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James Buxbaum, MD

Professor of Medicine (Clinical Scholar)

Executive Director, Digestive Health Institute, Keck Medicine of USC

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Phone +1 323 409 5371
Email [email protected]
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Overview

Dr. Buxbaum brings a clinical and research interest in advanced endoscopic topics and pancreatology to the University of Southern California. His research interests include the development of biomarkers for and the endoscopic management of pancreatic neoplasms. He also has a special interest in complex biliary problems including recurrent pyogenic cholangitis and post liver transplant strictures.

Dr. Buxbaum earned his medical degree from University of California, San Francisco, then went on to complete two fellowships also at UCSF, one in gastroenterology and the other in advanced endoscopy.

Awards

  • American Society for Gastrointestinal Endoscopy: Fellow, 2014
  • Pasadena Magazine: Top Doctor, 2011
  • UCSF: Molecular Medicine Fellow, 2004
  • Stanford University: Phi Beta Kappa & Presidential Scholar, 1999

Publications

  • Hyperglycemia During Acute Pancreatitis and Progression to Early-Onset Diabetes After Recovery: Preliminary Findings From the Diabetes Related to Acute Pancreatitis and Its Mechanisms (DREAM) Study. Diabetes Care. 2026 Jun 01; 49(6):1040-1047.. View in PubMed
  • Hierarchical organ aging signatures from routine abdominal CT add incremental disease risk stratification beyond blood biomarkers. medRxiv. 2026 May 27.. View in PubMed
  • Differentiating Immunoglobulin G4-Related Sclerosing Cholangitis From Primary Sclerosing Cholangitis: A Comprehensive Systematic Review and Meta-Analysis of Diagnostic Features. Am J Gastroenterol. 2026 Apr 16.. View in PubMed
  • Response. Gastrointest Endosc. 2026 Apr; 103(4):822-823.. View in PubMed
  • Associations between dietary patterns and diabetes in patients with acute pancreatitis: a cross-sectional analysis from the DREAM study. Nutr J. 2026 Mar 27; 25(1).. View in PubMed
  • DNA/RNA-Based Next-Generation Sequencing Improves the Early Diagnosis and Management of Neoplastic Bile Duct Strictures: A 6-Year, Prospective, Multi-Institutional, Real-Time Study. Gastroenterology. 2026 Mar 27.. View in PubMed
  • Minor Papillotomy for Treatment of Idiopathic Acute Pancreatitis With Pancreas Divisum: A Randomized Clinical Trial. JAMA. 2026 02 24; 335(8):682-692.. View in PubMed
  • Zegocractin for acute pancreatitis with systemic inflammatory response syndrome: a randomized, controlled, dose-ranging, phase 2b trial. EClinicalMedicine. 2026 Mar; 93:103757.. View in PubMed
  • Updates From the 2025 IAP Acute Pancreatitis Guidelines. Pancreas. 2026 Feb 01; 55(2):e147-e149.. View in PubMed
  • Temporal Changes in Quality of Life in Patients With Alcohol-Associated Acute Pancreatitis. Pancreas. 2026 01 01; 55(1):e15-e20.. View in PubMed

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