Charles Emerson Murry

Professor of Stem Cell Biology and Regenerative Medicine, Pathology, Medicine, and Biomedical Engineering

Chair of the Department of Stem Cell Biology and Regenerative Medicine

Robert A. Day Professorship of Medical Innovation

Director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research

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Overview

Dr. Charles (Chuck) Murry received his bachelor’s degree in chemistry from the University of North Dakota, followed by MD-PhD training at Duke University, where he studied myocardial ischemia-reperfusion injury (heart attacks). He did residency training in Pathology at the University of Washington, followed by fellowship training in vascular biology and diagnostic cardiovascular pathology. He is currently chair of the Department of Stem Cell Biology and Regenerative Medicine, and director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Biology at USC. He has been proposed for appointment as the W.M. Keck Professor of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine of USC.Murry’s research focuses on stem cell biology, with an emphasis on understanding differentiation of the human cardiovascular system and using these cells to study diseases and to regenerate damaged tissues. His group is a world leader in heart regeneration and is working toward a clinical trial using cardiomyocyte therapy. In addition to running his research group, Dr. Murry was the director of the UW Institute for Stem Cell and Regenerative Medicine, and a professor in the departments of Laboratory Medicine & Pathology, Bioengineering, and Medicine/Cardiology at the University of Washington. He has served on many local, national and international committees, spoken widely about stem cells and cardiovascular medicine, and he has received numerous awards for teaching and scientific achievement. Dr. Murry previously served on the International Society for Stem Cell Research Board of Directors and currently serves on its Manufacturing, Clinical Translation, and Industry Committee.In addition to his academic work, Murry has worked to promote commercialization of novel cardiovascular therapies. He cofounded BEAT Biotherapeutics, Sana Biotechnology, and most recently a Los Angeles-based startup called StemCardia.

Publications

  • Cell-type specific allelic dampening of sex-linked genes in sex chromosome aneuploidy. bioRxiv. 2026 Apr 21.. View in PubMed
  • Reliable Identification of Cardiac Maturation Markers Using Robust and Flexible Label-Free Proteomic Quantitation by Spectral Counting on Relatively Abundant Proteins. J Proteome Res. 2026 Apr 03; 25(4):2150-2159.. View in PubMed
  • Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease. JCI Insight. 2026 Feb 23; 11(4).. View in PubMed
  • Functional interrogation of contextually correct MYH7 variants using CRaTER-flox gene editing and contractility profiling. J Clin Invest. 2026 Jan 16; 136(2).. View in PubMed
  • Nanopatterned Cell Sheet Assembly of Biomimetic Cardiac Laminae for Modeling Structure-Function Relationships. Biomater Res. 2026; 30:0339.. View in PubMed
  • Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. Cell Stem Cell. 2025 Oct 02; 32(10):1614-1633.e13.. View in PubMed
  • Early awakenings: new insights into graft-host coupling in cardiac cell therapy. Cardiovasc Res. 2025 Sep 29; 121(11):1638-1639.. View in PubMed
  • Bioengineered Human Cardiac Ventricular Model with Transmural Helical Remodeling. Adv Healthc Mater. 2025 Aug; 14(22):e2502005.. View in PubMed
  • WITHDRAWN: Cell based dATP delivery as a therapy for chronic heart failure. bioRxiv. 2025 May 27.. View in PubMed
  • Retraction notice to “dATP elevation induces myocardial metabolic remodeling to support improved cardiac function” [Journal of Molecular and Cellular Cardiology 175 (2022) 1-12]. J Mol Cell Cardiol. 2024 12; 197:150.. View in PubMed

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