PubMed