Keck School Faculty

Danny J Wang

Danny J Wang

Professor of Neurology and Radiology
SHN, 2025 Zonal Ave. Health Sciences Campus Los Angeles

Vessel Density Mapping of Cerebral Small Vessels on 3D High Resolution Black Blood MRI bioRxiv. 2023 Mar 21. . View in PubMed

Decreased water exchange rate across blood-brain barrier in hereditary cerebral small vessel disease Brain. 2023 Jan 10. . View in PubMed

Depression, stress, and regional cerebral blood flow J Cereb Blood Flow Metab. 2023 Jan 06; 271678X221148979. . View in PubMed

Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging Magn Reson Med. 2023 05; 89(5):2024-2047. . View in PubMed

Quantification of blood-brain barrier water exchange and permeability with multidelay diffusion-weighted pseudo-continuous arterial spin labeling Magn Reson Med. 2023 05; 89(5):1990-2004. . View in PubMed

Editorial for "Arterial Spin Labeling Estimation of Penumbral Tissue in Acute Ischemic Stroke" J Magn Reson Imaging. 2023 04; 57(4):1248-1249. . View in PubMed

Older Adults With Higher Blood Pressure Variability Exhibit Cerebrovascular Reactivity Deficits Am J Hypertens. 2023 01 01; 36(1):63-68. . View in PubMed

Sex differences in frontotemporal atrophy in CADASIL revealed by 7-Tesla MRI Neuroimage Clin. 2023; 37:103298. . View in PubMed

Cerebral perfusion and neurological examination characterise neonatal opioid withdrawal syndrome: a prospective cohort study Arch Dis Child Fetal Neonatal Ed. 2022 Jul; 107(4):414-420. . View in PubMed

Corrigendum to "Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla" [NeuroImage volume 245, 2021, 118724] Neuroimage. 2022 Apr 15; 250:118921. . View in PubMed

Selective vulnerability of medial temporal regions to short-term blood pressure variability and cerebral hypoperfusion in older adults Neuroimage Rep. 2022 Mar; 2(1). . View in PubMed

Editorial for "Multi-planar, multi-contrast and multi-time point analysis tool (MOCHA) for intracranial vessel wall characterization" J Magn Reson Imaging. 2022 09; 56(3):956-957. . View in PubMed

Multi-echo balanced SSFP with a sequential phase-encoding order for functional MR imaging at 7T Magn Reson Med. 2022 09; 88(3):1303-1313. . View in PubMed

Cerebrovascular reactivity deficits in cognitively unimpaired older adults: vasodilatory versus vasoconstrictive responses Neurobiol Aging. 2022 05; 113:55-62. . View in PubMed

Massively parallel functional photoacoustic computed tomography of the human brain Nat Biomed Eng. 2022 05; 6(5):584-592. . View in PubMed

k-space weighted image average (KWIA) for ASL-based dynamic MR angiography and perfusion imaging Magn Reson Imaging. 2022 02; 86:94-106. . View in PubMed

Optimization of pseudo-continuous arterial spin labeling at 7T with parallel transmission B1 shimming Magn Reson Med. 2022 01; 87(1):249-262. . View in PubMed

Editorial: Multi-parametric perfusion MRI by arterial spin labeling Front Neurosci. 2022; 16:1132835. . View in PubMed

Editorial: Cerebrovascular imaging-From micro- to macroscopic scales Front Neurosci. 2022; 16:1086022. . View in PubMed

Older adults with perivascular spaces exhibit cerebrovascular reactivity deficits Neuroimage. 2022 12 01; 264:119746. . View in PubMed

MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium Alzheimers Dement (Amst). 2022; 14(1):e12362. . View in PubMed

Cerebral blood flow and cardiovascular risk effects on resting brain regional homogeneity Neuroimage. 2022 11 15; 262:119555. . View in PubMed

Association of Intensive vs Standard Blood Pressure Control With Cerebral Blood Flow: Secondary Analysis of the SPRINT MIND Randomized Clinical Trial JAMA Neurol. 2022 04 01; 79(4):380-389. . View in PubMed

Pathophysiological Mechanisms Underlying Idiopathic Normal Pressure Hydrocephalus: A Review of Recent Insights Front Aging Neurosci. 2022; 14:866313. . View in PubMed

Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits Alzheimers Dement (Amst). 2022; 14(1):e12261. . View in PubMed

Modulation of brain networks during MR-compatible transcranial direct current stimulation Neuroimage. 2022 04 15; 250:118874. . View in PubMed

Effects of Repetitive Peripheral Sensory Stimulation in the Subacute and Chronic Phases After Stroke: Study Protocol for a Pilot Randomized Trial Front Neurol. 2022; 13:779128. . View in PubMed

Noncontrast Pediatric Brain Perfusion: Arterial Spin Labeling and Intravoxel Incoherent Motion Magn Reson Imaging Clin N Am. 2021 Nov; 29(4):493-513. . View in PubMed

High-Resolution Neurovascular Imaging at 7T: Arterial Spin Labeling Perfusion, 4-Dimensional MR Angiography, and Black Blood MR Imaging Magn Reson Imaging Clin N Am. 2021 Feb; 29(1):53-65. . View in PubMed

Alzheimers Dement. 2021 12; 17(12):2020-2029. . View in PubMed

Layer-dependent multiplicative effects of spatial attention on contrast responses in human early visual cortex Prog Neurobiol. 2021 12; 207:101897. . View in PubMed

Assessment of carotid stiffness by measuring carotid pulse wave velocity using a single-slice oblique-sagittal phase-contrast MRI Magn Reson Med. 2021 07; 86(1):442-455. . View in PubMed

Optimization of adiabatic pulses for pulsed arterial spin labeling at 7 tesla: Comparison with pseudo-continuous arterial spin labeling Magn Reson Med. 2021 06; 85(6):3227-3240. . View in PubMed

Semiautomatic cerebrovascular territory mapping based on dynamic ASL MR angiography without vessel-encoded labeling Magn Reson Med. 2021 05; 85(5):2735-2746. . View in PubMed

MarkVCID cerebral small vessel consortium: IINeuroimaging protocols. Alzheimers Dement. 2021 04; 17(4):716-725. . View in PubMed

Cerebral perfusion is associated with blast exposure in military personnel without moderate or severe TBI J Cereb Blood Flow Metab. 2021 04; 41(4):886-900. . View in PubMed

Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study J Cereb Blood Flow Metab. 2021 03; 41(3):670-683. . View in PubMed

Brain arteriolosclerosis Acta Neuropathol. 2021 01; 141(1):1-24. . View in PubMed

Super-Resolution Arterial Spin Labeling Using Slice-Dithered Enhanced Resolution and Simultaneous Multi-Slice Acquisition Front Neurosci. 2021; 15:737525. . View in PubMed

Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease Front Neurosci. 2021; 15:627627. . View in PubMed

Retrospective motion artifact correction of structural MRI images using deep learning improves the quality of cortical surface reconstructions Neuroimage. 2021 04 15; 230:117756. . View in PubMed

In-vivo imaging of targeting and modulation of depression-relevant circuitry by transcranial direct current stimulation: a randomized clinical trial Transl Psychiatry. 2021 02 24; 11(1):138. . View in PubMed

Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla Neuroimage. 2021 12 15; 245:118724. . View in PubMed

Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge Neuroimage. 2021 12 15; 245:118754. . View in PubMed

A novel technique for accurate electrode placement over cortical targets for transcranial electrical stimulation (tES) clinical trials J Neural Eng. 2021 10 11; 18(5). . View in PubMed

Consensus-based technical recommendations for clinical translation of renal ASL MRI MAGMA. 2020 Feb; 33(1):141-161. . View in PubMed

Low Dose CT Perfusion With K-Space Weighted Image Average (KWIA) IEEE Trans Med Imaging. 2020 12; 39(12):3879-3890. . View in PubMed

Dynamics of the cerebral blood flow response to brief neural activity in human visual cortex J Cereb Blood Flow Metab. 2020 09; 40(9):1823-1837. . View in PubMed

Human Placenta Blood Flow During Early Gestation With Pseudocontinuous Arterial Spin Labeling MRI J Magn Reson Imaging. 2020 04; 51(4):1247-1257. . View in PubMed

Single and repeated ketamine treatment induces perfusion changes in sensory and limbic networks in major depressive disorder Eur Neuropsychopharmacol. 2020 04; 33:89-100. . View in PubMed

Deep Learning Detection of Penumbral Tissue on Arterial Spin Labeling in Stroke Stroke. 2020 02; 51(2):489-497. . View in PubMed

Robust functional mapping of layer-selective responses in human lateral geniculate nucleus with high-resolution 7T fMRI Proc Biol Sci. 2020 04 29; 287(1925):20200245. . View in PubMed

Concurrent Imaging of Markers of Current Flow and Neurophysiological Changes During tDCS Front Neurosci. 2020; 14:374. . View in PubMed

Robust single-shot acquisition of high resolution whole brain ASL images by combining time-dependent 2D CAPIRINHA sampling with spatio-temporal TGV reconstruction Neuroimage. 2020 02 01; 206:116337. . View in PubMed

Editorial: Advances in Multi-Scale Analysis of Brain Complexity Front Neurosci. 2020; 14:337. . View in PubMed

Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort Front Neurosci. 2020; 14:571480. . View in PubMed

Reperfusion Into Severely Damaged Brain Tissue Is Associated With Occurrence of Parenchymal Hemorrhage for Acute Ischemic Stroke Front Neurol. 2020; 11:586. . View in PubMed

Lower retinal capillary density in minimal cognitive impairment among older Latinx adults Alzheimers Dement (Amst). 2020; 12(1):e12071. . View in PubMed

A review of transcranial direct current stimulation (tDCS) for the individualized treatment of depressive symptoms Pers Med Psychiatry. 2019 Nov-Dec; 17-18:17-22. . View in PubMed

Br J Radiol. 2019 Feb; 92(1094):20180492. . View in PubMed

Hypercapnia increases brain viscoelasticity J Cereb Blood Flow Metab. 2019 12; 39(12):2445-2455. . View in PubMed

Recent Advances in Pediatric Brain, Spine, and Neuromuscular Magnetic Resonance Imaging Techniques Pediatr Neurol. 2019 07; 96:7-23. . View in PubMed

Quantification of intracranial arterial blood flow using noncontrast enhanced 4D dynamic MR angiography Magn Reson Med. 2019 07; 82(1):449-459. . View in PubMed

Mapping water exchange across the blood-brain barrier using 3D diffusion-prepared arterial spin labeled perfusion MRI Magn Reson Med. 2019 05; 81(5):3065-3079. . View in PubMed

7-Tesla MRI of the brain in a research subject with bilateral, total knee replacement implants: Case report and proposed safety guidelines Magn Reson Imaging. 2019 04; 57:313-316. . View in PubMed

Multidelay multiparametric arterial spin labeling perfusion MRI and mild cognitive impairment in early stage Parkinson's disease Hum Brain Mapp. 2019 03; 40(4):1317-1327. . View in PubMed

Vascular dysfunction-The disregarded partner of Alzheimer's disease Alzheimers Dement. 2019 01; 15(1):158-167. . View in PubMed

Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis J Cereb Blood Flow Metab. 2019 01; 39(1):108-117. . View in PubMed

An Automatic Estimation of Arterial Input Function Based on Multi-Stream 3D CNN Front Neuroinform. 2019; 13:49. . View in PubMed

Characterization of lenticulostriate arteries with high resolution black-blood T1-weighted turbo spin echo with variable flip angles at 3 and 7? Tesla. Neuroimage. 2019 10 01; 199:184-193.. View in PubMed

Multi-phase 3D arterial spin labeling brain MRI in assessing cerebral blood perfusion and arterial transit times in children at 3T Clin Imaging. 2019 Jan - Feb; 53:210-220. . View in PubMed

Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability Sci Rep. 2019 11 26; 9(1):17605. . View in PubMed

Value of pituitary gland MRI at 7 T in Cushing's disease and relationship to inferior petrosal sinus sampling: case report J Neurosurg. 2018 Mar 01; 1-5. . View in PubMed

Noncontrast-enhanced time-resolved 4D dynamic intracranial MR angiography at 7T: A feasibility study J Magn Reson Imaging. 2018 07; 48(1):111-120. . View in PubMed

Measuring human placental blood flow with multidelay 3D GRASE pseudocontinuous arterial spin labeling at 3T J Magn Reson Imaging. 2018 06; 47(6):1667-1676. . View in PubMed

ASPECTS-based reperfusion status on arterial spin labeling is associated with clinical outcome in acute ischemic stroke patients J Cereb Blood Flow Metab. 2018 03; 38(3):382-392. . View in PubMed

Accelerated noncontrast-enhanced 4-dimensional intracranial MR angiography using golden-angle stack-of-stars trajectory and compressed sensing with magnitude subtraction Magn Reson Med. 2018 02; 79(2):867-878. . View in PubMed

A constrained slice-dependent background suppression scheme for simultaneous multislice pseudo-continuous arterial spin labeling Magn Reson Med. 2018 Jan; 79(1):394-400. . View in PubMed

Low-dose CT perfusion with projection view sharing Med Phys. 2018 Jan; 45(1):101-113. . View in PubMed

Regional association of pCASL-MRI with FDG-PET and PiB-PET in people at risk for autosomal dominant Alzheimer's disease Neuroimage Clin. 2018; 17:751-760. . View in PubMed

Neurophysiological Basis of Multi-Scale Entropy of Brain Complexity and Its Relationship With Functional Connectivity Front Neurosci. 2018; 12:352. . View in PubMed

Improved sensitivity of cellular MRI using phase-cycled balanced SSFP of ferumoxytol nanocomplex-labeled macrophages at ultrahigh field Int J Nanomedicine. 2018; 13:3839-3852. . View in PubMed

Correction: Neurophysiological Basis of Multi-Scale Entropy of Brain Complexity and Its Relationship With Functional Connectivity Front Neurosci. 2018; 12:539. . View in PubMed

Default Mode Network Complexity and Cognitive Decline in Mild Alzheimer's Disease Front Neurosci. 2018; 12:770. . View in PubMed

Imbalance of Functional Connectivity and Temporal Entropy in Resting-State Networks in Autism Spectrum Disorder: A Machine Learning Approach Front Neurosci. 2018; 12:869. . View in PubMed

Highly Accelerated SSFP Imaging with Controlled Aliasing in Parallel Imaging and integrated-SSFP (CAIPI-iSSFP) Investig Magn Reson Imaging. 2017 Dec; 21(4):210-222. . View in PubMed

Golden-ratio rotated stack-of-stars acquisition for improved volumetric MRI Magn Reson Med. 2017 Dec; 78(6):2290-2298. . View in PubMed

Application of arterial spin labeling perfusion MRI to differentiate benign from malignant intracranial meningiomas Eur J Radiol. 2017 Dec; 97:31-36. . View in PubMed

Prospective motion correction for 3D GRASE pCASL with volumetric navigators Proc Int Soc Magn Reson Med Sci Meet Exhib Int Soc Magn Reson Med Sci Meet Exhib. 2017 Apr; 25:0680. . View in PubMed

Integrated SSFP for functional brain mapping at 7T with reduced susceptibility artifact J Magn Reson. 2017 Mar; 276:22-30. . View in PubMed

Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke Oncotarget. 2017 Jan 10; 8(2):2437-2443. . View in PubMed

Arterial spin labeling MRI is able to detect early hemodynamic changes in diabetic nephropathy J Magn Reson Imaging. 2017 12; 46(6):1810-1817. . View in PubMed

Reduced regional cerebral blood flow in patients with heart failure Eur J Heart Fail. 2017 10; 19(10):1294-1302. . View in PubMed

Altered Glutamate and Regional Cerebral Blood Flow Levels in Schizophrenia: A 1H-MRS and pCASL study Neuropsychopharmacology. 2017 01; 42(2):562-571. . View in PubMed

Multi-phase passband balanced SSFP fMRI with 50ms sampling rate at 7Tesla enables high precision in resolving 100ms neuronal events Magn Reson Imaging. 2017 Jan; 35:20-28. . View in PubMed

Changes in Cerebral Blood Flow during an Alteration in Glycemic State in a Large Non-human Primate (Papio hamadryas sp). Front Neurosci. 2017; 11:49. . View in PubMed

A longitudinal study of cerebral blood flow under hypoxia at high altitude using 3D pseudo-continuous arterial spin labeling Sci Rep. 2017 02 27; 7:43246. . View in PubMed

Cerebral Hemodynamic and White Matter Changes of Type 2 Diabetes Revealed by Multi-TI Arterial Spin Labeling and Double Inversion Recovery Sequence Front Neurol. 2017; 8:717. . View in PubMed

Quantification of liver perfusion using multidelay pseudocontinuous arterial spin labeling J Magn Reson Imaging. 2016 May; 43(5):1046-54. . View in PubMed

Reduced perfusion in normal-appearing white matter in mild to moderate hypertension as revealed by 3D pseudocontinuous arterial spin labeling J Magn Reson Imaging. 2016 Mar; 43(3):635-43. . View in PubMed

Arterial Spin Labeling Magnetic Resonance Imaging Estimation of Antegrade and Collateral Flow in Unilateral Middle Cerebral Artery Stenosis Stroke. 2016 Feb; 47(2):428-33. . View in PubMed

Phase-cycled simultaneous multislice balanced SSFP imaging with CAIPIRINHA for efficient banding reduction Magn Reson Med. 2016 12; 76(6):1764-1774. . View in PubMed

Comparison of non-invasive MRI measurements of cerebral blood flow in a large multisite cohort J Cereb Blood Flow Metab. 2016 07; 36(7):1244-56. . View in PubMed

How the heart speaks to the brain: neural activity during cardiorespiratory interoceptive stimulation Philos Trans R Soc Lond B Biol Sci. 2016 11 19; 371(1708). . View in PubMed

Patterns of postictal cerebral perfusion in idiopathic generalized epilepsy: a multi-delay multi-parametric arterial spin labelling perfusion MRI study Sci Rep. 2016 07 04; 6:28867. . View in PubMed

In-vivo Imaging of Magnetic Fields Induced by Transcranial Direct Current Stimulation (tDCS) in Human Brain using MRI Sci Rep. 2016 10 04; 6:34385. . View in PubMed

Noise Reduction in Arterial Spin Labeling Based Functional Connectivity Using Nuisance Variables Front Neurosci. 2016; 10:371. . View in PubMed

Developmental trajectories of cerebral blood flow and oxidative metabolism at baseline and during working memory tasks Neuroimage. 2016 07 01; 134:587-596. . View in PubMed

Assessing intracranial vascular compliance using dynamic arterial spin labeling Neuroimage. 2016 Jan 01; 124(Pt A):433-441. . View in PubMed

Astrocytic tumour grading: a comparative study of three-dimensional pseudocontinuous arterial spin labelling, dynamic susceptibility contrast-enhanced perfusion-weighted imaging, and diffusion-weighted imaging Eur Radiol. 2015 Dec; 25(12):3423-30. . View in PubMed

Detection of Hyperperfusion on Arterial Spin Labeling using Deep Learning Proceedings (IEEE Int Conf Bioinformatics Biomed). 2015 Nov; 2015:1322-1327. . View in PubMed

Characterizing Resting-State Brain Function Using Arterial Spin Labeling Brain Connect. 2015 Nov; 5(9):527-42. . View in PubMed

Towards the identification of multi-parametric quantitative MRI biomarkers in lupus nephritis Magn Reson Imaging. 2015 Nov; 33(9):1066-1074. . View in PubMed

Water Exchange across the Blood-Brain Barrier in Obstructive Sleep Apnea: An MRI Diffusion-Weighted Pseudo-Continuous Arterial Spin Labeling Study J Neuroimaging. 2015 Nov-Dec; 25(6):900-5. . View in PubMed

Reliability comparison of spontaneous brain activities between BOLD and CBF contrasts in eyes-open and eyes-closed resting states Neuroimage. 2015 Nov 01; 121:91-105. . View in PubMed

Perfusion shift from white to gray matter may account for processing speed deficits in schizophrenia Hum Brain Mapp. 2015 Oct; 36(10):3793-804. . View in PubMed

Wavelet-based regularity analysis reveals recurrent spatiotemporal behavior in resting-state fMRI Hum Brain Mapp. 2015 Sep; 36(9):3603-20. . View in PubMed

Altered resting perfusion and functional connectivity of default mode network in youth with autism spectrum disorder Brain Behav. 2015 Sep; 5(9):e00358. . View in PubMed

Simultaneous multi-slice Turbo-FLASH imaging with CAIPIRINHA for whole brain distortion-free pseudo-continuous arterial spin labeling at 3 and 7 T Neuroimage. 2015 Jun; 113:279-88. . View in PubMed

Multi-vendor reliability of arterial spin labeling perfusion MRI using a near-identical sequence: implications for multi-center studies Neuroimage. 2015 Jun; 113:143-52. . View in PubMed

Associations of resting-state fMRI functional connectivity with flow-BOLD coupling and regional vasculature Brain Connect. 2015 Apr; 5(3):137-46. . View in PubMed

Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):630-7. . View in PubMed

Functional connectivity in BOLD and CBF data: similarity and reliability of resting brain networks Neuroimage. 2015 Feb 01; 106:111-22. . View in PubMed

Eigenanatomy: sparse dimensionality reduction for multi-modal medical image analysis Methods. 2015 Feb; 73:43-53. . View in PubMed

Decomposing cerebral blood flow MRI into functional and structural components: a non-local approach based on prediction Neuroimage. 2015 Jan 15; 105:156-70. . View in PubMed

Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia Magn Reson Med. 2015 Jan; 73(1):102-16. . View in PubMed

Detecting static and dynamic differences between eyes-closed and eyes-open resting states using ASL and BOLD fMRI PLoS One. 2015; 10(3):e0121757. . View in PubMed

Impaired Cerebrovascular Function in Coronary Artery Disease Patients and Recovery Following Cardiac Rehabilitation Front Aging Neurosci. 2015; 7:224. . View in PubMed

The pediatric template of brain perfusion Sci Data. 2015; 2:150003. . View in PubMed

Noncontrast enhanced four-dimensional dynamic MRA with golden angle radial acquisition and K-space weighted image contrast (KWIC) reconstruction Magn Reson Med. 2014 Dec; 72(6):1541-51. . View in PubMed

Simultaneous fMRI-PET of the opioidergic pain system in human brain Neuroimage. 2014 Nov 15; 102 Pt 2:275-82. . View in PubMed

Effect of high dose isoflurane on cerebral blood flow in macaque monkeys Magn Reson Imaging. 2014 Sep; 32(7):956-60. . View in PubMed

Transcranial electrical stimulation modifies the neuronal response to psychosocial stress exposure Hum Brain Mapp. 2014 Aug; 35(8):3750-9. . View in PubMed

Metric optimization for surface analysis in the Laplace-Beltrami embedding space IEEE Trans Med Imaging. 2014 Jul; 33(7):1447-63. . View in PubMed

Multiple time scale complexity analysis of resting state FMRI Brain Imaging Behav. 2014 Jun; 8(2):284-91. . View in PubMed

Multi-delay arterial spin labeling perfusion MRI in moyamoya disease--comparison with CT perfusion imaging Eur Radiol. 2014 May; 24(5):1135-44. . View in PubMed

Fast local trust region technique for diffusion tensor registration using exact reorientation and regularization IEEE Trans Med Imaging. 2014 May; 33(5):1005-22. . View in PubMed

Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography J Magn Reson Imaging. 2014 Apr; 39(4):931-9. . View in PubMed

Anterior cingulate GABA levels predict whole-brain cerebral blood flow Neurosci Lett. 2014 Feb 21; 561:188-91. . View in PubMed

Time-resolved noncontrast enhanced 4-D dynamic magnetic resonance angiography using multibolus TrueFISP-based spin tagging with alternating radiofrequency (TrueSTAR) Magn Reson Med. 2014 Feb; 71(2):551-60. . View in PubMed

Interhemispheric cerebral blood flow balance during recovery of motor hand function after ischemic stroke--a longitudinal MRI study using arterial spin labeling perfusion PLoS One. 2014; 9(9):e106327. . View in PubMed

Single-subject structural networks with closed-form rotation invariant matching mprove power in developmental studies of the cortex Med Image Comput Comput Assist Interv. 2014; 17(Pt 3):137-44. . View in PubMed

Detecting resting-state brain activity by spontaneous cerebral blood volume fluctuations using whole brain vascular space occupancy imaging Neuroimage. 2014 Jan 01; 84:575-84. . View in PubMed

Dynamic and static contributions of the cerebrovasculature to the resting-state BOLD signal Neuroimage. 2014 Jan 01; 84:672-80. . View in PubMed

Regional correlation between resting state FDG PET and pCASL perfusion MRI J Cereb Blood Flow Metab. 2013 Dec; 33(12):1909-14. . View in PubMed

Regional cerebral blood flow alterations in obstructive sleep apnea Neurosci Lett. 2013 Oct 25; 555:159-64. . View in PubMed

Quantification of network perfusion in ASL cerebral blood flow data with seed based and ICA approaches Brain Topogr. 2013 Oct; 26(4):569-80. . View in PubMed

Quantitative mouse renal perfusion using arterial spin labeling NMR Biomed. 2013 Oct; 26(10):1225-32. . View in PubMed

Quantitative characterization of nuclear overhauser enhancement and amide proton transfer effects in the human brain at 7 tesla Magn Reson Med. 2013 Oct; 70(4):1070-81. . View in PubMed

Balanced steady state free precession for arterial spin labeling MRI: Initial experience for blood flow mapping in human brain, retina, and kidney Magn Reson Imaging. 2013 Sep; 31(7):1044-50. . View in PubMed

Complexity and synchronicity of resting state blood oxygenation level-dependent (BOLD) functional MRI in normal aging and cognitive decline J Magn Reson Imaging. 2013 Jul; 38(1):36-45. . View in PubMed

Periprocedural arterial spin labeling and dynamic susceptibility contrast perfusion in detection of cerebral blood flow in patients with acute ischemic syndrome Stroke. 2013 Mar; 44(3):664-70. . View in PubMed

Cortical responses to amphetamine exposure studied by pCASL MRI and pharmacokinetic/pharmacodynamic dose modeling Neuroimage. 2013 Mar; 68:75-82. . View in PubMed

Multi-delay multi-parametric arterial spin-labeled perfusion MRI in acute ischemic stroke - Comparison with dynamic susceptibility contrast enhanced perfusion imaging Neuroimage Clin. 2013; 3:1-7. . View in PubMed

Turbo-FLASH based arterial spin labeled perfusion MRI at 7 T PLoS One. 2013; 8(6):e66612. . View in PubMed

Voxelwise spectral diffusional connectivity and its applications to Alzheimer's disease and intelligence prediction Med Image Comput Comput Assist Interv. 2013; 16(Pt 1):655-62. . View in PubMed

Measurement of cerebral white matter perfusion using pseudocontinuous arterial spin labeling 3T magnetic resonance imaging--an experimental and theoretical investigation of feasibility PLoS One. 2013; 8(12):e82679. . View in PubMed

Comparison of pulsed and pseudocontinuous arterial spin-labeling for measuring CO2 -induced cerebrovascular reactivity J Magn Reson Imaging. 2012 Aug; 36(2):312-21. . View in PubMed

Quantification of arterial cerebral blood volume using multiphase-balanced SSFP-based ASL Magn Reson Med. 2012 Jul; 68(1):130-9. . View in PubMed

Noncontrast dynamic MRA in intracranial arteriovenous malformation (AVM), comparison with time of flight (TOF) and digital subtraction angiography (DSA) Magn Reson Imaging. 2012 Jul; 30(6):869-77. . View in PubMed

A two-stage approach for measuring vascular water exchange and arterial transit time by diffusion-weighted perfusion MRI Magn Reson Med. 2012 May; 67(5):1275-84. . View in PubMed

Applications of arterial spin labeled MRI in the brain J Magn Reson Imaging. 2012 May; 35(5):1026-37. . View in PubMed

Longitudinal reproducibility and accuracy of pseudo-continuous arterial spin-labeled perfusion MR imaging in typically developing children Radiology. 2012 May; 263(2):527-36. . View in PubMed

Comparison of arterial transit times estimated using arterial spin labeling MAGMA. 2012 Apr; 25(2):135-44. . View in PubMed

The value of arterial spin-labeled perfusion imaging in acute ischemic stroke: comparison with dynamic susceptibility contrast-enhanced MRI Stroke. 2012 Apr; 43(4):1018-24. . View in PubMed

Fast diffusion tensor registration with exact reorientation and regularization Med Image Comput Comput Assist Interv. 2012; 15(Pt 2):138-45. . View in PubMed

Serotonin transporter genotype modulates the association between depressive symptoms and amygdala activity among psychiatrically healthy adults Psychiatry Res. 2011 Sep 30; 193(3):161-7. . View in PubMed

Potentials and challenges for arterial spin labeling in pharmacological magnetic resonance imaging J Pharmacol Exp Ther. 2011 May; 337(2):359-66. . View in PubMed

Quantification of Load Dependent Brain Activity in Parametric N-Back Working Memory Tasks using Pseudo-continuous Arterial Spin Labeling (pCASL) Perfusion Imaging J Cogn Sci (Seoul). 2011 Apr; 12(2):127-210. . View in PubMed

Test-retest reliability of arterial spin labeling with common labeling strategies J Magn Reson Imaging. 2011 Apr; 33(4):940-9. . View in PubMed

Baseline CBF, and BOLD, CBF, and CMRO2 fMRI of visual and vibrotactile stimulations in baboons J Cereb Blood Flow Metab. 2011 Feb; 31(2):715-24. . View in PubMed

Cerebral blood flow changes associated with different meditation practices and perceived depth of meditation Psychiatry Res. 2011 Jan 30; 191(1):60-7. . View in PubMed

Loss of Coherence of Low Frequency Fluctuations of BOLD FMRI in Visual Cortex of Healthy Aged Subjects Open Neuroimag J. 2011; 5:105-11. . View in PubMed

Relationships between Cerebral Blood Flow and IQ in Typically Developing Children and Adolescents J Cogn Sci (Seoul). 2011; 12(2):151-170. . View in PubMed

Estimation of perfusion and arterial transit time in myocardium using free-breathing myocardial arterial spin labeling with navigator-echo Magn Reson Med. 2010 Nov; 64(5):1289-95. . View in PubMed

In vivo venous blood T1 measurement using inversion recovery true-FISP in children and adults Magn Reson Med. 2010 Oct; 64(4):1140-7. . View in PubMed

Unenhanced dynamic MR angiography: high spatial and temporal resolution by using true FISP-based spin tagging with alternating radiofrequency Radiology. 2010 Jul; 256(1):270-9. . View in PubMed

Quantification issues in arterial spin labeling perfusion magnetic resonance imaging Top Magn Reson Imaging. 2010 Apr; 21(2):65-73. . View in PubMed

I am a Professor of Neurology and Radiology, Director of Imaging Technology Innovation in the Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California. I am also directing the Laboratory of Functional MRI Technology (LOFT)( During the past 20+ years, my research has been focused on the technical development and clinical translations of novel functional and physiological Magnetic Resonance Imaging (MRI) technologies, in particular noninvasive blood flow/perfusion imaging. I am a recognized expert in perfusion and functional MRI with extensive experience in clinical applications related to neurologic and psychiatric disorders as well as body organs. I have also been supporting the scientific community by disseminating arterial spin labeling (ASL) sequences to approximately 300 Siemens imaging research centers around the world. In addition to MRI, I have experience in the technical development and clinical applications of Computed Tomography (CT) and Positron Emission Tomography (PET).
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