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Hans I-Chen Harn, PhD

Assistant Professor Of Research Pathology

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Email [email protected]
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Overview

Hans Harn’s research focuses on mechanobiology, regenerative medicine, and wound healing. He has extensively studied tissue mechanics in skin development and regeneration, including wound-induced hair follicle neogenesis and the self-organization of skin organoids. His work has contributed to understanding the role of mechanical forces in tissue regeneration and the development of bioinspired strategies for wound healing.

Research Keywords

  • Regenerative Medicine
  • Mechanobiology
  • Skin Biology
  • Regenerative Wound Healing

Publications

  • Bioelectric state transitions enable de novo feather bud formation in developing skin. bioRxiv. 2026 Jun 29.. View in PubMed
  • Hypoxia and metabolic adaptation drive self-organization in organoid morphogenesis and tissue regeneration. Burns Trauma. 2026; 14:tkag038.. View in PubMed
  • Novel tissue mechanics-guided cellular flows drive the formation of feather follicles. EMBO J. 2026 Jun; 45(11):3926-3953.. View in PubMed
  • Epigenetic Coalitions Couple Tissue Growth to Generate Periodic Colour Patterns in Birds. bioRxiv. 2025 Dec 25.. View in PubMed
  • Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles. bioRxiv. 2025 Oct 01.. View in PubMed
  • Dominant dystrophic epidermolysis bullosa is associated with glycolytically active GATA3+ T helper 2 cells which may contribute to pruritus in lesional skin. Br J Dermatol. 2024 07 16; 191(2):252-260.. View in PubMed
  • Author Correction: Conserved regulatory switches for the transition from natal down to juvenile feather in birds. Nat Commun. 2024 Jun 25; 15(1):5367.. View in PubMed
  • Conserved regulatory switches for the transition from natal down to juvenile feather in birds. Nat Commun. 2024 May 16; 15(1):4174.. View in PubMed
  • Histone Trimethylations and HDAC5 Regulate Spheroid Subpopulation and Differentiation Signaling of Human Adipose-Derived Stem Cells. Stem Cells Transl Med. 2024 03 15; 13(3):293-308.. View in PubMed
  • Profibrotic Subsets of SPP1+ Macrophages and POSTN+ Fibroblasts Contribute to Fibrotic Scarring in Acne Keloidalis. J Invest Dermatol. 2024 Jul; 144(7):1491-1504.e10.. View in PubMed

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