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Janet Oldak, BSc, MSc, PhD

Professor

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Phone +1 323 442 1759
Email [email protected]
CTSI Profile

Research Funding

  • Monetite-Apatite Phase Transformation for an Enamel-Like Restorative Material
    NIH · R21DE027529 · Mar 15, 2019 – Feb 27, 2021 · Role: Principal Investigator
  • A Peptide-Based Biomineralization Strategy for Tooth Repair
    NIH · R01DE027632 · Feb 1, 2019 – Jan 31, 2024 · Role: Principal Investigator
  • TENTH INTERNATIONAL CONFERENCE ON THE CHEMISTRY AND BIOLOGY OF MINERALIZED TISSUE
    NIH · R13DE020993 · May 1, 2010 – Apr 30, 2012 · Role: Principal Investigator
  • INTRINSICALLY DISORDERED PROTEINS IN BIOMINERALIZATION
    NIH · R01DE020099 · Sep 25, 2009 – Aug 31, 2016 · Role: Principal Investigator
  • ACTION AND FUNCTION OF MMP-20 DURING ENAMEL FORMATION
    NIH · R01DE015644 · Sep 1, 2005 – Aug 31, 2010 · Role: Principal Investigator
  • A NEW STRATEGY FOR AMELOGENIN CYRSTALLIZATION
    NIH · R21DE015332 · Sep 1, 2003 – Jun 30, 2006 · Role: Principal Investigator
  • MATRIX BASED MINERAL ENAMEL-BIOMIMETICS
    NIH · R56DE013414 · Sep 19, 2001 – Apr 30, 2019 · Role: Principal Investigator
  • MATRIX BASED MINERAL ENAMEL-BIOMIMETICS
    NIH · R01DE013414 · Dec 1, 1999 – Apr 30, 2029 · Role: Principal Investigator
  • AMELOGENIN PROCESSING AND APATITE CRYSTAL GROWTH
    NIH · R29DE012350 · Apr 1, 1998 – Mar 31, 2003 · Role: Principal Investigator

Publications

  • Ameloblastin binding to biomimetic models of cell membranes – A continuum of intrinsic disorder. Arch Oral Biol. 2025 Jan; 169:106124.. View in PubMed
  • Deletion within ameloblastin multitargeting domain reduces its interaction with artificial cell membrane. J Struct Biol. 2024 Dec; 216(4):108143.. View in PubMed
  • Ameloblastin and its multifunctionality in amelogenesis: A review. Matrix Biol. 2024 08; 131:62-76.. View in PubMed
  • Ameloblastin promotes polarization of ameloblast cell lines in a 3-D cell culture system. Matrix Biol. 2022 01; 105:72-86.. View in PubMed
  • Peptide-Mediated Biomimetic Regrowth of Human Enamel In Situ. Methods Mol Biol. 2019; 1922:129-138.. View in PubMed
  • The Expression and Purification of Recombinant Mouse Ameloblastin in E. coli. Methods Mol Biol. 2019; 1922:229-236.. View in PubMed
  • Immunohistochemical Co-Localization of Amelogenin and Ameloblastin in Developing Enamel Matrix. Methods Mol Biol. 2019; 1922:219-228.. View in PubMed
  • Amelogenin-Ameloblastin Spatial Interaction around Maturing Enamel Rods. J Dent Res. 2016 08; 95(9):1042-8.. View in PubMed
  • Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals. Biomaterials. 2016 Jan; 75:260-270.. View in PubMed
  • Tooth enamel protein amelogenin binds to ameloblast cell membrane-mimicking vesicles via its N-terminus. Biochem Biophys Res Commun. 2015 Aug 28; 464(3):956-61.. View in PubMed
  • Development of amelogenin-chitosan hydrogel for in vitro enamel regrowth with a dense interface. J Vis Exp. 2014 Jul 10.. View in PubMed
  • Protein-mediated enamel mineralization. Front Biosci (Landmark Ed). 2012 06 01; 17(6):1996-2023.. View in PubMed
  • The emergence of “nanospheres” as basic structural components adopted by amelogenin. J Dent Res. 2007 Jun; 86(6):487-90.. View in PubMed
  • On the formation of amelogenin microribbons. Eur J Oral Sci. 2006 May; 114.. View in PubMed
  • Amelogenin supra-molecular assembly in vitro compared with the architecture of the forming enamel matrix. Cells Tissues Organs. 2005; 181(3-4):202-18.. View in PubMed
  • Assembly of amelogenin proteolytic products and control of octacalcium phosphate crystal morphology. Connect Tissue Res. 2003; 44.. View in PubMed
  • Structural and stereochemical relations between acidic macromolecules of organic matrices and crystals. Connect Tissue Res. 1989; 21(1-4):127-34.. View in PubMed

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