Charles Emerson Murry

Dr. Charles (Chuck) Murry received his bachelor’s degree in chemistry from the University of North Dakota, followed by MD-PhD training at Duke University, where he studied myocardial ischemia-reperfusion injury (heart attacks). He did residency training in Pathology at the University of Washington, followed by fellowship training in vascular biology and diagnostic cardiovascular pathology. He is currently chair of the Department of Stem Cell Biology and Regenerative Medicine, and director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Biology at USC. He has been proposed for appointment as the W.M. Keck Professor of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine of USC.

Murry’s research focuses on stem cell biology, with an emphasis on understanding differentiation of the human cardiovascular system and using these cells to study diseases and to regenerate damaged tissues. His group is a world leader in heart regeneration and is working toward a clinical trial using cardiomyocyte therapy.

In addition to running his research group, Dr. Murry was the director of the UW Institute for Stem Cell and Regenerative Medicine, and a professor in the departments of Laboratory Medicine & Pathology, Bioengineering, and Medicine/Cardiology at the University of Washington. He has served on many local, national and international committees, spoken widely about stem cells and cardiovascular medicine, and he has received numerous awards for teaching and scientific achievement. Dr. Murry previously served on the International Society for Stem Cell Research Board of Directors and currently serves on its Manufacturing, Clinical Translation, and Industry Committee.

In addition to his academic work, Murry has worked to promote commercialization of novel cardiovascular therapies. He cofounded BEAT Biotherapeutics, Sana Biotechnology, and most recently a Los Angeles-based startup called StemCardia.

• Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies Cell. 2024 Jun 07. . View in PubMed
• Long-term engraftment and maturation of autologous iPSC-derived cardiomyocytes in two rhesus macaques Cell Stem Cell. 2024 May 29. . View in PubMed
• Quantifying Microvascular Structure in Healthy and Infarcted Rat Hearts Using Optical Coherence Tomography Angiography IEEE Trans Med Imaging. 2024 Apr 03; PP. . View in PubMed
• Genetically Encoded XTEN-based Hydrogels with Tunable Viscoelasticity and Biodegradability for Injectable Cell Therapies Adv Sci (Weinh). 2024 Mar 13; e2301708. . View in PubMed
• Targeted CRISPR activation is functional in engineered human pluripotent stem cells but undergoes silencing after differentiation into cardiomyocytes and endothelium Cell Mol Life Sci. 2024 Feb 19; 81(1):95. . View in PubMed
• Multiplexed Functional Assessments of MYH7 Variants in Human Cardiomyocytes Circ Genom Precis Med. 2024 Feb 16; e004377. . View in PubMed
• Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy Cell Stem Cell. 2023 May 04; 30(5):741. . View in PubMed
• Cell based dATP delivery as a therapy for chronic heart failure bioRxiv. 2023 Apr 28. . View in PubMed
• Cardiomyocyte Apoptosis Is Associated with Contractile Dysfunction in Stem Cell Model of MYH7 E848G Hypertrophic Cardiomyopathy Int J Mol Sci. 2023 Mar 03; 24(5). . View in PubMed
• CRaTER enrichment for on-target gene-editing enables generation of variant libraries in hiPSCs bioRxiv. 2023 Jan 26. . View in PubMed
• Cardiomyocyte apoptosis contributes to contractile dysfunction in stem cell model of MYH7 E848G hypertrophic cardiomyopathy bioRxiv. 2023 Jan 25. . View in PubMed
• Stacking thick perfusable human microvascular grafts enables dense vascularity and rapid integration into infarcted rat hearts Biomaterials. 2023 10; 301:122250. . View in PubMed
• Graft-host coupling changes can lead to engraftment arrhythmia: a computational study J Physiol. 2023 07; 601(13):2733-2749. . View in PubMed
• CRaTER enrichment for on-target gene editing enables generation of variant libraries in hiPSCs J Mol Cell Cardiol. 2023 06; 179:60-71. . View in PubMed
• dATP elevation induces myocardial metabolic remodeling to support improved cardiac function J Mol Cell Cardiol. 2023 02; 175:1-12. . View in PubMed
• Lessons learnt, and still to learn, in first in human stem cell trials Stem Cell Reports. 2023 08 08; 18(8):1599-1609. . View in PubMed
• Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapyCell Stem Cell. 2023 04 06; 30(4):396-414. e9. . View in PubMed
• Epicardially secreted fibronectin drives cardiomyocyte maturation in 3D-engineered heart tissues Stem Cell Reports. 2023 04 11; 18(4):936-951. . View in PubMed
• Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation Stem Cell Reports. 2023 01 10; 18(1):159-174. . View in PubMed
• Engineered tissue vascularization and engraftment depends on host model Sci Rep. 2023 02 03; 13(1):1973. . View in PubMed
• Amino acid primed mTOR activity is essential for heart regeneration iScience. 2022 Jan 21; 25(1):103574. . View in PubMed
• Flexing Their Muscles: Maturation of Stem Cell-Derived Cardiomyocytes on Elastomeric Substrates to Enhance Cardiac Repair Circulation. 2022 05 03; 145(18):1427-1430. . View in PubMed
• Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations Light Sci Appl. 2021 Nov 24; 10(1):237. . View in PubMed
• Quantitative Analyses of the Left Ventricle Volume and Cardiac Function in Normal and Infarcted Yucatan Minipigs J Imaging. 2021 Jul 01; 7(7). . View in PubMed
• Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems Biomaterials. 2021 05; 272:120764. . View in PubMed
• Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo Circulation. 2021 04 20; 143(16):1635-1638. . View in PubMed
• Rescuing human fetal tissue research in the United States: A call for additional regulatory reform Stem Cell Reports. 2021 12 14; 16(12):2839-2843. . View in PubMed
• Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes Stem Cell Reports. 2021 10 12; 16(10):2473-2487. . View in PubMed
• Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies Nat Commun. 2021 11 03; 12(1):6324. . View in PubMed
• SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function Stem Cell Reports. 2021 03 09; 16(3):478-492. . View in PubMed
• Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations JCI Insight. 2021 12 22; 6(24). . View in PubMed
• High-resolution 3D fluorescent imaging of intact tissues Int J Cardiol Cardiovasc Dis. 2021; 1(1):1-14. . View in PubMed
• Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment Cell Rep. 2021 05 04; 35(5):109088. . View in PubMed
• Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury Mol Ther Methods Clin Dev. 2020 Jun 12; 17:986-998. . View in PubMed
• Stem cells and the heart-the road ahead Science. 2020 Feb 21; 367(6480):854-855. . View in PubMed
• Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine Nat Rev Cardiol. 2020 06; 17(6):341-359. . View in PubMed
• Engineering anisotropic 3D tubular tissues with flexible thermoresponsive nanofabricated substrates Biomaterials. 2020 05; 240:119856. . View in PubMed
• Cell Therapy Strategies With No Safety Concerns and Demonstrated Benefits Warrant Study – Reply Circ J. 2020 10 23; 84(11):2122. . View in PubMed
• Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes Nat Commun. 2020 05 08; 11(1):2387. . View in PubMed
• Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells Cardiovasc Res. 2020 02 01; 116(2):368-382. . View in PubMed
• A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives Stem Cell Reports. 2020 07 14; 15(1):226-241. . View in PubMed
• Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts PLoS One. 2020; 15(1):e0227780. . View in PubMed
• NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells Nano Lett. 2020 03 11; 20(3):1561-1570. . View in PubMed
• Learn from Your Elders: Developmental Biology Lessons to Guide Maturation of Stem Cell-Derived Cardiomyocytes Pediatr Cardiol. 2019 Oct; 40(7):1367-1387. . View in PubMed
• Substrate Stiffness, Cell Anisotropy, and Cell-Cell Contact Contribute to Enhanced Structural and Calcium Handling Properties of Human Embryonic Stem Cell-Derived Cardiomyocytes ACS Biomater Sci Eng. 2019 Aug 12; 5(8):3876-3888. . View in PubMed
• Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration Nat Biotechnol. 2019 08; 37(8):895-906. . View in PubMed
• Regenerating the field of cardiovascular cell therapy Nat Biotechnol. 2019 03; 37(3):232-237. . View in PubMed
• Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts Nat Commun. 2019 02 04; 10(1):584. . View in PubMed
• The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy Nat Commun. 2019 05 22; 10(1):2267. . View in PubMed
• Cronos Titin Is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function Circulation. 2019 11 12; 140(20):1647-1660. . View in PubMed
• Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy J Cell Biol. 2019 09 02; 218(9):2919-2944. . View in PubMed
• Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells Stem Cell Reports. 2019 10 08; 13(4):657-668. . View in PubMed
• Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory Nat Commun. 2019 04 04; 10(1):1538. . View in PubMed
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• Function Follows Form – A Review of Cardiac Cell Therapy Circ J. 2019 11 25; 83(12):2399-2412. . View in PubMed
• Lost in the fire Science. 2019 04 12; 364(6436):123-124. . View in PubMed
• TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes Nat Commun. 2019 10 11; 10(1):4671. . View in PubMed
• Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells JACC Basic Transl Sci. 2018 Dec; 3(6):728-740. . View in PubMed
• Human Organ-Specific Endothelial Cell Heterogeneity iScience. 2018 Jun 29; 4:20-35. . View in PubMed
• The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards? Stem Cell Reports. 2018 May 08; 10(5):1429-1431.. View in PubMed
• ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells iScience. 2018 Apr 27; 2:88-100. . View in PubMed
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• Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates Nat Biotechnol. 2018 08; 36(7):597-605. . View in PubMed
• Regulation of skeletal myotube formation and alignment by nanotopographically controlled cell-secreted extracellular matrix J Biomed Mater Res A. 2018 06; 106(6):1543-1551. . View in PubMed
• Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues J Mol Cell Cardiol. 2018 05; 118:147-158. . View in PubMed
• Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal Cell Cycle. 2018; 17(5):535-549. . View in PubMed
• Human Pluripotent Stem Cell-Derived Engineered Tissues: Clinical Considerations Cell Stem Cell. 2018 03 01; 22(3):294-297. . View in PubMed
• Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart Circulation. 2018 12 18; 138(25):2931-2939. . View in PubMed
• Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte MaturationCell Stem Cell. 2018 10 04; 23(4):586-598. e8. . View in PubMed
• Erratum: Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates Nat Biotechnol. 2018 09 06; 36(9):899. . View in PubMed
• Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart Circulation. 2018 12 18; 138(25):2960-2962. . View in PubMed
• Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering Chem Commun (Camb). 2017 Jun 29; 53(53):7412-7415. . View in PubMed
• Sustained miRNA release regenerates the heart Nat Biomed Eng. 2017 12; 1(12):931-933. . View in PubMed
• Cardiomyocyte Regeneration: A Consensus Statement Circulation. 2017 08 15; 136(7):680-686. . View in PubMed
• In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts Stem Cell Reports. 2017 02 14; 8(2):278-289. . View in PubMed
• Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis Cell Rep. 2017 08 15; 20(7):1597-1608. . View in PubMed
• One Stride Forward: Maturation and Scalable Production of Engineered Human Myocardium Circulation. 2017 05 09; 135(19):1848-1850. . View in PubMed
• Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells Nat Protoc. 2017 Jan; 12(1):15-31. . View in PubMed
• Translation of Cardiac Myosin Activation with 2-deoxy-ATP to Treat Heart Failure via an Experimental Ribonucleotide Reductase-Based Gene Therapy JACC Basic Transl Sci. 2016 Dec; 1(7):666-679. . View in PubMed
• Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue Circulation. 2016 Nov 15; 134(20):1557-1567. . View in PubMed
• New ISSCR guidelines: clinical translation of stem cell research Lancet. 2016 May 14; 387(10032):1979-81. . View in PubMed
• SCIENTIFIC COMMUNITYConfronting stem cell hype. Science. 2016 May 13; 352(6287):776-7. . View in PubMed
• Imprecision Medicine: A One-Size-Fits-Many Approach for Muscle Dystrophy Cell Stem Cell. 2016 Apr 07; 18(4):423-4. . View in PubMed
• Stromal Cells in Dense Collagen Promote Cardiomyocyte and Microvascular Patterning in Engineered Human Heart Tissue Tissue Eng Part A. 2016 Apr; 22(7-8):633-44. . View in PubMed
• AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility Mol Ther. 2016 Feb; 24(2):240-250. . View in PubMed
• Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/ß-catenin signaling Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4):1002-7. . View in PubMed
• Prosurvival Factors Improve Functional Engraftment of Myogenically Converted Dermal Cells into Dystrophic Skeletal Muscle Stem Cells Dev. 2016 10; 25(20):1559-1569. . View in PubMed
• Policy: Global standards for stem-cell research Nature. 2016 05 19; 533(7603):311-3. . View in PubMed
• Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Stem Cell Reports. 2016 06 14; 6(6):885-896. . View in PubMed
• Depth-resolved 3D visualization of coronary microvasculature with optical microangiography Phys Med Biol. 2016 11 07; 61(21):7536-7550. . View in PubMed
• Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells ACS Appl Mater Interfaces. 2016 08 31; 8(34):21923-32. . View in PubMed
• Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development Genome Biol. 2016 12 19; 17(1):263. . View in PubMed
• Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines Stem Cell Reports. 2016 06 14; 6(6):787-797. . View in PubMed
• Distilling complexity to advance cardiac tissue engineering Sci Transl Med. 2016 06 08; 8(342):342ps13. . View in PubMed
• Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair Stem Cell Reports. 2015 Nov 10; 5(5):753-762. . View in PubMed
• The advancement of human pluripotent stem cell-derived therapies into the clinic Development. 2015 Oct 15; 142(20):3614. . View in PubMed
• Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes Cell Rep. 2015 Sep 29; 12(12):1960-7. . View in PubMed
• The advancement of human pluripotent stem cell-derived therapies into the clinic Development. 2015 Sep 15; 142(18):3077-84. . View in PubMed
• Inhibition of ß-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes Development. 2015 Sep 15; 142(18):3198-209. . View in PubMed
• Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure Eur J Heart Fail. 2015 Aug; 17(8):772-81. . View in PubMed
• Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors Stem Cells. 2015 Jul; 33(7):2148-57. . View in PubMed
• Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development Genome Biol. 2015 Jun 16; 16:126. . View in PubMed
• Response to cardiac regeneration validated Nat Biotechnol. 2015 Jun; 33(6):587. . View in PubMed
• Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells Nat Biotechnol. 2015 Jun; 33(6):646-55. . View in PubMed
• Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes Proc Natl Acad Sci U S A. 2015 May 26; 112(21):E2785-94. . View in PubMed
• The winding road to regenerating the human heart Cardiovasc Pathol. 2015 May-Jun; 24(3):133-40. . View in PubMed
• Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts PLoS One. 2015; 10(7):e0131446. . View in PubMed
• Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettes PLoS One. 2015; 10(5):e0126259. . View in PubMed
• Cardiac regeneration using pluripotent stem cells–progression to large animal models Stem Cell Res. 2014 Nov; 13(3 Pt B):654-65. . View in PubMed
• Letter by Murry et al regarding article, “Embryonic stem cell-derived cardiac myocytes are not ready for human trials” Circ Res. 2014 Oct 24; 115(10):e28-9. . View in PubMed
• Clinical imaging in regenerative medicine Nat Biotechnol. 2014 Aug; 32(8):804-18. . View in PubMed
• Heart regeneration with engineered myocardial tissue Annu Rev Biomed Eng. 2014 Jul 11; 16:1-28. . View in PubMed
• Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts J Mol Cell Cardiol. 2014 Jul; 72:219-27. . View in PubMed
• Magnetic Resonance Imaging Tracking of Graft Survival in the Infarcted Heart: Iron Oxide Particles Versus Ferritin Overexpression Approach J Cardiovasc Pharmacol Ther. 2014 Jul; 19(4):358-367. . View in PubMed
• Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells J Mol Cell Cardiol. 2014 Jul; 72:296-304. . View in PubMed
• Cell-based delivery of dATP via gap junctions enhances cardiac contractility J Mol Cell Cardiol. 2014 Jul; 72:350-9. . View in PubMed
• Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts Nature. 2014 Jun 12; 510(7504):273-7. . View in PubMed
• Capillary force lithography for cardiac tissue engineering J Vis Exp. 2014 Jun 10; (88). . View in PubMed
• Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies Nat Med. 2014 Jun; 20(6):616-23. . View in PubMed
• Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control ACS Nano. 2014 May 27; 8(5):4430-9. . View in PubMed
• Proliferation at the heart of preadolescence Cell. 2014 May 08; 157(4):765-7. . View in PubMed
• Measuring the contractile forces of human induced pluripotent stem cell-derived cardiomyocytes with arrays of microposts J Biomech Eng. 2014 May; 136(5):051005. . View in PubMed
• Vascular Perfusion of Implanted Human Engineered Cardiac Tissue Proc IEEE Annu Northeast Bioeng Conf. 2014 Apr; 2014. . View in PubMed
• Engineered biomaterials control differentiation and proliferation of human-embryonic-stem-cell-derived cardiomyocytes via timed Notch activation Stem Cell Reports. 2014 Mar 11; 2(3):271-81. . View in PubMed
• Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery Stem Cell Res. 2014 Mar; 12(2):467-80. . View in PubMed
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• Proangiogenic microtemplated fibrin scaffolds containing aprotinin promote improved wound healing responses Angiogenesis. 2014 Jan; 17(1):195-205. . View in PubMed
• Improving survival and efficacy of pluripotent stem cell-derived cardiac grafts J Cell Mol Med. 2013 Nov; 17(11):1355-62. . View in PubMed
• SLIT3-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo J Mol Cell Cardiol. 2013 Nov; 64:124-31. . View in PubMed
• Trends in cardiovascular engineering: organizing the human heart Trends Cardiovasc Med. 2013 Nov; 23(8):282-6. . View in PubMed
• An improved cryosection method for polyethylene glycol hydrogels used in tissue engineering Tissue Eng Part C Methods. 2013 Oct; 19(10):794-801. . View in PubMed
• Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development Development. 2013 Sep; 140(18):3799-808. . View in PubMed
• Developmental fate and cellular maturity encoded in human regulatory DNA landscapes Cell. 2013 Aug 15; 154(4):888-903. . View in PubMed
• Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart Stem Cells Dev. 2013 Jul 01; 22(13):1932-43. . View in PubMed
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• Cell therapy enhances function of remote non-infarcted myocardium J Mol Cell Cardiol. 2009 Nov; 47(5):603-13. . View in PubMed
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• Scaffold-free human cardiac tissue patch created from embryonic stem cells Tissue Eng Part A. 2009 Jun; 15(6):1211-22. . View in PubMed
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• Get with the (re)program: cardiovascular potential of skin-derived induced pluripotent stem cells Circulation. 2008 Jul 29; 118(5):472-5. . View in PubMed
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• Absence of regeneration in the MRL/MpJ mouse heart following infarction or cryoinjury Cardiovasc Pathol. 2008 Jan-Feb; 17(1):6-13. . View in PubMed
• Fibroblast growth factor-2 regulates myocardial infarct repair: effects on cell proliferation, scar contraction, and ventricular function Am J Pathol. 2007 Nov; 171(5):1431-40. . View in PubMed
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• Kloner, Robert
• McCain, Megan