Keck School Faculty

Fred A Weaver, MD
Fred A Weaver, MD
Professor of Surgery;Division Chief, Vascular Surgery
Surgery
HCT 1520 San Pablo St., Suite 4300 Health Sciences Campus Los Angeles
Dr. Fred Arthur Weaver holds the title of Professor of Surgery at the Keck School of Medicine of the University of Southern California (USC). Dr. Weaver's education includes a Bachelor of Science (1975) and Doctor of Medicine (1979) degrees from USC. He also has a Masters in Medical Management, which he received from USC in 2005. He received his surgical training at Vanderbilt University Medical Center in Nashville, Tennessee where he served as a Resident in General Surgery 1979-84, a Chief Resident in General Surgery 1984-85 and a Vascular Surgery Fellow 1985-86. He then returned to USC in 1986 as an Assistant Professor of Surgery, and promoted to Professor of Surgery in 1999. In 1990 and again, in 1993, he received the C.J. Berne Award for Teaching Excellence from the USC surgical residents.

He served as Program Director for General Surgery from 1996-2000 and as Program Director for Vascular Surgery at USC since its inception in 1999. He is the Director of the Max R. Gaspar Symposium, an annual meeting, which highlights advances in the treatment of vascular disease. He is currently the Co-Director of the USC CardioVascular Thoracic Institute and the Chief of Vascular Surgery and Endovascular Therapy at USC.

Dr. Weaver is certified by the American Board of Surgery in Vascular Surgery and General Surgery. He is a member of the Society for Vascular Surgery, American Surgical Association, a Fellow of the American College of Surgeons, and Past President of the Western Vascular Society, Pacific Coast Surgical Association and Society for Clinical Vascular Surgery. Dr. Weaver is currently an Associate Editor for the Journal of Vascular Surgery and on the Editorial Board of the Annals of Vascular Surgery. He recently was an Associate Editor of Rutherford's Vascular Surgery. He has been recognized as one of the Best Doctors in America since 2005, and a Southern California Super Doctor since 2008. His major research interest concerns the diagnosis and management of diseases which affect the aorta and its major branches with an emphasis on aortic and renal artery disease. These research efforts are complemented by an active and diverse clinical practice at the Keck Hospital of USC where he performs both endovascular and open reconstructive aortic procedures.

Management of a Large Abdominal Aortic Aneurysm in Conjunction with a Massive Inguinal HerniaAnn Vasc Surg. 2017 Jul; 42:302. e7-302. e10. . View in PubMed

Repair of Delayed Type 1a Endoleak using Fenestrated and Parallel EndograftsAnn Vasc Surg. 2018 May; 49:309. e7-309. e15. . View in PubMed

Lift sandwich grafting enables transfemoral abdominal aortic branch incorporation during endovascular aortic repair for chronic type B aortic dissection Ann Vasc Surg. 2019 Jan 23. . View in PubMed

Focused Resident Education and Engagement in Quality Improvement Enhances Documentation, Shortens Hospital Length of Stay, and Creates a Culture of Continuous Improvement J Surg Educ. 2018 Dec 12. . View in PubMed

Impact of proximal seal zone length and intramural hematoma on clinical outcomes and aortic remodeling after thoracic endovascular aortic repair for aortic dissections J Vasc Surg. 2018 Oct 24. . View in PubMed

Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices Catheter Cardiovasc Interv. 2018 Oct 01; 92(4):743-749. . View in PubMed

First granted example of novel FDA trial design under Expedited Access Pathway for premarket approval: BeAT-HF Am Heart J. 2018 Oct; 204:139-150. . View in PubMed

Baroreflex activation therapy for the treatment of heart failure with reduced ejection fraction in patients with and without coronary artery disease Int J Cardiol. 2018 Sep 01; 266:187-192. . View in PubMed

First granted example of novel FDA trial design under Expedited Access Pathway for premarket approval: BeAT-HF Am Heart J. 2018 Jul 22; 204:139-150. . View in PubMed

Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices Catheter Cardiovasc Interv. 2018 Jul 18. . View in PubMed

Cardiac and Vascular Surgery-Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group J Am Heart Assoc. 2018 Jun 01; 7(11). . View in PubMed

Postoperative Development of Abdominal Compartment Syndrome among Patients Undergoing Endovascular Aortic Repair for Ruptured Abdominal Aortic Aneurysms Ann Vasc Surg. 2018 May; 49:289-294. . View in PubMed

Baroreflex activation therapy for the treatment of heart failure with reduced ejection fraction in patients with and without coronary artery disease Int J Cardiol. 2018 Apr 21. . View in PubMed

Invited commentary J Vasc Surg. 2018 08; 68(2):517-518. . View in PubMed

Challenge and Yield of Enrolling Racially and Ethnically Diverse Patient Populations in Low Event Rate Clinical Trials Stroke. 2018 01; 49(1):84-89. . View in PubMed

Association of left subclavian artery coverage without revascularization and spinal cord ischemia in patients undergoing thoracic endovascular aortic repair: A Vascular Quality Initiative® analysis Vascular. 2017 Dec; 25(6):587-597. . View in PubMed

Comparison of intravascular ultrasound- and centerline computed tomography-determined aortic diameters during thoracic endovascular aortic repair J Vasc Surg. 2017 Oct; 66(4):1184-1191. . View in PubMed

Computerized tomography angiography by direct intra-aortic low volume contrast injection in patients being evaluated for EVAR Vascular. 2017 Oct; 25(5):451-458. . View in PubMed

Invited commentary J Vasc Surg. 2017 Aug; 66(2):342. . View in PubMed

Multilayered Parallel Endografting for Urgent Endovascular Repair of a Severely Angulated Thoracoabdominal Aortic Aneurysm Ann Vasc Surg. 2017 Jul; 42:56-61. . View in PubMed

Increased risk of mortality after lower extremity bypass in individuals with acute kidney injury in the Vascular Quality Initiative J Vasc Surg. 2017 Apr; 65(4):1055-1061. . View in PubMed

Comparison of intravascular ultrasound- and centerline computed tomography-determined aortic diameters during thoracic endovascular aortic repair J Vasc Surg. 2017 10; 66(4):1184-1191. . View in PubMed

Invited commentary J Vasc Surg. 2017 08; 66(2):342. . View in PubMed

Management of patients with acute aortic syndrome through a regional rapid transport system J Vasc Surg. 2017 Jan; 65(1):21-29. . View in PubMed

Natriuretic Peptides, 6-Min Walk Test, and Quality-of-Life Questionnaires as Clinically Meaningful Endpoints in HF Trials J Am Coll Cardiol. 2016 Dec 20; 68(24):2690-2707. . View in PubMed

Remodeling of abdominal aortic branch perfusion after thoracic endovascular aortic repair for aortic dissections J Vasc Surg. 2016 Oct; 64(4):902-11. . View in PubMed

Remodeling of abdominal aortic branch perfusion after thoracic endovascular aortic repair for aortic dissections J Vasc Surg. 2016 10; 64(4):902-11. . View in PubMed

Baroreflex activation therapy for the treatment of heart failure with a reduced ejection fraction: safety and efficacy in patients with and without cardiac resynchronization therapy Eur J Heart Fail. 2015 Oct; 17(10):1066-74. . View in PubMed

Regional Quality Groups Enhance Effectiveness of Vascular Quality Initiative® Am Surg. 2015 Oct; 81(10):995-9. . View in PubMed

Outcomes of completion imaging for lower extremity bypass in the Vascular Quality Initiative J Vasc Surg. 2015 Aug; 62(2):412-6. . View in PubMed

Baroreflex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction JACC Heart Fail. 2015 Jun; 3(6):487-496. . View in PubMed

Bilateral cervical ribs causing cerebellar stroke and arterial thoracic outlet syndrome: a case report and review of the literatureAnn Vasc Surg. 2015 May; 29(4):840. e1-4. . View in PubMed

Renal Denervation in Heart Failure Curr Hypertens Rep. 2015 Mar; 17(3):17. . View in PubMed

Resistant hypertension: medical management and alternative therapies Cardiol Clin. 2015 Feb; 33(1):75-87. . View in PubMed

Identification of a high-risk subset of patients undergoing infrainguinal bypass surgery JAMA Surg. 2015 Jan; 150(1):82-4. . View in PubMed

Disruptive technology and the making of contemporary vascular surgery J Vasc Surg. 2014 Nov; 60(5):1376-82. . View in PubMed

Compliance with surgical follow-up does not influence fistula maturation in a county hospital population Ann Vasc Surg. 2014 Nov; 28(8):1847-52. . View in PubMed

Disruptive technology and the making of contemporary vascular surgery J Vasc Surg. 2014 Nov; 60(5):1376-1382. . View in PubMed

Bilateral renal artery involvement of erdheim-chester diseaseAnn Vasc Surg. 2014 Oct; 28(7):1793. e15-8. . View in PubMed

Outcomes after abdominal aortic aneurysm repair requiring a suprarenal cross-clamp J Vasc Surg. 2014 Oct; 60(4):893-9. . View in PubMed

Aortic morphologic findings after thoracic endovascular aortic repair for type B aortic dissection JAMA Surg. 2014 Sep; 149(9):977-83. . View in PubMed

Outcomes with arteriovenous fistulas in a pediatric population J Vasc Surg. 2014 Jul; 60(1):170-4. . View in PubMed

Ex vivo renal artery reconstruction for complex renal artery disease J Vasc Surg. 2014 Jul; 60(1):143-50. . View in PubMed

Basic data related to thrombolytic therapy for acute venous thrombosis Ann Vasc Surg. 2014 May; 28(4):1039-44. . View in PubMed

Abdominal aortic resection and Y-graft placement to achieve complete cytoreduction in stage IIIc ovarian carcinoma Obstet Gynecol. 2014 Feb; 123(2 Pt 2 Suppl 2):486-8. . View in PubMed

Endoscopic vein harvest for infrainguinal arterial bypass J Vasc Surg. 2013 Jun; 57(6):1489-94. . View in PubMed

Regional quality groups in the Society for Vascular Surgery® Vascular Quality Initiative J Vasc Surg. 2013 Mar; 57(3):884-90. . View in PubMed

A prospective study of carbon dioxide digital subtraction versus standard contrast arteriography in the detection of endoleaks in endovascular abdominal aortic aneurysm repairs Ann Vasc Surg. 2013 Jan; 27(1):38-44. . View in PubMed

Development of a flexible implantable sensor for postoperative monitoring of blood flow J Ultrasound Med. 2012 Nov; 31(11):1795-802. . View in PubMed

Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at standard surgical risk: results from the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) Stroke. 2012 Sep; 43(9):2408-16. . View in PubMed

Restenosis after carotid artery stenting and endarterectomy: a secondary analysis of CREST, a randomised controlled trial Lancet Neurol. 2012 Sep; 11(9):755-63. . View in PubMed

Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues Biochem Biophys Res Commun. 2012 Feb 03; 418(1):173-9. . View in PubMed

Basic data related to thrombolytic therapy for acute arterial thrombosis Ann Vasc Surg. 2012 Feb; 26(2):292-7. . View in PubMed

Disease progression after initial surgical intervention for Takayasu arteritis J Vasc Surg. 2011 Nov; 54(5):1345-51. . View in PubMed

Health-related quality of life after carotid stenting versus carotid endarterectomy: results from CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) J Am Coll Cardiol. 2011 Oct 04; 58(15):1557-65. . View in PubMed

Arch and visceral/renal debranching combined with endovascular repair for thoracic and thoracoabdominal aortic aneurysms J Vasc Surg. 2011 Jul; 54(1):30-40; discussion 40-1. . View in PubMed

Commentary on "A modern approach to cervical vascular injuries" Perspect Vasc Surg Endovasc Ther. 2011 Jun; 23(2):98-9. . View in PubMed

Clinical outcomes and implications of failed infrainguinal endovascular stents J Vasc Surg. 2011 Mar; 53(3):658-66; discussion 667. . View in PubMed

Impact of race on infrainguinal angioplasty and stenting Ann Vasc Surg. 2011 Feb; 25(2):204-9. . View in PubMed

Chronic baroreflex activation: a potential therapeutic approach to heart failure with preserved ejection fraction J Card Fail. 2011 Feb; 17(2):167-78. . View in PubMed

A prospective clinical evaluation of the effects of intraoperative systemic anticoagulation in patients undergoing arteriovenous fistula surgery Am Surg. 2010 Oct; 76(10):1112-4. . View in PubMed

Late outcomes of endovascular and open revascularization for nonatherosclerotic renal artery disease Arch Surg. 2010 Sep; 145(9):832-9. . View in PubMed

Racial and ethnic differences in patterns of treatment for acute peripheral arterial disease in the United States, 1998-2006 J Vasc Surg. 2010 Apr; 51(4 Suppl):21S-26S. . View in PubMed

Efficacy and safety of alfimeprase in patients with acute peripheral arterial occlusion (PAO) J Vasc Surg. 2010 Mar; 51(3):600-9. . View in PubMed

Premature carotid artery disease in pediatric cancer survivors treated with neck irradiation Pediatr Blood Cancer. 2009 Oct; 53(4):615-21. . View in PubMed

Primary stenting of the superficial femoral and popliteal artery J Vasc Surg. 2009 Sep; 50(3):542-7. . View in PubMed

Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression Cancer Res. 2009 May 01; 69(9):3736-45. . View in PubMed

Endovascular management of hoarseness due to a thoracic aneurysm: case report and review of the literature Vasc Endovascular Surg. 2009 Apr-May; 43(2):195-8. . View in PubMed

Patterns of treatment for peripheral arterial disease in the United States: 1996-2005 J Vasc Surg. 2009 Apr; 49(4):910-7. . View in PubMed

Repair of a high-flow iliac arteriovenous fistula using a thoracic endograft J Vasc Surg. 2009 Mar; 49(3):767-70. . View in PubMed

Acute arterial occlusion secondary to trauma Semin Vasc Surg. 2009 Mar; 22(1):25-8. . View in PubMed

An ultrasonic navigation system for endovascular aortic repair Stud Health Technol Inform. 2009; 142:218-20. . View in PubMed

Endovascular management of mycotic aortic aneurysms and associated aortoaerodigestive fistulas Ann Vasc Surg. 2009 Jan-Feb; 23(1):81-9. . View in PubMed

Assessing the performance of surgical teams Health Care Manage Rev. 2009 Jan-Mar; 34(1):29-41. . View in PubMed

Clinical use of topical thrombin as a surgical hemostat Biologics. 2008 Dec; 2(4):593-9. . View in PubMed

Heparin-platelet factor 4 antibodies are frequent after vascular surgery but are not a frequent cause of graft thrombosis or thrombocytopenia J Vasc Surg. 2008 Aug; 48(2):377-81. . View in PubMed

A comparison of recombinant thrombin to bovine thrombin as a hemostatic ancillary in patients undergoing peripheral arterial bypass and arteriovenous graft procedures J Vasc Surg. 2008 Jun; 47(6):1266-73. . View in PubMed

Internal jugular, subclavian, and axillary deep venous thrombosis and the risk of pulmonary embolism Vascular. 2008 Mar-Apr; 16(2):73-9. . View in PubMed

Nicardipine after aortic valve replacement and coronary artery bypass graft: case study Crit Care Clin. 2007 Oct; 23 Suppl 1:39-43. . View in PubMed

Race independently impacts outcome of infrapopliteal bypass for symptomatic arterial insufficiency Vasc Endovascular Surg. 2007 Oct-Nov; 41(5):397-401. . View in PubMed

Change in practice patterns of an academic division of vascular surgery Arch Surg. 2007 Aug; 142(8):733-6; discussion 736-7. . View in PubMed

A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis J Am Coll Surg. 2007 Aug; 205(2):256-65. . View in PubMed

Premature carotid artery disease in long-term survivors of childhood cancer treated with neck irradiation: a series of 5 cases J Pediatr Hematol Oncol. 2007 Jul; 29(7):480-4. . View in PubMed

Recanalization of a thrombosed carotid artery following endarterectomy Ann Vasc Surg. 2007 Mar; 21(2):172-7. . View in PubMed

Carbon dioxide digital subtraction angiography-assisted endovascular aortic aneurysm repair in the azotemic patient J Vasc Surg. 2007 Mar; 45(3):451-8; discussion 458-60. . View in PubMed

Preliminary retrograde visceral artery reconstruction for thoracoabdominal aortic aneurysms Ann Vasc Surg. 2007 Mar; 21(2):123-8. . View in PubMed

Current trends in the management of iatrogenic cervical carotid artery injuries Vasc Endovascular Surg. 2006 Oct-Nov; 40(5):354-61. . View in PubMed

Receptor tyrosine kinase EphB4 is a survival factor in breast cancer Am J Pathol. 2006 Jul; 169(1):279-93. . View in PubMed

Current guidelines produce competent endovascular surgeons J Vasc Surg. 2006 May; 43(5):992-8; discussion 998. . View in PubMed

A phase I trial of alfimeprase for peripheral arterial thrombolysis J Vasc Interv Radiol. 2005 Aug; 16(8):1075-83. . View in PubMed

Influence of transmetatarsal amputation in patients requiring lower extremity distal revascularization Am Surg. 2004 Oct; 70(10):845-9. . View in PubMed

Endovascular management of vascular disease: current technology and applications Surg Clin North Am. 2004 Oct; 84(5):xi-xii. . View in PubMed

Current endovascular management of atherosclerotic renal artery stenosis Surg Clin North Am. 2004 Oct; 84(5):1353-64, vii-viii. . View in PubMed

Basilic vein transposition fistula: a good option for maintaining hemodialysis access site options? J Vasc Surg. 2004 May; 39(5):1043-7.. View in PubMed

Renal revascularization in Takayasu arteritis-induced renal artery stenosis J Vasc Surg. 2004 Apr; 39(4):749-57. . View in PubMed

Management of an abdominal aortic aneurysm in a patient with end-stage liver disease Am J Transplant. 2004 Apr; 4(4):666-8. . View in PubMed

Endovascular management of iliac vein occlusive disease Ann Vasc Surg. 2004 Mar; 18(2):228-33. . View in PubMed

Rupture of a previously thrombosed thoracoabdominal aneurysm Ann Vasc Surg. 2003 Mar; 17(2):143-7. . View in PubMed

Hypoplasia of the descending thoracic and abdominal aorta: a report of two cases and review of the literature J Vasc Surg. 2002 Oct; 36(4):844-8. . View in PubMed

Anticoagulation is an effective treatment for aortic mural thrombi J Vasc Surg. 2002 Oct; 36(4):713-9. . View in PubMed

Concomitant vascular procedures for malignancies with vascular invasion Arch Surg. 2002 Aug; 137(8):901-6; discussion 906-7. . View in PubMed

Clinical importance of the "seat belt sign" in blunt trauma to the neck Am Surg. 2002 May; 68(5):441-5. . View in PubMed

Gelatin-thrombin-based hemostatic sealant for intraoperative bleeding in vascular surgery Ann Vasc Surg. 2002 May; 16(3):286-93. . View in PubMed

Injury induced neointima formation and its inhibition by retrovirus-mediated transfer of nitride oxide synthase gene in an in-vitro human saphenous vein culture model Atherosclerosis. 2002 Mar; 161(1):113-22. . View in PubMed

Initial experience with dorsal venous arch arterialization for limb salvage Ann Vasc Surg. 2002 Mar; 16(2):187-92. . View in PubMed

Ex vivo repair of a large renal artery aneurysm and associated arteriovenous fistula Ann Vasc Surg. 2002 Mar; 16(2):141-4. . View in PubMed

Does surgical intervention significantly prolong the patency of failed angioaccess grafts previously treated with percutaneous techniques? Ann Vasc Surg. 2002 Mar; 16(2):197-200.. View in PubMed

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