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Daniel George Arkfeld, MD

Professor of Clinical Medicine

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Phone +1 323 442 1946
Email arkfeld@usc.edu
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Overview

A Los Angeles native, Dr. Arkfeld, first joined the Keck School of Medicine faculty in 1994 after completing a fellowship at Cedars-Sinai Medical Center in West LA. Prior to his current administrative position as Director of Rheumatology CME Educational courses, Dr. Arkfeld was Chief of Rheumatology Clinic at LAC+USC Medical Center. As a cliniccal professor, Dr. Arkfeld’s major areas of research interests include rheumatoid arthritis, fibromyalgia, and Sjogren’s Syndrome. In addition to being a renowned lecturer, having spoken all across the globe, Dr. Arkfeld is also a former little league baseball coach and doctor for the USC Women’s Basketball Team.

Awards

  • American College of Rheumatology: Mentor Award, 2013
  • American College of Rheumatology: Mentor Award, 2009
  • American College of Rheumatology: Mentor Award, 2007
  • University of Southern California: Second Year Medical Student Teaching Award, 1999

Publications

  • Scurvy in a Patient with Crohn’s Disease: A Case Report. Curr Rheumatol Rev. 2025 Aug 11.. View in PubMed
  • Discoid Lupus Flare with Chondritis Triggered by Eaton Fire Case Report. Curr Rheumatol Rev. 2025 Jul 24.. View in PubMed
  • A Rare Presentation of Cryoglobulinemic Vasculitis Associated with Primary Sjögren’s Syndrome. Curr Rheumatol Rev. 2025; 21(4):480-486.. View in PubMed
  • Rituximab Induced Flare of Psoriatic Arthritis in a Patient with Devic’s Syndrome: A Case Report. Curr Rheumatol Rev. 2025; 21(1):109-112.. View in PubMed
  • Arteritic Anterior Ischemic Optic Neuropathy and Central Retinal Artery Occlusion in Polyarteritis Nodosa. J Neuroophthalmol. 2024 Sep 01; 44(3):e332-e333.. View in PubMed
  • The Effect of Low-Dose Glucocorticoids Over Two Years on Weight and Blood Pressure in Rheumatoid Arthritis. Ann Intern Med. 2024 04; 177(4):545.. View in PubMed
  • Clinical Image: Eczema herpeticum in a patient with rheumatoid arthritis and dry eye syndrome. ACR Open Rheumatol. 2024 Mar; 6(3):137.. View in PubMed
  • Potential Benefits of Psilocybin for Lupus Pain: A Case Report. Curr Rheumatol Rev. 2024; 20(1):97-99.. View in PubMed
  • Chronic Pain in Patients with Rheumatoid Arthritis. Curr Pain Headache Rep. 2021 Jul 16; 25(9):59.. View in PubMed
  • The time to offer treatments for COVID-19. Expert Opin Investig Drugs. 2021 May; 30(5):505-518.. View in PubMed
  • The Importance of Understanding the Stages of COVID-19 in Treatment and Trials. AIDS Rev. 2021 02 08; 23(1):40-47.. View in PubMed
  • Linear Morphea With Inflammatory Myositis. J Hand Surg Am. 2020 Aug; 45(8):782.e1-782.e5.. View in PubMed
  • A patient with primary Sjogren’s syndrome, cystic lung disease, and MALT lymphoma treated successfully with rituximab: a case-based review. Clin Rheumatol. 2020 Apr; 39(4):1357-1362.. View in PubMed
  • Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients. Sci Rep. 2018 07 23; 8(1):11044.. View in PubMed
  • Low Dose Naltrexone in the Treatment of Fibromyalgia. Curr Rheumatol Rev. 2018; 14(2):177-180.. View in PubMed
  • Autoinflammation and Immunomodulation in Inflammatory Fibromyalgia Syndrome- A Review. Curr Rheumatol Rev. 2017; 13(2):98-102.. View in PubMed
  • Rheumatologic manifestations of the “MonoMAC” syndrome. a systematic review. Clin Rheumatol. 2015 Sep; 34(9):1643-5.. View in PubMed
  • Priapism after tumor necrosis factor alpha inhibitor use. Clin Rheumatol. 2015 Apr; 34(4):801-2.. View in PubMed
  • Diagnosis of latent tuberculosis infection with T-SPOT(®).TB in a predominantly immigrant population with rheumatologic disorders. Lung. 2015 Feb; 193(1):3-11.. View in PubMed
  • Inflammatory Fibromyalgia: Is it Real? Curr Rheumatol Rev. 2015; 11(1):15-17.. View in PubMed
  • Tear cathepsin S as a candidate biomarker for Sjögren’s syndrome. Arthritis Rheumatol. 2014 Jul; 66(7):1872-81.. View in PubMed
  • Neurosarcoidosis mimicking multiple sclerosis successfully treated with methotrexate and adalimumab. Int J Rheum Dis. 2014 Feb; 17(2):214-6.. View in PubMed
  • Giant cell arteritis with visual loss following zoledronic acid infusion. Int J Rheum Dis. 2014 Jan; 17(1):113-5.. View in PubMed
  • Reversal of chronic refractory tophaceous gout with erosions with pegloticase. Int J Rheum Dis. 2013 Jun; 16(3):369-70.. View in PubMed
  • Treatment of multicentric reticulohistiocytosis with adalimumab, minocycline, methotrexate. Int J Rheum Dis. 2013 Feb; 16(1):105-6.. View in PubMed
  • Development of anti-CCP-positive rheumatoid arthritis following pegylated interferon-α2a treatment for chronic hepatitis C infection. J Rheumatol. 2010 Aug 01; 37(8):1777.. View in PubMed
  • Pregnancy in a patient with gouty arthritis secondary to pseudo-Bartter syndrome. J Clin Rheumatol. 2010 Aug; 16(5):219-20.. View in PubMed
  • Immune thrombocytopenia in patients with connective tissue disorders and the antiphospholipid antibody syndrome. Hematol Oncol Clin North Am. 2009 Dec; 23(6):1239-49.. View in PubMed
  • Adalimumab-induced noncaseating granuloma in the bone marrow of a patient being treated for rheumatoid arthritis. Rheumatol Int. 2009 Feb; 29(4):437-9.. View in PubMed
  • Facebook medicine. J Rheumatol. 2009 Jan; 36(1):211.. View in PubMed
  • Higher gonorrhea rates among African Americans than among White persons in the United States. Ann Intern Med. 2008 Mar 18; 148(6):482; author reply 482.. View in PubMed
  • Biological significance of anti-cyclic citrullinated peptide antibody in rheumatoid arthritis. Ann Intern Med. 2008 Mar 04; 148(5):403; author reply 403-4.. View in PubMed
  • How is infliximab harmful? Ann Intern Med. 2008 Jan 15; 148(2):166; author reply 166.. View in PubMed
  • The potential utility of B cell-directed biologic therapy in autoimmune diseases. Rheumatol Int. 2008 Jan; 28(3):205-15.. View in PubMed
  • The use of the tumour necrosis factor antagonist infliximab in heart transplant recipients: two case reports. Ann Rheum Dis. 2007 Nov; 66(11):1544-5.. View in PubMed
  • Successful rituximab therapy of acquired factor VIII inhibitor in a patient with rheumatoid arthritis. J Clin Rheumatol. 2007 Apr; 13(2):89-91.. View in PubMed
  • Rituximab treatment for resistant antiphospholipid syndrome. J Rheumatol. 2006 Feb; 33(2):355-7.. View in PubMed
  • Myositis ossificans: a case report. Arthritis Rheum. 2005 Oct 15; 53(5):793-5.. View in PubMed
  • Hip arthroplasty in a 101-year-old patient. J Clin Rheumatol. 2005 Jun; 11(3):180.. View in PubMed
  • Quest for the Holy Grail to cure arthritis and osteoporosis: emphasis on bone drug delivery systems. Adv Drug Deliv Rev. 2005 May 25; 57(7):939-44.. View in PubMed
  • Development of Crohn’s disease in a patient taking etanercept. J Rheumatol. 2005 Apr; 32(4):752-3.. View in PubMed
  • Adult Still’s disease in a 75-year-old patient. J Am Geriatr Soc. 2004 Dec; 52(12):2144-5.. View in PubMed
  • Infliximab treatment of Familial Mediterranean fever and its effect on secondary AA amyloidosis. J Clin Rheumatol. 2004 Jun; 10(3):134-7.. View in PubMed
  • Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum. 2003 Apr; 48(4):982-92.. View in PubMed
  • Differential MHC class II-mediated presentation of rheumatoid arthritis autoantigens by human dendritic cells and macrophages. J Immunol. 2002 Dec 01; 169(11):6625-33.. View in PubMed
  • Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann Intern Med. 1999 Mar 16; 130(6):478-86.. View in PubMed
  • Treatment of rheumatoid arthritis. N Engl J Med. 1996 Sep 12; 335(11):821-2; author reply 822-3.. View in PubMed
  • Identification of Neisseria gonorrhoeae in synovial fluid using the polymerase chain reaction. Arthritis Rheum. 1994 May; 37(5):702-9.. View in PubMed

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