Keck School Faculty

Huizhong Tao

Huizhong Tao

Professor of Physiology and Neuroscience
ZNI 319, 1501 San Pablo Street Health Sciences Campus Los Angeles

Glutamatergic and GABAergic neurons in pontine central gray mediate opposing valence-specific behaviors through a global network Neuron. 2023 Feb 28. . View in PubMed

The combined impact of Type D personality and depression on cardiovascular events after acute myocardial infarction Psychol Med. 2023 03; 53(4):1379-1389. . View in PubMed

Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner Mol Med. 2023 02 06; 29(1):19. . View in PubMed

Impact of anesthetic strategy on outcomes for patients with acute basilar artery occlusion undergoing mechanical thrombectomy J Neurointerv Surg. 2022 Nov; 14(11):1073-1076. . View in PubMed

The Potential Mediating Effects of Inflammation on the Association Between Type D Personality and Coronary Plaque Vulnerability in Patients With Coronary Artery Disease: An Optical Coherence Tomography Study Psychosom Med. 2022 05 01; 84(4):468-477. . View in PubMed

Application of AAV1 for Anterograde Transsynaptic Circuit Mapping and Input-Dependent Neuronal Cataloging Curr Protoc. 2022 Jan; 2(1):e339. . View in PubMed

The Chinese Herbal Formula Huoxiang Zhengqi Dropping Pills Prevents Acute Intestinal Injury Induced by Heatstroke by Increasing the Expression of Claudin-3 in Rats Evid Based Complement Alternat Med. 2022; 2022:9230341. . View in PubMed

A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning Nat Commun. 2022 03 07; 13(1):1194. . View in PubMed

Cellular anatomy of the mouse primary motor cortex Nature. 2021 10; 598(7879):159-166. . View in PubMed

Medial preoptic area antagonistically mediates stress-induced anxiety and parental behavior Nat Neurosci. 2021 04; 24(4):516-528. . View in PubMed

Corticostriatal control of defense behavior in mice induced by auditory looming cues Nat Commun. 2021 02 15; 12(1):1040. . View in PubMed

Balanced Enhancements of Synaptic Excitation and Inhibition Underlie Developmental Maturation of Receptive Fields in the Mouse Visual Cortex J Neurosci. 2021 12 08; 41(49):10065-10079. . View in PubMed

Phasic Off responses of auditory cortex underlie perception of sound duration Cell Rep. 2021 04 20; 35(3):109003. . View in PubMed

Investigation of nitrogen pollutants transformation and its pathways along the long-distance prechlorinated raw water distribution system Chemosphere. 2020 Sep; 255:126833. . View in PubMed

Impact of type D personality on major adverse cardiac events in patients undergoing percutaneous coronary intervention: The mediating role of cognitive appraisal and coping style J Psychosom Res. 2020 09; 136:110192. . View in PubMed

Zona Incerta: An Integrative Node for Global Behavioral Modulation Trends Neurosci. 2020 02; 43(2):82-87. . View in PubMed

Luminescence Imaging of Acute Liver Injury by Biodegradable and Biocompatible Nanoprobes ACS Nano. 2020 09 22; 14(9):11083-11099. . View in PubMed

Contextual and cross-modality modulation of auditory cortical processing through pulvinar mediated suppression Elife. 2020 03 06; 9. . View in PubMed

A Differential Circuit via Retino-Colliculo-Pulvinar Pathway Enhances Feature Selectivity in Visual Cortex through Surround SuppressionNeuron. 2020 01 22; 105(2):355-369. e6. . View in PubMed

Revealing the changes of bacterial community from water source to consumers tap: A full-scale investigation in eastern city of China J Environ Sci (China). 2020 Jan; 87:331-340. . View in PubMed

Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry J Neurosci. 2020 04 15; 40(16):3250-3267. . View in PubMed

Cyclodextrin-Derived Intrinsically Bioactive Nanoparticles for Treatment of Acute and Chronic Inflammatory Diseases Adv Mater. 2019 Nov; 31(46):e1904607. . View in PubMed

A self-illuminating nanoparticle for inflammation imaging and cancer therapy Sci Adv. 2019 01; 5(1):eaat2953. . View in PubMed

Sparse Labeling and Neural Tracing in Brain Circuits by STARS Strategy: Revealing Morphological Development of Type II Spiral Ganglion Neurons Cereb Cortex. 2019 04 01; 29(4):1700. . View in PubMed

Sensory- and Motor-Related Responses of Layer 1 Neurons in the Mouse Visual Cortex J Neurosci. 2019 12 11; 39(50):10060-10070. . View in PubMed

Synaptic Mechanisms for Bandwidth Tuning in Awake Mouse Primary Auditory Cortex Cereb Cortex. 2019 07 05; 29(7):2998-3009. . View in PubMed

Selective Strengthening of Intracortical Excitatory Input Leads to Receptive Field Refinement during Auditory Cortical Development J Neurosci. 2019 02 13; 39(7):1195-1205. . View in PubMed

A cross-modality enhancement of defensive flight via parvalbumin neurons in zona incerta Elife. 2019 04 15; 8. . View in PubMed

Sparse Representation in Awake Auditory Cortex: Cell-type Dependence, Synaptic Mechanisms, Developmental Emergence, and Modulation Cereb Cortex. 2019 08 14; 29(9):3796-3812. . View in PubMed

A Broad-Spectrum ROS-Eliminating Material for Prevention of Inflammation and Drug-Induced Organ Toxicity Adv Sci (Weinh). 2018 Oct; 5(10):1800781. . View in PubMed

Multiscale and Multifunctional Emulsions by Host-Guest Interaction-Mediated Self-Assembly ACS Cent Sci. 2018 May 23; 4(5):600-605. . View in PubMed

Advanced emulsions via noncovalent interaction-mediated interfacial self-assembly Chem Commun (Camb). 2018 Mar 28; 54(25):3174-3177. . View in PubMed

Type D personality, but not Type A behavior pattern, is associated with coronary plaque vulnerability Psychol Health Med. 2018 Feb; 23(2):216-223. . View in PubMed

Prognostic Value of Type D Personality for In-stent Restenosis in Coronary Artery Disease Patients Treated With Drug-Eluting Stent Psychosom Med. 2018 01; 80(1):95-102. . View in PubMed

Inhibitory gain modulation of defense behaviors by zona incerta Nat Commun. 2018 03 20; 9(1):1151. . View in PubMed

A Targeting Nanotherapy for Abdominal Aortic Aneurysms J Am Coll Cardiol. 2018 11 27; 72(21):2591-2605. . View in PubMed

Sparse Labeling and Neural Tracing in Brain Circuits by STARS Strategy: Revealing Morphological Development of Type II Spiral Ganglion Neurons Cereb Cortex. 2018 07 06. . View in PubMed

Input-output organization of the mouse claustrum J Comp Neurol. 2018 10 15; 526(15):2428-2443. . View in PubMed

Spatial Asymmetry and Short-Term Suppression Underlie Direction Selectivity of Synaptic Excitation in the Mouse Visual Cortex Cereb Cortex. 2018 06 01; 28(6):2059-2070. . View in PubMed

A Non-canonical Reticular-Limbic Central Auditory Pathway via Medial Septum Contributes to Fear ConditioningNeuron. 2018 01 17; 97(2):406-417. e4. . View in PubMed

Transforming Sensory Cues into Aversive Emotion via Septal-Habenular PathwayNeuron. 2018 09 05; 99(5):1016-1028. e5. . View in PubMed

[Chemical agents modulating bacterial biofilm formation and development] Sheng Wu Gong Cheng Xue Bao. 2017 Sep 25; 33(9):1433-1465. . View in PubMed

[Progress in c-di-GMP inhibitors] Sheng Wu Gong Cheng Xue Bao. 2017 Sep 25; 33(9):1466-1477. . View in PubMed

Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility Circulation. 2017 May 02; 135(18):1733-1748. . View in PubMed

AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors Neuron. 2017 Jan 04; 93(1):33-47. . View in PubMed

Distinct Inhibitory Circuits Orchestrate Cortical beta and gamma Band OscillationsNeuron. 2017 12 20; 96(6):1403-1418. e6. . View in PubMed

Diversity in Excitation-Inhibition Mismatch Underlies Local Functional Heterogeneity in the Rat Auditory Cortex Cell Rep. 2017 04 18; 19(3):521-531. . View in PubMed

Direction selectivity starts early Nat Neurosci. 2017 06 27; 20(7):899-901. . View in PubMed

Prediction of Bronchial Mucus Plugs Formation in Patients with Refractory Mycoplasma Pneumoniae Pneumonia J Trop Pediatr. 2017 04 01; 63(2):148-154. . View in PubMed

Dcc Mediates Functional Assembly of Peripheral Auditory Circuits Sci Rep. 2016 Apr 04; 6:23799. . View in PubMed

EphA7 regulates spiral ganglion innervation of cochlear hair cells Dev Neurobiol. 2016 Apr; 76(4):452-69. . View in PubMed

Cross-Modality Sharpening of Visual Cortical Processing through Layer-1-Mediated Inhibition and Disinhibition Neuron. 2016 Mar 02; 89(5):1031-45. . View in PubMed

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis Biomaterials. 2016 10; 105:167-184. . View in PubMed

A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease Biomaterials. 2016 10; 105:206-221. . View in PubMed

Thalamocortical Innervation Pattern in Mouse Auditory and Visual Cortex: Laminar and Cell-Type Specificity Cereb Cortex. 2016 06; 26(6):2612-25. . View in PubMed

Strengthening of Direction Selectivity by Broadly Tuned and Spatiotemporally Slightly Offset Inhibition in Mouse Visual Cortex Cereb Cortex. 2015 Sep; 25(9):2466-77. . View in PubMed

BMP7-Based Functionalized Self-Assembling Peptides for Nucleus Pulposus Tissue Engineering ACS Appl Mater Interfaces. 2015 Aug 12; 7(31):17076-87. . View in PubMed

Synaptic Basis for Differential Orientation Selectivity between Complex and Simple Cells in Mouse Visual Cortex J Neurosci. 2015 Aug 05; 35(31):11081-93. . View in PubMed

Differential Receptive Field Properties of Parvalbumin and Somatostatin Inhibitory Neurons in Mouse Auditory Cortex Cereb Cortex. 2015 Jul; 25(7):1782-91. . View in PubMed

Auditory cortex controls sound-driven innate defense behaviour through corticofugal projections to inferior colliculus Nat Commun. 2015 Jun 11; 6:7224. . View in PubMed

Sensory Cortical Control of a Visually Induced Arrest Behavior via Corticotectal Projections Neuron. 2015 May 06; 86(3):755-67. . View in PubMed

Ocular dominance plasticity disrupts binocular inhibition-excitation matching in visual cortex Curr Biol. 2015 Mar 16; 25(6):713-721. . View in PubMed

Synaptic mechanisms for generating temporal diversity of auditory representation in the dorsal cochlear nucleus J Neurophysiol. 2015 Mar 01; 113(5):1358-68. . View in PubMed

Functional response properties of VIP-expressing inhibitory neurons in mouse visual and auditory cortex Front Neural Circuits. 2015; 9:22. . View in PubMed

A feedforward inhibitory circuit mediates lateral refinement of sensory representation in upper layer 2/3 of mouse primary auditory cortex J Neurosci. 2014 Oct 08; 34(41):13670-83. . View in PubMed

Formation of excitation-inhibition balance: inhibition listens and changes its tune Trends Neurosci. 2014 Oct; 37(10):528-30. . View in PubMed

Scaling down of balanced excitation and inhibition by active behavioral states in auditory cortex Nat Neurosci. 2014 Jun; 17(6):841-50. . View in PubMed

The significance of YKL-40 protein in liver fibrosis Inflamm Res. 2014 Apr; 63(4):249-54. . View in PubMed

Monocular Deprivation in Mice Bio Protoc. 2014 Jan 20; 4(2). . View in PubMed

Thresholding of auditory cortical representation by background noise Front Neural Circuits. 2014; 8:133. . View in PubMed

Intracortical multiplication of thalamocortical signals in mouse auditory cortex Nat Neurosci. 2013 Sep; 16(9):1179-81. . View in PubMed

Linear transformation of thalamocortical input by intracortical excitation Nat Neurosci. 2013 Sep; 16(9):1324-30. . View in PubMed

Interaural level difference-dependent gain control and synaptic scaling underlying binaural computation Neuron. 2013 Aug 21; 79(4):738-53. . View in PubMed

Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation J Neurosci. 2013 Jul 24; 33(30):12242-54. . View in PubMed

The role of methyl-CpG binding protein 2 in liver fibrosis Toxicology. 2013 Jul 05; 309:9-14. . View in PubMed

Downregulation of cortical inhibition mediates ocular dominance plasticity during the critical period J Neurosci. 2013 Jul 03; 33(27):11276-80. . View in PubMed

DNA methylation and MeCP2 regulation of PTCH1 expression during rats hepatic fibrosis Cell Signal. 2013 May; 25(5):1202-11. . View in PubMed

Synaptic mechanisms underlying functional dichotomy between intrinsic-bursting and regular-spiking neurons in auditory cortical layer 5 J Neurosci. 2013 Mar 20; 33(12):5326-39. . View in PubMed

Generation of intensity selectivity by differential synaptic tuning: fast-saturating excitation but slow-saturating inhibition J Neurosci. 2012 Dec 12; 32(50):18068-78. . View in PubMed

Broadening of inhibitory tuning underlies contrast-dependent sharpening of orientation selectivity in mouse visual cortex J Neurosci. 2012 Nov 14; 32(46):16466-77. . View in PubMed

Generation of spike latency tuning by thalamocortical circuits in auditory cortex J Neurosci. 2012 Jul 18; 32(29):9969-80. . View in PubMed

Broadening of cortical inhibition mediates developmental sharpening of orientation selectivity J Neurosci. 2012 Mar 21; 32(12):3981-91. . View in PubMed

MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats Toxicology. 2011 Dec 18; 290(2-3):327-33. . View in PubMed

From elementary synaptic circuits to information processing in primary auditory cortex Neurosci Biobehav Rev. 2011 Nov; 35(10):2094-104. . View in PubMed

Perspectives on: information and coding in mammalian sensory physiology: inhibitory synaptic mechanisms underlying functional diversity in auditory cortex J Gen Physiol. 2011 Sep; 138(3):311-20. . View in PubMed

Broad inhibition sharpens orientation selectivity by expanding input dynamic range in mouse simple cells Neuron. 2011 Aug 11; 71(3):542-54. . View in PubMed

[Effect of allogenic adipose-derived stem cell grafting on serum biochemical indicators and sporting ability of endurance trained rats] Nan Fang Yi Ke Da Xue Xue Bao. 2011 Jun; 31(7):1159-63. . View in PubMed

Functional elimination of excitatory feedforward inputs underlies developmental refinement of visual receptive fields in zebrafish J Neurosci. 2011 Apr 06; 31(14):5460-9. . View in PubMed

Visual representations by cortical somatostatin inhibitory neurons--selective but with weak and delayed responses J Neurosci. 2010 Oct 27; 30(43):14371-9. . View in PubMed

Fine-tuning of pre-balanced excitation and inhibition during auditory cortical development Nature. 2010 Jun 17; 465(7300):927-31. . View in PubMed

Preceding inhibition silences layer 6 neurons in auditory cortex Neuron. 2010 Mar 11; 65(5):706-17. . View in PubMed

Intervening inhibition underlies simple-cell receptive field structure in visual cortex Nat Neurosci. 2010 Jan; 13(1):89-96. . View in PubMed

History matters: illuminating metaplasticity in the developing brain Neuron. 2009 Oct 29; 64(2):155-7. . View in PubMed

Visual receptive field structure of cortical inhibitory neurons revealed by two-photon imaging guided recording J Neurosci. 2009 Aug 26; 29(34):10520-32. . View in PubMed

A genetic strategy for stochastic gene activation with regulated sparseness (STARS) PLoS One. 2009; 4(1):e4200. . View in PubMed

Lateral sharpening of cortical frequency tuning by approximately balanced inhibition Neuron. 2008 Apr 10; 58(1):132-43. . View in PubMed

Defining cortical frequency tuning with recurrent excitatory circuitry Nat Neurosci. 2007 Dec; 10(12):1594-600. . View in PubMed

Heterosynaptic scaling of developing GABAergic synapses: dependence on glutamatergic input and developmental stage J Neurosci. 2007 May 16; 27(20):5301-12. . View in PubMed

Vesicular glutamate transport at a central synapse limits the acuity of visual perception in zebrafish Neuron. 2007 Jan 04; 53(1):65-77. . View in PubMed

Nonmonotonic synaptic excitation and imbalanced inhibition underlying cortical intensity tuning Neuron. 2006 Nov 22; 52(4):705-15. . View in PubMed

Activity-dependent matching of excitatory and inhibitory inputs during refinement of visual receptive fields Neuron. 2005 Mar 24; 45(6):829-36. . View in PubMed

The assembly of neural circuits Neuron. 2004 Jul 22; 43(2):159-63. . View in PubMed

Reversal and stabilization of synaptic modifications in a developing visual system Science. 2003 Jun 20; 300(5627):1953-7. . View in PubMed

Moving visual stimuli rapidly induce direction sensitivity of developing tectal neurons Nature. 2002 Oct 03; 419(6906):470-5. . View in PubMed

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