Iris A Perez, MD

Congenital central hypoventilation syndrome; pediatric sleep related breathing disorders, sleep in autism; diaphragm pacing; noninvasive positive pressure ventilation, home mechanical ventilation

• ATS Pediatric Core Curriculum 2024: The Role of the Pediatric Pulmonologist in the Intensive Care Unit. Pediatr Pulmonol. 2025 Oct; 60(10):e71329.. View in PubMed
• Sleep-related breathing disorders in infants with spina bifida repaired prenatally and postnatally. J Clin Sleep Med. 2024 Oct 01; 20(10):1579-1583.. View in PubMed
• Sleep disorders in pediatric patients with agenesis of the corpus callosum. J Clin Sleep Med. 2024 Oct 01; 20(10):1663-1667.. View in PubMed
• Congenital Central Hypoventilation Syndrome and Disorders of Control of Ventilation. Clin Chest Med. 2024 Sep; 45(3):663-673.. View in PubMed
• ATS core curriculum 2023. Pediatric pulmonary medicine: Respiratory disorders in infants. Pediatr Pulmonol. 2024 Jun; 59(6):1552-1568.. View in PubMed
• Elevated transaminases in congenital central hypoventilation syndrome. ERJ Open Res. 2024 Jan; 10(1).. View in PubMed
• When to panic about a panic attack: A challenging case of hypersensitivity pneumonitis. Paediatr Respir Rev. 2023 Dec; 48:20-23.. View in PubMed
• Obstructive sleep apnea as a presentation of congenital central hypoventilation syndrome. J Clin Sleep Med. 2023 09 01; 19(9):1697-1700.. View in PubMed
• Congenital central hypoventilation syndrome without hypoventilation: is it congenital central hypoventilation syndrome? J Clin Sleep Med. 2023 06 01; 19(6):1161-1164.. View in PubMed
• Transitional care and clinical management of adolescents, young adults, and suspected new adult patients with congenital central hypoventilation syndrome. Clin Auton Res. 2023 Jun; 33(3):231-249.. View in PubMed
• Perioperative outcomes and the effects of anesthesia in congenital central hypoventilation patients. Sleep Breath. 2023 05; 27(2):505-510.. View in PubMed
• Sleep Consequences of Prader-Willi Syndrome. Curr Neurol Neurosci Rep. 2023 03; 23(3):25-32.. View in PubMed
• Children with Congenital Central Hypoventilation Syndrome Do Not Wake up to Ventilator Alarms. Sleep Breath. 2022 09; 26(3):1277-1280.. View in PubMed
• An unusual cause of diaphragm pacer failure in congenital central hypoventilation syndrome. J Clin Sleep Med. 2022 Mar 01; 18(3):949-952.. View in PubMed
• Does acute flaccid myelitis cause respiratory failure in children? Pediatr Pulmonol. 2022 03; 57(3):682-685.. View in PubMed
• Variable phenotypes in congenital central hypoventilation syndrome with PHOX2B nonpolyalanine repeat mutations. J Clin Sleep Med. 2021 10 01; 17(10):2049-2055.. View in PubMed
• What Is Adaptive Servo-Ventilation (ASV)? Am J Respir Crit Care Med. 2021 07 15; 204(2):P3-P4.. View in PubMed
• Correction to: Hirschsprung disease and other gastrointestinal motility disorders in patients with CCHS. Eur J Pediatr. 2021 Feb; 180(2):475.. View in PubMed
• Hirschsprung disease and other gastrointestinal motility disorders in patients with CCHS. Eur J Pediatr. 2021 Feb; 180(2):469-473.. View in PubMed
• Pregnancy in congenital central hypoventilation syndrome. Am J Obstet Gynecol MFM. 2020 11; 2(4):100237.. View in PubMed
• Assessing the effects of sleep on neurocognitive performance and injury rate in adolescent athletes using actigraphy. Res Sports Med. 2020 Oct-Dec; 28(4):498-506.. View in PubMed
• Correction to: Life-threatening cardiac arrhythmias in congenital central hypoventilation syndrome. Eur J Pediatr. 2020 07; 179(7):1173.. View in PubMed
• Life-threatening cardiac arrhythmias in congenital central hypoventilation syndrome. Eur J Pediatr. 2020 May; 179(5):821-825.. View in PubMed
• Positional impairment of gas exchange during diaphragm pacing alleviated by increasing amplitude settings in congenital central hypoventilation syndrome. J Clin Sleep Med. 2020 03 15; 16(3):459-462.. View in PubMed
• Association between REM sleep and obstructive sleep apnea in obese and overweight adolescents. Sleep Breath. 2019 Jun; 23(2):645-650.. View in PubMed
• Adult With PHOX2B Mutation and Late-Onset Congenital Central Hypoventilation Syndrome. J Clin Sleep Med. 2018 12 15; 14(12):2079-2081.. View in PubMed
• Sleep in Infants. Am J Respir Crit Care Med. 2018 10 15; 198(8):P15-P16.. View in PubMed
• Sleep and Performance. Am J Respir Crit Care Med. 2018 04 15; 197(8):P13-P14.. View in PubMed
• Congenital central hypoventilation syndrome: diagnosis and management. Expert Rev Respir Med. 2018 04; 12(4):283-292.. View in PubMed
• Obstructive Sleep Apnea in Patients With Congenital Central Hypoventilation Syndrome Ventilated by Diaphragm Pacing Without Tracheostomy. J Clin Sleep Med. 2018 02 15; 14(2):261-264.. View in PubMed
• The genetics of congenital central hypoventilation syndrome: clinical implications. Appl Clin Genet. 2018; 11:135-144.. View in PubMed
• Three-Generation Family With Congenital Central Hypoventilation Syndrome and Novel PHOX2B Gene Non-Polyalanine Repeat Mutation. J Clin Sleep Med. 2017 Jul 15; 13(7):925-927.. View in PubMed
• Healthy Sleep in Children. Am J Respir Crit Care Med. 2017 03 15; 195(6):P11-P12.. View in PubMed
• Disorders of Sleep and Ventilatory Control in Prader-Willi Syndrome. Diseases. 2016 Jul 08; 4(3).. View in PubMed
• PATIENT EDUCATION | INFORMATION SERIES. Diaphragm Pacing by Phrenic Nerve Stimulation. Am J Respir Crit Care Med. 2016 Apr 15; 193(8):P13-4.. View in PubMed
• Congenital central hypoventilation syndrome: diagnostic and management challenges. Pediatric Health Med Ther. 2016; 7:99-107.. View in PubMed
• Diaphragm Pacing without Tracheostomy in Congenital Central Hypoventilation Syndrome Patients. Respiration. 2015; 89(6):534-8.. View in PubMed
• Thoracoscopic placement of phrenic nerve pacers for diaphragm pacing in congenital central hypoventilation syndrome. J Pediatr Surg. 2015 Jan; 50(1):78-81.. View in PubMed
• Persistent pneumonia in an infant. Keeping an open mind. Ann Am Thorac Soc. 2013 Oct; 10(5):514-7.. View in PubMed
• Peripheral chemoreceptors in congenital central hypoventilation syndrome. Respir Physiol Neurobiol. 2013 Jan 01; 185(1):186-93.. View in PubMed
• Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev. 2011 Sep 07; (9):CD001817.. View in PubMed
• Thoracoscopic pneumonectomy for severe bronchiectasis in a 9-year-old female. J Laparoendosc Adv Surg Tech A. 2008 Oct; 18(5):775-7.. View in PubMed
• The snoring child. Pediatr Ann. 2008 Jul; 37(7):465-70.. View in PubMed
• Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev. 2002; (1):CD001817.. View in PubMed
• Diuretics and chronic lung disease of prematurity. J Perinatol. 2001 Jul-Aug; 21(5):269-71.. View in PubMed
• Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev. 2000; (2):CD001817.. View in PubMed
• Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev. 2000; (3):CD001817.. View in PubMed
• Safety of hospitalized ventilator-dependent children outside of the intensive care unit. Pediatrics. 1998 Feb; 101(2):257-9.. View in PubMed

• Keens, Thomas
• Kezirian, Eric
• Shin, Cathy
• Khemani, Robinder
• Demetriades, Demetrios
• Castriotta, Richard
• Buckley, Jonathan
• Ward, Sally