Eyal Ben-Isaac, MD

Professor of Clinical Pediatrics (Educational Scholar)

Image of Eyal Ben-Isaac, MD
Is this your profile? Click to edit


Eyal Ben-Isaac is an Assistant Professor in Clinical Pediatrics at the USC Keck School of Medicine. He completed his pediatric residency training at Children’s Hospital Los Angeles (CHLA) in 1992, and has continued to maintain a practice (inpatient and outpatient) in the Division of General Pediatrics. He has also been the Pediatric Residency Program Director at CHLA since 1994, supervising the training of approximately 85 residents each year.

Dr. Ben-Isaac lectures throughout the year to both CHLA pediatric housestaff and medical students from the USC Keck School of Medicine. He has developed a large portfolio of lecture topics, and has been instrumental in the development of the overall educational curriculum. He has developed several educational tools used by the residency program including Objective Structured Clinical Exams, a Pediatric Board Review course, a general pediatric educational CD-Rom, a web portal, on-line learning modules, and General Pediatric competency exams.

Dr. Ben-Isaac has been recognized for his contributions with both teaching and clinical awards. These include the Philip E. Rothman Teaching Award, the Barbara Korsch Excellence in Medical Education Award, Morris and Mary Press Humanism Award, and a number of Top Doctor honors.

Dr. Ben-Isaac has an interest in education and general pediatrics. He has been an invited speaker and has published articles on such related topics. His current interests involve the impact of restricted duty hours for trainees and the development of teaching modalities to maintain competency. He is also currently involved in the development of new educational curriculums as well as a Simulation Center at CHLA.


  • BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures Nucleic Acids Res. 2023 09 22; 51(17):9369-9384. . View in PubMed
  • Lessons learned from organizing and evaluating international virtual training for healthcare professionals Int J Med Educ. 2022 03 31; 13:88-89. . View in PubMed
  • When the Physician Becomes the Caregiver: A Review for Physicians Caring for Their Elder Relatives Pediatr Rev. 2021 08; 42(8):405-413. . View in PubMed
  • TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment Proc Natl Acad Sci U S A. 2021 06 08; 118(23). . View in PubMed
  • Persistent Toe-Walking in a Developmentally Normal 7-year-old Girl Pediatr Rev. 2020 Oct; 41(Suppl 1):S3-S5. . View in PubMed
  • Case 1: Progressive Dysphagia in a Teenager with Down Syndrome Pediatr Rev. 2020 05; 41(5):245-248. . View in PubMed
  • Satisfaction, Salaries, and Sustainability: Results of a National Survey of Pediatric Program Directors Acad Pediatr. 2019 Jan – Feb; 19(1):11-17. . View in PubMed
  • Peer-Debriefing After Distressing Patient Care Events: A Workshop for Pediatric Residents MedEdPORTAL. 2017 09 05; 13:10624. . View in PubMed
  • Modeling the dynamics of a tracer particle in an elastic active gel Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Jul; 92(1):012716. . View in PubMed
  • Index of suspicionCase 1: Anasarca in a 2-year-old boy. Case 2: Daily spiking fevers in an 8-year-old girl. Case 3: Poor weight gain and excessive sleepiness in a 7-week-old girl. Pediatr Rev. 2014 Jan; 35(1):42-7. . View in PubMed
  • Assessing the utility of procedural training for pediatrics residents in general pediatric practice J Grad Med Educ. 2013 Mar; 5(1):88-92. . View in PubMed
  • Case 1: Why does my eye keep turning in? Paediatr Child Health. 2012 Apr; 17(4):198-9.. View in PubMed
  • Effective temperature of red-blood-cell membrane fluctuations Phys Rev Lett. 2011 Jun 10; 106(23):238103. . View in PubMed
  • Case 2: Where have all the white cells gone? Paediatr Child Health. 2010 Nov; 15(9):577-80.. View in PubMed
  • National profile of nonemergent pediatric emergency department visits Pediatrics. 2010 Mar; 125(3):454-9. . View in PubMed