J. Perren Cobb, MD

Professor of Surgery (Clinical Scholar)

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Overview

J. Perren Cobb is one of the preeminent experts in the field of critical care surgery and medicine and is director of the surgical intensive care unit at Keck Medical Center.

Dr. Cobb’s academic career started at Washington University in St. Louis, MO where he was appointed Assistant Professor in the burn, trauma, surgical critical care section of the Dept. of Surgery in 1995. Over the subsequent 14 years, Dr. Cobb achieved the rank of full professor with a joint appointment in the Department of Anesthesiology before leaving for Harvard Medical School in 2009 where he held a joint appointment in the Departments of Surgery and Anesthesiology. In 2015, Dr. Cobb moved to the west coast to assume a professorship in surgery at the Keck School of Medicine of USC.

Among the more salient points in Dr. Cobb’s impressive curriculum vitae are the pivotal and outstanding leadership roles in research he’s handled masterfully and the innovative and truly game-changing contributions he’s made in the field of Critical Care Surgery. He is the founding director of the United States Critical Illness and Injury Trials Group (USCIIT) and heads the USC Critical Care Institute, both of which are geared toward improving outcomes for the critically ill and injured through transformative biomedical research and performance improvement. He is single minded in his dedication to improving the delivery of care in the ICU across the nation through published chapters on Critical Care in standard textbooks and manuals and through countless national and international lectures.

Dr. Cobb’s extensive leadership in this field ensures that Keck Medical Center will continue to advance in providing excellent critical care to patients and their families.

Publications

  • Lessons Learned From a Systematic, Hospital-Wide Implementation of the ABCDEF Bundle: A Survey Evaluation Crit Care Explor. 2023 Nov; 5(11):e1007. . View in PubMed
  • Centers for Disease Control (CDC) Wound Classification is Prognostic of 30-Day Readmission Following Surgery World J Surg. 2023 10; 47(10):2392-2400. . View in PubMed
  • The impact of rounds with a psychiatry team in the intensive care unit: A prospective observational pilot study evaluating the effects on delirium incidence and outcomes J Psychiatr Res. 2023 04; 160:64-70. . View in PubMed
  • Crisis Triage in the Era of COVID-19: Old Tools, New Approaches, and Unanswered Questions Crit Care Med. 2023 01 01; 51(1):148-150. . View in PubMed
  • Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity Crit Care Explor. 2023 Jan; 5(1):e0827. . View in PubMed
  • Perceived Hospital Stress, Severe Acute Respiratory Syndrome Coronavirus 2 Activity, and Care Process Temporal Variance During the COVID-19 Pandemic Crit Care Med. 2023 04 01; 51(4):445-459. . View in PubMed
  • Critical Care Response During the COVID-19 Pandemic Crit Care Clin. 2022 Jul; 38(3):623-637. . View in PubMed
  • An Electronic Data Capture Tool for Data Collection During Public Health Emergencies: Development and Usability Study JMIR Hum Factors. 2022 Jun 09; 9(2):e35032. . View in PubMed
  • Improving ABCDEF Bundle Compliance and Clinical Outcomes in the ICU: Randomized Control Trial to Assess the Impact of Performance Measurement, Feedback, and Data Literacy Training Crit Care Explor. 2022 Apr; 4(4):e0679. . View in PubMed
  • Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC-WHO clinical characterisation protocol PLoS Med. 2022 04; 19(4):e1003969. . View in PubMed
  • ICU Resource Limitations During Peak Seasonal Influenza: Results of a 2018 National Feasibility Study Crit Care Explor. 2022 Jan; 4(1):e0606. . View in PubMed
  • Cognitive task analysis-based training in surgery: a meta-analysis BJS Open. 2021 11 09; 5(6). . View in PubMed
  • Complications Following Brachial Arterial Catheterization in the Surgical Intensive Care Unit Am Surg. 2020 Oct; 86(10):1260-1263. . View in PubMed
  • Fluid Resuscitation and Vasopressors in Septic Shock: The Importance of Filling the Tank While Squeezing the Pipes Crit Care Med. 2020 10; 48(10):1533-1535. . View in PubMed
  • The pharmacist’s role in disaster research response Am J Health Syst Pharm. 2020 06 23; 77(13):1054-1059. . View in PubMed
  • Clinical Investigation During Public Health Emergencies: The Resilience Intelligence Network Am J Public Health. 2019 09; 109(S4):S268-S270. . View in PubMed
  • Variability in intensive care unit length of stay after liver transplant: Determinants and potential opportunities for improvement J Crit Care. 2019 04; 50:296-302. . View in PubMed
  • Nosocomial Pneumonia in the ICU: Still More Questions Than Answers Crit Care Med. 2019 03; 47(3):472-473. . View in PubMed
  • Development of a Process and Infrastructure to Outreach Stakeholders for Capturing Healthcare System Stress in Emergency Response Situations Online J Public Health Inform. 2019; 11(2):e2. . View in PubMed
  • Balanced blood product transfusion during liver transplantation Clin Transplant. 2018 03; 32(3):e13191. . View in PubMed
  • Plasma 25-Hydroxyvitamin D Levels at Initiation of Care and Duration of Mechanical Ventilation in Critically Ill Surgical Patients JPEN J Parenter Enteral Nutr. 2016 Feb; 40(2):273-8. . View in PubMed
  • Survey of Annual Staffing Workloads for Adult Critical Care Physicians Working in the United States Ann Am Thorac Soc. 2016 05; 13(5):751-3. . View in PubMed
  • Development of a Core Clinical Dataset to Characterize Serious Illness, Injuries, and Resource Requirements for Acute Medical Responses to Public Health Emergencies Crit Care Med. 2015 Nov; 43(11):2403-8. . View in PubMed
  • Advanced imaging use in intensive care units has decreased, resulting in lower charges without negative effects on patient outcomes J Crit Care. 2015 Jun; 30(3):460-4. . View in PubMed
  • Global participation in core data sets for emerging pathogens Am J Respir Crit Care Med. 2015 Apr 01; 191(7):728-30. . View in PubMed
  • Clustering analysis to identify distinct spectral components of encephalogram burst suppression in critically ill patients Annu Int Conf IEEE Eng Med Biol Soc. 2015; 2015:7258-61. . View in PubMed
  • Assessment of satisfaction with care among family members of survivors in a neuroscience intensive care unit J Neurosci Nurs. 2014 Apr; 46(2):106-16. . View in PubMed
  • Anxiety and depression symptoms among families of adult intensive care unit survivors immediately following brief length of stay J Crit Care. 2014 Apr; 29(2):278-82. . View in PubMed
  • Consistency of communication among intensive care unit staff as perceived by family members of patients surviving to discharge J Crit Care. 2014 Feb; 29(1):134-8. . View in PubMed