J. Perren Cobb, MD

Professor of Surgery (Clinical Scholar)

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Overview

J. Perren Cobb is one of the preeminent experts in the field of critical care surgery and medicine and is director of the surgical intensive care unit at Keck Medical Center.

Dr. Cobb’s academic career started at Washington University in St. Louis, MO where he was appointed Assistant Professor in the burn, trauma, surgical critical care section of the Dept. of Surgery in 1995. Over the subsequent 14 years, Dr. Cobb achieved the rank of full professor with a joint appointment in the Department of Anesthesiology before leaving for Harvard Medical School in 2009 where he held a joint appointment in the Departments of Surgery and Anesthesiology. In 2015, Dr. Cobb moved to the west coast to assume a professorship in surgery at the Keck School of Medicine of USC.

Among the more salient points in Dr. Cobb’s impressive curriculum vitae are the pivotal and outstanding leadership roles in research he’s handled masterfully and the innovative and truly game-changing contributions he’s made in the field of Critical Care Surgery. He is the founding director of the United States Critical Illness and Injury Trials Group (USCIIT) and heads the USC Critical Care Institute, both of which are geared toward improving outcomes for the critically ill and injured through transformative biomedical research and performance improvement. He is single minded in his dedication to improving the delivery of care in the ICU across the nation through published chapters on Critical Care in standard textbooks and manuals and through countless national and international lectures.

Dr. Cobb’s extensive leadership in this field ensures that Keck Medical Center will continue to advance in providing excellent critical care to patients and their families.

Publications

  • Extending the Observational Medical Outcomes Partnership (OMOP) Common Data Model for Critical Care Medicine: A Framework for Standardizing Complex ICU Data Using the Society of Critical Care Medicine’s Critical Care Data Dictionary (C2D2). Crit Care Med. 2026 02 01; 54(2):270-279.. View in PubMed
  • Development of a Core Critical Care Data Dictionary With Common Data Elements to Characterize Critical Illness and Injuries Using a Modified Delphi Method. Crit Care Med. 2025 May 01; 53(5):e1045-e1054.. View in PubMed
  • Guiding Principles for Data Sharing and Harmonization: Results of a Systematic Review and Modified Delphi From the Society of Critical Care Medicine Data Science Campaign. Crit Care Med. 2025 Mar 01; 53(3):e619-e631.. View in PubMed
  • Lessons Learned From a Systematic, Hospital-Wide Implementation of the ABCDEF Bundle: A Survey Evaluation. Crit Care Explor. 2023 Nov; 5(11):e1007.. View in PubMed
  • Centers for Disease Control (CDC) Wound Classification is Prognostic of 30-Day Readmission Following Surgery. World J Surg. 2023 10; 47(10):2392-2400.. View in PubMed
  • Perceived Hospital Stress, Severe Acute Respiratory Syndrome Coronavirus 2 Activity, and Care Process Temporal Variance During the COVID-19 Pandemic. Crit Care Med. 2023 04 01; 51(4):445-459.. View in PubMed
  • The impact of rounds with a psychiatry team in the intensive care unit: A prospective observational pilot study evaluating the effects on delirium incidence and outcomes. J Psychiatr Res. 2023 04; 160:64-70.. View in PubMed
  • Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity. Crit Care Explor. 2023 Jan; 5(1):e0827.. View in PubMed
  • Crisis Triage in the Era of COVID-19: Old Tools, New Approaches, and Unanswered Questions. Crit Care Med. 2023 01 01; 51(1):148-150.. View in PubMed
  • An Electronic Data Capture Tool for Data Collection During Public Health Emergencies: Development and Usability Study. JMIR Hum Factors. 2022 Jun 09; 9(2):e35032.. View in PubMed