Daniel George Arkfeld, MD

Professor of Clinical Medicine

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A Los Angeles native, Dr. Arkfeld, first joined the Keck School of Medicine faculty in 1994 after completing a fellowship at Cedars-Sinai Medical Center in West LA. Prior to his current administrative position as Director of Rheumatology CME Educational courses, Dr. Arkfeld was Chief of Rheumatology Clinic at LAC+USC Medical Center.

As a cliniccal professor, Dr. Arkfeld’s major areas of research interests include rheumatoid arthritis, fibromyalgia, and Sjogren’s Syndrome. In addition to being a renowned lecturer, having spoken all across the globe, Dr. Arkfeld is also a former little league baseball coach and doctor for the USC Women’s Basketball Team.


  • American College of Rheumatology: Mentor Award, 2013
  • American College of Rheumatology: Mentor Award, 2009
  • American College of Rheumatology: Mentor Award, 2007
  • University of Southern California: Second Year Medical Student Teaching Award, 1999


  • Rituximab Induced Flare of Psoriatic Arthritis in a Patient with Devic’s Syndrome: A Case Report Curr Rheumatol Rev. 2024 Feb 29. . View in PubMed
  • Potential Benefits of Psilocybin for Lupus Pain: A Case Report Curr Rheumatol Rev. 2024; 20(1):97-99. . View in PubMed
  • Clinical Image: Eczema herpeticum in a patient with rheumatoid arthritis and dry eye syndrome ACR Open Rheumatol. 2023 Dec 26. . View in PubMed
  • Arteritic Anterior Ischemic Optic Neuropathy and Central Retinal Artery Occlusion in Polyarteritis Nodosa J Neuroophthalmol. 2023 Jun 19. . View in PubMed
  • The time to offer treatments for COVID-19 Expert Opin Investig Drugs. 2021 May; 30(5):505-518. . View in PubMed
  • The Importance of Understanding the Stages of COVID-19 in Treatment and Trials AIDS Rev. 2021 02 08; 23(1):40-47. . View in PubMed
  • A patient with primary Sjogren’s syndrome, cystic lung disease, and MALT lymphoma treated successfully with rituximab: a case-based review Clin Rheumatol. 2020 Apr; 39(4):1357-1362. . View in PubMed
  • Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients Sci Rep. 2018 07 23; 8(1):11044. . View in PubMed
  • Low Dose Naltrexone in the Treatment of Fibromyalgia Curr Rheumatol Rev. 2018; 14(2):177-180. . View in PubMed
  • Autoinflammation and Immunomodulation in Inflammatory Fibromyalgia Syndrome- A Review Curr Rheumatol Rev. 2017; 13(2):98-102. . View in PubMed
  • Rheumatologic manifestations of the “MonoMAC” syndromea systematic review. Clin Rheumatol. 2015 Sep; 34(9):1643-5. . View in PubMed
  • Priapism after tumor necrosis factor alpha inhibitor use Clin Rheumatol. 2015 Apr; 34(4):801-2. . View in PubMed
  • Diagnosis of latent tuberculosis infection with T-SPOT(®)TB in a predominantly immigrant population with rheumatologic disorders. Lung. 2015 Feb; 193(1):3-11. . View in PubMed
  • Inflammatory Fibromyalgia: Is it Real? Curr Rheumatol Rev. 2015; 11(1):15-17.. View in PubMed
  • Tear cathepsin S as a candidate biomarker for Sjögren’s syndrome Arthritis Rheumatol. 2014 Jul; 66(7):1872-81. . View in PubMed
  • Neurosarcoidosis mimicking multiple sclerosis successfully treated with methotrexate and adalimumab Int J Rheum Dis. 2014 Feb; 17(2):214-6. . View in PubMed
  • Giant cell arteritis with visual loss following zoledronic acid infusion Int J Rheum Dis. 2014 Jan; 17(1):113-5. . View in PubMed
  • Reversal of chronic refractory tophaceous gout with erosions with pegloticase Int J Rheum Dis. 2013 Jun; 16(3):369-70. . View in PubMed
  • Treatment of multicentric reticulohistiocytosis with adalimumab, minocycline, methotrexate Int J Rheum Dis. 2013 Feb; 16(1):105-6. . View in PubMed
  • Pregnancy in a patient with gouty arthritis secondary to pseudo-Bartter syndrome J Clin Rheumatol. 2010 Aug; 16(5):219-20. . View in PubMed
  • Development of anti-CCP-positive rheumatoid arthritis following pegylated interferon-a2a treatment for chronic hepatitis C infection J Rheumatol. 2010 Aug 01; 37(8):1777. . View in PubMed
  • Immune thrombocytopenia in patients with connective tissue disorders and the antiphospholipid antibody syndrome Hematol Oncol Clin North Am. 2009 Dec; 23(6):1239-49. . View in PubMed
  • Adalimumab-induced noncaseating granuloma in the bone marrow of a patient being treated for rheumatoid arthritis Rheumatol Int. 2009 Feb; 29(4):437-9. . View in PubMed
  • Facebook medicine J Rheumatol. 2009 Jan; 36(1):211. . View in PubMed
  • Higher gonorrhea rates among African Americans than among White persons in the United States Ann Intern Med. 2008 Mar 18; 148(6):482; author reply 482. . View in PubMed
  • Biological significance of anti-cyclic citrullinated peptide antibody in rheumatoid arthritis Ann Intern Med. 2008 Mar 04; 148(5):403; author reply 403-4. . View in PubMed
  • How is infliximab harmful? Ann Intern Med. 2008 Jan 15; 148(2):166; author reply 166.. View in PubMed
  • The potential utility of B cell-directed biologic therapy in autoimmune diseases Rheumatol Int. 2008 Jan; 28(3):205-15. . View in PubMed
  • The use of the tumour necrosis factor antagonist infliximab in heart transplant recipients: two case reports Ann Rheum Dis. 2007 Nov; 66(11):1544-5. . View in PubMed
  • Successful rituximab therapy of acquired factor VIII inhibitor in a patient with rheumatoid arthritis J Clin Rheumatol. 2007 Apr; 13(2):89-91. . View in PubMed
  • Rituximab treatment for resistant antiphospholipid syndrome J Rheumatol. 2006 Feb; 33(2):355-7. . View in PubMed
  • Myositis ossificans: a case report Arthritis Rheum. 2005 Oct 15; 53(5):793-5. . View in PubMed
  • Hip arthroplasty in a 101-year-old patient J Clin Rheumatol. 2005 Jun; 11(3):180. . View in PubMed
  • Quest for the Holy Grail to cure arthritis and osteoporosis: emphasis on bone drug delivery systems Adv Drug Deliv Rev. 2005 May 25; 57(7):939-44. . View in PubMed
  • Development of Crohn’s disease in a patient taking etanercept J Rheumatol. 2005 Apr; 32(4):752-3. . View in PubMed
  • Adult Still’s disease in a 75-year-old patient J Am Geriatr Soc. 2004 Dec; 52(12):2144-5. . View in PubMed
  • Infliximab treatment of Familial Mediterranean fever and its effect on secondary AA amyloidosis J Clin Rheumatol. 2004 Jun; 10(3):134-7. . View in PubMed
  • Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis Arthritis Rheum. 2003 Apr; 48(4):982-92. . View in PubMed
  • Etanercept therapy in rheumatoid arthritisA randomized, controlled trial. Ann Intern Med. 1999 Mar 16; 130(6):478-86. . View in PubMed
  • Treatment of rheumatoid arthritis N Engl J Med. 1996 Sep 12; 335(11):821-2; author reply 822-3. . View in PubMed
  • Identification of Neisseria gonorrhoeae in synovial fluid using the polymerase chain reaction Arthritis Rheum. 1994 May; 37(5):702-9. . View in PubMed