Keck School Faculty

Darcy Spicer, MD
Darcy Spicer, MD
Associate Professor of Clinical Medicine;Assistant Dean for Clinical Research Studies;Chief, Division of Oncology, Department of Medicine/Cancer Center;IRB Director & Co-Director, Lynne Cohen Clinic
NOR 3446 Health Sciences Campus Los Angeles
Dr. Spicer has been on faculty at the Keck School of Medicine at USC since 1980 when he began as a Clinical Instructor of Medicine in the Department of Oncology. Currently an associate professor, Dr. Spicer is also the Co-Director of the Clinical Investigations Support Office at USC Norris Comprehensive Cancer and Hospital. Dr. Spicer holds several United States patents for his medical inventions and chairs Keck’s Institutional Review Board, overseeing that faculty research is conducted ethically. He is a medical oncology attending physician at both the LAC+USC Medical Center and the USC Norris Comprehensive Cancer Center, a General Medicine Ward Attending Physician at LAC+USC Medical Center and is the founder of Balance Pharmaceuticals based in Los Angeles.

Hispanic ethnicity as a moderator of the effects of aerobic and resistance exercise in survivors of breast cancer Cancer. 2019 Mar 15; 125(6):910-920. . View in PubMed

Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial Breast Cancer Res. 2018 Oct 19; 20(1):124. . View in PubMed

Reply to EParkin et al. J Clin Oncol. 2018 Jul 10; 36(20):2129-2130. . View in PubMed

Overcoming endocrine resistance in metastatic hormone receptor-positive breast cancer J Hematol Oncol. 2018 Jun 11; 11(1):80. . View in PubMed

Reply to EParkin et al. J Clin Oncol. 2018 May 30; JCO2018787754. . View in PubMed

Effects of Aerobic and Resistance Exercise on Metabolic Syndrome, Sarcopenic Obesity, and Circulating Biomarkers in Overweight or Obese Survivors of Breast Cancer: A Randomized Controlled Trial J Clin Oncol. 2018 Mar 20; 36(9):875-883. . View in PubMed

Adipose tissue inflammation in breast cancer survivors: effects of a 16-week combined aerobic and resistance exercise training intervention Breast Cancer Res Treat. 2018 Feb; 168(1):147-157. . View in PubMed

Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density Cancer Prev Res (Phila). 2015 Oct; 8(10):942-51. . View in PubMed

Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone Biomed Res Int. 2015; 2015:934164. . View in PubMed

Biological effects of green tea capsule supplementation in pre-surgery postmenopausal breast cancer patients Front Oncol. 2013; 3:298. . View in PubMed

Lowering oral contraceptive norethindrone dose increases estrogen and progesterone receptor levels with no reduction in proliferation of breast epithelium: a randomized trial Contraception. 2012 Sep; 86(3):238-43. . View in PubMed

Soy isoflavones for breast cancer risk reduction Cancer Prev Res (Phila). 2012 Jul; 5(7):984-5; author reply 986-7. . View in PubMed

Breast epithelial cell proliferation is markedly increased with short-term high levels of endogenous estrogen secondary to controlled ovarian hyperstimulation Breast Cancer Res Treat. 2012 Apr; 132(2):653-60. . View in PubMed

Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women Cancer Prev Res (Phila). 2012 Mar; 5(3):393-402. . View in PubMed

Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young women J Clin Oncol. 2011 Nov 20; 29(33):4373-80. . View in PubMed

GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy Int J Cancer. 2011 Feb 01; 128(3):726-31. . View in PubMed

Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival Breast Cancer Res Treat. 2010 Dec; 124(3):723-32. . View in PubMed

Progesterone and estrogen receptors in pregnant and premenopausal non-pregnant normal human breast Breast Cancer Res Treat. 2009 Nov; 118(1):161-8. . View in PubMed

Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer J Clin Oncol. 2009 May 01; 27(13):2163-9. . View in PubMed

Tamoxifen, soy, and lifestyle factors in Asian American women with breast cancer J Clin Oncol. 2007 Jul 20; 25(21):3024-30. . View in PubMed

Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriers Clin Cancer Res. 2007 Jan 15; 13(2 Pt 1):654-8. . View in PubMed

GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer Cancer Res. 2006 Aug 15; 66(16):7849-53. . View in PubMed

Effect of valspodar on the pharmacokinetics of unbound paclitaxel Invest New Drugs. 2003 Aug; 21(3):291-8. . View in PubMed

Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial J Clin Oncol. 2003 Mar 01; 21(5):864-70. . View in PubMed

Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer Int J Radiat Oncol Biol Phys. 2002 Feb 01; 52(2):397-405. . View in PubMed

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