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Francisco A Gonzalez-Scarano

Clinical Professor of Neurology (Part-Time)

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Email [email protected]
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Publications

  • Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. J Clin Invest. 2011 Nov; 121(11):4433-45.. View in PubMed
  • Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008. J Neuroimmune Pharmacol. 2009 Sep; 4(3):283-97.. View in PubMed
  • HIV-associated neuropathies: role of HIV-1, CMV, and other viruses. J Peripher Nerv Syst. 2001 Mar; 6(1):2-7.. View in PubMed
  • Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp Mol Pathol. 2000 Dec; 69(3):192-201.. View in PubMed
  • Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease. AJNR Am J Neuroradiol. 1996 Sep; 17(8):1539-47.. View in PubMed
  • Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention. J Virol. 1996 Aug; 70(8):5329-35.. View in PubMed
  • Tropism of bunyaviruses: evidence for a G1 glycoprotein-mediated entry pathway common to the California serogroup. Virology. 1995 Dec 20; 214(2):339-48.. View in PubMed
  • Sodium butyrate stimulation of HIV-1 gene expression: a novel mechanism of induction independent of NF-kappa B. J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 01; 9(4):332-9.. View in PubMed
  • Protection from La Crosse virus encephalitis with recombinant glycoproteins: role of neutralizing anti-G1 antibodies. J Virol. 1995 Jun; 69(6):3475-81.. View in PubMed
  • Completion of the La Crosse virus genome sequence and genetic comparisons of the L proteins of the Bunyaviridae. Virology. 1995 Jan 10; 206(1):742-5.. View in PubMed
  • Magnetization transfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhanced spin-echo images and nonenhanced T1-weighted images. AJNR Am J Neuroradiol. 1995 Jan; 16(1):69-77.. View in PubMed
  • Synthetic multimeric peptides derived from the principal neutralization domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 bind to galactosylceramide and block HIV-1 infection in a human CD4-negative mucosal epithelial cell line. J Virol. 1995 Jan; 69(1):320-5.. View in PubMed
  • Interferon-gamma decreases cell surface expression of galactosyl ceramide, the receptor for HIV-1 GP120 on human colonic epithelial cells. Virology. 1994 Nov 01; 204(2):550-7.. View in PubMed
  • Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells. J Biol Chem. 1994 Sep 30; 269(39):24349-53.. View in PubMed
  • GalCer, CD26 and HIV infection of intestinal epithelial cells. AIDS. 1994 Sep; 8(9):1347-8.. View in PubMed
  • Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis. Magn Reson Med. 1994 Sep; 32(3):285-93.. View in PubMed
  • Human immunodeficiency virus type 1 Tat activity in human neuronal cells: uptake and trans-activation. J Gen Virol. 1994 Aug; 75 ( Pt 8):1927-34.. View in PubMed
  • Pathogenesis of HIV encephalopathy. Ann N Y Acad Sci. 1994 Jun 06; 724:87-106.. View in PubMed
  • Replication in cultured C2C12 muscle cells correlates with the neuroinvasiveness of California serogroup bunyaviruses. Virology. 1994 Jun; 201(2):399-403.. View in PubMed
  • Binding of human immunodeficiency virus type I (HIV-1) gp120 to galactosylceramide (GalCer): relationship to the V3 loop. Virology. 1994 Jun; 201(2):206-14.. View in PubMed
  • Human immunodeficiency virus type 1 causes productive infection of macrophages in primary placental cell cultures. J Infect Dis. 1994 Apr; 169(4):746-53.. View in PubMed
  • Monoclonal anti-idiotypic antibodies that mimic the epitope on gp120 defined by anti-HIV-1 monoclonal antibody 0.5 beta. AIDS. 1993 Dec; 7(12):1553-9.. View in PubMed
  • Replication of a macrophage-tropic strain of human immunodeficiency virus type 1 (HIV-1) in a hybrid cell line, CEMx174, suggests that cellular accessory molecules are required for HIV-1 entry. J Virol. 1993 Nov; 67(11):6707-15.. View in PubMed
  • Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. Virology. 1993 Oct; 196(2):496-505.. View in PubMed
  • HIV-1 pseudotype virus containing a Cocal virus genome and an HIV envelope: construction, assay and use. J Virol Methods. 1993 Oct; 44(2-3):287-304.. View in PubMed
  • HIV-1 Tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence. AIDS Res Hum Retroviruses. 1993 Jul; 9(7):677-85.. View in PubMed
  • Polygenic control of neuroinvasiveness in California serogroup bunyaviruses. J Virol. 1993 Jul; 67(7):3861-7.. View in PubMed
  • Expression of the La Crosse M segment proteins in a recombinant vaccinia expression system mediates pH-dependent cellular fusion. Virology. 1993 Apr; 193(2):993-6.. View in PubMed
  • Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):2700-4.. View in PubMed
  • Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to -130 region of the long terminal repeat. J Virol. 1993 Mar; 67(3):1658-62.. View in PubMed
  • Molecular determinants of the virulence and infectivity of California serogroup bunyaviruses. Annu Rev Microbiol. 1993; 47:117-38.. View in PubMed
  • Infection of cultured human adrenal cells by different strains of HIV. AIDS. 1992 Dec; 6(12):1437-43.. View in PubMed
  • MR proton spectroscopy in multiple sclerosis. AJNR Am J Neuroradiol. 1992 Nov-Dec; 13(6):1535-43.. View in PubMed
  • Genetics, infectivity and virulence of California serogroup viruses. Virus Res. 1992 Jul; 24(2):123-35.. View in PubMed
  • Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology. 1992 Feb; 182(2):483-91.. View in PubMed
  • Neuroattenuation of an avirulent bunyavirus variant maps to the L RNA segment. J Virol. 1991 Oct; 65(10):5465-70.. View in PubMed
  • Galactosyl ceramide or a derivative is an essential component of the neural receptor for human immunodeficiency virus type 1 envelope glycoprotein gp120. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7131-4.. View in PubMed
  • Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide. Science. 1991 Jul 19; 253(5017):320-3.. View in PubMed
  • Entry of human immunodeficiency virus-1 into glial cells proceeds via an alternate, efficient pathway. J Leukoc Biol. 1991 Jun; 49(6):605-9.. View in PubMed
  • Bunyaviridae: Pathogenesis. Curr Top Microbiol Immunol. 1991; 169:217-49.. View in PubMed
  • Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor. J Virol. 1990 Sep; 64(9):4468-76.. View in PubMed
  • Neuroattenuated bunyavirus variant: derivation, characterization, and revertant clones. J Virol. 1990 May; 64(5):1927-33.. View in PubMed
  • CD4-independent infection of human neural cells by human immunodeficiency virus type 1. J Virol. 1989 Jun; 63(6):2527-33.. View in PubMed
  • Human immunodeficiency virus can infect CD4-negative human fibroblastoid cells. Proc Natl Acad Sci U S A. 1989 Jun; 86(11):4287-90.. View in PubMed
  • Human choroid plexus cells can be latently infected with human immunodeficiency virus. Ann Neurol. 1989 Apr; 25(4):406-11.. View in PubMed
  • Human immunodeficiency virus: an agent that defies vaccination. Adv Vet Sci Comp Med. 1989; 33:397-412.. View in PubMed
  • The large viral RNA segment of California serogroup bunyaviruses encodes the large viral protein. J Gen Virol. 1989 Jan; 70 ( Pt 1):223-8.. View in PubMed
  • Organization of the middle RNA segment of snowshoe hare Bunyavirus. Virology. 1988 Dec; 167(2):422-32.. View in PubMed
  • Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. Radiology. 1988 Oct; 169(1):117-22.. View in PubMed
  • Genetic determinants of the virulence and infectivity of La Crosse virus. Microb Pathog. 1988 Jan; 4(1):1-7.. View in PubMed
  • Molecular pathogenesis of neurotropic viral infections. Ann Neurol. 1987 Nov; 22(5):565-74.. View in PubMed
  • Multiple sclerosis disease activity correlates with gadolinium-enhanced magnetic resonance imaging. Ann Neurol. 1987 Mar; 21(3):300-6.. View in PubMed
  • A G1 glycoprotein epitope of La Crosse virus: a determinant of infection of Aedes triseriatus. Science. 1987 Jan 30; 235(4788):591-3.. View in PubMed
  • Sequence similarities between human immunodeficiency virus gp41 and paramyxovirus fusion proteins. AIDS Res Hum Retroviruses. 1987; 3(3):245-52.. View in PubMed
  • Multiple sclerosis: gadolinium enhancement in MR imaging. Radiology. 1986 Dec; 161(3):721-5.. View in PubMed
  • Biological studies of the fusion function of California serogroup Bunyaviruses. Microb Pathog. 1986 Oct; 1(5):491-501.. View in PubMed
  • Virulence of La Crosse virus is under polygenic control. J Virol. 1986 Jul; 59(1):1-7.. View in PubMed
  • Epitopes of the G1 glycoprotein of La Crosse virus form overlapping clusters within a single antigenic site. Virology. 1985 Jul 30; 144(2):426-32.. View in PubMed
  • An avirulent G1 glycoprotein variant of La Crosse bunyavirus with defective fusion function. J Virol. 1985 Jun; 54(3):757-63.. View in PubMed
  • La Crosse virus G1 glycoprotein undergoes a conformational change at the pH of fusion. Virology. 1985 Jan 30; 140(2):209-16.. View in PubMed
  • Mechanisms of bunyavirus virulence. Comparative pathogenesis of a virulent strain of La Crosse and an avirulent strain of Tahyna virus. Lab Invest. 1984 Apr; 50(4):447-55.. View in PubMed
  • La Crosse bunyavirus can mediate pH-dependent fusion from without. Virology. 1984 Jan 15; 132(1):222-5.. View in PubMed
  • Monoclonal antibodies against the G1 and nucleocapsid proteins of LaCrosse and Tahyna viruses. Prog Clin Biol Res. 1983; 123:145-56.. View in PubMed
  • Characterization of monoclonal antibodies against the G1 and N proteins of LaCrosse and Tahyna, two California serogroup bunyaviruses. Virology. 1982 Jul 15; 120(1):42-53.. View in PubMed
  • Primary epiduritis. Hum Pathol. 1981 Jul; 12(7):673-5.. View in PubMed
  • Cranial computed tomography in the diagnosis of systemic lupus erythematosus. Ann Neurol. 1979 Feb; 5(2):158-65.. View in PubMed
  • Central nervous system immunity in mice infected with theiler’s virus. I. Local neutralizing antibody response. J Infect Dis. 1978 Feb; 137(2):145-51.. View in PubMed