James Jeffrey Cox

Clinical Instructor of Psychiatry and the Behavioral Sciences (Practitioner)

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Publications

Nav1.5 in the dorsal root ganglion plays a crucial role in mechanical hypersensitivity. Brain. 2026 Jul 07; 149(7):2516-2532.. View in PubMed
Natural antisense transcript Nat9a suppresses Scn9a (NaV1.7) expression in parvalbumin-positive proprioceptive and inhibitory neurons. Sci Rep. 2026 Apr 16; 16(1).. View in PubMed
MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain. Proc Natl Acad Sci U S A. 2025 Nov 11; 122(45):e2512426122.. View in PubMed
Intrathecal administration of the Nav1.7 inhibitor PF-05089771 produces rapid and side-effect-free analgesia in mice. Pain. 2026 Mar 01; 167(3):589-605.. View in PubMed
Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine). J Gen Physiol. 2025 07 07; 157(4).. View in PubMed
Sodium channels Nav1.7, Nav1.8 and pain; two distinct mechanisms for Nav1.7 null analgesia. Neurobiol Pain. 2024 Jul-Dec; 16:100168.. View in PubMed
Novel therapies for cancer-induced bone pain. Neurobiol Pain. 2024 Jul-Dec; 16:100167.. View in PubMed
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes. Cell Rep. 2024 08 27; 43(8):114614.. View in PubMed
Out of the dark: the emerging roles of lncRNAs in pain. Trends Genet. 2024 08; 40(8):694-705.. View in PubMed
Transcriptomic profiling reveals a pronociceptive role for angiotensin II in inflammatory bowel disease. Pain. 2024 Jul 01; 165(7):1592-1604.. View in PubMed