Christopher J.L. Newth, MD

Professor of Pediatrics and Anesthesiology

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Publications

  • Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children Crit Care Med. 2023 Dec 01; 51(12):1766-1776. . View in PubMed
  • Determining an Optimal Oxygen Saturation Target Range Based on Neonatal Maturity: Demonstration of a Decision Tree Analytic Diagnostics (Basel). 2023 Oct 26; 13(21). . View in PubMed
  • Acute Disorders of Consciousness in Pediatric Severe Sepsis and Organ Failure: Secondary Analysis of the Multicenter Phenotyping Sepsis-Induced Multiple Organ Failure Study Pediatr Crit Care Med. 2023 Oct 01; 24(10):840-848. . View in PubMed
  • Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest JAMA Netw Open. 2023 Jun 01; 6(6):e2320713. . View in PubMed
  • Effort and work-of-breathing parameters strongly correlate with increased resistance in an animal model Pediatr Res. 2023 09; 94(3):944-949. . View in PubMed
  • Operational Definitions Related to Pediatric Ventilator Liberation Chest. 2023 05; 163(5):1130-1143. . View in PubMed
  • Anticoagulation practices associated with bleeding and thrombosis in pediatric extracorporeal membrane oxygenation; a multi-center secondary analysis Perfusion. 2023 03; 38(2):363-372. . View in PubMed
  • A 30-Minute Spontaneous Breathing Trial Misses Many Children Who Go On to Fail a 120-Minute Spontaneous Breathing Trial Chest. 2023 01; 163(1):115-127. . View in PubMed
  • Leveraging Clinical Informatics and Data Science to Improve Care and Facilitate Research in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference Pediatr Crit Care Med. 2023 02 01; 24(12 Suppl 2):S1-S11. . View in PubMed
  • Estimation of inspiratory effort using airway occlusion maneuvers in ventilated children: a secondary analysis of an ongoing randomized trial testing a lung and diaphragm protective ventilation strategy Crit Care. 2023 11 29; 27(1):466. . View in PubMed
  • The end-tidal alveolar dead space fraction for risk stratification during the first week of invasive mechanical ventilation: an observational cohort study Crit Care. 2023 02 09; 27(1):54. . View in PubMed
  • Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Document Am J Respir Crit Care Med. 2023 01 01; 207(1):17-28. . View in PubMed
  • Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2) Pediatr Crit Care Med. 2023 02 01; 24(2):143-168. . View in PubMed
  • High-Flow Nasal Cannula Reduces Effort of Breathing But Not Consistently via Positive End-Expiratory Pressure Chest. 2022 Oct; 162(4):861-871. . View in PubMed
  • Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A PALISI Network Document Am J Respir Crit Care Med. 2022 Aug 15. . View in PubMed
  • Development of a Pleural Pressure Catheter via Continuous Fiberoptic Esophageal Pressure Measurements Annu Int Conf IEEE Eng Med Biol Soc. 2022 07; 2022:3269-3272. . View in PubMed
  • Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis J Clin Immunol. 2022 02; 42(2):350-364. . View in PubMed
  • Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study Crit Care. 2022 01 03; 26(1):2. . View in PubMed
  • Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy J Am Med Inform Assoc. 2022 12 13; 30(1):178-194. . View in PubMed
  • Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest JAMA Netw Open. 2022 09 01; 5(9):e2230518. . View in PubMed
  • The Association of Early Corticosteroid Therapy With Clinical and Health-Related Quality of Life Outcomes in Children With Septic Shock Pediatr Crit Care Med. 2022 09 01; 23(9):687-697. . View in PubMed
  • Clinical Challenges in Pediatric Ventilation Liberation: A Meta-Narrative Review Pediatr Crit Care Med. 2022 12 01; 23(12):999-1008. . View in PubMed
  • Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock Pediatr Crit Care Med. 2022 08 01; 23(8):635-645. . View in PubMed
  • Health Resource Use in Survivors of Pediatric Septic Shock in the United States Pediatr Crit Care Med. 2022 06 01; 23(6):e277-e288. . View in PubMed
  • Outcomes Associated With Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study Shock. 2022 01 01; 57(1):88-94. . View in PubMed
  • Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels Pediatr Crit Care Med. 2022 12 01; 23(12):968-979. . View in PubMed
  • Normalization to Predicted Body Weight May Underestimate Mechanical Energy in Pediatric Acute Respiratory Distress Syndrome Am J Respir Crit Care Med. 2022 06 01; 205(11):1360-1363. . View in PubMed
  • Continuous noninvasive blood gas estimation in critically ill pediatric patients with respiratory failure Sci Rep. 2022 06 14; 12(1):9853. . View in PubMed
  • A New Trick for an Old Dog: L-Epinephrine Delivered Continuously in the Vapor Phase Crit Care Explor. 2021 Oct; 3(10):e0541. . View in PubMed
  • Declining Procedures in Pediatric Critical Care Medicine Using a National Database Crit Care Explor. 2021 Mar; 3(3):e0359. . View in PubMed
  • The Association Between Ventilatory Ratio and Mortality in Children and Young Adults Respir Care. 2021 Feb; 66(2):205-212. . View in PubMed
  • Frequency and Risk Factors for Reverse Triggering in Pediatric Acute Respiratory Distress Syndrome during Synchronized Intermittent Mandatory Ventilation Ann Am Thorac Soc. 2021 05; 18(5):820-829. . View in PubMed
  • Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock Front Pediatr. 2021; 9:675374. . View in PubMed
  • Subglottic Post-Extubation Upper Airway Obstruction Is Associated With Long-Term Airway Morbidity in Children Pediatr Crit Care Med. 2021 10 01; 22(10):e502-e512. . View in PubMed
  • Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities Pediatr Crit Care Med. 2021 05 01; 22(5):e302-e313. . View in PubMed
  • Adherence to Lung-Protective Ventilation Principles in Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study Crit Care Med. 2021 10 01; 49(10):1779-1789. . View in PubMed
  • Machine Learning to Predict Cardiac Death Within 1 Hour After Terminal Extubation Pediatr Crit Care Med. 2021 02 01; 22(2):161-171. . View in PubMed
  • Machine learning model for early prediction of acute kidney injury (AKI) in pediatric critical care Crit Care. 2021 08 10; 25(1):288. . View in PubMed
  • Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions J Am Med Inform Assoc. 2021 06 12; 28(6):1330-1344. . View in PubMed
  • Direction and Magnitude of Change in Plateau From Peak Pressure During Inspiratory Holds Can Identify the Degree of Spontaneous Effort and Elastic Workload in Ventilated Patients Crit Care Med. 2021 03 01; 49(3):517-526. . View in PubMed
  • Risk Factors for Mortality in Refractory Pediatric Septic Shock Supported with Extracorporeal Life Support ASAIO J. 2020 Nov/Dec; 66(10):1152-1160. . View in PubMed
  • Ventilator Liberation in the Pediatric ICU Respir Care. 2020 Oct; 65(10):1601-1610. . View in PubMed
  • To Change Is to Improve Respir Care. 2020 12; 65(12):1933-1935. . View in PubMed
  • Real-Time Effort Driven Ventilator Management: A Pilot Study Pediatr Crit Care Med. 2020 11; 21(11):933-940. . View in PubMed
  • Underweight is the highest PICU mortality risk factor among all other weight categories J Pediatr. 2020 11; 226:309-313. . View in PubMed
  • Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock Pediatr Crit Care Med. 2020 10; 21(10):869-878. . View in PubMed
  • High Breath-by-Breath Variability Is Associated With Extubation Failure in Children Crit Care Med. 2020 08; 48(8):1165-1174. . View in PubMed
  • Association between time of day and CPR quality as measured by CPR hemodynamics during pediatric in-hospital CPR Resuscitation. 2020 08; 153:209-216. . View in PubMed
  • Spontaneous Breathing and Imposed Work During Pediatric Mechanical Ventilation: A Bench Study Pediatr Crit Care Med. 2020 07; 21(7):e449-e455. . View in PubMed
  • Survival and Hemodynamics During Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest Crit Care Med. 2020 06; 48(6):881-889. . View in PubMed
  • Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock Crit Care Med. 2020 03; 48(3):329-337. . View in PubMed
  • Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock Crit Care Med. 2020 03; 48(3):319-328. . View in PubMed
  • Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Pediatr Crit Care Med. 2020 02; 21(2):186-195. . View in PubMed
  • Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children Intensive Care Med. 2020 02; 46(Suppl 1):1-9. . View in PubMed
  • Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation Pediatr Crit Care Med. 2020 02; 21(2):178-185. . View in PubMed
  • The role of computer-based clinical decision support systems to deliver protective mechanical ventilation Curr Opin Crit Care. 2020 02; 26(1):73-81. . View in PubMed
  • Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children Intensive Care Med. 2020 02; 46(Suppl 1):10-67. . View in PubMed
  • Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Pediatr Crit Care Med. 2020 02; 21(2):e52-e106. . View in PubMed
  • A Phase II randomized controlled trial for lung and diaphragm protective ventilation (Real-time Effort Driven VENTilator management) Contemp Clin Trials. 2020 01; 88:105893. . View in PubMed
  • Thresholds for oximetry alarms and target range in the NICU: an observational assessment based on likely oxygen tension and maturity BMC Pediatr. 2020 06 27; 20(1):317. . View in PubMed
  • Hypoxemic and hyperoxemic likelihood in pulse oximetry ranges: NICU observational study Arch Dis Child Fetal Neonatal Ed. 2019 May; 104(3):F274-F279. . View in PubMed
  • Accuracy of Transcutaneous Carbon Dioxide Levels in Comparison to Arterial Carbon Dioxide Levels in Critically Ill Children Respir Care. 2019 Feb; 64(2):201-208. . View in PubMed
  • A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure Pediatr Crit Care Med. 2019 12; 20(12):1137-1146. . View in PubMed
  • Survival and Cardiopulmonary Resuscitation Hemodynamics Following Cardiac Arrest in Children With Surgical Compared to Medical Heart Disease Pediatr Crit Care Med. 2019 12; 20(12):1126-1136. . View in PubMed
  • Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes Crit Care Med. 2019 11; 47(11):1627-1636. . View in PubMed
  • Evaluating the Practice of Repositioning Endotracheal Tubes in Neonates and Children Based on Radiographic Location Pediatr Crit Care Med. 2019 11; 20(11):1057-1060. . View in PubMed
  • Functional outcomes among survivors of pediatric in-hospital cardiac arrest are associated with baseline neurologic and functional status, but not with diastolic blood pressure during CPR Resuscitation. 2019 10; 143:57-65. . View in PubMed
  • The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest Resuscitation. 2019 08; 141:88-95. . View in PubMed
  • Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic Shock: A Retrospective Cohort StudyJ Pediatr. 2019 07; 210:178-183. e2. . View in PubMed
  • Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children Crit Care Med. 2019 05; 47(5):706-714. . View in PubMed
  • Development of the Pediatric Extracorporeal Membrane Oxygenation Prediction Model for Risk-Adjusting Mortality Pediatr Crit Care Med. 2019 05; 20(5):426-434. . View in PubMed
  • Characteristics and Outcomes of Critical Illness in Children With Feeding and Respiratory Technology Dependence Pediatr Crit Care Med. 2019 05; 20(5):417-425. . View in PubMed
  • Change in functional status among children treated in the intensive care unit after injury J Trauma Acute Care Surg. 2019 05; 86(5):810-816. . View in PubMed
  • Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study Lancet Respir Med. 2019 02; 7(2):115-128. . View in PubMed
  • Minimal Change in Cardiac Index With Increasing PEEP in Pediatric Acute Respiratory Distress Syndrome Front Pediatr. 2019; 7:9. . View in PubMed
  • PICU Autopsies: Rates, Patient Characteristics, and the Role of the Medical Examiner Pediatr Crit Care Med. 2018 Dec; 19(12):1137-1145. . View in PubMed
  • Hemolysis During Pediatric Extracorporeal Membrane Oxygenation: Associations With Circuitry, Complications, and Mortality Pediatr Crit Care Med. 2018 Nov; 19(11):1067-1076. . View in PubMed
  • Measurements Obtained From Esophageal Balloon Catheters Are Affected by the Esophageal Balloon Filling Volume in Children With ARDS Respir Care. 2018 Feb; 63(2):177-186. . View in PubMed
  • Predicting cardiac arrests in pediatric intensive care units Resuscitation. 2018 12; 133:25-32. . View in PubMed
  • The authors reply Crit Care Med. 2018 12; 46(12):e1231. . View in PubMed
  • End-tidal carbon dioxide during pediatric in-hospital cardiopulmonary resuscitation Resuscitation. 2018 12; 133:173-179. . View in PubMed
  • The Association Between Inhaled Nitric Oxide Treatment and ICU Mortality and 28-Day Ventilator-Free Days in Pediatric Acute Respiratory Distress Syndrome Crit Care Med. 2018 11; 46(11):1803-1810. . View in PubMed
  • Chest compression rates and pediatric in-hospital cardiac arrest survival outcomes Resuscitation. 2018 09; 130:159-166. . View in PubMed
  • Acquired infection during neonatal and pediatric extracorporeal membrane oxygenation Perfusion. 2018 09; 33(6):472-482. . View in PubMed
  • Response Chest. 2018 09; 154(3):729-730. . View in PubMed
  • Does Size Matter When Calculating the “Correct” Tidal Volume for Pediatric Mechanical Ventilation? : A Hypothesis Based on FVC. Chest. 2018 07; 154(1):77-83.. View in PubMed
  • RBC Transfusion Practice in Pediatric Extracorporeal Membrane Oxygenation Support Crit Care Med. 2018 06; 46(6):e552-e559. . View in PubMed
  • Paediatric in-hospital cardiac arrest: Factors associated with survival and neurobehavioural outcome one year later Resuscitation. 2018 03; 124:96-105. . View in PubMed
  • PICU Length of Stay: Factors Associated With Bed Utilization and Development of a Benchmarking Model Pediatr Crit Care Med. 2018 03; 19(3):196-203. . View in PubMed
  • Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors Pediatr Crit Care Med. 2018 03; 19(3):245-253. . View in PubMed
  • Cognitive Development One Year After Infantile Critical Pertussis Pediatr Crit Care Med. 2018 02; 19(2):89-97. . View in PubMed
  • Reply to Tremlett and Kanthimathinathan and to Koopman and Kneyber Am J Respir Crit Care Med. 2018 09 15; 198(6):823-824. . View in PubMed
  • Declining Procedures by Pediatric Critical Care Medicine Fellowship Trainees Front Pediatr. 2018; 6:365. . View in PubMed
  • Predicting Body Height in a Pediatric Intensive Care Unit Using Ulnar Length Front Pediatr. 2018; 6:187. . View in PubMed
  • Association Between Diastolic Blood Pressure During Pediatric In-Hospital Cardiopulmonary Resuscitation and Survival Circulation. 2018 04 24; 137(17):1784-1795. . View in PubMed
  • Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality Am J Respir Crit Care Med. 2018 07 01; 198(1):77-89. . View in PubMed
  • A clinical prediction model to identify patients at high risk of hemodynamic instability in the pediatric intensive care unit Crit Care. 2017 Nov 20; 21(1):282. . View in PubMed
  • Potential Acceptability of a Pediatric Ventilator Management Computer Protocol Pediatr Crit Care Med. 2017 Nov; 18(11):1027-1034. . View in PubMed
  • Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol? Pediatr Crit Care Med. 2017 Nov; 18(11):e521-e529.. View in PubMed
  • Risk Factors for Pediatric Extubation Failure: The Importance of Respiratory Muscle Strength Crit Care Med. 2017 Aug; 45(8):e798-e805. . View in PubMed
  • Functional Status of Neonatal and Pediatric Patients After Extracorporeal Membrane Oxygenation Pediatr Crit Care Med. 2017 Jun; 18(6):561-570. . View in PubMed
  • Volume and Pressure Delivery During Pediatric High-Frequency Oscillatory Ventilation Pediatr Crit Care Med. 2017 Apr; 18(4):e189-e194. . View in PubMed
  • Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial JPEN J Parenter Enteral Nutr. 2017 11; 41(8):1325-1335. . View in PubMed
  • The Relationship between High Flow Nasal Cannula Flow Rate and Effort of Breathing in ChildrenJ Pediatr. 2017 10; 189:66-71. e3. . View in PubMed
  • Mechanical Ventilation and Decision Support in Pediatric Intensive Care Pediatr Clin North Am. 2017 10; 64(5):1057-1070. . View in PubMed
  • Pseudomonas aeruginosa and post-tracheotomy bacterial respiratory tract infection readmissions Pediatr Pulmonol. 2017 09; 52(9):1212-1218. . View in PubMed
  • Cardiac output and systemic vascular resistance: Clinical assessment compared with a noninvasive objective measurement in children with shock J Crit Care. 2017 06; 39:6-10. . View in PubMed
  • Comparison of Effort of Breathing for Infants on Nasal Modes of Respiratory SupportJ Pediatr. 2017 06; 185:26-32. e3. . View in PubMed
  • Change in Oxygen Consumption Following Inhalation of Albuterol in Comparison with Levalbuterol in Healthy Adult Volunteers Lung. 2017 04; 195(2):233-239. . View in PubMed
  • CPAP alone best estimates post-extubation effort during spontaneous breathing trials in children Intensive Care Med. 2017 01; 43(1):150-151. . View in PubMed
  • Evaluating the Performance of the Pediatric Acute Lung Injury Consensus Conference Definition of Acute Respiratory Distress Syndrome Pediatr Crit Care Med. 2017 01; 18(1):17-25. . View in PubMed
  • Factors Associated with Bleeding and Thrombosis in Children Receiving Extracorporeal Membrane Oxygenation Am J Respir Crit Care Med. 2017 09 15; 196(6):762-771. . View in PubMed
  • Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children N Engl J Med. 2017 01 26; 376(4):318-329. . View in PubMed
  • Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post Hoc Analysis of the CRISIS Trial Pediatr Infect Dis J. 2016 Nov; 35(11):1182-1186. . View in PubMed
  • Computerized Decision Support Systems for Mechanical Ventilation in Children J Pediatr Intensive Care. 2016 Sep; 5(3):95-100. . View in PubMed
  • Letter to Editor: Reliability of the Ultrasound Cardiac Output Monitor for Pediatric Patients Pediatr Cardiol. 2016 Aug; 37(6):1189-90. . View in PubMed
  • Pediatric extubation readiness tests should not use pressure support Intensive Care Med. 2016 Aug; 42(8):1214-22. . View in PubMed
  • Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs Crit Care Med. 2016 Apr; 44(4):798-808. . View in PubMed
  • Delivery of Epinephrine in the Vapor Phase for the Treatment of Croup Pediatr Crit Care Med. 2016 Apr; 17(4):e177-81. . View in PubMed
  • Reply to Letter to the Editor Pediatr Cardiol. 2016 Mar; 37(3):619-20. . View in PubMed
  • Case Study: Semantic Annotation of a Pediatric Critical Care Research Study Comput Inform Nurs. 2016 Mar; 34(3):101-4. . View in PubMed
  • Obesity and Mortality Risk in Critically Ill Children Pediatrics. 2016 Mar; 137(3):e20152035. . View in PubMed
  • Limiting and Withdrawing Life Support in the PICU: For Whom Are These Options Discussed? Pediatr Crit Care Med. 2016 Feb; 17(2):110-20.. View in PubMed
  • An Official American Thoracic Society/European Respiratory Society Workshop Report: Evaluation of Respiratory Mechanics and Function in the Pediatric and Neonatal Intensive Care Units Ann Am Thorac Soc. 2016 Feb; 13(2):S1-11. . View in PubMed
  • Evaluating Risk Factors for Pediatric Post-extubation Upper Airway Obstruction Using a Physiology-based Tool Am J Respir Crit Care Med. 2016 Jan 15; 193(2):198-209. . View in PubMed
  • The Pediatric Risk of Mortality Score: Update 2015 Pediatr Crit Care Med. 2016 Jan; 17(1):2-9. . View in PubMed
  • Research as a Standard of Care in the PICU Pediatr Crit Care Med. 2016 Jan; 17(1):e13-21. . View in PubMed
  • The authors reply Crit Care Med. 2016 Jan; 44(1):e52-3. . View in PubMed
  • Validation of an Ultrasound Cardiac Output Monitor as a Bedside Tool for Pediatric Patients Pediatr Cardiol. 2016 Jan; 37(1):177-83. . View in PubMed
  • Monitoring Dead Space in Mechanically Ventilated Children: Volumetric Capnography Versus Time-Based Capnography Respir Care. 2015 Nov; 60(11):1548-55. . View in PubMed
  • Comparison of Tidal Volumes at the Endotracheal Tube and at the Ventilator Pediatr Crit Care Med. 2015 Nov; 16(9):e324-31. . View in PubMed
  • Higher Dead Space Is Associated With Increased Mortality in Critically Ill Children Crit Care Med. 2015 Nov; 43(11):2439-45. . View in PubMed
  • End-of-Life Practices Among Tertiary Care PICUs in the United States: A Multicenter Study Pediatr Crit Care Med. 2015 Sep; 16(7):e231-8. . View in PubMed
  • Simultaneous Prediction of New Morbidity, Mortality, and Survival Without New Morbidity From Pediatric Intensive Care: A New Paradigm for Outcomes Assessment Crit Care Med. 2015 Aug; 43(8):1699-709. . View in PubMed
  • Monitoring of children with pediatric acute respiratory distress syndrome: proceedings from the Pediatric Acute Lung Injury Consensus Conference Pediatr Crit Care Med. 2015 Jun; 16(5 Suppl 1):S86-101. . View in PubMed
  • Meaning making during parent-physician bereavement meetings after a child’s death Health Psychol. 2015 Apr; 34(4):453-61. . View in PubMed
  • Association of bleeding and thrombosis with outcome in extracorporeal life support Pediatr Crit Care Med. 2015 Feb; 16(2):167-74. . View in PubMed
  • Respiratory inductance plethysmography calibration for pediatric upper airway obstruction: an animal model Pediatr Res. 2015 Jan; 77(1-1):75-83. . View in PubMed
  • Pulse oximetry vsPaO2 metrics in mechanically ventilated children: Berlin definition of ARDS and mortality risk. Intensive Care Med. 2015 Jan; 41(1):94-102. . View in PubMed
  • Pediatric intensive care outcomes: development of new morbidities during pediatric critical care Pediatr Crit Care Med. 2014 Nov; 15(9):821-7. . View in PubMed
  • Increase in oxygen consumption after albuterol inhalation in ventilated infants and children Pediatr Crit Care Med. 2014 Nov; 15(9):e389-92. . View in PubMed
  • A single nucleotide polymorphism in the corticotropin receptor gene is associated with a blunted cortisol response during pediatric critical illness Pediatr Crit Care Med. 2014 Oct; 15(8):698-705. . View in PubMed
  • Algorithms to estimate PaCO2 and pH using noninvasive parameters for children with hypoxemic respiratory failure Respir Care. 2014 Aug; 59(8):1248-57. . View in PubMed
  • Relationship between the functional status scale and the pediatric overall performance category and pediatric cerebral performance category scales JAMA Pediatr. 2014 Jul; 168(7):671-6. . View in PubMed
  • Effort of breathing in children receiving high-flow nasal cannula Pediatr Crit Care Med. 2014 Jan; 15(1):1-6. . View in PubMed
  • Impact of positive end-expiratory pressure on cardiac index measured by ultrasound cardiac output monitor* Pediatr Crit Care Med. 2014 Jan; 15(1):15-20. . View in PubMed
  • Elevated positive end-expiratory pressure decreases cardiac index in a rhesus monkey model Front Pediatr. 2014; 2:134. . View in PubMed
  • Accuracy of pulse oximetry in children Pediatrics. 2014 Jan; 133(1):22-9. . View in PubMed
  • Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child’s death in the PICU Crit Care Med. 2014 Jan; 42(1):148-57. . View in PubMed
  • Genome Sequences of 28 Bordetella pertussis US. Outbreak Strains Dating from 2010 to 2012. Genome Announc. 2013 Dec 19; 1(6). . View in PubMed
  • Ratio of PICU versus ward cardiopulmonary resuscitation events is increasing Crit Care Med. 2013 Oct; 41(10):2292-7. . View in PubMed
  • Impact of gender on sepsis mortality and severity of illness for prepubertal and postpubertal childrenJ Pediatr. 2013 Sep; 163(3):835-40. e1. . View in PubMed
  • Pediatric upper airway obstruction: interobserver variability is the road to perdition J Crit Care. 2013 Aug; 28(4):490-7. . View in PubMed
  • The ideal time interval for critical care severity-of-illness assessment Pediatr Crit Care Med. 2013 Jun; 14(5):448-53. . View in PubMed
  • The role of the Data and Safety Monitoring Board in a clinical trial: the CRISIS study Pediatr Crit Care Med. 2013 May; 14(4):374-83. . View in PubMed
  • Critical pertussis illness in children: a multicenter prospective cohort study Pediatr Crit Care Med. 2013 May; 14(4):356-65. . View in PubMed
  • Baseline serum concentrations of zinc, selenium, and prolactin in critically ill children Pediatr Crit Care Med. 2013 May; 14(4):e202-6. . View in PubMed
  • Physicians’ conceptualization of “closure” as a benefit of physician-parent follow-up meetings after a child’s death in the pediatric intensive care unit J Palliat Care. 2013; 29(2):69-75. . View in PubMed
  • Opioid analgesia in mechanically ventilated children: results from the multicenter Measuring Opioid Tolerance Induced by Fentanyl study Pediatr Crit Care Med. 2013 Jan; 14(1):27-36. . View in PubMed
  • Fatal and near-fatal asthma in children: the critical care perspectiveJ Pediatr. 2012 Aug; 161(2):214-21. e3. . View in PubMed
  • Critical care for pediatric asthma: wide care variability and challenges for study Pediatr Crit Care Med. 2012 Jul; 13(4):407-14. . View in PubMed
  • Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury Crit Care Med. 2012 Apr; 40(4):1309-16. . View in PubMed
  • The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial Pediatr Crit Care Med. 2012 Mar; 13(2):165-73. . View in PubMed
  • The association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure Pediatr Crit Care Med. 2012 Jan; 13(1):11-5. . View in PubMed
  • Variability in usual care mechanical ventilation for pediatric acute lung injury: the potential benefit of a lung protective computer protocol Intensive Care Med. 2011 Nov; 37(11):1840-8. . View in PubMed
  • Real-time free cortisol quantification among critically ill children Pediatr Crit Care Med. 2011 Sep; 12(5):525-31. . View in PubMed
  • The Collaborative Pediatric Critical Care Research Network Critical Pertussis Study: collaborative research in pediatric critical care medicine Pediatr Crit Care Med. 2011 Jul; 12(4):387-92. . View in PubMed
  • A framework for conducting follow-up meetings with parents after a child’s death in the pediatric intensive care unit Pediatr Crit Care Med. 2011 Mar; 12(2):147-52. . View in PubMed
  • Physicians’ experiences and perspectives regarding follow-up meetings with parents after a child’s death in the pediatric intensive care unit Pediatr Crit Care Med. 2011 Mar; 12(2):e64-8. . View in PubMed
  • Follow-up study of complicated grief among parents eighteen months after a child’s death in the pediatric intensive care unit J Palliat Med. 2011 Feb; 14(2):207-14. . View in PubMed
  • If the tube fits? Pediatr Crit Care Med. 2011 Jan; 12(1):117-8.. View in PubMed
  • The design of future pediatric mechanical ventilation trials for acute lung injury Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1465-74. . View in PubMed
  • Complicated grief and associated risk factors among parents following a child’s death in the pediatric intensive care unit Arch Pediatr Adolesc Med. 2010 Nov; 164(11):1045-51. . View in PubMed
  • Acute lung injury in children: therapeutic practice and feasibility of international clinical trials Pediatr Crit Care Med. 2010 Nov; 11(6):681-9. . View in PubMed
  • Glucose variability and survival in critically ill children: allostasis or harm? Pediatr Crit Care Med. 2010 Nov; 11(6):707-12.. View in PubMed
  • Pressure-rate product and phase angle as measures of acute inspiratory upper airway obstruction in rhesus monkeys Pediatr Pulmonol. 2010 Jul; 45(7):639-44. . View in PubMed
  • Tolerance and withdrawal from prolonged opioid use in critically ill children Pediatrics. 2010 May; 125(5):e1208-25. . View in PubMed
  • Collaborative pediatric critical care research network: looking back and moving forward Pediatr Crit Care Med. 2010 Jan; 11(1):1-6. . View in PubMed
  • Effect of tidal volume in children with acute hypoxemic respiratory failure Intensive Care Med. 2009 Aug; 35(8):1428-37. . View in PubMed
  • Rationale and design of the pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial JPEN J Parenter Enteral Nutr. 2009 Jul-Aug; 33(4):368-74. . View in PubMed
  • Is “rescue” therapy ethical in randomized controlled trials? Pediatr Crit Care Med. 2009 Jul; 10(4):431-8.. View in PubMed
  • Assessment of thoraco-abdominal asynchrony Paediatr Respir Rev. 2009 Jun; 10(2):75-80. . View in PubMed
  • Comparison of the pulse oximetric saturation/fraction of inspired oxygen ratio and the PaO2/fraction of inspired oxygen ratio in children Chest. 2009 Mar; 135(3):662-668. . View in PubMed
  • Disseminated intravascular coagulation score is associated with mortality for children with shock Intensive Care Med. 2009 Feb; 35(2):327-33. . View in PubMed
  • Accounting for medical communication: parents’ perceptions of communicative roles and responsibilities in the pediatric intensive care unit Commun Med. 2009; 6(2):177-88. . View in PubMed
  • Weaning and extubation readiness in pediatric patients Pediatr Crit Care Med. 2009 Jan; 10(1):1-11. . View in PubMed
  • The mechanics of breathing in children with acute severe croup Intensive Care Med. 2008 Feb; 34(2):324-32. . View in PubMed
  • The effect of epinephrine by nebulization on measures of airway obstruction in patients with acute severe croup Intensive Care Med. 2008 Jan; 34(1):138-47. . View in PubMed
  • Parents’ perspectives on physician-parent communication near the time of a child’s death in the pediatric intensive care unit Pediatr Crit Care Med. 2008 Jan; 9(1):2-7. . View in PubMed
  • Infant botulism: a 30-year experience spanning the introduction of botulism immune globulin intravenous in the intensive care unit at Childrens Hospital Los Angeles Pediatrics. 2007 Dec; 120(6):e1380-5. . View in PubMed
  • Parents’ perspectives regarding a physician-parent conference after their child’s death in the pediatric intensive care unitJ Pediatr. 2007 Jul; 151(1):50-555. e1-2. . View in PubMed
  • Positive end-expiratory pressure and pressure support in peripheral airways obstruction : work of breathing in intubated children Intensive Care Med. 2007 Jan; 33(1):120-7. . View in PubMed
  • Collaborative Pediatric Critical Care Research Network (CPCCRN) Pediatr Crit Care Med. 2006 Jul; 7(4):301-7. . View in PubMed
  • Pressure-rate products and phase angles in children on minimal support ventilation and after extubation Intensive Care Med. 2005 Dec; 31(12):1700-5. . View in PubMed
  • The use of cuffed versus uncuffed endotracheal tubes in pediatric intensive care J Pediatr. 2004 Mar; 144(3):333-7. . View in PubMed
  • Measurement of lung volume in mechanically ventilated monkeys with an ultrasonic flow meter and the nitrogen washout method Intensive Care Med. 2004 Jan; 30(1):127-32. . View in PubMed
  • Ventilation techniques including liquid ventilation Pediatr Pulmonol Suppl. 2004; 26:125-6. . View in PubMed
  • Extubation failure in pediatric intensive care: a multiple-center study of risk factors and outcomes Crit Care Med. 2003 Nov; 31(11):2657-64. . View in PubMed
  • Effect of forced deflation maneuvers upon measurements of respiratory mechanics in ventilated infants Intensive Care Med. 2003 Nov; 29(11):2004-8. . View in PubMed
  • Dynamic respiratory system mechanics in infants during pressure and volume controlled ventilation Eur Respir J. 2001 Jan; 17(1):115-21. . View in PubMed
  • High-frequency oscillatory ventilation in pediatric respiratory failure: a multicenter experience Crit Care Med. 2000 Dec; 28(12):3913-9. . View in PubMed
  • Analysis of nonlinear volume-dependent respiratory system mechanics in pediatric patients Pediatr Crit Care Med. 2000 Oct; 1(2):111-8. . View in PubMed
  • Blunt traumatic injury to the coronary arteries and pulmonary artery in a child J Trauma. 2000 Sep; 49(3):550-2. . View in PubMed
  • Time course of severe respiratory syncytial virus infection in mechanically ventilated infants Acta Paediatr. 2000 Aug; 89(8):893-5. . View in PubMed
  • The pharmacologic mechanism by which inhaled epinephrine reduces airway obstruction in respiratory syncytial virus-associated bronchiolitis J Pediatr. 2000 May; 136(5):699-700. . View in PubMed
  • Impact of respiratory syncytial virus infection on surgery for congenital heart disease: postoperative course and outcome Crit Care Med. 1999 Sep; 27(9):1974-81. . View in PubMed
  • Effect of inhaled nitric oxide on respiratory mechanics in ventilated infants with RSV bronchiolitis Intensive Care Med. 1999 Jan; 25(1):81-7. . View in PubMed
  • Pulmonary function in ventilated infants with bronchiolitis Pediatr Pulmonol. 1998 Dec; 26(6):438-41. . View in PubMed
  • Total lung capacity by N2 washout from high and low lung volumes in ventilated infants and children Am J Respir Crit Care Med. 1998 Aug; 158(2):526-31. . View in PubMed
  • Effect of prone and supine positions on functional residual capacity, oxygenation, and respiratory mechanics in ventilated infants and children Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 1):1185-9. . View in PubMed
  • Continuous versus intermittent furosemide infusion in critically ill infants after open heart operations Ann Thorac Surg. 1997 Oct; 64(4):1133-9. . View in PubMed
  • Multiple-breath nitrogen washout techniques: including measurements with patients on ventilators Eur Respir J. 1997 Sep; 10(9):2174-85. . View in PubMed
  • The effects of bronchodilators on spontaneous ventilation and oxygen consumption in rhesus monkeys Pediatr Res. 1997 Aug; 42(2):157-62. . View in PubMed
  • Influence of endotracheal tube diameter on forced deflation flow-volume curves in rhesus monkeys Eur Respir J. 1997 Aug; 10(8):1870-3. . View in PubMed
  • Assessment of pulmonary function in the early phase of ARDS in pediatric patients Pediatr Pulmonol. 1997 Mar; 23(3):169-75. . View in PubMed
  • Acute respiratory distress syndrome caused by respiratory syncytial virus Pediatr Pulmonol. 1997 Mar; 23(3):176-83. . View in PubMed
  • Flow limitation in anesthetized rhesus monkeys: a comparison of rapid thoracoabdominal compression and forced deflation techniques Pediatr Res. 1996 Mar; 39(3):539-46. . View in PubMed
  • Infant lung function testing in the intensive care unit Intensive Care Med. 1995 Sep; 21(9):744-52. . View in PubMed
  • Rapid chest compression and flow limitation Eur Respir J. 1995 Sep; 8(9):1627-8. . View in PubMed
  • Albuterol responsiveness in infants with respiratory failure caused by respiratory syncytial virus infection J Pediatr. 1995 Sep; 127(3):485-90. . View in PubMed
  • Severity of hypoxia predicts response to nitric oxide in a porcine pulmonary hypertension model J Pediatr Surg. 1995 Jul; 30(7):930-5; discussion 935-6. . View in PubMed
  • Effects of maternal and sibling deprivation on basal and stress induced hypothalamic-pituitary-adrenal components in the infant rat Neurosci Lett. 1995 Jun 02; 192(1):49-52. . View in PubMed
  • Validation of the phase angle technique as an objective measure of upper airway obstruction Pediatr Pulmonol. 1995 Mar; 19(3):167-73. . View in PubMed
  • Assessment of lung function in the intensive care unit Pediatr Pulmonol. 1995 Feb; 19(2):118-28. . View in PubMed
  • Cuffed endotracheal tubes in pediatric intensive care J Pediatr. 1994 Jul; 125(1):57-62. . View in PubMed
  • The pharmacokinetics of isoproterenol in critically ill pediatric patients J Clin Pharmacol. 1993 Jan; 33(1):29-34. . View in PubMed
  • Laryngotracheobronchitis as a complication of measles during an urban epidemic J Pediatr. 1992 Oct; 121(4):511-5. . View in PubMed
  • Intensive care course and outcome of patients infected with respiratory syncytial virus Pediatr Pulmonol. 1992 Jul; 13(3):143-50. . View in PubMed
  • Estimation of arterial carbon dioxide by end-tidal and transcutaneous PCO2 measurements in ventilated children Pediatr Pulmonol. 1992 Mar; 12(3):153-7. . View in PubMed
  • The effects of varying inflation and deflation pressures on the maximal expiratory deflation flow-volume relationship in anesthetized rhesus monkeys Am Rev Respir Dis. 1991 Oct; 144(4):807-13. . View in PubMed
  • Pharmacokinetics of dopamine in infants and children Crit Care Med. 1991 Aug; 19(8):1008-11. . View in PubMed
  • The pharmacokinetics of dobutamine in pediatric intensive care unit patients Drug Metab Dispos. 1991 May-Jun; 19(3):614-9. . View in PubMed
  • The ventilatory and oxygen costs in the anesthetized rhesus monkey of inhaling drugs used in the therapy and diagnosis of asthma Am Rev Respir Dis. 1991 Apr; 143(4 Pt 1):766-71. . View in PubMed
  • Effect of positive end-expiratory pressure on respiratory compliance in children with acute respiratory failure Pediatr Pulmonol. 1991; 11(2):103-7. . View in PubMed
  • Outcome of oncology patients in the pediatric intensive care unit Intensive Care Med. 1991; 17(1):11-5. . View in PubMed
  • Rib cage to abdominal asynchrony in children undergoing polygraphic sleep studies Pediatr Pulmonol. 1991; 11(2):141-6. . View in PubMed
  • Functional residual capacity in ventilated infants and children Pediatr Res. 1990 Nov; 28(5):451-4. . View in PubMed
  • An automated bedside method for measuring functional residual capacity by N2 washout in mechanically ventilated children Pediatr Res. 1990 Nov; 28(5):446-50. . View in PubMed
  • Thoracoabdominal asynchrony in acute upper airway obstruction in small children Am Rev Respir Dis. 1990 Sep; 142(3):540-4. . View in PubMed
  • Viewpoint: untoward effects of beta-adrenoceptor agonists in asthma Eur Respir J. 1990 Feb; 3(2):228-33. . View in PubMed
  • Factors affecting accidental extubations in neonatal and pediatric intensive care patients Crit Care Med. 1990 Feb; 18(2):163-5. . View in PubMed
  • Adult respiratory distress syndrome in severely neutropenic children Pediatr Pulmonol. 1990; 8(2):104-8. . View in PubMed
  • Varying tracheal cross-sectional area during respiration in infants and children with suspected upper airway obstruction by computed cinetomography scanning Pediatr Pulmonol. 1990; 9(4):224-32. . View in PubMed
  • Vecuronium by continuous infusion for neuromuscular blockade in infants and children Crit Care Med. 1989 Oct; 17(10):989-92. . View in PubMed
  • In vitro performance of the small particle aerosol generator (SPAG-2) Pediatr Pulmonol. 1989; 7(3):183-8. . View in PubMed
  • Respiratory disease and respiratory failure: implications for the young and the old Br J Dis Chest. 1986 Jul; 80(3):209-17. . View in PubMed
  • Effort and volume dependence of forced-deflation flow-volume relationships in intubated infants J Appl Physiol (1985). 1996 Jan; 80(1):345-50. . View in PubMed
  • Measurement of high lung volumes by nitrogen washout method J Appl Physiol (1985). 1994 Sep; 77(3):1562-4. . View in PubMed
  • Anatomic dead space in infants and children J Appl Physiol (1985). 1996 May; 80(5):1485-9. . View in PubMed
  • Effect of lung volume on forced expiratory flows during rapid thoracoabdominal compression in infants J Appl Physiol (1985). 1995 May; 78(5):1993-7. . View in PubMed
  • Use of sustained release Somophyllin-12 capsules in young asthmatic children Br J Clin Pract Suppl. 1984; 35:64-7. . View in PubMed
  • Combined beta agonists and methylxanthines in asthma N Engl J Med. 1983 Aug 18; 309(7):432-3. . View in PubMed
  • Respiratory status of children with epiglottitis with and without an artificial airway Am J Dis Child. 1983 Feb; 137(2):139-41. . View in PubMed
  • Comparison of nebulised sodium cromoglycate and oral theophylline in controlling symptoms of chronic asthma in pre-school children: a double blind study Aust N Z J Med. 1982 Jun; 12(3):232-8. . View in PubMed
  • Sustained-release theophylline: a significant advance in the treatment of childhood asthma J Pediatr. 1982 Mar; 100(3):489-92. . View in PubMed
  • Sustained-release theophylline for childhood asthma: evidence for circadian variation of theophylline pharmacokinetics J Pediatr. 1981 Sep; 99(3):476-9. . View in PubMed
  • Malabsorption of medium-chain triglycerides in infants with cystic fibrosis: correction with pancreatic enzyme supplement J Pediatr. 1980 May; 96(5):862-4. . View in PubMed
  • Recognition and management of respiratory failure Pediatr Clin North Am. 1979 Aug; 26(3):617-43. . View in PubMed
  • The respiratory status of children with croup J Pediatr. 1972 Dec; 81(6):1068-73. . View in PubMed