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Danny O El-Nachef

Assistant Professor of Research Stem Cell Biology and Regenerative Medicine

Director of Imaging and Genomics

Director of Cores, Department of Stem Cell Biology and Regenerative Medicine

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Email [email protected]
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Publications

  • Early awakenings: new insights into graft-host coupling in cardiac cell therapy. Cardiovasc Res. 2025 Sep 29; 121(11):1638-1639.. View in PubMed
  • Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. Cell Stem Cell. 2025 Oct 02; 32(10):1614-1633.e13.. View in PubMed
  • Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways. PLoS One. 2023; 18(2):e0281610.. View in PubMed
  • Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes. Stem Cell Reports. 2021 10 12; 16(10):2473-2487.. View in PubMed
  • Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo. Circulation. 2021 04 20; 143(16):1635-1638.. View in PubMed
  • High-resolution 3D fluorescent imaging of intact tissues. Int J Cardiol Cardiovasc Dis. 2021; 1(1):1-14.. View in PubMed
  • A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and Their Differentiated Derivatives. Stem Cell Reports. 2020 07 14; 15(1):226-241.. View in PubMed
  • Engineering Heart Morphogenesis. Trends Biotechnol. 2020 08; 38(8):835-845.. View in PubMed
  • O-GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O-GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload. J Am Heart Assoc. 2019 06 04; 8(11):e011260.. View in PubMed
  • Repressive histone methylation regulates cardiac myocyte cell cycle exit. J Mol Cell Cardiol. 2018 08; 121:1-12.. View in PubMed
  • Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth. Epigenetics Chromatin. 2018 04 17; 11(1):18.. View in PubMed
  • Epigenetic regulation of cardiac myocyte differentiation. Front Genet. 2014; 5:375.. View in PubMed
  • Regeneration potential of adult cardiac myocytes. Cell Res. 2013 Aug; 23(8):978-9.. View in PubMed
  • doublesex/mab3 related-1 (dmrt1) is essential for development of anterior neural plate derivatives in Ciona. Development. 2010 Jul; 137(13):2197-203.. View in PubMed
  • The ascidian mouth opening is derived from the anterior neuropore: reassessing the mouth/neural tube relationship in chordate evolution. Dev Biol. 2010 Aug 01; 344(1):138-49.. View in PubMed

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