Keck School Faculty

Janice M. Liebler

Janice M. Liebler

Professor of Clinical Medicine
IRD 720 2020 Zonal Avenue Health Sciences Campus Los Angeles

OHSU Foundation: Donor Research Grant, 1992-1999

American Lung Association of Oregon: Research Grant, 1989

Medical Research Foundation of Oregon: Research Grant , 1987

Medical Research Foundation of Oregon: Research Grant, 1987

San Jacinto Lung Association: Training Research Grant, 1981

Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study Chest. 2021 10; 160(4):1304-1315. . View in PubMed

Evaluation of Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments JAMA Intern Med. 2021 06 01; 181(6):786-794. . View in PubMed

Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020) Eur Respir Rev. 2020 Sep 30; 29(157). . View in PubMed

Super Obesity in the Medical Intensive Care Unit J Intensive Care Med. 2020 May; 35(5):478-484. . View in PubMed

Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses to Reduce Nonbeneficial Intensive Care Unit Treatments: Protocol for a Multicenter Quality Improvement Study JMIR Res Protoc. 2019 Nov 25; 8(11):e16301. . View in PubMed

Circulating angiotensin peptides levels in Acute Respiratory Distress Syndrome correlate with clinical outcomes: A pilot study PLoS One. 2019; 14(3):e0213096. . View in PubMed

Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis J Clin Invest. 2018 03 01; 128(3):970-984. . View in PubMed

Region-specific role for Pten in maintenance of epithelial phenotype and integrity Am J Physiol Lung Cell Mol Physiol. 2017 01 01; 312(1):L131-L142. . View in PubMed

Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung Am J Physiol Lung Cell Mol Physiol. 2016 Jan 15; 310(2):L114-20. . View in PubMed

Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance Am J Respir Cell Mol Biol. 2016 09; 55(3):395-406. . View in PubMed

Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study Crit Care Med. 2015 Oct; 43(10):2076-84. . View in PubMed

Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis Am J Respir Cell Mol Biol. 2014 Aug; 51(2):210-22. . View in PubMed

Interactions between ß-catenin and transforming growth factor-ß signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP) J Biol Chem. 2012 Mar 02; 287(10):7026-38. . View in PubMed

Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury Am J Physiol Lung Cell Mol Physiol. 2008 Aug; 295(2):L285-92. . View in PubMed

Rat aquaporin-5 43-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C111-20. . View in PubMed

Developmental pathways and specification of intrapulmonary stem cells Pediatr Res. 2006 Apr; 59(4 Pt 2):84R-93R. . View in PubMed

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis Am J Pathol. 2005 May; 166(5):1321-32. . View in PubMed

Alveolar epithelial type I cells express beta2-adrenergic receptors and G-protein receptor kinase 2 J Histochem Cytochem. 2004 Jun; 52(6):759-67. . View in PubMed

Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer Hum Gene Ther. 2004 May; 15(5):457-68. . View in PubMed

Foxj1 is required for apical localization of ezrin in airway epithelial cells J Cell Sci. 2003 Dec 15; 116(Pt 24):4935-45. . View in PubMed

Modulation of ion conductance and active transport by TGF-beta 1 in alveolar epithelial cell monolayers Am J Physiol Lung Cell Mol Physiol. 2003 Dec; 285(6):L1192-200. . View in PubMed

Identification of three genes of known function expressed by alveolar epithelial type I cells Am J Respir Cell Mol Biol. 2003 Jul; 29(1):98-105. . View in PubMed

Na transport proteins are expressed by rat alveolar epithelial type I cells Am J Physiol Lung Cell Mol Physiol. 2002 Apr; 282(4):L599-608. . View in PubMed

Ultrastructural immunolocalization of basic fibroblast growth factor in mast cell secretory granulesMorphological evidence for bfgf release through degranulation. J Histochem Cytochem. 1998 Oct; 46(10):1119-28. . View in PubMed

Expression of basic fibroblast growth factor in nasal polyps Ann Otol Rhinol Laryngol. 1998 Oct; 107(10 Pt 1):891-7. . View in PubMed

Fibroproliferation and mast cells in the acute respiratory distress syndrome Thorax. 1998 Oct; 53(10):823-9. . View in PubMed

Synthesis of basic fibroblast growth factor by murine mast cellsRegulation by transforming growth factor beta, tumor necrosis factor alpha, and stem cell factor. Int Arch Allergy Immunol. 1998 Jan; 115(1):47-54. . View in PubMed

Altered immunohistochemical localization of basic fibroblast growth factor after bleomycin-induced lung injury Growth Factors. 1997; 14(1):25-38. . View in PubMed

Invasive line placement in critically ill patients: do hemostatic defects matter? Transfusion. 1996 Sep; 36(9):827-31.. View in PubMed

Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma Am J Pathol. 1995 Sep; 147(3):564-73. . View in PubMed

Gene expression of macrophage inflammatory protein-1 alpha from human blood monocytes and alveolar macrophages is inhibited by interleukin-4 Am J Respir Cell Mol Biol. 1993 Aug; 9(2):192-8. . View in PubMed

Respiratory complications in critically ill medical patients with acute upper gastrointestinal bleeding Crit Care Med. 1991 Sep; 19(9):1152-7. . View in PubMed

Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells J Appl Physiol (1985). 2005 Jan; 98(1):322-8. . View in PubMed

Dr. Liebler hails from Detroit, MI where she attended medical school at Wayne State University. After coming to the USC Keck School of Medicine in 1999, Dr. Liebler has established herself as a leading educator in lung transplantation and critical care medicine. She was formally the Associate Medical Director for Keck’s Lung Transplantation Program and is currently an attending physician for both LAC+USC Medical Center’s Medical Intensive Care Unit and Keck Hospital of USC Pulmonary and Critical Care Medicine division. In addition to lung transplantation, Dr. Liebler research interests also include lung injury and repair and cell-based treatment of lung diseases.
sc ctsi logoPowered by SC CTSI