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Darcy Spicer, MD

Professor of Clinical Medicine

Chief, Division of Oncology, Department of Medicine

Co-Director, Lynne Cohen Clinic

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Phone +1 323 865 3904
Email [email protected]
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Overview

Dr. Spicer has been on faculty at the Keck School of Medicine at USC since 1980 when he began as a Clinical Instructor of Medicine in the Department of Oncology. Dr. Spicer holds several United States patents for his medical inventions. He is a medical oncology attending physician at both the LAC+USC Medical Center and the USC Norris Comprehensive Cancer Center.

Research Funding

  • SCCISARS 2: An e-Solution to Protect Human Subjects
    NIH · S07RR018274 · Sep 1, 2002 – Aug 31, 2006 · Role: Principal Investigator
  • GNRH AGONIST REGIMEN FOR BREAST CANCER PREVENTION
    NIH · U01CA079428 · Sep 15, 1998 – Aug 31, 2000 · Role: Principal Investigator

Media

Publications

  • Breast cancer screening adherence after multigene panel testing among women with pathogenic variants in moderate-risk genes or with empirically increased breast cancer risk. Breast Cancer Res Treat. 2026 Jul 10; 218(1).. View in PubMed
  • Risk-reducing gynecologic surgery decisions in Lynch syndrome at a safety-net hospital and university medical center. Gynecol Oncol. 2026 06; 209:56-61.. View in PubMed
  • MammaTrace – a cell-free DNA methylation plasma only assay for minimal residual disease detection in breast cancer patients. medRxiv. 2025 May 21.. View in PubMed
  • Association of Androgen Receptor Expression With Tumor Immune Landscape and Treatment Outcomes of Patients With Breast Cancer. JCO Precis Oncol. 2025 Apr; 9:e2400459.. View in PubMed
  • Evaluation of markers of immunity in different metastatic immune microenvironments suggests more suppression within breast to liver metastases in breast cancer. Breast Cancer Res Treat. 2024 Jul; 206(2):245-259.. View in PubMed
  • Experiences of a Multiethnic Cohort of Patients Enrolled in a Financial Reimbursement Program for Cancer Clinical Trials. JCO Oncol Pract. 2023 05; 19(5):e801-e810.. View in PubMed
  • Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions. Oncogene. 2023 02; 42(9):627-637.. View in PubMed
  • Effect of Chemotherapy on the Gut Microbiome of Breast Cancer Patients During the First Year of Treatment. Breast Cancer (Dove Med Press). 2022; 14:433-451.. View in PubMed
  • Integration of Universal Germline Genetic Testing for All New Breast Cancer Patients. Ann Surg Oncol. 2023 Feb; 30(2):1017-1025.. View in PubMed
  • Implementation of a Multisite Financial Reimbursement Program in Cancer Clinical Trials Integrated With Patient Navigation: A Pilot Randomized Clinical Trial. JCO Oncol Pract. 2022 06; 18(6):e915-e924.. View in PubMed

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