Gage Dekoeyer Crump, PhD

Professor of Stem Cell & Regenerative Medicine

Director, DSR PhD Program

Vice Chair, Department of Stem Cell Biology and Regenerative Medicine

Interim Chair of Stem Cell Biology and Regenerative Medicine

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Publications

  • Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways Biol Open. 2021 02 25; 10(2). . View in PubMed
  • Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer Proc Natl Acad Sci U S A. 2020 10 06; 117(40):24876-24884. . View in PubMed
  • Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms Dev Biol. 2018 02 01; 434(1):7-14. . View in PubMed
  • Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration Nat Genet. 2017 Sep; 49(9):1346-1353. . View in PubMed
  • Building and maintaining joints by exquisite local control of cell fate Wiley Interdiscip Rev Dev Biol. 2017 01; 6(1). . View in PubMed
  • Genome-wide analysis of facial skeletal regionalization in zebrafish Development. 2017 08 15; 144(16):2994-3005. . View in PubMed
  • Endoderm Jagged induces liver and pancreas duct lineage in zebrafish Nat Commun. 2017 10 03; 8(1):769. . View in PubMed
  • Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear Sci Rep. 2017 05 31; 7(1):2497. . View in PubMed
  • Competition between Jagged-Notch and Endothelin1 Signaling Selectively Restricts Cartilage Formation in the Zebrafish Upper Face PLoS Genet. 2016 Apr; 12(4):e1005967. . View in PubMed
  • Lessons on skeletal cell plasticity from studying jawbone regeneration in zebrafish Bonekey Rep. 2016; 5:853. . View in PubMed
  • Ihha induces hybrid cartilage-bone cells during zebrafish jawbone regeneration Development. 2016 06 15; 143(12):2066-76. . View in PubMed
  • Ancient origin of lubricated joints in bony vertebrates Elife. 2016 07 19; 5. . View in PubMed
  • Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State Dev Cell. 2015 Nov 09; 35(3):358-65. . View in PubMed
  • Dynamic epithelia of the developing vertebrate face Curr Opin Genet Dev. 2015 Jun; 32:66-72. . View in PubMed
  • Eph-Pak2a signaling regulates branching of the pharyngeal endoderm by inhibiting late-stage epithelial dynamics Development. 2015 Mar 15; 142(6):1089-94. . View in PubMed
  • Zebrafish Craniofacial Development: A Window into Early Patterning Curr Top Dev Biol. 2015; 115:235-69. . View in PubMed
  • Discrete Notch signaling requirements in the specification of hematopoietic stem cells EMBO J. 2014 Oct 16; 33(20):2363-73. . View in PubMed
  • Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a Development. 2014 Sep; 141(18):3583-93. . View in PubMed
  • Wnt-dependent epithelial transitions drive pharyngeal pouch formation Dev Cell. 2013 Feb 11; 24(3):296-309. . View in PubMed
  • Regenerative potential of the zebrafish corneal endothelium Exp Eye Res. 2013 Jan; 106:1-4. . View in PubMed
  • New perspectives on pharyngeal dorsoventral patterning in development and evolution of the vertebrate jaw Dev Biol. 2012 Nov 15; 371(2):121-35. . View in PubMed
  • An essential role of variant histone H33 for ectomesenchyme potential of the cranial neural crest. PLoS Genet. 2012 Sep; 8(9):e1002938. . View in PubMed
  • The LIM protein Ajuba restricts the second heart field progenitor pool by regulating Isl1 activity Dev Cell. 2012 Jul 17; 23(1):58-70. . View in PubMed
  • Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors Dev Biol. 2012 Feb 15; 362(2):230-41. . View in PubMed
  • Bmps and id2a act upstream of Twist1 to restrict ectomesenchyme potential of the cranial neural crest PLoS Genet. 2012; 8(5):e1002710. . View in PubMed
  • Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton Development. 2011 Dec; 138(23):5135-46. . View in PubMed
  • Gremlin 2 regulates distinct roles of BMP and Endothelin 1 signaling in dorsoventral patterning of the facial skeleton Development. 2011 Dec; 138(23):5147-56. . View in PubMed
  • Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo Development. 2011 Aug; 138(15):3113-23. . View in PubMed
  • Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions Development. 2010 Aug 01; 137(15):2527-37. . View in PubMed
  • Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face Development. 2010 Jun; 137(11):1843-52. . View in PubMed
  • The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity Development. 2008 Jun; 135(11):1935-46. . View in PubMed
  • Hierarchical assembly of presynaptic components in defined Celegans synapses. Nat Neurosci. 2006 Dec; 9(12):1488-98. . View in PubMed
  • Moz-dependent Hox expression controls segment-specific fate maps of skeletal precursors in the face Development. 2006 Jul; 133(14):2661-9. . View in PubMed
  • Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development Development. 2006 Mar; 133(6):1069-77. . View in PubMed
  • A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development Development. 2005 Mar; 132(5):1069-83. . View in PubMed
  • Mammalian SAD kinases are required for neuronal polarization Science. 2005 Feb 11; 307(5711):929-32. . View in PubMed
  • An essential role for Fgfs in endodermal pouch formation influences later craniofacial skeletal patterning Development. 2004 Nov; 131(22):5703-16. . View in PubMed
  • An integrin-dependent role of pouch endoderm in hyoid cartilage development PLoS Biol. 2004 Sep; 2(9):E244. . View in PubMed
  • Endothelin 1-mediated regulation of pharyngeal bone development in zebrafish Development. 2003 Apr; 130(7):1339-51. . View in PubMed
  • Polarized dendritic transport and the AP-1 mu1 clathrin adaptor UNC-101 localize odorant receptors to olfactory cilia Neuron. 2001 Aug 02; 31(2):277-87. . View in PubMed
  • The SAD-1 kinase regulates presynaptic vesicle clustering and axon termination Neuron. 2001 Jan; 29(1):115-29. . View in PubMed
  • The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in Celegans olfactory neurons. Neuron. 1998 Jan; 20(1):55-67. . View in PubMed
  • Olfactory recognition and discrimination in Caenorhabditis elegans Cold Spring Harb Symp Quant Biol. 1996; 61:157-64. . View in PubMed