David R. Freyer, DO

Dr. David Freyer joined Children’s Hospital Los Angeles in January 2008. As Director of the LIFE Program, he oversees all aspects of its services, which include clinical assessments of more than 350 patients annually, research regarding their long-term outcomes, and training of fellows, residents, and other health care professionals in the care of childhood cancer survivors. His clinical and research activities have focused principally on cancer survivorship and cancer control, including the recognition, management and prevention of short-and long-term morbidity of treatment, as well as health care transition for young adult survivors of childhood cancer, adolescent and young adult (AYA) oncology, palliative care, and decision-making at the end of life. Dr. Freyer is a member of the Children’s Oncology Group where he serves as chair of the AYA Committee, on the Steering Committees for the Survivorship & Outcomes and Cancer Control Committees, and on several protocol and administrative committees. Dr. Freyer graduated magna cum laude from DePauw University, obtained his medical degree from the Des Moines University College of Osteopathic Medicine and Surgery, and completed post-graduate medical training at Chicago College of Osteopathic Medicine and Hospitals, Rush University Medical Center and the University of Michigan Medical Center. In 2007, he obtained a MS degree in Clinical Research Design and Statistical Analysis from the University of Michigan School of Public Health.

• Prevalence of Adverse Event Reporting in Adolescents and Young Adults Enrolled in Cancer Clinical Trials JCO Oncol Pract. 2023 Nov; 19(11):1048-1052. . View in PubMed
• Unmet Needs, Barriers, and Facilitators for Conducting Adolescent and Young Adult Cancer Survivorship Research in Southern California: A Delphi Survey J Adolesc Young Adult Oncol. 2023 Oct; 12(5):765-772. . View in PubMed
• Sexual dysfunction among early-onset colorectal cancer survivors: Sex-specific correlates of sexual health discussions between patients and providers Cancer Causes Control. 2023 Aug 19. . View in PubMed
• Gaps in Adolescent and Young Adult Cancer Education in Oncology Fellowship Training J Adolesc Young Adult Oncol. 2023 Jul 21. . View in PubMed
• Reevaluation of sodium thiosulfate otoprotection using the consensus International Society of Paediatric Oncology Ototoxicity Scale: A report from the Children’s Oncology Group study ACCL0431 Pediatr Blood Cancer. 2023 Jul 07; e30550. . View in PubMed
• The Electronic Surviving Cancer Competently Intervention Program-a Psychosocial Digital Health Intervention for English- and Spanish-Speaking Parents of Children With Cancer: Protocol for Randomized Controlled Trial JMIR Res Protoc. 2023 Jun 02; 12:e46339. . View in PubMed
• Clinical Trial Participation: A Qualitative Study of Adolescents and Younger Adults Recently Diagnosed with Cancer J Adolesc Young Adult Oncol. 2023 Jun; 12(3):303-313. . View in PubMed
• Left Ventricle Size Correlates with Peak Exercise Capacity in Pediatric Cancer Survivors Exposed to Anthracycline Chemotherapy Pediatr Cardiol. 2023 May 22. . View in PubMed
• Symptom management care pathway adaptation process and specific adaptation decisions BMC Cancer. 2023 Apr 17; 23(1):350. . View in PubMed
• Patient Care Satisfaction and Emergency Room Utilization among Young Adult Colorectal Cancer Survivors during the SARS-CoV-2 Pandemic: Lessons Learned J Clin Med. 2023 Jan 06; 12(2). . View in PubMed
• Children’s Oncology Group 2023 blueprint for research: Adolescent and young adult oncology Pediatr Blood Cancer. 2023 09; 70 Suppl 6:e30564. . View in PubMed
• Current pediatric cancer survivorship practices: a report from the Children’s Oncology Group J Cancer Surviv. 2023 08; 17(4):1139-1148. . View in PubMed
• Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population Br J Haematol. 2023 07; 202(1):e3-e6. . View in PubMed
• Psychosocial impact of COVID-19 on caregivers and adolescents and young adult survivors of childhood cancer Pediatr Blood Cancer. 2023 06; 70(6):e30291. . View in PubMed
• Prevalence and correlates of skin examination among ethnically diverse young adult survivors of childhood cancer Cancer Med. 2023 04; 12(7):8557-8566. . View in PubMed
• Fertility Preservation Practices at Pediatric Oncology Institutions in the United States: A Report From the Children’s Oncology Group JCO Oncol Pract. 2023 04; 19(4):e550-e558. . View in PubMed
• Transition practices for survivors of childhood cancer: a report from the Children’s Oncology Group J Cancer Surviv. 2023 04; 17(2):342-350. . View in PubMed
• Substance Use Among Young Adult Survivors of Childhood Cancer With Cognitive Impairment: An Analysis of the Project Forward Cohort JCO Oncol Pract. 2023 03; 19(3):e345-e354. . View in PubMed
• Special considerations in the design and implementation of pediatric otoprotection trials J Cancer Surviv. 2023 02; 17(1):4-16. . View in PubMed
• Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial Clin Cancer Res. 2023 07 05; 29(13):2410-2418. . View in PubMed
• Impact of Volumetric Dosimetry on the Projected Cost of Radiation-Related Late Effects Screening After Childhood Cancer: A Real-World Cohort Analysis Oncologist. 2023 09 07; 28(9):e784-e792. . View in PubMed
• Risk of early death in adolescents and young adults with cancer: a population-based study J Natl Cancer Inst. 2023 04 11; 115(4):447-455. . View in PubMed
• Dexrazoxane and Long-Term Heart Function in Survivors of Childhood Cancer J Clin Oncol. 2023 04 20; 41(12):2248-2257. . View in PubMed
• Loss to follow-up of minorities, adolescents, and young adults on clinical trials: A report from the Children’s Oncology Group Cancer. 2023 05 15; 129(10):1547-1556. . View in PubMed
• Capturing the young child’s reports of cancer treatment tolerability: Does our practice reflect an assumption that they cannot report? Pediatr Blood Cancer. 2023 Jan; 70(1):e30028.. View in PubMed
• The integration of primary care and childhood cancer survivorship care: a scoping review J Cancer Surviv. 2022 Dec 19. . View in PubMed
• Risk of Presenting with Poor-Prognosis Metastatic Cancer in Adolescents and Young Adults: A Population-Based Study Cancers (Basel). 2022 Oct 08; 14(19). . View in PubMed
• Cardiometabolic Risk in Childhood Cancer Survivors: A Report from the Children’s Oncology Group Cancer Epidemiol Biomarkers Prev. 2022 Mar 01; 31(3):536-542. . View in PubMed
• Southern California Pediatric and Adolescent Cancer Survivorship (SC-PACS): Establishing a Multi-Institutional Childhood, Adolescent, and Young Adult Cancer Survivorship Consortium in Southern California Cureus. 2022 Feb; 14(2):e21981. . View in PubMed
• Longitudinal use of patient reported outcomes in pediatric leukemia and lymphoma reveals clinically relevant symptomatic adverse events Pediatr Blood Cancer. 2022 12; 69(12):e29986. . View in PubMed
• Palliative care among adult cancer survivors: Knowledge, attitudes, and correlates Palliat Support Care. 2022 06; 20(3):342-347. . View in PubMed
• Sodium thiosulfate for prevention of cisplatin-induced hearing loss: updated survival from ACCL0431 Lancet Oncol. 2022 05; 23(5):570-572. . View in PubMed
• Impacts of the SARS-CoV-2 Pandemic on Young Adult Colorectal Cancer Survivors J Adolesc Young Adult Oncol. 2022 04; 11(2):229-233. . View in PubMed
• Use of Communication Technology to Improve Clinical Trial Participation in Adolescents and Young Adults With Cancer: Consensus Statement From the Children’s Oncology Group Adolescent and Young Adult Responsible Investigator Network JCO Oncol Pract. 2022 03; 18(3):224-231. . View in PubMed
• Adolescent and young adult (AYA) versus pediatric patients with acute leukemia have a significantly increased risk of acute GVHD following unrelated donor (URD) stem cell transplantation (SCT): the Children’s Oncology Group experience Bone Marrow Transplant. 2022 03; 57(3):445-452. . View in PubMed
• Infrastructure of Fertility Preservation Services for Pediatric Cancer Patients: A Report From the Children’s Oncology Group JCO Oncol Pract. 2022 03; 18(3):e325-e333. . View in PubMed
• Insurance coverage change and survivorship care among young adult survivors of childhood cancer Health Serv Res. 2022 02; 57(1):159-171. . View in PubMed
• Lack of Concordance in Symptomatic Adverse Event Reporting by Children, Clinicians, and Caregivers: Implications for Cancer Clinical Trials J Clin Oncol. 2022 05 20; 40(15):1623-1634. . View in PubMed
• DNMT3A overgrowth syndrome is associated with the development of hematopoietic malignancies in children and young adults Blood. 2022 01 20; 139(3):461-464. . View in PubMed
• Shared barriers and facilitators to enrollment of adolescents and young adults on cancer clinical trials Sci Rep. 2022 03 09; 12(1):3875. . View in PubMed
• Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates Oncologist. 2022 07 05; 27(7):579-586. . View in PubMed
• Comparing Barriers and Facilitators to Adolescent and Young Adult Clinical Trial Enrollment Across High- and Low-Enrolling Community-Based Clinics Oncologist. 2022 05 06; 27(5):363-370. . View in PubMed
• Survival of Adolescents and Young Adults with Prevalent Poor-Prognosis Metastatic Cancers: A Population-Based Study of Contemporary Patterns and Their Implications Cancer Epidemiol Biomarkers Prev. 2022 04 01; 31(4):900-908. . View in PubMed
• Social networks of oncology clinicians as a means for increasing survivorship clinic referral Commun Med (Lond). 2022; 2:89. . View in PubMed
• Late health outcomes after dexrazoxane treatment: A report from the Children’s Oncology Group Cancer. 2022 02 15; 128(4):788-796. . View in PubMed
• Integrating primary care and childhood cancer survivorship care: a scoping review protocol BMJ Open. 2022 05 16; 12(5):e059050. . View in PubMed
• Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report JAMA Oncol. 2021 Oct 01; 7(10):1550-1558. . View in PubMed
• Time from Diagnosis and Correlates of Health-Related Quality of Life among Young Adult Colorectal Cancer Survivors Cancers (Basel). 2021 Aug 11; 13(16). . View in PubMed
• A Population-Based Analysis of 30-Year Mortality among Five-Year Survivors of Adolescent and Young Adult Cancer: The Roles of Primary Cancer, Subsequent Malignancy, and Other Health Conditions Cancers (Basel). 2021 Aug 05; 13(16). . View in PubMed
• A Case Series of Multiple Primary Malignancies Among Patients With Advanced Melanoma Cureus. 2021 Jun; 13(6):e15480. . View in PubMed
• Patterns of Cancer Care and Association with Survival among Younger Adolescents and Young Adults: A Population-Based Retrospective Cohort Study Cancer Epidemiol Biomarkers Prev. 2021 11; 30(11):2105-2113. . View in PubMed
• Project Forward: A Population-Based Cohort Among Young Adult Survivors of Childhood Cancers JNCI Cancer Spectr. 2021 10; 5(5). . View in PubMed
• Identifying metrics of success for transitional care practices in childhood cancer survivorship: A qualitative interview study of parents Cancer Med. 2021 09; 10(18):6239-6248. . View in PubMed
• Association of language proficiency, sociodemographics, and neurocognitive functioning in dual-language Latino survivors of childhood acute lymphoblastic leukemia and lymphoma Pediatr Blood Cancer. 2021 09; 68(9):e29118. . View in PubMed
• Pediatric oncology clinician communication about sexual health with adolescents and young adults: A report from the children’s oncology group Cancer Med. 2021 08; 10(15):5110-5119. . View in PubMed
• Poor-Prognosis Metastatic Cancers in Adolescents and Young Adults: Incidence Patterns, Trends, and Disparities JNCI Cancer Spectr. 2021 06; 5(3). . View in PubMed
• Barriers and Facilitators to Adolescent and Young Adult Cancer Trial Enrollment: NCORP Site Perspectives JNCI Cancer Spectr. 2021 06; 5(3). . View in PubMed
• Sexual health among adolescent and young adult cancer survivors: A scoping review from the Children’s Oncology Group Adolescent and Young Adult Oncology Discipline Committee CA Cancer J Clin. 2021 05; 71(3):250-263. . View in PubMed
• Surveillance for radiation-related late effects in childhood cancer survivors: The impact of using volumetric dosimetry Cancer Med. 2021 02; 10(3):905-913. . View in PubMed
• Patients, caregivers, and clinicians differ in performance status ratings: Implications for pediatric cancer clinical trials Cancer. 2021 10 01; 127(19):3664-3670. . View in PubMed
• Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial Blood Adv. 2021 04 13; 5(7):1853-1861. . View in PubMed
• Validation of the caregiver Pediatric Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events measure Cancer. 2021 05 01; 127(9):1483-1494. . View in PubMed
• Estimating cancer treatment intensity from SEER cancer registry data: methods and implications for population-based registry studies of pediatric cancers Cancer Causes Control. 2020 Oct; 31(10):881-890. . View in PubMed
• Identifying metrics of success for transitional care practices in childhood cancer survivorship: a qualitative interview study of survivors BMC Cancer. 2020 Sep 21; 20(1):898. . View in PubMed
• Profiles of emotional distress and growth among adolescents and young adults with cancer: A longitudinal study Health Psychol. 2020 May; 39(5):370-380. . View in PubMed
• Assessment of provider perspectives on otoprotection research for children and adolescents: A Children’s Oncology Group Cancer Control and Supportive Care Committee survey Pediatr Blood Cancer. 2020 11; 67(11):e28647. . View in PubMed
• The Children’s Oncology Group Adolescent and Young Adult Responsible Investigator Network: A New Model for Addressing Site-Level Factors Impacting Clinical Trial Enrollment J Adolesc Young Adult Oncol. 2020 08; 9(4):522-527. . View in PubMed
• Enrollment of adolescents and young adults onto SWOG cancer research network clinical trials: A comparative analysis by treatment site and era Cancer Med. 2020 03; 9(6):2146-2152. . View in PubMed
• Late mortality and chronic health conditions in long-term survivors of early-adolescent and young adult cancers: a retrospective cohort analysis from the Childhood Cancer Survivor Study Lancet Oncol. 2020 03; 21(3):421-435. . View in PubMed
• Prevention of cisplatin-induced ototoxicity in children and adolescents with cancer: a clinical practice guideline Lancet Child Adolesc Health. 2020 02; 4(2):141-150. . View in PubMed
• Mapping child and adolescent self-reported symptom data to clinician-reported adverse event grading to improve pediatric oncology care and research Cancer. 2020 01 01; 126(1):140-147. . View in PubMed
• Validity and Reliability of the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events J Natl Cancer Inst. 2020 11 01; 112(11):1143-1152. . View in PubMed
• Systematic review of barriers and facilitators to clinical trial enrollment among adolescents and young adults with cancer: Identifying opportunities for intervention Cancer. 2020 03 01; 126(5):949-957. . View in PubMed
• Effect of a Daily Text Messaging and Directly Supervised Therapy Intervention on Oral Mercaptopurine Adherence in Children With Acute Lymphoblastic Leukemia: A Randomized Clinical Trial JAMA Netw Open. 2020 08 03; 3(8):e2014205. . View in PubMed
• Emerging Cancer Survival Trends, Disparities, and Priorities in Adolescents and Young Adults: A California Cancer Registry-Based Study JNCI Cancer Spectr. 2019 Jun; 3(2):pkz031. . View in PubMed
• Evaluating and providing quality health information for adolescents and young adults with cancer Pediatr Blood Cancer. 2019 10; 66(10):e27931. . View in PubMed
• Obesity and Risk for Second Malignant Neoplasms in Childhood Cancer Survivors: A Case-Control Study Utilizing the California Cancer Registry Cancer Epidemiol Biomarkers Prev. 2019 10; 28(10):1612-1620. . View in PubMed
• Transitional care practices, services, and delivery in childhood cancer survivor programs: A survey study of US. survivorship providers. Pediatr Blood Cancer. 2019 08; 66(8):e27793. . View in PubMed
• Interventions for cisplatin-induced hearing loss in children and adolescents with cancer Lancet Child Adolesc Health. 2019 08; 3(8):578-584. . View in PubMed
• Understanding, measuring, and addressing the financial impact of cancer on adolescents and young adults Pediatr Blood Cancer. 2019 07; 66(7):e27660. . View in PubMed
• Response to Siegel et al J Natl Cancer Inst. 2019 06 01; 111(6):635-636. . View in PubMed
• A Reappraisal of Sex-Specific Cancer Survival Trends Among Adolescents and Young Adults in the United States J Natl Cancer Inst. 2019 05 01; 111(5):509-518. . View in PubMed
• A comparative analysis of clinicopathological features and survival among early adolescents/young adults and children with low-grade glioma: a report from the Children’s Oncology Group J Neurooncol. 2018 Dec; 140(3):575-582. . View in PubMed
• Prevention of cisplatin-induced hearing loss in children: Informing the design of future clinical trials Cancer Med. 2018 Jul; 7(7):2951-2959. . View in PubMed
• Prevalence and correlates of health information-seeking among Hispanic and non-Hispanic childhood cancer survivors Support Care Cancer. 2018 Apr; 26(4):1305-1313. . View in PubMed
• Cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia and lymphoma: A cross-sectional cohort study using culturally competent, performance-based assessment Pediatr Blood Cancer. 2018 Feb; 65(2). . View in PubMed
• Treatment of young adults with Philadelphia-negative acute lymphoblastic leukemia and lymphoblastic lymphoma: Hyper-CVAD vspediatric-inspired regimens. Am J Hematol. 2018 10; 93(10):1254-1266. . View in PubMed
• Childhood Cancer Survivorship and Substance Use Behaviors: A Matched Case-Control Study Among Hispanic Adolescents and Young Adults J Adolesc Health. 2018 07; 63(1):115-117. . View in PubMed
• Depressive Symptoms and Quality of Life Among Adolescent and Young Adult Cancer Survivors: Impact of Gender and Latino Culture J Adolesc Young Adult Oncol. 2018 06; 7(3):384-388. . View in PubMed
• Child and adolescent self-report symptom measurement in pediatric oncology research: a systematic literature review Qual Life Res. 2018 02; 27(2):291-319. . View in PubMed
• Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy Leuk Lymphoma. 2018 01; 59(1):138-145. . View in PubMed
• Sodium Thiosulfate and Cisplatin-Induced Hearing Loss N Engl J Med. 2018 09 20; 379(12):1180-1. . View in PubMed
• Sexual functioning among young adult cancer patients: A 2-year longitudinal study Cancer. 2018 01 15; 124(2):398-405. . View in PubMed
• Pediatric-Inspired Treatment Regimens for Adolescents and Young Adults With Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Review JAMA Oncol. 2018 05 01; 4(5):725-734. . View in PubMed
• A prospective, observational cohort study comparing cancer clinical trial availability and enrollment between early adolescents/young adults and children Cancer. 2018 03 01; 124(5):983-990. . View in PubMed
• A prospective comparison of cancer clinical trial availability and enrollment among adolescents/young adults treated at an adult cancer hospital or affiliated children’s hospital Cancer. 2018 10 15; 124(20):4064-4071. . View in PubMed
• Treatment strategies for adolescent and young adult patients with acute myeloid leukemia Blood. 2018 07 26; 132(4):362-368. . View in PubMed
• Identifying metrics of success for transitional care practices in childhood cancer survivorship: A qualitative study of survivorship providers Pediatr Blood Cancer. 2017 Nov; 64(11). . View in PubMed
• Long-term follow-up of endocrine function among young children with newly diagnosed malignant central nervous system tumors treated with irradiation-avoiding regimens Pediatr Blood Cancer. 2017 Nov; 64(11). . View in PubMed
• A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia Leuk Lymphoma. 2017 Oct; 58(10):2370-2378. . View in PubMed
• Development of a Culturally Competent Service to Improve Academic Functioning for Latino Survivors of Acute Lymphoblastic Leukemia: Methodological Considerations J Pediatr Oncol Nurs. 2017 May/Jun; 34(3):222-229. . View in PubMed
• Cognitive Interview-Based Validation of the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events in Adolescents with Cancer J Pain Symptom Manage. 2017 04; 53(4):759-766. . View in PubMed
• Eliciting the child’s voice in adverse event reporting in oncology trials: Cognitive interview findings from the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events initiative Pediatr Blood Cancer. 2017 03; 64(3). . View in PubMed
• Supporting long-term follow-up of young adult survivors of childhood cancer: Correlates of healthcare self-efficacy Pediatr Blood Cancer. 2017 02; 64(2):358-363. . View in PubMed
• Group-Wide, Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy (ACCL05C1): A Report From the Children’s Oncology Group J Clin Oncol. 2017 02; 35(4):440-445. . View in PubMed
• Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial Lancet Oncol. 2017 01; 18(1):63-74. . View in PubMed
• Next steps for adolescent and young adult oncology workshop: An update on progress and recommendations for the future Cancer. 2016 Apr 01; 122(7):988-99. . View in PubMed
• Low Enrollment of Adolescents and Young Adults Onto Cancer Trials: Insights From the Community Clinical Oncology Program J Oncol Pract. 2016 Apr; 12(4):e388-95. . View in PubMed
• Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia Bone. 2016 Apr; 85:131-7. . View in PubMed
• Effect of Sensorineural Hearing Loss on Neurocognitive Functioning in Pediatric Brain Tumor Survivors Pediatr Blood Cancer. 2016 Mar; 63(3):527-34. . View in PubMed
• Substance use among adolescent and young adult cancer survivors Psychooncology. 2016 11; 25(11):1357-1362. . View in PubMed
• A parent-directed intervention for addressing academic risk in Latino survivors of childhood leukemia: results of a pilot study Psychooncology. 2016 10; 25(10):1246-1249. . View in PubMed
• Reconsidering Physical Activity Restrictions for Mononephric Survivors of Childhood Cancer: A Report From the Children’s Oncology Group J Pediatr Oncol Nurs. 2016 07; 33(4):306-13. . View in PubMed
• Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children’s Oncology Group Cancer. 2016 06 15; 122(12):1928-36. . View in PubMed
• Case-linked analysis of clinical trial enrollment among adolescents and young adults at a National Cancer Institute-designated comprehensive cancer center Cancer. 2015 Dec 15; 121(24):4398-406. . View in PubMed
• Comparative Toxicity by Sex Among Children Treated for Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group Pediatr Blood Cancer. 2015 Dec; 62(12):2140-9. . View in PubMed
• Enhancing Adolescent and Young Adult Oncology Research Within the National Clinical Trials Network: Rationale, Progress, and Emerging Strategies Semin Oncol. 2015 Oct; 42(5):740-7. . View in PubMed
• Early Cardiac Iron Overload in a Child on Treatment of Acute Lymphoblastic Leukemia Pediatrics. 2015 Sep; 136(3):e697-700. . View in PubMed
• Late Mortality After Dexrazoxane Treatment: A Report From the Children’s Oncology Group J Clin Oncol. 2015 Aug 20; 33(24):2639-45. . View in PubMed
• Inclusion of Adolescents and Young Adults in Cancer Clinical Trials Semin Oncol Nurs. 2015 Aug; 31(3):197-205. . View in PubMed
• The Clinical Trials Gap for Adolescents and Young Adults with Cancer: Recent Progress and Conceptual Framework for Continued Research Curr Pediatr Rep. 2015 Jun; 3(2):137-145. . View in PubMed
• Institutional adherence to cardiovascular risk factor screening guidelines for young survivors of acute lymphoblastic leukemia J Pediatr Hematol Oncol. 2015 May; 37(4):e253-7. . View in PubMed
• Unsanctifying the sanctuary: challenges and opportunities with brain metastases Neuro Oncol. 2015 May; 17(5):639-51. . View in PubMed
• Cancer-related follow-up care among Hispanic and non-Hispanic childhood cancer survivors: The Project Forward study Cancer. 2015 Feb 15; 121(4):605-13. . View in PubMed
• Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia Blood. 2014 Dec 18; 124(26):3932-8. . View in PubMed
• Screening for cardiac dysfunction in anthracycline-exposed childhood cancer survivors Clin Cancer Res. 2014 Dec 15; 20(24):6314-23. . View in PubMed
• Characterization of transfusion-derived iron deposition in childhood cancer survivors Cancer Epidemiol Biomarkers Prev. 2014 Sep; 23(9):1913-9. . View in PubMed
• Pulmonary outcomes in patients with Hodgkin lymphoma treated with involved field radiation Pediatr Blood Cancer. 2014 Jul; 61(7):1277-81. . View in PubMed
• Carnitine and cardiac dysfunction in childhood cancer survivors treated with anthracyclines Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1109-14. . View in PubMed
• Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children’s Oncology Group J Clin Oncol. 2014 May 01; 32(13):1331-7. . View in PubMed
• Comparison of secondary and primary thyroid cancer in adolescents and young adults Cancer. 2014 Apr 15; 120(8):1155-61. . View in PubMed
• Facilitating accrual to cancer control and supportive care trials: the clinical research associate perspective BMC Med Res Methodol. 2013 Dec 31; 13:154. . View in PubMed
• Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the Children’s Oncology Group Cancer. 2013 Dec 01; 119(23):4162-9. . View in PubMed
• Early cardiac outcomes following contemporary treatment for childhood acute myeloid leukemia: a North American perspective Pediatr Blood Cancer. 2013 Sep; 60(9):1528-33. . View in PubMed
• Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation Int J Radiat Oncol Biol Phys. 2013 Aug 01; 86(5):942-8. . View in PubMed
• The first step to integrating the child’s voice in adverse event reporting in oncology trials: a content validation study among pediatric oncology clinicians Pediatr Blood Cancer. 2013 Jul; 60(7):1231-6. . View in PubMed
• Young adults with acute lymphoblastic leukemia treated with a pediatric-inspired regimen do not need a bone marrow transplant in first remission Blood. 2013 Jun 27; 121(26):5253-5. . View in PubMed
• Children’s Oncology Group’s 2013 blueprint for research: adolescent and young adult oncology Pediatr Blood Cancer. 2013 Jun; 60(6):1055-8. . View in PubMed
• Association of projected transfusional iron burden with treatment intensity in childhood cancer survivors Pediatr Blood Cancer. 2012 Oct; 59(4):697-702. . View in PubMed
• Exercise recommendations for childhood cancer survivors exposed to cardiotoxic therapies: an institutional clinical practice initiative J Pediatr Oncol Nurs. 2012 Sep-Oct; 29(5):246-52. . View in PubMed
• Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children’s Oncology Group J Clin Oncol. 2012 Jul 20; 30(21):2641-7. . View in PubMed
• Platinum-induced ototoxicity in children: a consensus review on mechanisms, predisposition, and protection, including a new International Society of Pediatric Oncology Boston ototoxicity scale J Clin Oncol. 2012 Jul 01; 30(19):2408-17. . View in PubMed
• Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach Pediatr Blood Cancer. 2012 Jun; 58(6):953-8. . View in PubMed
• Cancer survivorship practices, services, and delivery: a report from the Children’s Oncology Group (COG) nursing discipline, adolescent/young adult, and late effects committees J Cancer Surviv. 2011 Dec; 5(4):345-57. . View in PubMed
• Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children’s Oncology Group Blood. 2011 Mar 17; 117(11):3010-5. . View in PubMed
• Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches J Clin Oncol. 2010 Nov 10; 28(32):4810-8. . View in PubMed
• Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the children’s oncology group J Clin Oncol. 2009 Nov 01; 27(31):5189-94. . View in PubMed
• Clinical outcomes after long-term treatment with alglucosidase alfa in infants and children with advanced Pompe disease Genet Med. 2009 Mar; 11(3):210-9. . View in PubMed
• Prevention of hearing loss in children receiving cisplatin chemotherapy J Clin Oncol. 2009 Jan 10; 27(2):317-8; author reply 318-9. . View in PubMed
• The effect of cyproheptadine hydrochloride (periactin) and megestrol acetate (megace) on weight in children with cancer/treatment-related cachexia J Pediatr Hematol Oncol. 2008 Nov; 30(11):791-7. . View in PubMed
• Adolescent and young adult oncology: transition of care Pediatr Blood Cancer. 2008 May; 50(5 Suppl):1116-9. . View in PubMed
• Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children’s Oncology Group Blood. 2008 Mar 01; 111(5):2548-55. . View in PubMed
• Measuring the impact of dexrazoxane cardioprotection Pediatr Blood Cancer. 2007 Apr; 48(4):483-4; author reply 485. . View in PubMed
• In sickness and in health: transition of cancer-related care for older adolescents and young adults Cancer. 2006 Oct 01; 107(7 Suppl):1702-9. . View in PubMed
• Multidisciplinary care of the dying adolescent Child Adolesc Psychiatr Clin N Am. 2006 Jul; 15(3):693-715. . View in PubMed
• Models of care for survivors of childhood cancer Pediatr Blood Cancer. 2006 Feb; 46(2):159-68. . View in PubMed
• Flow cytometric diagnosis of X-linked hyper-IgM syndrome: application of an accurate and convenient procedure J Pediatr Hematol Oncol. 2004 Jun; 26(6):363-70. . View in PubMed
• Care of the dying adolescent: special considerations Pediatrics. 2004 Feb; 113(2):381-8. . View in PubMed
• Successful nonoperative management of typhlitis in pediatric oncology patients J Pediatr Surg. 2002 Aug; 37(8):1151-5. . View in PubMed
• Induced hypothermia in experimental pneumococcal meningitis J Cereb Blood Flow Metab. 2000 May; 20(5):834-8. . View in PubMed
• Intravenous methohexital for brief sedation of pediatric oncology outpatients: physiologic and behavioral responses Pediatrics. 1997 May; 99(5):E8. . View in PubMed
• Juvenile xanthogranuloma: forms of systemic disease and their clinical implications J Pediatr. 1996 Aug; 129(2):227-37. . View in PubMed
• Pleuropulmonary blastoma: a marker for familial disease J Pediatr. 1996 Feb; 128(2):220-4. . View in PubMed
• Brief unconscious sedation for painful pediatric oncology proceduresIntravenous methohexital with appropriate monitoring is safe and effective. Am J Pediatr Hematol Oncol. 1993 Nov; 15(4):370-6. . View in PubMed
• Extrarenal Wilms’ tumorUnusual presentation in the lumbosacral region. Am J Pediatr Hematol Oncol. 1993 Feb; 15(1):117-9. . View in PubMed
• Children with cancer: special considerations in the discontinuation of life-sustaining treatment Med Pediatr Oncol. 1992; 20(2):136-42. . View in PubMed
• Regulation of superoxide responses of human neutrophils by adenine compoundsIndependence of requirement for cytoplasmic granules. Lab Invest. 1989 Nov; 61(5):515-21. . View in PubMed
• Surface Mo1 (CD11b/CD18) glycoprotein is up-modulated by neutrophils recruited to sites of inflammation in vivo Inflammation. 1989 Oct; 13(5):495-505. . View in PubMed
• Primary primitive neuroectodermal tumor of the spinal cord associated with neural tube defect Pediatr Neurosci. 1989; 15(4):181-7. . View in PubMed
• Stimulation of human neutrophil adhesive properties by adenine nucleotides J Immunol. 1988 Jul 15; 141(2):580-6. . View in PubMed
• The CD11/CD18 leukocyte glycoprotein deficiency Hematol Oncol Clin North Am. 1988 Mar; 2(1):13-31. . View in PubMed
• Modulation of surface CD11/CD18 glycoproteins (Mo1, LFA-1, p150,95) by human mononuclear phagocytes Clin Immunol Immunopathol. 1988 Feb; 46(2):272-83. . View in PubMed

• Orgel, Etan
• Wiemels, Joseph
• Lenz, Heinz-Josef
• Hamilton, Ann
• Gaynon, Paul
• Wood, John