Keck School Faculty

Howard Neil Hodis, MD
Howard Neil Hodis, MD
Professor of Medicine;Harry J. Bauer and Dorothy Bauer Rawlins Professorship in Cardiology
Medicine
CSC 132 Health Sciences Campus Los Angeles
Dr. Hodis' clinical interests include lipid and atherosclerosis treatment and vascular screenings. His current research includes air pollution and atherosclerosis, characterization of the atherogenicity of cholesterol oxidation products, and development of non-invasive technologies for measuring atherosclerosis and vascular function, among others.

Dr. Hodis earned his medical degree Keck School of Medicine. He then went on to complete his internship and residency at LAC+USC Medical Center followed by an Edmondson Medical Research Fellowship.

North American Menopause Society: Ooops. Something went wrong., 2010

North American Menopause Society: Thomas Clarkson Outstanding Clinical and Basic Science Research Award, 2010

Association of American Physicians: Ooops. Something went wrong., 2008

Western Society for Clinical Investigation: Member, 2008

Association of American Physicians: Member, 2008

Western Society for Clinical Investigation: Ooops. Something went wrong., 2008

American Heart Association: Fellow, 1991

American Heart Association: Ooops. Something went wrong., 1991

Department of Family Medicine, USC: Outstanding Teacher Award, 1991

Department of Family Medicine, USC: Ooops. Something went wrong., 1991

: Phi Beta Kappa, 1979

: Ooops. Something went wrong., 1979

USC: Alpha Mu Gamma, 1976

USC: Outstanding Young Men of America Award, Phi Kappa Phi, 1976

USC: Ooops. Something went wrong., 1976

Differential Effect of Plasma Estradiol on Subclinical Atherosclerosis Progression in Early vs Late Postmenopause J Clin Endocrinol Metab. 2019 Feb 01; 104(2):293-300. . View in PubMed

Changes in carotid artery intima-media thickness 3 years after cessation of menopausal hormone therapy: follow-up from the Kronos Early Estrogen Prevention Study Menopause. 2019 Jan; 26(1):24-31. . View in PubMed

Apolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease Menopause. 2019 Jan; 26(1):7-15. . View in PubMed

Loss of CXCR4 on non-classical monocytes in participants of the Women's Interagency HIV Study (WIHS) with subclinical atherosclerosis Cardiovasc Res. 2018 Dec 05. . View in PubMed

Carotid artery atherosclerosis is associated with mortality in HIV-positive women and men AIDS. 2018 Oct 23; 32(16):2393-2403. . View in PubMed

Differential effect of plasma estradiol on subclinical atherosclerosis progression in early versus late postmenopause J Clin Endocrinol Metab. 2018 Sep 28. . View in PubMed

Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection J Infect Dis. 2018 Sep 22; 218(9):1474-1479. . View in PubMed

Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans Sci Rep. 2018 Sep 21; 8(1):14212. . View in PubMed

Carotid artery atherosclerosis is associated with mortality in hiv-positive women and men AIDS. 2018 Aug 09. . View in PubMed

Changes in carotid artery intima-media thickness 3 years after cessation of menopausal hormone therapy: follow-up from the Kronos Early Estrogen Prevention Study Menopause. 2018 Jul 16. . View in PubMed

Apolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease Menopause. 2018 Jul 02. . View in PubMed

Carotid Artery Stiffness and Cognitive Decline Among Women With or at Risk for HIV Infection J Acquir Immune Defic Syndr. 2018 Jul 01; 78(3):338-347. . View in PubMed

Gut Microbial-related Choline Metabolite Trimethylamine-N-oxide is Associated with Progression of Carotid Artery Atherosclerosis in HIV Infection J Infect Dis. 2018 Jun 15. . View in PubMed

Cardiovascular risk after withdrawal of hormone therapy Menopause. 2018 Apr; 25(4):365-367. . View in PubMed

Carotid Artery Stiffness And Cognitive Decline Among Women With Or At Risk For Hiv Infection J Acquir Immune Defic Syndr. 2018 Mar 23. . View in PubMed

Estradiol Therapy After Menopause Mitigates Effects of Stress on Cortisol and Working Memory J Clin Endocrinol Metab. 2017 Dec 01; 102(12):4457-4466. . View in PubMed

Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS) JAMA Intern Med. 2017 Oct 01; 177(10):1471-1479. . View in PubMed

Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis Mayo Clin Proc. 2017 Sep; 92(9):1328-1340. . View in PubMed

Association of Macrophage Inflammation Biomarkers With Progression of Subclinical Carotid Artery Atherosclerosis in HIV-Infected Women and Men J Infect Dis. 2017 May 01; 215(9):1352-1361. . View in PubMed

Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo: the Kronos Early Estrogen Prevention Study Menopause. 2017 Mar; 24(3):238-246. . View in PubMed

Carotid Artery Intima-Media Thickness and Subclinical Atherosclerosis in Women With Remote Histories of Preeclampsia: Results From a Rochester Epidemiology Project-Based Study and Meta-analysis Mayo Clin Proc. 2017 09; 92(9):1328-1340. . View in PubMed

Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo: the Kronos Early Estrogen Prevention Study Menopause. 2017 03; 24(3):238-246. . View in PubMed

Association of Macrophage Inflammation Biomarkers With Progression of Subclinical Carotid Artery Atherosclerosis in HIV-Infected Women and Men J Infect Dis. 2017 05 01; 215(9):1352-1361. . View in PubMed

Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS) JAMA Intern Med. 2017 10 01; 177(10):1471-1479. . View in PubMed

Estradiol Therapy After Menopause Mitigates Effects of Stress on Cortisol and Working Memory J Clin Endocrinol Metab. 2017 12 01; 102(12):4457-4466. . View in PubMed

Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS) PLoS One. 2017; 12(12):e0188725. . View in PubMed

Effect of Reproductive History and Exogenous Hormone Use on Cognitive Function in Mid- and Late Life J Am Geriatr Soc. 2016 Dec; 64(12):2448-2456. . View in PubMed

Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause Atherosclerosis. 2016 Nov; 254:282-290. . View in PubMed

Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis Neurology. 2016 Aug 16; 87(7):699-708. . View in PubMed

HIV Infection and Carotid Artery Intima-media Thickness: Pooled Analyses Across 5 Cohorts of the NHLBI HIV-CVD Collaborative Clin Infect Dis. 2016 Jul 15; 63(2):249-56. . View in PubMed

Impaired coronary artery distensibility is an endothelium-dependent process and is associated with vulnerable plaque composition Clin Physiol Funct Imaging. 2016 Jul; 36(4):261-8. . View in PubMed

Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype Neurobiol Aging. 2016 Apr; 40:155-163. . View in PubMed

Effect of Reproductive History and Exogenous Hormone Use on Cognitive Function in Mid- and Late Life J Am Geriatr Soc. 2016 12; 64(12):2448-2456. . View in PubMed

Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause Atherosclerosis. 2016 11; 254:282-290. . View in PubMed

Association of bilateral oophorectomy with cognitive function in healthy, postmenopausal womenFertil Steril. 2016 09 01; 106(3):749-756. e2. . View in PubMed

HIV Infection and Carotid Artery Intima-media Thickness: Pooled Analyses Across 5 Cohorts of the NHLBI HIV-CVD Collaborative Clin Infect Dis. 2016 07 15; 63(2):249-56. . View in PubMed

A prospective, randomized clinical trial of antiretroviral therapies on carotid wall thickness AIDS. 2015 Sep 10; 29(14):1775-83. . View in PubMed

Extended-Release Niacin Versus Fenofibrate in HIV-Infected Participants With Low High-Density Lipoprotein Cholesterol: Effects on Endothelial Function, Lipoproteins, and Inflammation Clin Infect Dis. 2015 Sep 01; 61(5):840-9. . View in PubMed

HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis Clin Infect Dis. 2015 Aug 15; 61(4):640-50. . View in PubMed

Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial JAMA. 2015 Aug 11; 314(6):570-81. . View in PubMed

Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study PLoS Med. 2015 Jun; 12(6):e1001833; discussion e1001833. . View in PubMed

Hormone therapy and risk of all-cause mortality in women treated with statins Menopause. 2015 Apr; 22(4):363-4. . View in PubMed

Abnormal blood rheology and chronic low grade inflammation: possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects Atherosclerosis. 2015 Mar; 239(1):248-51. . View in PubMed

Echolucency of the carotid artery intima-media complex and intima-media thickness have different cardiovascular risk factor relationships: the Women's Interagency HIV Study J Am Heart Assoc. 2015 Feb 19; 4(2). . View in PubMed

Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women J Clin Endocrinol Metab. 2015 Feb; 100(2):508-15. . View in PubMed

Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial Ann Intern Med. 2014 Aug 19; 161(4):249-60. . View in PubMed

Hormone replacement therapy and the association with coronary heart disease and overall mortality: clinical application of the timing hypothesis J Steroid Biochem Mol Biol. 2014 Jul; 142:68-75. . View in PubMed

Associations between urine excretion of isoflavonoids and cognition in postmenopausal women in the Women's Isoflavone Soy Health clinical trial J Am Geriatr Soc. 2014 Apr; 62(4):629-35. . View in PubMed

Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women Fertil Steril. 2014 Apr; 101(4):1117-22. . View in PubMed

Immunologic predictors of coronary artery calcium progression in a contemporary HIV cohort AIDS. 2014 Mar 27; 28(6):831-40. . View in PubMed

Menopausal hormone therapy and prevention of chronic diseases: IMS members react to the recent JAMA paper Climacteric. 2014 Feb; 17(1):99-101. . View in PubMed

Components of air pollution and cognitive function in middle-aged and older adults in Los Angeles Neurotoxicology. 2014 Jan; 40:1-7. . View in PubMed

Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. . View in PubMed

Blunted nocturnal cortisol rise is associated with higher carotid artery intima-media thickness (CIMT) in overweight African American and Latino youth Psychoneuroendocrinology. 2013 Sep; 38(9):1658-67. . View in PubMed

Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial Menopause. 2013 Aug; 20(8):840-4. . View in PubMed

Ectopic fat and adipokines in metabolically benign overweight/obese women: the Kronos Early Estrogen Prevention Study Obesity (Silver Spring). 2013 Aug; 21(8):1726-33. . View in PubMed

Birth weight and carotid artery intima-media thicknessJ Pediatr. 2013 May; 162(5):906-11. e1-2. . View in PubMed

Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS) J Clin Endocrinol Metab. 2013 Apr; 98(4):E610-8. . View in PubMed

Dysfunctional HDL and progression of atherosclerosis in HIV-1-infected and -uninfected adults Lipids Health Dis. 2013 Mar 05; 12:23. . View in PubMed

Genetic polymorphisms associated with carotid artery intima-media thickness and coronary artery calcification in women of the Kronos Early Estrogen Prevention Study Physiol Genomics. 2013 Jan 15; 45(2):79-88. . View in PubMed

Characterization of vascular disease risk in postmenopausal women and its association with cognitive performance PLoS One. 2013; 8(7):e68741. . View in PubMed

Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study Atherosclerosis. 2012 Dec; 225(2):408-11. . View in PubMed

Biomarkers of microbial translocation and macrophage activation: association with progression of subclinical atherosclerosis in HIV-1 infection J Infect Dis. 2012 Nov 15; 206(10):1558-67. . View in PubMed

Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults Stroke. 2012 Nov; 43(11):2865-70. . View in PubMed

Childhood air pollutant exposure and carotid artery intima-media thickness in young adults Circulation. 2012 Sep 25; 126(13):1614-20. . View in PubMed

Herpes simplex virus type 2 (HSV-2) as a coronary atherosclerosis risk factor in HIV-infected men: multicenter AIDS cohort study Atherosclerosis. 2012 Aug; 223(2):433-6. . View in PubMed

Cytomegalovirus immunoglobulin G antibody is associated with subclinical carotid artery disease among HIV-infected women J Infect Dis. 2012 Jun 15; 205(12):1788-96. . View in PubMed

Equol production changes over time in postmenopausal women J Nutr Biochem. 2012 Jun; 23(6):573-9. . View in PubMed

Associations between retinol-binding protein 4 and cardiometabolic risk factors and subclinical atherosclerosis in recently postmenopausal women: cross-sectional analyses from the KEEPS study Cardiovasc Diabetol. 2012 May 15; 11:52. . View in PubMed

Intra-thoracic fat, cardiometabolic risk factors, and subclinical cardiovascular disease in healthy, recently menopausal women screened for the Kronos Early Estrogen Prevention Study (KEEPS) Atherosclerosis. 2012 Mar; 221(1):198-205. . View in PubMed

Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk J Cardiovasc Transl Res. 2011 Dec; 4(6):811-22. . View in PubMed

Isoflavone soy protein supplementation and atherosclerosis progression in healthy postmenopausal women: a randomized controlled trial Stroke. 2011 Nov; 42(11):3168-75. . View in PubMed

Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization Menopause. 2011 Nov; 18(11):1172-7. . View in PubMed

Carotid artery intima-media thickness in college students: race/ethnicity matters Atherosclerosis. 2011 Aug; 217(2):441-6. . View in PubMed

A "window of opportunity:" the reduction of coronary heart disease and total mortality with menopausal therapies is age- and time-dependent Brain Res. 2011 Mar 16; 1379:244-52. . View in PubMed

Association between human immunodeficiency virus infection and stiffness of the common carotid artery Stroke. 2010 Oct; 41(10):2163-70. . View in PubMed

Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women Menopause. 2010 Jul; 17(4):785-90. . View in PubMed

Drug firm conflicting interestsIf only WHI was done well. BMJ. 2010 Feb 16; 340:c591. . View in PubMed

Ambient air pollution and the progression of atherosclerosis in adults PLoS One. 2010 Feb 08; 5(2):e9096. . View in PubMed

Coronary heart disease and menopause management: the swinging pendulum of HRT Atherosclerosis. 2009 Dec; 207(2):336-40. . View in PubMed

Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women J Clin Endocrinol Metab. 2009 Nov; 94(11):4136-43. . View in PubMed

Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study AIDS. 2009 Aug 24; 23(13):1781-4. . View in PubMed

High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial Stroke. 2009 Mar; 40(3):730-6. . View in PubMed

Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men AIDS. 2008 Aug 20; 22(13):1615-24. . View in PubMed

Can menopausal hormone therapy prevent coronary heart disease? Trends Endocrinol Metab. 2008 Aug; 19(6):206-12.. View in PubMed

Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society Menopause. 2008 Jul-Aug; 15(4 Pt 1):584-602. . View in PubMed

Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes Atherosclerosis. 2008 Jul; 199(1):207-14. . View in PubMed

Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families Atherosclerosis. 2008 May; 198(1):160-5. . View in PubMed

Assessing benefits and risks of hormone therapy in 2008: new evidence, especially with regard to the heart Cleve Clin J Med. 2008 May; 75 Suppl 4:S3-12. . View in PubMed

Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial) Am J Cardiol. 2008 Apr 15; 101(8):1131-3. . View in PubMed

In Perspective: Estrogen Therapy Proves to Safely and Effectively Reduce Total Mortality and Coronary Heart Disease in Recently Postmenopausal Women Menopause Manag. 2008 Mar; 17(2):27-32. . View in PubMed

Brachial artery vasoreactivity is associated with cross-sectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease Atherosclerosis. 2008 Feb; 196(2):674-81. . View in PubMed

Estrogen therapy and coronary-artery calcification N Engl J Med. 2007 Sep 20; 357(12):1252-3; author reply 1254. . View in PubMed

Carotid artery intima-media thickness after raloxifene treatment J Womens Health (Larchmt). 2007 Apr; 16(3):370-8. . View in PubMed

Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus Am J Cardiol. 2007 Apr 01; 99(7):956-60. . View in PubMed

17beta-Estradiol reverses shear-stress-mediated low density lipoprotein modifications Free Radic Biol Med. 2006 Aug 15; 41(4):568-78. . View in PubMed

Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes Diabetes Care. 2006 Jul; 29(7):1545-53. . View in PubMed

Long-term effect of estrogen replacement on plasma nitric oxide levels: results from the estrogen in the prevention of atherosclerosis trial (EPAT) Atherosclerosis. 2005 Aug; 181(2):375-80. . View in PubMed

Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial Menopause. 2005 Jul-Aug; 12(4):366-73. . View in PubMed

Carotid artery intima-media thickness and HIV infection: traditional risk factors overshadow impact of protease inhibitor exposure AIDS. 2005 Jun 10; 19(9):927-33. . View in PubMed

Effect of thiazolidinedione treatment on progression of subclinical atherosclerosis in premenopausal women at high risk for type 2 diabetes J Clin Endocrinol Metab. 2005 Apr; 90(4):1986-91. . View in PubMed

Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study Diabetes. 2005 Apr; 54(4):1228-32. . View in PubMed

A genome-wide scan for carotid artery intima-media thickness: the Mexican-American Coronary Artery Disease family study Stroke. 2005 Mar; 36(3):540-5. . View in PubMed

Ambient air pollution and atherosclerosis in Los Angeles Environ Health Perspect. 2005 Feb; 113(2):201-6. . View in PubMed

Association between monocyte Fcgamma subclass expression and acute coronary syndrome Immun Ageing. 2004 Nov 12; 1(1):4. . View in PubMed

Early onset of subclinical atherosclerosis in young persons with type 1 diabetes J Pediatr. 2004 Oct; 145(4):452-7. . View in PubMed

Elevated subclinical atherosclerosis associated with oophorectomy is related to time since menopause rather than type of menopause Fertil Steril. 2004 Aug; 82(2):391-7. . View in PubMed

Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women N Engl J Med. 2003 Aug 07; 349(6):535-45. . View in PubMed

Environmental tobacco smoke and carotid arterial stiffness Prev Med. 2003 Aug; 37(2):148-54. . View in PubMed

Does elevated body mass modify the influence of postmenopausal estrogen replacement on atherosclerosis progression: results from the estrogen in the prevention of atherosclerosis trial Atherosclerosis. 2003 May; 168(1):91-8. . View in PubMed

Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS) Circulation. 2002 Sep 17; 106(12):1453-9. . View in PubMed

Antiatherosclerosis interventions in women Am J Cardiol. 2002 Jul 03; 90(1A):17F-21F. . View in PubMed

Atherosclerosis imaging methods: assessing cardiovascular disease and evaluating the role of estrogen in the prevention of atherosclerosis Am J Cardiol. 2002 Jun 20; 89(12A):19E-27E; discussion 27E. . View in PubMed

Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent Arterioscler Thromb Vasc Biol. 2002 May 01; 22(5):843-8. . View in PubMed

Powered by SC CTSI
Go to Top