Gary Ulaner, MD, PhD

Clinical Professor of Radiology and Cancer Biology (Part Time)

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Overview

Dr. Gary Ulaner is the James & Pamela Muzzy Endowed Chair of Molecular Imaging and Therapy (MIT) at the Hoag Family Cancer Institute and Professor of Radiology and Translational Genomics at the University of Southern California.

Gary has been the principal investigator of prospective clinical trials for six novel PET radiotracers for patients with breast cancer, prostate cancer and myeloma, funded by two National Institutes of Health R01s, as well as grants from the Department of Defense (DoD) Breast Cancer Research Programs, Susan G. Komen Foundation, and Rising Tide Foundation. His clinical trials emphasize targeted imaging to guide targeted therapy of cancer, particularly ER, HER2, PSMA and CD38 targeted PET imaging.

Gary in on the editorial board of 4 leading radiology journals, authored the text “Fundamentals of Oncologic PET/CT”, and is on the scientific advisory boards of ImaginAb, GE Healthcare, and the Lobular Breast Cancer Alliance.

Gary currently lives in Irvine, California, with his wife, Alena, son, Ilya, and daughter, Anabel. He met his wife swing dancing, and they are still dancing today, albeit with less frequency.

Awards

  • National Institutes of Health Cancer Biology Pre-Doctoral Fellowship, 1994
  • National Institutes of Health Medical Scientist Training Program, 1997
  • National Institutes of Health Post-Doctoral Fellowship, 2001
  • RSNA Roentgen Resident Research Award, 2005
  • Resident of the Year, University of Southern California, 2009
  • RSNA Excellence Award for Research, 2011
  • Susan Komen for the Cure Career Catalyst Award, 2012
  • Department of Defense Breakthrough Award, 2014
  • Radiographics Educational Design Award, 2015
  • Radiology Editor’s Recognition Award with Special Distinction, 2015
  • Radiology Editor’s Recognition Award with Special Distinction, 2016
  • Jon Shevell Young Scientist Scholarship, Susan Komen Foundation, 2016
  • SNMMI Best Breast Cancer Research Abstract, 2016
  • SNMMI first place prize in Basic Science, 2016
  • MSKCC Department of Radiology, Excellence in Teaching Award, 2016
  • Weill Cornell Department of Radiology, Best Teacher, 2016
  • Jon Shevell Award from the Susan Komen Foundation, 2017
  • Clinical Nuclear Medicine Editor’s Award, 2017
  • Elected Fellow, American College of Nuclear Medicine, 2017
  • First Hal O’Brien Rising Star Award, Society of Nuclear Medicine and Molecular Imaging (SNMMI), 2018
  • American College of Nuclear Medicine – President’s Award, 2019
  • James and Pamela Muzzy Endowed Chair, 2021

Education and Training

  • Rutgers University, New Brunswick, NJ — BA — 05/1993 — Biology
  • Stanford University School of Medicine, Stanford, CA — MD, PhD — 06/2000 — Cancer Biology
  • Johns Hopkins , Baltimore, MD — 06/2001 — Internship
  • University of Southern California, Los Angeles, CA — 06/2009 — Diagnostic Radiology
  • University of Southern California, Los Angeles, CA — 06/2009 — Nuclear Medicine

Research Funding

  • Molecular Pathogenesis and Therapy of Systemic Histiocytic Neoplasms
    NIH · R37CA259260 · Apr 1, 2021 – Mar 31, 2026 · Role: Co-Investigator
  • Improved staging of lobular breast cancer with novel amino acid metabolic and tumor neovasculature receptor imaging.
    NIH · R21CA256280 · Dec 9, 2020 – Nov 30, 2022 · Role: Co-Investigator
  • CD38-targeted immunoPET of myeloma: Phase 2 trial of clinical applications
    NIH · R01CA248398 · Jul 1, 2020 – Jan 31, 2024 · Role: Principal Investigator
  • The Clinical PET Imaging of Metastatic Breast Cancer with Site-Specifically Labeled 89Zr-Trastuzumab
    NIH · R01CA204167 · Apr 1, 2016 – Mar 31, 2021 · Role: Co-Investigator

Research Keywords

  • Molecular Imaging and Therapy
  • PET/CT
  • Estrogen Receptor-targeted imaging
  • PSMA-targeted imaging and therapy
  • HER2-targeted imaging
  • CD38-targeted imaging
  • Translational Genomics

Publications

  • CD8 PET imaging with [89Zr]Zr-berdoxam-crefmirlimab in patients with solid tumors: the Phase II iCorrelate study. J Immunother Cancer. 2026 Mar 27; 14(3).. View in PubMed
  • ACR Appropriateness Criteria® Staging and Follow-Up of Adrenal Cancer. J Am Coll Radiol. 2026 Aug; 23(8):1675-1686.. View in PubMed
  • Targeted immunoPET imaging of multiple myeloma. Semin Hematol. 2025 Oct; 62(5):400-408.. View in PubMed
  • ACR Appropriateness Criteria® Breast Implant Evaluation: Update 2025. J Am Coll Radiol. 2026 Apr; 23(4):658-680.. View in PubMed
  • 61Cu-NODAGA Prostate-specific Membrane Antigen Imaging and Therapy for Prostate Cancer: Phase 1 Trial of a New Class of 61Cu-labeled PET Radiotracers. Radiology. 2025 12; 317(3):e251151.. View in PubMed
  • ACR Appropriateness Criteria® Female Breast Cancer Screening: 2025 Update. J Am Coll Radiol. 2025 Nov; 22(11S):S508-S530.. View in PubMed
  • RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition. Cancer Cell. 2026 Jan 12; 44(1):203-220.e8.. View in PubMed
  • The Van Nuys DCIS Prognostic Index →The Silverstein DCIS Prognostic Index. Ann Surg Oncol. 2025 Dec; 32(13):9475-9477.. View in PubMed
  • Enhanced contrast in FAP-targeting PET imaging with 61Cu-labeled FAP inhibitors: development and preclinical evaluation of novel [61Cu]Cu-Kalios PET radioligands. EJNMMI Radiopharm Chem. 2025 Aug 21; 10(1):55.. View in PubMed
  • Detection of Oligometastatic Disease in Breast Cancer: It’s the Little Things That Count. Radiology. 2025 Aug; 316(2):e251797.. View in PubMed