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Giorgia Quadrato

Associate Professor of Stem Cell Biology and Regenerative Medicine

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Email [email protected]
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Overview

Dr. Quadrato’s laboratory focuses on understanding the cellular and molecular basis of human brain development and disease. By combining the use of emerging models of the human brain with single cell omics approaches, the laboratory is aiming to identify cell type specific disease mechanisms, and above all, new treatments for human neurodevelopmental disorders.

Publications

  • Microfluidic gradients create a stem cell model of the human central nervous system. Nat Protoc. 2026 Apr; 21(4):1263-1264.. View in PubMed
  • Developmental determinants of male bias in medulloblastoma. bioRxiv. 2026 Mar 25.. View in PubMed
  • ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron development. bioRxiv. 2026 Mar 18.. View in PubMed
  • Mapping human neurodevelopment-Brain organoids meet lineage tracing. FEBS Lett. 2025 Dec 16.. View in PubMed
  • Author Correction: Modelling human brain development and disease with organoids. Nat Rev Mol Cell Biol. 2025 Sep; 26(9):725.. View in PubMed
  • Conference Report: Cerebellar Development and Disease at Single-Cell Resolution. Cerebellum. 2025 Jun 05; 24(4):109.. View in PubMed
  • Publisher Correction: An integrated transcriptomic cell atlas of human neural organoids. Nature. 2025 Jan; 637(8045):E21.. View in PubMed
  • Modelling human brain development and disease with organoids. Nat Rev Mol Cell Biol. 2025 May; 26(5):389-412.. View in PubMed
  • Generation and long-term culture of human cerebellar organoids from pluripotent stem cells. Nat Protoc. 2025 06; 20(6):1584-1615.. View in PubMed
  • An integrated transcriptomic cell atlas of human neural organoids. Nature. 2024 11; 635(8039):690-698.. View in PubMed

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