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Hisashi Kanemaru

Assistant Professor of Research Surgery

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Email [email protected]
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Publications

  • Thymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy. Nat Commun. 2026 07 21; 17(1).. View in PubMed
  • Inflammaging in melanoma: Precision control for optimizing immune checkpoint inhibition. J Dermatol Sci. 2026 Jul 12.. View in PubMed
  • Divergent transcriptional states and kinetics of circulating tumor-infiltrating lymphocyte repertoires with highly homologous T-cell receptor sequences in a patient during immunotherapy. J Immunother Cancer. 2025 Jan 25; 13(1).. View in PubMed
  • Metastasis to hypopharynx from epidermotropic metastatic malignant melanoma. Drug Discov Ther. 2024 Jun 06; 18(2):140-142.. View in PubMed
  • Genetic intratumour heterogeneity and clonal evolution in extramammary Paget’s disease. Eur J Dermatol. 2024 Apr 01; 34(2):182-192.. View in PubMed
  • ANGPTL2-mediated epigenetic repression of MHC-I in tumor cells accelerates tumor immune evasion. Mol Oncol. 2023 12; 17(12):2637-2658.. View in PubMed
  • Clinical significance of circulating exosomal interleukin-23 and tumour necrosis factor-α messenger RNA in psoriasis. J Eur Acad Dermatol Venereol. 2023 06; 37(6):e815-e817.. View in PubMed
  • Elevation of cell-free DNA in patients with clinically amyopathic dermatomyositis. J Dermatol. 2023 06; 50(6):e189-e191.. View in PubMed
  • Future prospects for cancer immunotherapy using induced pluripotent stem cell-derived dendritic cells or macrophages. Exp Dermatol. 2023 03; 32(3):290-296.. View in PubMed
  • A Japanese case of melanoma of unknown origin with a rare BRAFV600R mutation was successfully treated with BRAF/MEK inhibitors. Drug Discov Ther. 2022 Nov 20; 16(5):256-257.. View in PubMed
  • Upregulated androgen receptor variant-7 mRNA and protein in extramammary Paget’s disease. J Eur Acad Dermatol Venereol. 2022 09; 36(9):e724-e726.. View in PubMed
  • Clinical significance of ERBB2 S310F mutation in extramammary Paget’s disease. J Dermatol. 2022 09; 49(9):e305-e306.. View in PubMed
  • Elevation of circulating interleukin-23 DNA levels in patients with psoriasis. J Dermatol. 2022 09; 49(9):e295-e296.. View in PubMed
  • Relationship between Type 2 diabetes mellitus and aggressiveness of melanoma. J Dermatol Sci. 2022 04; 106(1):65-67.. View in PubMed
  • Promising Blood-Based Biomarkers for Melanoma: Recent Progress of Liquid Biopsy and Its Future Perspectives. Curr Treat Options Oncol. 2022 04; 23(4):562-577.. View in PubMed
  • Genomic mutation analysis of circulating tumor DNA in metastatic cutaneous squamous cell carcinoma. J Dermatol Sci. 2022 04; 106(1):61-64.. View in PubMed
  • Intertumor and intratumor heterogeneity of PIK3CA mutations in extramammary Paget’s disease. J Dermatol. 2022 May; 49(5):508-514.. View in PubMed
  • Clinical significance of maximum standardized uptake value of positron emission tomography/computed tomography as prognostic factor in extramammary Paget’s disease. J Dermatol. 2022 06; 49(6):e201-e202.. View in PubMed
  • Analysis of microsatellite instability using Promega panel in dermatofibrosarcoma protuberans. Biosci Trends. 2022 May 17; 16(2):176-177.. View in PubMed
  • A protocol for quantifying lymphocyte-mediated cytotoxicity using an impedance-based real-time cell analyzer. STAR Protoc. 2022 03 18; 3(1):101128.. View in PubMed
  • Circulating phospholipase A2 group IV D DNA copies are elevated in psoriasis. J Eur Acad Dermatol Venereol. 2022 Apr; 36(4):e302-e304.. View in PubMed
  • Questionnaire Survey Regarding Troubles and Concerns Related to Clinical Research Based on the Clinical Trial Act for Clinicians and Academics. Kurume Med J. 2022 Mar 11; 67(1):17-21.. View in PubMed
  • Circulating Janus kinase family DNA levels in psoriasis: elevated JAK2 DNA copy number in cell-free DNA. J Dermatol. 2022 Mar; 49(3):e106-e107.. View in PubMed
  • Genomic landscape of circulating tumour DNA in metastatic extramammary Paget’s disease. Exp Dermatol. 2022 03; 31(3):341-348.. View in PubMed
  • A mechanism of cooling hot tumors: Lactate attenuates inflammation in dendritic cells. iScience. 2021 Sep 24; 24(9):103067.. View in PubMed
  • Clinical significance of skin colonization of Pseudomonas aeruginosa in cutaneous squamous cell carcinoma. J Dermatol. 2021 Dec; 48(12):e581-e582.. View in PubMed
  • Overexpression of Janus kinase 2 protein in extramammary Paget’s disease. Jpn J Clin Oncol. 2021 Jul 01; 51(7):1176-1178.. View in PubMed
  • Absence of microsatellite instability in extramammary Paget’s disease. Skin Health Dis. 2021 Sep; 1(3):e37.. View in PubMed
  • Liquid biopsy-based analysis by ddPCR and CAPP-Seq in melanoma patients. J Dermatol Sci. 2021 Jun; 102(3):158-166.. View in PubMed
  • Immune cell therapy against disseminated melanoma by utilizing induced pluripotent stem cell-derived myeloid cell lines producing interferon-beta or interleukin-15/interleukin-15 receptor alpha. J Dermatol Sci. 2021 May; 102(2):133-136.. View in PubMed
  • Immunotherapy with 4-1BBL-Expressing iPS Cell-Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma. Int J Mol Sci. 2021 Feb 16; 22(4).. View in PubMed
  • Nucleosome assembly protein 1-like 4, a new therapeutic target for proliferation and invasion of melanoma cells. J Dermatol Sci. 2021 Apr; 102(1):16-24.. View in PubMed
  • Existence of Staphylococcus aureus correlates with the progression of extramammary Paget’s disease: potential involvement of interleukin-17 and M2-like macrophage polarization. Eur J Dermatol. 2021 Feb 01; 31(1):48-54.. View in PubMed
  • Genomic mutational profiling of circulating tumour DNA in metastatic angiosarcoma. J Eur Acad Dermatol Venereol. 2021 Apr; 35(4):e293-e295.. View in PubMed
  • Skin microbiome in acral melanoma: Corynebacterium is associated with advanced melanoma. J Dermatol. 2021 Jan; 48(1):e15-e16.. View in PubMed
  • Serum levels of desmoglein-1 DNA copies in cell-free DNA of patients with pemphigus. J Dermatol. 2021 Jan; 48(1):e31-e32.. View in PubMed
  • Methyl-CpG binding domain protein 3: a new diagnostic marker and potential therapeutic target of melanoma. Biosci Trends. 2020 Nov 04; 14(5):390-395.. View in PubMed
  • Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma. J Dermatol Sci. 2020 Nov; 100(2):110-119.. View in PubMed
  • Retrospective study of COL1A1-PDGFB fusion gene-positive dermatofibrosarcoma protuberans in Kumamoto University. Clin Exp Dermatol. 2020 Dec; 45(8):1067-1068.. View in PubMed
  • Single administration of avelumab induced a complete response in thyroid transcription factor 1-positive combined Merkel cell carcinoma. J Dermatol. 2020 Nov; 47(11):1317-1321.. View in PubMed
  • BATF2 expression as a novel marker for invasive phenotype in malignant melanoma. J Dermatol. 2020 Oct; 47(10):e372-e373.. View in PubMed
  • Elevated circulating cell-free DNA levels in autoimmune bullous diseases. J Dermatol. 2020 Sep; 47(9):e345-e346.. View in PubMed
  • Circulating tumor necrosis factor-α DNA are elevated in psoriasis. J Dermatol. 2020 Sep; 47(9):1037-1040.. View in PubMed
  • Induced pluripotent stem cell-derived myeloid cells expressing OX40 ligand amplify antigen-specific T cells in advanced melanoma. Pigment Cell Melanoma Res. 2020 09; 33(5):744-755.. View in PubMed
  • Successful prednisolone treatment of peripartum Behçet disease associated with HLA-A26. Australas J Dermatol. 2020 Nov; 61(4):e441-e442.. View in PubMed
  • Serious disseminated intravascular coagulation associated with combination therapy of nivolumab and ipilimumab in advanced melanoma. J Dermatol. 2020 Jun; 47(6):e235-e237.. View in PubMed
  • Inhibition of Endoglin Exerts Antitumor Effects through the Regulation of Non-Smad TGF-β Signaling in Angiosarcoma. J Invest Dermatol. 2020 10; 140(10):2060-2072.e6.. View in PubMed
  • The Warburg effect and tumour immune microenvironment in extramammary Paget’s disease: overexpression of lactate dehydrogenase A correlates with immune resistance. J Eur Acad Dermatol Venereol. 2020 Aug; 34(8):1715-1721.. View in PubMed
  • Successful treatment of occult pancreatic melanoma using BRAF/MEK inhibitors. J Dermatol. 2020 Apr; 47(4):e126-e127.. View in PubMed
  • Case of cutaneous myoepithelioma managed with surgical resection without recurrence for 4 years. J Dermatol. 2019 Jun; 46(6):e206-e208.. View in PubMed
  • Brain abscess in an angiosarcoma patient during a disease-free interval. Drug Discov Ther. 2019; 13(3):175-176.. View in PubMed
  • The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception. iScience. 2018 Aug 31; 6:306-318.. View in PubMed
  • BATF2 activates DUSP2 gene expression and up-regulates NF-κB activity via phospho-STAT3 dephosphorylation. Int Immunol. 2018 05 24; 30(6):255-265.. View in PubMed
  • Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis. Int Immunol. 2018 03 08; 30(2):69-78.. View in PubMed
  • The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation. Eur J Dermatol. 2017 Oct 01; 27(5):464-471.. View in PubMed
  • Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):E7331-E7340.. View in PubMed
  • Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis. Cell Rep. 2017 06 27; 19(13):2730-2742.. View in PubMed
  • Achieved good response of S-1 and docetaxel combination chemotherapy in two patients with metastatic extramammary Paget’s disease. J Dermatol. 2017 May; 44(5):e103-e104.. View in PubMed
  • Small bowel perforation due to indistinguishable metastasis of angiosarcoma: case report and brief literature review. Surg Case Rep. 2016 Dec; 2(1):42.. View in PubMed
  • Investigation of FOXM1 as a Potential New Target for Melanoma. PLoS One. 2015; 10(12):e0144241.. View in PubMed
  • Combination chemotherapy with S-1 and docetaxel for cutaneous angiosarcoma resistant to paclitaxel. Drug Discov Ther. 2015 Feb; 9(1):75-7.. View in PubMed
  • Clinical significance of serum vascular endothelial-cadherin levels in inflammatory skin diseases. Ann Dermatol. 2014 Aug; 26(4):536-8.. View in PubMed
  • Platelet-rich plasma therapy is effective for the treatment of refractory skin ulcers in patients with systemic sclerosis. Mod Rheumatol. 2015 Jul; 25(4):660-1.. View in PubMed
  • A case of psoriasis accompanied by arthritis after delivery. Biosci Trends. 2014 Feb; 8(1):64-7.. View in PubMed
  • Case of neuro-Behçet’s disease successfully maintained a remission using infliximab for 2 years. J Dermatol. 2013 Aug; 40(8):632-4.. View in PubMed
  • The circulating microRNA-221 level in patients with malignant melanoma as a new tumor marker. J Dermatol Sci. 2011 Mar; 61(3):187-93.. View in PubMed
  • Circulating microRNA associated with TNF-α signaling pathway in patients with plaque psoriasis. J Dermatol Sci. 2011 Mar; 61(3):209-11.. View in PubMed

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