Edward David Crandall, PhD, MD

Dr. Crandall’s research has been focused on the following topics: markers of alveolar epithelial cell development and differentiation, regulation of pulmonary epithelial cell differentiation, acute and chronic lung injury and the factors that influence recovery, transport properties of pulmonary alveolar epithelium, and biology of nanoparticle interactions with alveolar epithelial cells.

Dr. Crandall received his B.Ch.E. from Cooper Union, his M.S. and Ph.D. in chemical engineering from Northwestern University, and his M.D. from the University of Pennsylvania. His training in internal medicine and pulmonary/critical care medicine was undertaken at the Hospital of the University of Pennsylvania.

• Best Doctors of America, 2005
   – Pres
• National Institutes of Health: MERIT Award, 1987
   – 1997
• National Institutes of Health: Research Career Development Award, 1975
   – 1980
• University of Pennsylvania: Chair of Department of Medicine Scholarship
• U.S. Public Health Service: Special Fellowship
• National Science Foundation: Graduate Fellowship
• New York State: Regents Scholarship

• MAPGen Knowledge Base (MAPGenKB) and Coordination Center
  NIH · U01HL108634 · Aug 25, 2011 – May 31, 2018 · Role: Co-Principal Investigator
• Interactions of engineered nanomaterials with lung alveolar epithelium
  NIH · RC2ES018782 · Sep 25, 2009 – Jun 30, 2012 · Role: Principal Investigator
• Nanoparticle properties and alveolar epithelial barrier/transport functions
  NIH · R01ES017034 · Jun 15, 2009 – Mar 31, 2015 · Role: Principal Investigator
• Absorption mechanisms for peptide/protein drugs via lung
  NIH · R01HL064365 · Sep 30, 1999 – Jul 31, 2010 · Role: Principal Investigator
• AT1 vs AT2 cells: differential roles in alveolar function and biology
  NIH · R01HL038621 · Sep 1, 1986 – Jun 30, 2012 · Role: Principal Investigator
• GATA-6: Key Regulator of AEC Transdifferentiation
  NIH · R01HL038578 · Sep 1, 1986 – Nov 30, 2008 · Role: Co-Principal Investigator
• LUNG EPITHELIAL TRANSPORT PROPERTIES AND ALVEOLAR EDEMA
  NIH · R37HL038578 · Sep 1, 1986 – Aug 31, 1997 · Role: Principal Investigator
• DETERMINANTS OF LUNG AND TISSUE CO2 EXCHANGE AND TRANSPO
  NIH · R01HL025669 · Aug 1, 1980 – Aug 31, 1986 · Role: Principal Investigator
• LUNG EPITHELIAL TRANSPORT PROPERTIES AND ALVEOLAR EDEMA
  NIH · R01HL026223 · Aug 1, 1980 – Aug 31, 1986 · Role: Principal Investigator

• Minoo, Parviz
• Zhou, Beiyun
• Kim, Kwang
• Sipos, Arnold
• McDonough, Alicia
• Hamm-Alvarez, Sarah