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Gianni Carraro

Assistant Professor of Research Surgery

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Email [email protected]
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Publications

  • A Chimeric Airway Model Enables Evaluation of Essential Genes In Vivo. Am J Respir Cell Mol Biol. 2026 Jun 16.. View in PubMed
  • Hypothyroidism impairs skeletal muscle regeneration after injury by altering myogenic and nonmyogenic pathways. JCI Insight. 2026 Mar 23; 11(6).. View in PubMed
  • Physical Fitness and Physical Function in Patients With Fabry Disease: A Cross-Sectional Multicentre Study. J Cachexia Sarcopenia Muscle. 2026 Feb; 17(1):e70233.. View in PubMed
  • Dapagliflozin in Patients With CKD With Fabry Disease. Kidney Int Rep. 2026 Mar; 11(3):103742.. View in PubMed
  • Human bronchial basal cells are a community of variants. iScience. 2025 Oct 17; 28(10):113633.. View in PubMed
  • Screening for Fabry disease in patients on kidney replacement therapy at Padua University Hospital Nephrology Unit. J Nephrol. 2025 Sep; 38(7):2013-2015.. View in PubMed
  • Physical performance and nutritional status in patients with Fabry disease: study design of an Italian multicenter cross-sectional study. J Nephrol. 2025 Jul; 38(6):1699-1701.. View in PubMed
  • Factor 3 regulates airway engraftment by human bronchial basal cells. Stem Cells Transl Med. 2025 Jan 17; 14(1).. View in PubMed
  • Oxidative stress and its role in Fabry disease. J Nephrol. 2024 06; 37(5):1201-1207.. View in PubMed
  • Tolvaptan Treatment and Long-Term Impact on Quality of Life in Autosomal Dominant Polycystic Kidney Disease Patients: A Pilot Study. Clin Drug Investig. 2024 Apr; 44(4):289-291.. View in PubMed
  • Increased Soluble Interleukin 6 Receptors in Fabry Disease. J Clin Med. 2023 Dec 29; 13(1).. View in PubMed
  • Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection. Nat Commun. 2023 09 19; 14(1):5814.. View in PubMed
  • Cryobanking of Human Distal Lung Epithelial Cells for Preservation of Their Phenotypic and Functional Characteristics. Am J Respir Cell Mol Biol. 2022 12; 67(6):623-631.. View in PubMed
  • FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells. Cell Mol Life Sci. 2022 Nov 29; 79(12):609.. View in PubMed
  • Insights gained in the pathology of lung disease through single-cell transcriptomics. J Pathol. 2022 07; 257(4):494-500.. View in PubMed
  • Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice. Cell Mol Life Sci. 2022 May 19; 79(6):302.. View in PubMed
  • Cell-Surface Programmed Death Ligand-1 Expression Identifies a Sub-Population of Distal Epithelial Cells Enriched in Idiopathic Pulmonary Fibrosis. Cells. 2022 05 10; 11(10).. View in PubMed
  • Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy. Eur Respir J. 2021 10; 58(5).. View in PubMed
  • Repeated injury promotes tracheobronchial tissue stem cell attrition. Stem Cells Transl Med. 2021 12; 10(12):1696-1713.. View in PubMed
  • Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI Insight. 2021 06 08; 6(11).. View in PubMed
  • Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia. Am J Respir Crit Care Med. 2021 05 15; 203(10):1275-1289.. View in PubMed
  • Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition. Nat Med. 2021 05; 27(5):806-814.. View in PubMed
  • Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 03 15; 203(6):707-717.. View in PubMed
  • Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs. Am J Respir Crit Care Med. 2020 12 01; 202(11):1540-1550.. View in PubMed
  • Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2021 01 07; 28(1):79-95.e8.. View in PubMed
  • Multilineage murine stem cells generate complex organoids to model distal lung development and disease. EMBO J. 2020 11 02; 39(21):e103476.. View in PubMed
  • Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells. iScience. 2020 May 22; 23(5):101083.. View in PubMed
  • Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia. Cells. 2020 04 02; 9(4).. View in PubMed
  • A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Mol Life Sci. 2019 Jul; 76(14):2817-2832.. View in PubMed
  • A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis. Front Genet. 2018; 9:746.. View in PubMed
  • Oxidative stress and the altered reaction to it in Fabry disease: A possible target for cardiovascular-renal remodeling? PLoS One. 2018; 13(9):e0204618. Ravarotto V, Carraro G , Pagnin E, Bertoldi G, . View in PubMed
  • In vitro Explant Cultures to Interrogate Signaling Pathways that Regulate Mouse Lung Development. Bio Protoc. 2018 May 20; 8(10):e2852.. View in PubMed
  • miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma. Am J Physiol Lung Cell Mol Physiol. 2018 08 01; 315(2):L328-L333.. View in PubMed
  • Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium. Stem Cell Reports. 2018 05 08; 10(5):1579-1595.. View in PubMed
  • Active epithelial Hippo signaling in idiopathic pulmonary fibrosis. JCI Insight. 2018 03 22; 3(6).. View in PubMed
  • Detection, Labeling, and Culture of Lung Stem and Progenitor Cells. Methods Mol Biol. 2018; 1842:167-181.. View in PubMed
  • Sin3a regulates epithelial progenitor cell fate during lung development. Development. 2017 07 15; 144(14):2618-2628.. View in PubMed
  • Roles for Myoepithelial Cells in the Formation and Maintenance of Submucosal Glands. Am J Respir Cell Mol Biol. 2017 06; 56(6):685-686.. View in PubMed
  • MicroRNA-142 is a multifaceted regulator in organogenesis, homeostasis, and disease. Dev Dyn. 2017 04; 246(4):285-290.. View in PubMed
  • Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia. J Pathol. 2017 Jan; 241(1):91-103.. View in PubMed
  • Generation and Validation of miR-142 Knock Out Mice. PLoS One. 2015; 10(9):e0136913.. View in PubMed
  • High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX. Cell Res. 2015 Jul; 25(7):837-50.. View in PubMed
  • A new notch for lung stem cells. Cell Stem Cell. 2015 Feb 05; 16(2):107-9.. View in PubMed
  • Hmga2 is required for canonical WNT signaling during lung development. BMC Biol. 2014 Mar 24; 12:21.. View in PubMed
  • miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development. Development. 2014 Mar; 141(6):1272-81.. View in PubMed
  • Fgf10-positive cells represent a progenitor cell population during lung development and postnatally. Development. 2014 Jan; 141(2):296-306.. View in PubMed
  • Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling. J Proteome Res. 2013 Dec 06; 12(12):5598-608.. View in PubMed
  • Transient Inhibition of FGFR2b-ligands signaling leads to irreversible loss of cellular β-catenin organization and signaling in AER during mouse limb development. PLoS One. 2013; 8(10):e76248.. View in PubMed
  • Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs. Mol Cell. 2013 Sep 26; 51(6):707-22.. View in PubMed
  • Amniotic fluid stem cells inhibit the progression of bleomycin-induced pulmonary fibrosis via CCL2 modulation in bronchoalveolar lavage. PLoS One. 2013; 8(8):e71679.. View in PubMed
  • Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype. J Clin Invest. 2012 Nov; 122(11):3862-72.. View in PubMed
  • Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development. PLoS One. 2012; 7(6):e38452.. View in PubMed
  • Cell-based therapies for lung disease. Br Med Bull. 2012; 101:147-61.. View in PubMed
  • The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1212-21.. View in PubMed
  • Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty. Cancer Biol Ther. 2011 Jan 01; 11(1):122-4.. View in PubMed
  • Mouse embryonic lung culture, a system to evaluate the molecular mechanisms of branching. J Vis Exp. 2010 Jun 30.. View in PubMed
  • Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One. 2010 Feb 24; 5(2):e9357.. View in PubMed
  • Lung organogenesis. Curr Top Dev Biol. 2010; 90:73-158.. View in PubMed
  • Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. Pediatr Res. 2009 Oct; 66(4):386-90.. View in PubMed
  • Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. Am J Respir Crit Care Med. 2009 Oct 15; 180(8):701-12.. View in PubMed
  • miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15; 333(2):238-50.. View in PubMed
  • Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells. 2008 Nov; 26(11):2902-11.. View in PubMed
  • Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS One. 2008 Jan 30; 3(1):e1516.. View in PubMed
  • Renal differentiation of amniotic fluid stem cells. Cell Prolif. 2007 Dec; 40(6):936-48.. View in PubMed
  • Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol. 2006 Nov 01; 299(1):52-62.. View in PubMed
  • In vitro culture on Matrigel favors the long-term maintenance of rat zona glomerulosa-cell differentiated phenotype. Int J Mol Med. 2006 Jun; 17(6):1101-10.. View in PubMed
  • Endothelin-1 and adrenomedullin enhance the growth of human adrenocortical carcinoma-derived SW-13 cell line by stimulating proliferation and inhibiting apoptosis. Int J Mol Med. 2005 Mar; 15(3):469-74.. View in PubMed
  • Ghrelin inhibits FGF-2-mediated angiogenesis in vitro and in vivo. Peptides. 2004 Dec; 25(12):2179-85.. View in PubMed
  • Human skin keratinocytes and fibroblasts express adrenomedullin and its receptors, and adrenomedullin enhances their growth in vitro by stimulating proliferation and inhibiting apoptosis. Int J Mol Med. 2003 May; 11(5):635-9.. View in PubMed
  • Adrenomedullin is expressed in cord blood hematopoietic cells and stimulates their clonal growth. Int J Mol Med. 2003 Feb; 11(2):157-60.. View in PubMed
  • Influence of the Alu-repeat I/D polymorphism in t-PA gene intron 8 on the stimulated t-PA release after venous occlusion. Clin Appl Thromb Hemost. 2003 Jan; 9(1):63-9.. View in PubMed
  • Differential expression of adrenomedullin and its receptors in newborn and adult rat thymus. Int J Mol Med. 2002 Dec; 10(6):767-71.. View in PubMed
  • Evidence for an autocrine-paracrine role of adrenomedullin in the cultured rat adrenal zona glomerulosa cells. Int J Mol Med. 2002 Oct; 10(4):401-5.. View in PubMed
  • Attempt to improve the diagnosis of immune thrombocytopenia by combined use of two different platelet autoantibodies assays (PAIgG and MACE). Haematologica. 2002 Oct; 87(10):1046-52.. View in PubMed
  • Prothrombin and the prothrombin 20210 G to A polymorphism: their relationship with hypercoagulability and thrombosis. Blood Rev. 1999 Dec; 13(4):205-10.. View in PubMed

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