Keck School Faculty

Daniel Oscar Stram

Daniel Oscar Stram

Professor of Population and Public Health Sciences
Medicine
SSB 202D 2001 N. Soto Street Health Sciences Campus Los Angeles

Traffic-Related Air Pollution and Lung Cancer Incidence: The California Multiethnic Cohort Study Am J Respir Crit Care Med. 2022 Jun 01. . View in PubMed

Prognostic utility of self-reported sarcopenia (SARC-F) in the Multiethnic Cohort J Cachexia Sarcopenia Muscle. 2022 04; 13(2):987-1002. . View in PubMed

Outdoor ambient air pollution and breast cancer survival among California participants of the Multiethnic Cohort Study Environ Int. 2022 03; 161:107088. . View in PubMed

Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits Am J Hum Genet. 2022 04 07; 109(4):669-679. . View in PubMed

Dosimetry and uncertainty approaches for the million person study of low-dose radiation health effects: overview of the recommendations in NCRP Report No178. Int J Radiat Biol. 2022; 98(4):600-609. . View in PubMed

Hum Genet. 2021 Oct; 140(10):1449-1457. . View in PubMed

Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation EClinicalMedicine. 2021 Oct; 40:101093. . View in PubMed

Genetic discovery and risk characterization in type 2 diabetes across diverse populations HGG Adv. 2021 Apr 08; 2(2). . View in PubMed

The association between ambient air pollutants and pancreatic cancer in the Multiethnic Cohort Study Environ Res. 2021 11; 202:111608. . View in PubMed

Racial/ethnic disparities in weight or BMI change in adulthood and pancreatic cancer incidence: The multiethnic cohort Cancer Med. 2021 06; 10(12):4097-4106. . View in PubMed

Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium Cancer Epidemiol Biomarkers Prev. 2021 04; 30(4):623-642. . View in PubMed

Letter to the Editor Concerning Stram et al: "Lung Cancer in the Mayak Workers Cohort: Risk Estimation and Uncertainty Analysis. " Radiat Res 2021; 195:334-46. Radiat Res. 2021 10 01; 196(4):449-451. . View in PubMed

Associations of the gut microbiome with hepatic adiposity in the Multiethnic Cohort Adiposity Phenotype Study Gut Microbes. 2021 Jan-Dec; 13(1):1965463. . View in PubMed

Urinary phthalate exposures and risk of breast cancer: the Multiethnic Cohort study Breast Cancer Res. 2021 04 06; 23(1):44. . View in PubMed

Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility Front Genet. 2021; 12:554948. . View in PubMed

Genome-wide association study of pancreatic fat: The Multiethnic Cohort Adiposity Phenotype Study PLoS One. 2021; 16(7):e0249615. . View in PubMed

Ethnic differences in excretion of butadiene-DNA adducts by current smokers Carcinogenesis. 2021 05 28; 42(5):694-704. . View in PubMed

Ethnic Differences of Urinary Cadmium in Cigarette Smokers from the Multiethnic Cohort Study Int J Environ Res Public Health. 2021 03 06; 18(5). . View in PubMed

Risk of breast cancer and prediagnostic urinary excretion of bisphenol A, triclosan and parabens: The Multiethnic Cohort Study Int J Cancer. 2021 10 01; 149(7):1426-1434. . View in PubMed

Lung Cancer in the Mayak Workers Cohort: Risk Estimation and Uncertainty Analysis Radiat Res. 2021 04 01; 195(4):334-346. . View in PubMed

Association between Airport-Related Ultrafine Particles and Risk of Malignant Brain Cancer: A Multiethnic Cohort Study Cancer Res. 2021 08 15; 81(16):4360-4369. . View in PubMed

Multiethnic Prediction of Nicotine Biomarkers and Association With Nicotine Dependence Nicotine Tob Res. 2021 11 05; 23(12):2162-2169. . View in PubMed

A case-control study of the joint effect of reproductive factors and radiation treatment for first breast cancer and risk of contralateral breast cancer in the WECARE study Breast. 2020 Dec; 54:62-69. . View in PubMed

Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study Hepatol Commun. 2020 Aug; 4(8):1112-1123. . View in PubMed

Exposure Measurement Error in Air Pollution Studies: The Impact of Shared, Multiplicative Measurement Error on Epidemiological Health Risk Estimates Air Qual Atmos Health. 2020 Jun; 13(6):631-643. . View in PubMed

Association Between Outdoor Air Pollution and Risk of Malignant and Benign Brain Tumors: The Multiethnic Cohort Study JNCI Cancer Spectr. 2020 Apr; 4(2):pkz107. . View in PubMed

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci Mol Psychiatry. 2020 10; 25(10):2392-2409. . View in PubMed

Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States JCO Oncol Pract. 2020 10; 16(10):e1169-e1180. . View in PubMed

Estrogen Plus Progestin Hormone Therapy and Ovarian Cancer: A Complicated Relationship Explored Epidemiology. 2020 05; 31(3):402-408. . View in PubMed

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study PLoS Genet. 2020 03; 16(3):e1008684. . View in PubMed

Radiation Treatment, ATM, BRCA1/2, and CHEK2*1100delC Pathogenic Variants and Risk of Contralateral Breast Cancer J Natl Cancer Inst. 2020 12 14; 112(12):1275-1279. . View in PubMed

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women Nat Commun. 2020 07 31; 11(1):3833. . View in PubMed

Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Summary Bias Assessment and Meta-Analysis J Natl Cancer Inst Monogr. 2020 07 01; 2020(56):188-200. . View in PubMed

Issues in Interpreting Epidemiologic Studies of Populations Exposed to Low-Dose, High-Energy Photon Radiation J Natl Cancer Inst Monogr. 2020 07 01; 2020(56):176-187. . View in PubMed

Association between ambient air pollution and breast cancer risk: The multiethnic cohort study Int J Cancer. 2020 02 01; 146(3):699-711. . View in PubMed

Urinary N7-(1-hydroxy-3-buten-2-yl) guanine adducts in humans: temporal stability and association with smoking Mutagenesis. 2020 02 13; 35(1):19-26. . View in PubMed

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry Blood Adv. 2020 01 14; 4(1):181-190. . View in PubMed

Interethnic differences in pancreatic cancer incidence and risk factors: The Multiethnic Cohort Cancer Med. 2019 07; 8(7):3592-3603. . View in PubMed

Genetic analyses of diverse populations improves discovery for complex traits Nature. 2019 06; 570(7762):514-518. . View in PubMed

Exposure measurement error in air pollution studies: A framework for assessing shared, multiplicative measurement error in ensemble learning estimates of nitrogen oxides Environ Int. 2019 04; 125:97-106. . View in PubMed

Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic GroupsGastroenterology. 2019 03; 156(4):966-975. e10. . View in PubMed

Association between mitochondrial genetic variation and breast cancer risk: The Multiethnic Cohort PLoS One. 2019; 14(10):e0222284. . View in PubMed

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer JAMA Netw Open. 2019 09 04; 2(9):e1912259. . View in PubMed

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update J Natl Cancer Inst. 2019 08 01; 111(8):811-819. . View in PubMed

Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort J Natl Cancer Inst. 2019 01 01; 111(1):27-33. . View in PubMed

Growth factor genes and change in mammographic density after stopping combined hormone therapy in the California Teachers Study BMC Cancer. 2018 Nov 06; 18(1):1072. . View in PubMed

Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI Int J Obes (Lond). 2018 03; 42(3):384-390. . View in PubMed

Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci Pharmacogenet Genomics. 2018 02; 28(2):49-55. . View in PubMed

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers NPJ Precis Oncol. 2018; 2:17. . View in PubMed

Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations Clin Epigenetics. 2018 08 23; 10(1):110. . View in PubMed

Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study J Clin Oncol. 2018 05 20; 36(15):1513-1520. . View in PubMed

Exome chip analyses identify genes affecting mortality after HLA-matched unrelated-donor blood and marrow transplantation Blood. 2018 05 31; 131(22):2490-2499. . View in PubMed

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation Nat Commun. 2018 04 10; 9:16193. . View in PubMed

Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort Front Cardiovasc Med. 2018; 5:19. . View in PubMed

Sex and ethnic/racial-specific risk factors for gallbladder disease BMC Gastroenterol. 2017 Dec 08; 17(1):153. . View in PubMed

Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex Blood Adv. 2017 Sep 12; 1(20):1717-1728. . View in PubMed

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis PLoS Med. 2017 Sep; 14(9):e1002383. . View in PubMed

Estimates of Radiation Effects on Cancer Risks in the Mayak Worker, Techa River and Atomic Bomb Survivor Studies Radiat Prot Dosimetry. 2017 Apr 01; 173(1-3):26-31. . View in PubMed

THE GROWTH OF BIOSTATISTICS AND ESTIMATION OF CANCER RISK ESTIMATES: PAST, CURRENT, AND FUTURE CHALLENGES Radiat Prot Dosimetry. 2017 Apr 01; 173(1-3):32-35. . View in PubMed

Coffee Drinking and Alcoholic and Nonalcoholic Fatty Liver Diseases and Viral Hepatitis in the Multiethnic Cohort Clin Gastroenterol Hepatol. 2017 08; 15(8):1305-1307. . View in PubMed

Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1034-1042. . View in PubMed

Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1016-1026. . View in PubMed

Mortality from solid cancers other than lung, liver, and bone in relation to external dose among plutonium and non-plutonium workers in the Mayak Worker Cohort Radiat Environ Biophys. 2017 03; 56(1):121-125. . View in PubMed

Association of Common Genetic Variants With Contralateral Breast Cancer Risk in the WECARE Study J Natl Cancer Inst. 2017 10 01; 109(10). . View in PubMed

Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant Blood. 2017 09 28; 130(13):1585-1596. . View in PubMed

Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans Int J Cancer. 2017 06 15; 140(12):2728-2733. . View in PubMed

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study PLoS One. 2017; 12(5):e0178435. . View in PubMed

Association analysis identifies 65 new breast cancer risk loci Nature. 2017 11 02; 551(7678):92-94. . View in PubMed

Correction of confidence intervals in excess relative risk models using Monte Carlo dosimetry systems with shared errors PLoS One. 2017; 12(4):e0174641. . View in PubMed

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry J Natl Cancer Inst. 2017 08 01; 109(8). . View in PubMed

Multi-SNP Haplotype Analysis Methods for Association Analysis Methods Mol Biol. 2017; 1666:485-504. . View in PubMed

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer Cancer Res. 2017 06 01; 77(11):2789-2799. . View in PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer Int J Cancer. 2016 Dec 15; 139(12):2646-2654. . View in PubMed

Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States JAMA Oncol. 2016 Oct 01; 2(10):1295-1302. . View in PubMed

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24 J Natl Cancer Inst. 2016 Jul; 108(7). . View in PubMed

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation Nat Commun. 2016 Apr 07; 7:10979. . View in PubMed

Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity Carcinogenesis. 2016 Mar; 37(3):269-279. . View in PubMed

Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk Hum Mol Genet. 2016 Jan 15; 25(2):371-81. . View in PubMed

Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort Hepatology. 2016 12; 64(6):1969-1977. . View in PubMed

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1609-1618. . View in PubMed

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types Cancer Discov. 2016 09; 6(9):1052-67. . View in PubMed

No Association between the Mitochondrial Genome and Prostate Cancer Risk: The Multiethnic Cohort Cancer Epidemiol Biomarkers Prev. 2016 06; 25(6):1001-3. . View in PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk Obstet Gynecol. 2016 05; 127(5):828-836. . View in PubMed

Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer PLoS One. 2016; 11(6):e0156203. . View in PubMed

Meta-Analysis of Rare Variant Association Tests in Multiethnic Populations Genet Epidemiol. 2016 Jan; 40(1):57-65. . View in PubMed

Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer Nat Genet. 2016 Jan; 48(1):101. . View in PubMed

Benzene Uptake and Glutathione S-transferase T1 Status as Determinants of S-Phenylmercapturic Acid in Cigarette Smokers in the Multiethnic Cohort PLoS One. 2016; 11(3):e0150641. . View in PubMed

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs) Sci Rep. 2016 09 07; 6:32512. . View in PubMed

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk Cancer Res. 2016 10 01; 76(19):5768-5776. . View in PubMed

Associations Between Genetic Ancestries and Nicotine Metabolism Biomarkers in the Multiethnic Cohort Study Am J Epidemiol. 2015 Dec 01; 182(11):945-51. . View in PubMed

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium Clin Cancer Res. 2015 Dec 01; 21(23):5264-76. . View in PubMed

ABO blood group alleles and prostate cancer risk: Results from the breast and prostate cancer cohort consortium (BPC3) Prostate. 2015 Nov; 75(15):1677-81. . View in PubMed

Pleiotropic analysis of cancer risk loci on esophageal adenocarcinoma risk Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1801-3. . View in PubMed

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions Hum Mol Genet. 2015 Oct 01; 24(19):5603-18. . View in PubMed

Atopic allergic conditions and colorectal cancer risk in the Multiethnic Cohort Study Am J Epidemiol. 2015 Jun 01; 181(11):889-97. . View in PubMed

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q312. Hum Mol Genet. 2015 May 15; 24(10):2966-84. . View in PubMed

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer Nat Genet. 2015 Apr; 47(4):373-80. . View in PubMed

Population distribution of lifetime risk of ovarian cancer in the United States Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24(4):671-676. . View in PubMed

Vitamin D-associated genetic variation and risk of breast cancer in the breast and prostate cancer cohort consortium (BPC3) Cancer Epidemiol Biomarkers Prev. 2015 Mar; 24(3):627-30. . View in PubMed

Generalizability of established prostate cancer risk variants in men of African ancestry Int J Cancer. 2015 Mar 01; 136(5):1210-7. . View in PubMed

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study Gynecol Oncol. 2015 Mar; 136(3):542-8. . View in PubMed

Variation in levels of the lung carcinogen NNAL and its glucuronides in the urine of cigarette smokers from five ethnic groups with differing risks for lung cancer Cancer Epidemiol Biomarkers Prev. 2015 Mar; 24(3):561-9. . View in PubMed

Dose reconstruction for the million worker study: status and guidelines Health Phys. 2015 Feb; 108(2):206-20. . View in PubMed

Fine-scale mapping of the 5q112 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. Am J Hum Genet. 2015 Jan 08; 96(1):5-20. . View in PubMed

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation Nat Genet. 2015 11; 47(11):1282-1293. . View in PubMed

Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer PLoS One. 2015; 10(6):e0124841. . View in PubMed

The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1):119-27. . View in PubMed

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk Hum Mol Genet. 2015 Jan 01; 24(1):285-98. . View in PubMed

Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort PLoS One. 2015; 10(9):e0136796. . View in PubMed

Shared dosimetry error in epidemiological dose-response analyses PLoS One. 2015; 10(3):e0119418. . View in PubMed

Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults PLoS One. 2015; 10(6):e0131106. . View in PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p1533. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. . View in PubMed

High calorie intake is associated with worsening insulin resistance and ß-cell function in Hispanic women after gestational diabetes mellitus Diabetes Care. 2014 Dec; 37(12):3294-300. . View in PubMed

Diabetes and racial/ethnic differences in hepatocellular carcinoma risk: the multiethnic cohort J Natl Cancer Inst. 2014 Dec; 106(12). . View in PubMed

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium Hum Mol Genet. 2014 Nov 15; 23(22):6096-111. . View in PubMed

Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium Am J Epidemiol. 2014 Nov 15; 180(10):1018-27. . View in PubMed

Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups Carcinogenesis. 2014 Nov; 35(11):2526-33. . View in PubMed

A comprehensive examination of breast cancer risk loci in African American women Hum Mol Genet. 2014 Oct 15; 23(20):5518-26. . View in PubMed

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer Nat Genet. 2014 Oct; 46(10):1103-9. . View in PubMed

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation Nat Commun. 2014 Sep 23; 4:4999. . View in PubMed

Fine-mapping IGF1 and prostate cancer risk in African Americans: the multiethnic cohort study Cancer Epidemiol Biomarkers Prev. 2014 Sep; 23(9):1928-32. . View in PubMed

The role of local ancestry adjustment in association studies using admixed populations Genet Epidemiol. 2014 Sep; 38(6):502-15. . View in PubMed

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A Nat Commun. 2014 Aug 08; 5:4613. . View in PubMed

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians Diabetes. 2014 Jul; 63(7):2551-62. . View in PubMed

Insulin-like growth factor pathway genetic polymorphisms, circulating IGF1 and IGFBP3, and prostate cancer survival J Natl Cancer Inst. 2014 Jun; 106(6):dju085. . View in PubMed

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium Br J Cancer. 2014 Feb 18; 110(4):1088-100. . View in PubMed

Analysis of cancer risks in populations near nuclear facilities: Phase IA report by the National Academies Nuclear and Radiation Studies Board. Health Phys. 2014 Feb; 106(2):305-6. . View in PubMed

Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study PLoS One. 2014; 9(2):e87762. . View in PubMed

Pleiotropy of cancer susceptibility variants on the risk of non-Hodgkin lymphoma: the PAGE consortium PLoS One. 2014; 9(3):e89791. . View in PubMed

Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans Hum Mol Genet. 2013 Dec 15; 22(24):5048-55. . View in PubMed

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1 Am J Hum Genet. 2013 Dec 05; 93(6):1046-60. . View in PubMed

Dietary patterns and breast cancer risk in the California Teachers Study cohort Am J Clin Nutr. 2013 Dec; 98(6):1524-32. . View in PubMed

Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2094-101. . View in PubMed

Role of aldehydes in the toxic and mutagenic effects of nitrosamines Chem Res Toxicol. 2013 Oct 21; 26(10):1464-73. . View in PubMed

Workshop report on atomic bomb dosimetry-residual radiation exposure: recent research and suggestions for future studies Health Phys. 2013 Aug; 105(2):140-9. . View in PubMed

Late health effects of radiation exposure: new statistical, epidemiological, and biological approaches Int J Radiat Biol. 2013 Aug; 89(8):673-83. . View in PubMed

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls Hum Mol Genet. 2013 Jun 15; 22(12):2539-50. . View in PubMed

Hormone metabolism genes and mammographic density in Singapore Chinese women Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):984-6. . View in PubMed

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):880-90. . View in PubMed

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers Am J Hum Genet. 2013 Apr 04; 92(4):489-503. . View in PubMed

Genome-wide association studies identify four ER negative-specific breast cancer risk loci Nat Genet. 2013 Apr; 45(4):392-8398e1-2. . View in PubMed

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer Nat Genet. 2013 Apr; 45(4):371-84384e1-2. . View in PubMed

Large-scale genotyping identifies 41 new loci associated with breast cancer risk Nat Genet. 2013 Apr; 45(4):353-61361e1-2. . View in PubMed

Genetic variation in transforming growth factor beta 1 and mammographic density in Singapore Chinese women Cancer Res. 2013 Mar 15; 73(6):1876-82. . View in PubMed

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population PLoS Genet. 2013 Mar; 9(3):e1003419. . View in PubMed

Levels of beta-microseminoprotein in blood and risk of prostate cancer in multiple populations J Natl Cancer Inst. 2013 Feb 06; 105(3):237-43. . View in PubMed

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer Nat Commun. 2013; 4:1628. . View in PubMed

A genome-wide scan for breast cancer risk haplotypes among African American women PLoS One. 2013; 8(2):e57298. . View in PubMed

A genome-wide association study of breast cancer in women of African ancestry Hum Genet. 2013 Jan; 132(1):39-48. . View in PubMed

Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium Am J Epidemiol. 2012 Dec 15; 176(12):1121-9. . View in PubMed

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11 Hum Mol Genet. 2012 Dec 15; 21(24):5373-84. . View in PubMed

Evaluating genetic risk for prostate cancer among Japanese and Latinos Cancer Epidemiol Biomarkers Prev. 2012 Nov; 21(11):2048-58. . View in PubMed

Genetic predisposition to radiation-related cancer and potential implications for risk assessment Ann ICRP. 2012 Oct-Dec; 41(3-4):108-16. . View in PubMed

Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies Int J Cancer. 2012 Sep 15; 131(6):E1038-43. . View in PubMed

Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status J Med Genet. 2012 Sep; 49(9):601-8. . View in PubMed

Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese women Cancer Epidemiol Biomarkers Prev. 2012 Apr; 21(4):635-44. . View in PubMed

Common genetic variants in prostate cancer risk prediction--results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3) Cancer Epidemiol Biomarkers Prev. 2012 Mar; 21(3):437-44. . View in PubMed

Regression calibration when foods (measured with error) are the variables of interest: markedly non-Gaussian data with many zeroes Am J Epidemiol. 2012 Feb 15; 175(4):325-31. . View in PubMed

Population genetic structure and origins of Native Hawaiians in the multiethnic cohort study PLoS One. 2012; 7(11):e47881. . View in PubMed

Multi-SNP haplotype analysis methods for association analysis Methods Mol Biol. 2012; 850:423-52. . View in PubMed

Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies Gut. 2011 Dec; 60(12):1703-11. . View in PubMed

Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans Hum Mol Genet. 2011 Nov 15; 20(22):4491-503. . View in PubMed

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer Nat Genet. 2011 Oct 30; 43(12):1210-4. . View in PubMed

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry PLoS Genet. 2011 Oct; 7(10):e1002298. . View in PubMed

Genome-wide association study identifies new prostate cancer susceptibility loci Hum Mol Genet. 2011 Oct 01; 20(19):3867-75. . View in PubMed

No association of type 2 diabetes risk variants and prostate cancer risk: the multiethnic cohort and PAGE Cancer Epidemiol Biomarkers Prev. 2011 Sep; 20(9):1979-81. . View in PubMed

Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium J Natl Cancer Inst. 2011 Aug 17; 103(16):1252-63. . View in PubMed

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk Hum Mol Genet. 2011 Jun 01; 20(11):2263-72. . View in PubMed

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21 Nat Genet. 2011 Jun; 43(6):570-3. . View in PubMed

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing Clin Cancer Res. 2011 Jun 01; 17(11):3742-50. . View in PubMed

Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer Cancer Epidemiol Biomarkers Prev. 2011 May; 20(5):1028-31. . View in PubMed

Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans PLoS Genet. 2011 May; 7(5):e1001387. . View in PubMed

No association of risk variants for diabetes and obesity with breast cancer: the Multiethnic Cohort and PAGE studies Cancer Epidemiol Biomarkers Prev. 2011 May; 20(5):1039-42. . View in PubMed

Diagnostic radiography and adult acute myeloid leukaemia: an interview and medical chart review study Br J Cancer. 2011 Apr 26; 104(9):1482-6. . View in PubMed

Age-specific effects of hormone therapy use on overall mortality and ischemic heart disease mortality among women in the California Teachers Study Menopause. 2011 Mar; 18(3):253-61. . View in PubMed

Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3 PLoS One. 2011 Feb 24; 6(2):e17142. . View in PubMed

Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations Eur J Hum Genet. 2011 Feb; 19(2):243-5. . View in PubMed

Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations Cancer Epidemiol Biomarkers Prev. 2011 Jan; 20(1):70-81. . View in PubMed

Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2877-87. . View in PubMed

Common variants at 19p13 are associated with susceptibility to ovarian cancer Nat Genet. 2010 Oct; 42(10):880-4. . View in PubMed

A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations Cancer Epidemiol Biomarkers Prev. 2010 Oct; 19(10):2639-46. . View in PubMed

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 Nat Genet. 2010 Oct; 42(10):874-9. . View in PubMed

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium Hum Mol Genet. 2010 Oct 01; 19(19):3873-84. . View in PubMed

The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data PLoS Genet. 2010 Sep 02; 6(9):e1001096. . View in PubMed

A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer riskResults from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. J Clin Endocrinol Metab. 2010 Sep; 95(9):E121-7. . View in PubMed

Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups PLoS Genet. 2010 Aug 26; 6(8). . View in PubMed

Self-reported ethnicity, genetic structure and the impact of population stratification in a multiethnic study Hum Genet. 2010 Aug; 128(2):165-77. . View in PubMed

A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians Hum Mol Genet. 2010 Aug 01; 19(15):3089-101. . View in PubMed

Fine mapping of the association with obesity at the FTO locus in African-derived populations Hum Mol Genet. 2010 Jul 15; 19(14):2907-16. . View in PubMed

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot" PLoS Genet. 2010 Jul 08; 6(7):e1001016. . View in PubMed

Meat consumption, nonsteroidal anti-inflammatory drug use, and mortality among colorectal cancer patients in the California Teachers Study Cancer Prev Res (Phila). 2010 Jul; 3(7):865-75. . View in PubMed

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1822-30. . View in PubMed

The association of diabetes with colorectal cancer risk: the Multiethnic Cohort Br J Cancer. 2010 Jun 29; 103(1):120-6. . View in PubMed

Exploring genetic susceptibility to cancer in diverse populations Curr Opin Genet Dev. 2010 Jun; 20(3):330-5. . View in PubMed

Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs J Exp Clin Cancer Res. 2010 May 25; 29:57. . View in PubMed

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer Cancer Res. 2010 Mar 15; 70(6):2389-96. . View in PubMed

PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3) Carcinogenesis. 2010 Mar; 31(3):455-61. . View in PubMed

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):600-4. . View in PubMed

Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort Breast Cancer Res. 2010; 12(1):R4. . View in PubMed

Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis Cancer. 2009 Dec 15; 115(24):5662-71. . View in PubMed

Methodological Issues in Multistage Genome-wide Association Studies Stat Sci. 2009 Nov 01; 24(4):414-429. . View in PubMed

Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3) Hum Mol Genet. 2009 Oct 01; 18(19):3749-57. . View in PubMed

CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the Breast and Prostate Cancer Cohort Consortium Cancer Epidemiol Biomarkers Prev. 2009 Oct; 18(10):2734-44. . View in PubMed

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p222. Nat Genet. 2009 Sep; 41(9):996-1000. . View in PubMed

Genetic polymorphisms of the GNRH1 and GNRHR genes and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) BMC Cancer. 2009 Jul 29; 9:257. . View in PubMed

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study Hum Mol Genet. 2009 Jun 15; 18(12):2297-304. . View in PubMed

A kinship-based modification of the armitage trend test to address hidden population structure and small differential genotyping errors PLoS One. 2009 Jun 08; 4(6):e5825. . View in PubMed

IGF2R missense single-nucleotide polymorphisms and breast cancer risk: the multiethnic cohort study Cancer Epidemiol Biomarkers Prev. 2009 Jun; 18(6):1922-4. . View in PubMed

Association of diabetes with prostate cancer risk in the multiethnic cohort Am J Epidemiol. 2009 Apr 15; 169(8):937-45. . View in PubMed

Generalizability of associations from prostate cancer genome-wide association studies in multiple populations Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1285-9. . View in PubMed

Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium Cancer Epidemiol Biomarkers Prev. 2009 Jan; 18(1):297-305. . View in PubMed

Dietary assessment in the California Teachers Study: reproducibility and validity Cancer Causes Control. 2008 Aug; 19(6):595-603. . View in PubMed

IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3) PLoS One. 2008 Jul 02; 3(7):e2578. . View in PubMed

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics PLoS Genet. 2008 Apr 25; 4(4):e1000054. . View in PubMed

Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations Hum Mol Genet. 2008 Mar 15; 17(6):825-34. . View in PubMed

Comprehensive evaluation of ESR2 variation and ovarian cancer risk Cancer Epidemiol Biomarkers Prev. 2008 Feb; 17(2):393-6. . View in PubMed

Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis Br J Cancer. 2008 Jan 29; 98(2):282-8. . View in PubMed

Haplotypes of the estrogen receptor beta gene and breast cancer risk Int J Cancer. 2008 Jan 15; 122(2):387-92. . View in PubMed

Relationship of serological subtype, basic core promoter and precore mutations to genotypes/subgenotypes of hepatitis B virus J Med Virol. 2008 Jan; 80(1):27-46. . View in PubMed

Dietary patterns and risk of ovarian cancer in the California Teachers Study cohort Nutr Cancer. 2008; 60(3):285-91. . View in PubMed

Utilizing HapMap and tagging SNPs Methods Mol Med. 2008; 141:37-54. . View in PubMed

A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort BMC Med Genet. 2007 Dec 01; 8:72. . View in PubMed

Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study Am J Epidemiol. 2007 Dec 01; 166(11):1259-69. . View in PubMed

A Monte Carlo maximum likelihood method for estimating uncertainty arising from shared errors in exposures in epidemiological studies of nuclear workers Radiat Res. 2007 Dec; 168(6):757-63. . View in PubMed

CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2237-46. . View in PubMed

Risk factors for renal cell cancer: the multiethnic cohort Am J Epidemiol. 2007 Oct 15; 166(8):932-40. . View in PubMed

Re: the use of inferred haplotypes in downstream analysis Am J Hum Genet. 2007 Oct; 81(4):863-5; author reply 865-6. . View in PubMed

Hypothesis testing, statistical power, and confidence limits in the presence of epistemic uncertainty Health Phys. 2007 Oct; 93(4):326-7; author reply 327-8. . View in PubMed

Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):1973-81. . View in PubMed

Dietary fiber and colorectal cancer risk: the multiethnic cohort study Cancer Causes Control. 2007 Sep; 18(7):753-64. . View in PubMed

A common genetic risk factor for colorectal and prostate cancer Nat Genet. 2007 Aug; 39(8):954-6. . View in PubMed

Multiple regions within 8q24 independently affect risk for prostate cancer Nat Genet. 2007 May; 39(5):638-44. . View in PubMed

A common 8q24 variant in prostate and breast cancer from a large nested case-control study Cancer Res. 2007 Apr 01; 67(7):2951-6. . View in PubMed

Diet and risk of ovarian cancer in the California Teachers Study cohort Am J Epidemiol. 2007 Apr 01; 165(7):802-13. . View in PubMed

Physical activity and colon cancer risk among women in the California Teachers Study Cancer Epidemiol Biomarkers Prev. 2007 Mar; 16(3):517-25. . View in PubMed

Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women Cancer Res. 2007 Mar 01; 67(5):1893-7. . View in PubMed

Long-term recreational physical activity and risk of invasive and in situ breast cancer: the California teachers study Arch Intern Med. 2007 Feb 26; 167(4):408-15. . View in PubMed

Wine and other alcohol consumption and risk of ovarian cancer in the California Teachers Study cohort Cancer Causes Control. 2007 Feb; 18(1):91-103. . View in PubMed

Beta-cryptoxanthin and lung cancer in Shanghai, China--an examination of potential confounding with cigarette smoking using urinary cotinine as a biomarker for true tobacco exposure Nutr Cancer. 2007; 57(2):123-9. . View in PubMed

Exploiting gene-environment interaction to detect genetic associations Hum Hered. 2007; 63(2):111-9. . View in PubMed

A systematic assessment of common genetic variation in CYP11A and risk of breast cancer Cancer Res. 2006 Dec 15; 66(24):12019-25. . View in PubMed

An utter refutation of the "Fundamental Theorem of the HapMap" by Terwilliger and Hiekkalinna Eur J Hum Genet. 2006 Dec; 14(12):1238-9. . View in PubMed

Prostate cancer incidence and intake of fruits, vegetables and related micronutrients: the multiethnic cohort study* (United States) Cancer Causes Control. 2006 Nov; 17(9):1193-207. . View in PubMed

Transferability of tag SNPs in genetic association studies in multiple populations Nat Genet. 2006 Nov; 38(11):1298-303. . View in PubMed

Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1993-7. . View in PubMed

Asparagine depletion after pegylated Ecoli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941). Pediatr Blood Cancer. 2006 Aug; 47(2):141-6. . View in PubMed

Bone marrow transplantation versus prolonged intensive chemotherapy for children with acute lymphoblastic leukemia and an initial bone marrow relapse within 12 months of the completion of primary therapy: Children's Oncology Group study CCG-1941 J Clin Oncol. 2006 Jul 01; 24(19):3150-6. . View in PubMed

Common genetic variation at PTEN and risk of sporadic breast and prostate cancer Cancer Epidemiol Biomarkers Prev. 2006 May; 15(5):1021-5. . View in PubMed

Optimal two-stage genotyping designs for genome-wide association scans Genet Epidemiol. 2006 May; 30(4):356-68. . View in PubMed

Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies Cancer Res. 2006 Feb 15; 66(4):2468-75. . View in PubMed

Ethnic and racial differences in the smoking-related risk of lung cancer N Engl J Med. 2006 Jan 26; 354(4):333-42. . View in PubMed

Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort J Natl Cancer Inst. 2006 Jan 18; 98(2):123-34. . View in PubMed

A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3) Breast Cancer Res. 2006; 8(5):R54. . View in PubMed

Igf-I genetic variation and breast cancer: the multiethnic cohort Cancer Epidemiol Biomarkers Prev. 2006 Jan; 15(1):172-4. . View in PubMed

Genetic variation in the HSD17B1 gene and risk of prostate cancer PLoS Genet. 2005 Nov; 1(5):e68. . View in PubMed

Asymptotic equivalence between two score tests for haplotype-specific risk in general linear models Genet Epidemiol. 2005 Sep; 29(2):166-70. . View in PubMed

A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk Cancer Res. 2005 Aug 15; 65(16):7516-22. . View in PubMed

Designs for studies of personal exposure to air pollution and the impact of measurement error J Toxicol Environ Health A. 2005 Jul 9-23; 68(13-14):1181-7. . View in PubMed

Comparison of prostate-specific antigen and hormone levels among men in Singapore and the United States Cancer Epidemiol Biomarkers Prev. 2005 Jul; 14(7):1692-6. . View in PubMed

Nonsteroidal anti-inflammatory drug use and breast cancer risk by stage and hormone receptor status J Natl Cancer Inst. 2005 Jun 01; 97(11):805-12. . View in PubMed

Software for tag single nucleotide polymorphism selection Hum Genomics. 2005 Jun; 2(2):144-51. . View in PubMed

BRCA1 variants in a family study of African-American and Latina women Hum Genet. 2005 May; 116(6):497-506. . View in PubMed

A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women Am J Clin Nutr. 2005 May; 81(5):1133-41. . View in PubMed

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis J Natl Cancer Inst. 2005 Jan 05; 97(1):51-9. . View in PubMed

A candidate gene approach to searching for low-penetrance breast and prostate cancer genes Nat Rev Cancer. 2005 12; 5(12):977-85. . View in PubMed

Enlarged and prominent nucleoli may be indicative of MYCN amplification: a study of neuroblastoma (Schwannian stroma-poor), undifferentiated/poorly differentiated subtype with high mitosis-karyorrhexis index Cancer. 2005 Jan 01; 103(1):174-80. . View in PubMed

Tag SNP selection for association studies Genet Epidemiol. 2004 Dec; 27(4):365-74. . View in PubMed

Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort Hum Mol Genet. 2004 Oct 15; 13(20):2431-41. . View in PubMed

Revision of the International Neuroblastoma Pathology Classification: confirmation of favorable and unfavorable prognostic subsets in ganglioneuroblastoma, nodular Cancer. 2003 Nov 15; 98(10):2274-81. . View in PubMed

A comprehensive haplotype analysis of CYP19 and breast cancer risk: the Multiethnic Cohort Hum Mol Genet. 2003 Oct 15; 12(20):2679-92. . View in PubMed

Power and uncertainty analysis of epidemiological studies of radiation-related disease risk in which dose estimates are based on a complex dosimetry system: some observations Radiat Res. 2003 Oct; 160(4):408-17. . View in PubMed

Dietary cryptoxanthin and reduced risk of lung cancer: the Singapore Chinese Health Study Cancer Epidemiol Biomarkers Prev. 2003 Sep; 12(9):890-8. . View in PubMed

Re: Beta-carotene and lung cancer: a lesson for future chemoprevention investigations? J Natl Cancer Inst. 2003 May 21; 95(10):E4.. View in PubMed

Impact of radiotherapy for high-risk neuroblastoma: a Children's Cancer Group study Int J Radiat Oncol Biol Phys. 2003 May 01; 56(1):28-39. . View in PubMed

Correlation of dietary intake and colorectal cancer incidence among Mexican-American migrants: the multiethnic cohort study Nutr Cancer. 2003; 45(2):133-47. . View in PubMed

Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals Hum Hered. 2003; 55(4):179-90. . View in PubMed

Bayesian spatial modeling of haplotype associations Hum Hered. 2003; 56(1-3):32-40. . View in PubMed

Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study Hum Hered. 2003; 55(1):27-36. . View in PubMed

Breast cancer in a multiethnic cohort in Hawaii and Los Angeles: risk factor-adjusted incidence in Japanese equals and in Hawaiians exceeds that in whites Cancer Epidemiol Biomarkers Prev. 2002 Sep; 11(9):795-800. . View in PubMed

Association between air pollution and lung function growth in southern California children: results from a second cohort Am J Respir Crit Care Med. 2002 Jul 01; 166(1):76-84. . View in PubMed

Breast-feeding and neuroblastoma, USA and Canada Cancer Causes Control. 2002 Jun; 13(5):401-5. . View in PubMed

Is residual confounding a reasonable explanation for the apparent protective effects of beta-carotene found in epidemiologic studies of lung cancer in smokers? Am J Epidemiol. 2002 Apr 01; 155(7):622-8.. View in PubMed

Risk factors for cardiovascular and cerebrovascular death among African Americans and Hispanics in Los Angeles, California Acad Emerg Med. 2001 Dec; 8(12):1163-72. . View in PubMed

Histopathology (International Neuroblastoma Pathology Classification) and MYCN status in patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group Cancer. 2001 Nov 15; 92(10):2699-708. . View in PubMed

Regression calibration in studies with correlated variables measured with error Am J Epidemiol. 2001 Nov 01; 154(9):836-44. . View in PubMed

International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group Cancer. 2001 Nov 01; 92(9):2451-61. . View in PubMed

Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: clinical outcome and antineuronal antibodies-a report from the Children's Cancer Group Study Med Pediatr Oncol. 2001 Jun; 36(6):612-22. . View in PubMed

Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: histopathologic features-a report from the Children's Cancer Group Med Pediatr Oncol. 2001 Jun; 36(6):623-9. . View in PubMed

Duration of hospitalization as a measure of cost on Children's Cancer Group acute lymphoblastic leukemia studies J Clin Oncol. 2001 Apr 01; 19(7):1916-25. . View in PubMed

Building a multigenic model of breast cancer susceptibility: CYP17 and HSD17B1 are two important candidates Cancer Res. 2001 Jan 15; 61(2):785-9. . View in PubMed

Loss of heterozygosity for chromosome 14q in neuroblastoma Med Pediatr Oncol. 2001 Jan; 36(1):28-31. . View in PubMed

Allelic deletion at chromosome bands 11q14-23 is common in neuroblastoma Med Pediatr Oncol. 2001 Jan; 36(1):24-7. . View in PubMed

Comprehensive analysis of chromosome 1p deletions in neuroblastoma Med Pediatr Oncol. 2001 Jan; 36(1):32-6. . View in PubMed

Bone marrow leukemic progenitor cell content in pediatric T-lineage acute lymphoblastic leukemia patients with an isolated extramedullary first relapse Leuk Lymphoma. 2001 Jan; 40(3-4):279-85. . View in PubMed

Singapore Chinese Health Study: development, validation, and calibration of the quantitative food frequency questionnaire Nutr Cancer. 2001; 39(2):187-95. . View in PubMed

Quantitative tumor cell content of bone marrow and blood as a predictor of outcome in stage IV neuroblastoma: a Children's Cancer Group Study J Clin Oncol. 2000 Dec 15; 18(24):4067-76. . View in PubMed

Deletion of 11q23 is a frequent event in the evolution of MYCN single-copy high-risk neuroblastomas Med Pediatr Oncol. 2000 Dec; 35(6):544-6. . View in PubMed

Multidrug resistance-associated protein 1 (MRP1) expression in neuroblastoma cell lines and primary tumors Med Pediatr Oncol. 2000 Dec; 35(6):619-22. . View in PubMed

Correcting for exposure measurement error in uranium miners studies: impact on inverse dose-rate effects Radiat Res. 2000 Dec; 154(6):738-9;discussion 739-40. . View in PubMed

Histopathology defines prognostic subsets of ganglioneuroblastoma, nodular Cancer. 2000 Sep 01; 89(5):1150-61. . View in PubMed

Antineuronal antibodies in patients with neuroblastoma and paraneoplastic opsoclonus-myoclonus J Pediatr Hematol Oncol. 2000 Jul-Aug; 22(4):315-20. . View in PubMed

Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study J Clin Oncol. 2000 May; 18(9):1888-99. . View in PubMed

Biologic factors determine prognosis in infants with stage IV neuroblastoma: A prospective Children's Cancer Group study J Clin Oncol. 2000 Mar; 18(6):1260-8. . View in PubMed

A multiethnic cohort in Hawaii and Los Angeles: baseline characteristics Am J Epidemiol. 2000 Feb 15; 151(4):346-57. . View in PubMed

Calibration of the dietary questionnaire for a multiethnic cohort in Hawaii and Los Angeles Am J Epidemiol. 2000 Feb 15; 151(4):358-70. . View in PubMed

Favorable biology and outcome of stage IV-S neuroblastoma with supportive care or minimal therapy: a Children's Cancer Group study J Clin Oncol. 2000 Feb; 18(3):477-86. . View in PubMed

Biologic variables in the outcome of stages I and II neuroblastoma treated with surgery as primary therapy: a children's cancer group study J Clin Oncol. 2000 Jan; 18(1):18-26. . View in PubMed

Neuroblastoma and parental occupation Cancer Causes Control. 1999 Dec; 10(6):539-49. . View in PubMed

Hormone and fertility drug use and the risk of neuroblastoma: a report from the Children's Cancer Group and the Pediatric Oncology Group Am J Epidemiol. 1999 Nov 01; 150(9):930-8. . View in PubMed

Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acidChildren's Cancer Group. N Engl J Med. 1999 Oct 14; 341(16):1165-73. . View in PubMed

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas Oncogene. 1999 Sep 02; 18(35):4948-57. . View in PubMed

Paucity of leukemic progenitor cells in the bone marrow of pediatric B-lineage acute lymphoblastic leukemia patients with an isolated extramedullary first relapse Clin Cancer Res. 1999 Sep; 5(9):2415-20. . View in PubMed

Correcting for exposure measurement error in a reanalysis of lung cancer mortality for the Colorado Plateau Uranium Miners cohort Health Phys. 1999 Sep; 77(3):265-75. . View in PubMed

The International Neuroblastoma Pathology Classification (the Shimada system) Cancer. 1999 Jul 15; 86(2):364-72. . View in PubMed

A strategic view of randomized trial design in low-incidence paediatric cancer Stat Med. 1999 May 30; 18(10):1183-97. . View in PubMed

Metastatic sites in stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival J Pediatr Hematol Oncol. 1999 May-Jun; 21(3):181-9. . View in PubMed

Meta-analysis: dietary fat intake, serum estrogen levels, and the risk of breast cancer J Natl Cancer Inst. 1999 Mar 17; 91(6):529-34. . View in PubMed

Re: "Associations of race/ethnicity, education, and dietary intervention with the validity and reliability of a food frequency questionnaireThe Women's Health Trial Feasibility Study in Minority Populations". Am J Epidemiol. 1998 Oct 15; 148(8):819-20. . View in PubMed

Successful treatment of stage III neuroblastoma based on prospective biologic staging: a Children's Cancer Group study J Clin Oncol. 1998 Apr; 16(4):1256-64. . View in PubMed

Role of viral load in heterosexual transmission of human immunodeficiency virus type 1 by blood transfusion recipientsTransfusion Safety Study Group. Am J Epidemiol. 1997 Oct 15; 146(8):655-61. . View in PubMed

Influences of age, viral load, and CD4+ count on the rate of progression of HIV-1 infection to AIDSTransfusion Safety Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Jul 01; 15(3):243-4. . View in PubMed

Comparative rates of disease progression among persons infected with the same or different HIV-1 strainsThe Transfusion Safety Study Group. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Jun 01; 15(2):145-50. . View in PubMed

Neuroblastoma in adults and adolescents: an indolent course with poor survival Cancer. 1997 May 15; 79(10):2028-35. . View in PubMed

Analysis of time to death after transplantation when transplants are only given to patients in remission Biometrics. 1996 Sep; 52(3):1079-86. . View in PubMed

Consolidation chemoradiotherapy and autologous bone marrow transplantation versus continued chemotherapy for metastatic neuroblastoma: a report of two concurrent Children's Cancer Group studies J Clin Oncol. 1996 Sep; 14(9):2417-26. . View in PubMed

Donor levels of serum alanine aminotransferase activity and antibody to hepatitis B core antigen associated with recipient hepatitis C and non-B, non-C outcomes Transfusion. 1996 Sep; 36(9):776-81. . View in PubMed

Use of selenium concentration in whole blood, serum, toenails, or urine as a surrogate measure of selenium intake Epidemiology. 1996 Jul; 7(4):384-90. . View in PubMed

Factors influencing human immunodeficiency virus type 1 transmission by blood transfusionTransfusion Safety Study Group. J Infect Dis. 1996 Jul; 174(1):26-33. . View in PubMed

Meta-analysis of published data using a linear mixed-effects model Biometrics. 1996 Jun; 52(2):536-44. . View in PubMed

Segregation analysis of continuous phenotypes by using higher sample moments Am J Hum Genet. 1996 Jan; 58(1):213-24. . View in PubMed

Pelvic neuroblastoma--implications for a new favorable subgroup: a Children's Cancer Group experience Ann Surg Oncol. 1995 Nov; 2(6):516-23. . View in PubMed

Identification of subsets of neuroblastomas by combined histopathologic and N-myc analysis J Natl Cancer Inst. 1995 Oct 04; 87(19):1470-6. . View in PubMed

Human immunodeficiency virus type 1 infection: relationship of risk group and age to rate of progression to AIDSTransfusion Safety Study Group. J Infect Dis. 1995 Sep; 172(3):648-55. . View in PubMed

Cost-efficient design of a diet validation study Am J Epidemiol. 1995 Aug 01; 142(3):353-62. . View in PubMed

Surgical management and outcome of locoregional neuroblastoma: comparison of the Childrens Cancer Group and the international staging systems J Pediatr Surg. 1995 Feb; 30(2):289-94; discussion 295. . View in PubMed

Role of myeloablative therapy in improved outcome for high risk neuroblastoma: review of recent Children's Cancer Group results Eur J Cancer. 1995; 31A(4):572-5. . View in PubMed

Variance components testing in the longitudinal mixed effects model Biometrics. 1994 Dec; 50(4):1171-7. . View in PubMed

Allogeneic versus autologous purged bone marrow transplantation for neuroblastoma: a report from the Childrens Cancer Group J Clin Oncol. 1994 Nov; 12(11):2382-9. . View in PubMed

Treatment of overt isolated testicular relapse in children on therapy for acute lymphoblastic leukemiaA report from the Childrens Cancer Group. Cancer. 1994 Jan 01; 73(1):219-23. . View in PubMed

Comparison of autologous and allogeneic bone marrow transplantation for neuroblastoma Prog Clin Biol Res. 1994; 385:301-7. . View in PubMed

Myeloablative chemoradiotherapy versus continued chemotherapy for high risk neuroblastoma Prog Clin Biol Res. 1994; 385:287-91. . View in PubMed

Patterns of relapse after autologous purged bone marrow transplantation for neuroblastoma: a Childrens Cancer Group pilot study J Clin Oncol. 1993 Nov; 11(11):2226-33. . View in PubMed

Stable chromosome aberrations among A-bomb survivors: an update Radiat Res. 1993 Oct; 136(1):29-36. . View in PubMed

A generalized estimating equations approach to fitting major gene models in segregation analysis of continuous phenotypes Genet Epidemiol. 1993; 10(1):61-74. . View in PubMed

Use of generalized estimating equations in segregation analysis of continuous outcomes Genet Epidemiol. 1993; 10(6):575-9. . View in PubMed

An estimate of the magnitude of random errors in the DS86 dosimetry from data on chromosome aberrations and severe epilation Radiat Res. 1991 Nov; 128(2):157-69. . View in PubMed

Aggressive surgery combined with intensive chemotherapy improves survival in poor-risk neuroblastoma J Pediatr Surg. 1991 Sep; 26(9):1119-23; discussion 1123-4. . View in PubMed

Recent uses of biological data for the evaluation of A-bomb radiation dosimetry J Radiat Res. 1991 Mar; 32 Suppl:122-35. . View in PubMed

Allowing for dose-estimation errors for the A-bomb survivor data J Radiat Res. 1991 Mar; 32 Suppl:108-21. . View in PubMed

The observed relationship between the occurrence of acute radiation effects and leukemia mortality among A-bomb survivors Radiat Res. 1991 Feb; 125(2):206-13. . View in PubMed

Allowing for random errors in radiation dose estimates for the atomic bomb survivor data Radiat Res. 1990 Sep; 123(3):275-84. . View in PubMed

Smoking and serum proteins in atomic-bomb survivors in Japan Am J Epidemiol. 1990 Jun; 131(6):1038-45. . View in PubMed

Effects of inhalable particles on respiratory health of children Am Rev Respir Dis. 1989 Mar; 139(3):587-94. . View in PubMed

Analysis of the DS86 atomic bomb radiation dosimetry methods using data on severe epilation Radiat Res. 1989 Jan; 117(1):93-113. . View in PubMed

Analysing repeated measurements with possibly missing observations by modelling marginal distributions Stat Med. 1988 Jan-Feb; 7(1-2):139-48. . View in PubMed

My research is on general biostatistical issues in epidemiology, and I am a long time collaborator on a number of important prospective (cohort) studies of cancer and other diseases. These include the Atomic Bomb Survivors Study, the Multiethnic Cohort Study, and the Children's Health Study. I participate in many other projects in the Preventive Medicine Department at USC. I have particular interest in measurement error issues in dosimetry for radiation epidemiology and in dietary assessment for nutritional epidemiology. I have recently begun working on association-based testing for the influence upon cancer risk of genomic variation in candidate genes using nested case-control studies within the MEC, with special emphasis on haplotype-based risk estimation and haplotype-tagging SNP selection. See the publications and software development list below, for further information.
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