Donald B Longjohn, MD

Assistant Professor of Clinical Orthopaedic Surgery

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Dr. Longjohn is an assistant professor in the Department of Orthopaedic Surgery at the Keck School of Medicine of USC. He specializes in hip and knee replacement/revision surgery, as well as arthritis, rheumatoid arthritis, osteoarthritis and arthroscopic surgery. In addition to his membership in professional organizations such as American Association of Hip and Knee Surgeons and the Western Orthopaedic Association, Dr. Longjohn is a member of the LA County Sheriff’s Department Medical Reserve Company 206 (Office of Homeland Security) and also volunteers as a flight physician for the LA County Sheriff’s Department Air Rescue 5. Dr. Longjohn has been honored with several teaching awards. His current research focus is on clinical and biomechanical studies relating to joint replacement and arthroplasty revision techniques and materials. Dr. Longjohn did his residency in orthopaedic surgery at USC+LAC and completed a fellowship in arthritis and joint implant surgery at Rancho Los Amigos National Rehabilitation Center/Keck Hospital of USC.


  • Los Angeles Magazine: Super Doctor, 2016-2022
  • Castle Connolly: Amreica’s Top Doctors, 2016


  • Limited Durability of Extensor Mechanism Reconstruction Following Total Knee Arthroplasty: Mesh and Allograft Show Equivalent Outcomes at Five-Year Follow-Up J Arthroplasty. 2024 Mar; 39(3):772-777. . View in PubMed
  • Metal artifact reduction sequence-MRI abnormalities in asymptomatic patients with dual-mobility hip prostheses Bone Joint J. 2024 Mar 01; 106-B(3 Supple A):89-96. . View in PubMed
  • A double-blinded, placebo-controlled, randomized study to evaluate the efficacy of perioperative dextromethorphan compared to placebo for the treatment of postoperative pain: a study protocol Trials. 2023 Mar 29; 24(1):238. . View in PubMed
  • Refining the Role of Routine Synovial Alpha-Defensin in Periprosthetic Joint Infection Following Total Knee Arthroplasty: An Analysis of Limitations J Arthroplasty. 2023 12; 38(12):2691-2697. . View in PubMed
  • Factors Associated With Failure Following Proximal Femoral Replacement for Salvage Hip Surgery for Nononcologic IndicationsJ Arthroplasty. 2023 11; 38(11):2429-2435. e2. . View in PubMed
  • Influence of donor age and comorbidities on transduced human adipose-derived stem cell in vitro osteogenic potential Gene Ther. 2023 04; 30(3-4):369-376. . View in PubMed
  • Modern Proximal Femoral Replacement in Revision Total Hip Arthroplasty for Nononcologic Indications J Arthroplasty. 2022 08; 37(8S):S958-S963. . View in PubMed
  • The insidious risk of periprosthetic fracture in clinically functional total hip arthroplasties: A biomechanical study of willed joints J Orthop Res. 2022 08; 40(8):1943-1952. . View in PubMed
  • Outcomes of an Institutional Rapid Recovery Protocol for Total Joint Arthroplasty at a Safety Net Hospital J Am Acad Orthop Surg Glob Res Rev. 2022 03 09; 6(3). . View in PubMed
  • Implementation of an enhanced recovery protocol at a safety net hospital : a silver lining to COVID-19? Bone Jt Open. 2021 Oct; 2(10):871-878.. View in PubMed
  • Patient Perception Regarding the Safety of Elective Joint Arthroplasty Surgery During the COVID-19 Pandemic Arthroplast Today. 2021 Oct; 11:113-121. . View in PubMed
  • Anterior Total Hip Arthroplasty With Bulk Femoral Head Autograft in a Patient With Camurati-Engelmann Disease Arthroplast Today. 2021 Apr; 8:204-210. . View in PubMed
  • Limited potential of AAV-mediated gene therapy in transducing human mesenchymal stem cells for bone repair applications Gene Ther. 2021 12; 28(12):729-739. . View in PubMed
  • Regional gene therapy for bone healing using a 3D printed scaffold in a rat femoral defect model J Biomed Mater Res A. 2021 11; 109(11):2346-2356. . View in PubMed
  • Regional Gene Therapy with Transduced Human Cells: The Influence of “Cell Dose” on Bone Repair Tissue Eng Part A. 2021 11; 27(21-22):1422-1433. . View in PubMed
  • Periprosthetic femoral bone loss in total hip arthroplasty: systematic analysis of the effect of stem design Hip Int. 2017 Feb 21; 27(1):26-34. . View in PubMed
  • Systematic analysis of bisphosphonate intervention on periprosthetic BMD as a function of stem design J Arthroplasty. 2014 Jun; 29(6):1292-7. . View in PubMed
  • Challenges in relating experimental hip implant fixation predictions to clinical observations J Biomech. 2011 Jan 11; 44(2):235-43. . View in PubMed
  • The influence of proximal stem geometry and surface finish on the fixation of a double-tapered cemented femoral stem J Biomech. 2011 Jan 04; 44(1):22-7. . View in PubMed
  • Simulation of extreme loads on the proximal femur for implant fixation assessment J Appl Biomater Biomech. 2008 May-Aug; 6(2):72-80. . View in PubMed
  • Effects of dorsal flanges on fixation of a cemented total hip replacement femoral stem J Bone Joint Surg Am. 2004 Apr; 86(4):813-20. . View in PubMed
  • Initial stability of cemented femoral stems as a function of surface finish, collar, and stem size J Bone Joint Surg Am. 2004 Jan; 86(1):106-15. . View in PubMed
  • Effects of total hip arthroplasty cemented femoral stem surface finish, collar and cement thickness on load transfer to the femur J Appl Biomater Biomech. 2003 Jan-Apr; 1(1):76-83. . View in PubMed
  • Technical factors for success with metal ring acetabular reconstruction J Arthroplasty. 2001 Dec; 16(8):961-9. . View in PubMed
  • Radiographic comparison of diaphyseal grit blasted with smooth surface stems by matched pair analysis Clin Orthop Relat Res. 2000 Dec; (381):156-67. . View in PubMed
  • Total hip arthroplasty with use of the Metasul metal-on-metal articulationFour to seven-year results. J Bone Joint Surg Am. 2000 Jun; 82(6):789-98. . View in PubMed
  • Blood management challenges in revision hip arthroplasty Orthopedics. 1999 Jan; 22(1 Suppl):s148-50. . View in PubMed
  • Soft tissue balance of the hip J Arthroplasty. 1998 Jan; 13(1):97-100. . View in PubMed
  • Acute hematogenous osteomyelitis of the epiphysis Clin Orthop Relat Res. 1995 Jul; (316):227-34. . View in PubMed