Overview

Understanding brain and spinal cord networks controlling muscle fibers with neuroimaging, electrophysiology, and mathematical models; optimizing rehabilitation for restoring normal control of muscle in individuals with chronic pain.

Research Funding

  • Individual differences in brain morphology and connectivity to identify the mechanisms of comorbidities and treatment-refractory disease in females with endometriosis-associated pelvic pain
    NIH · R01HD117775 · Aug 1, 2025 – Jul 31, 2028 · Role: Co-Principal Investigator
  • Motor cortical neuromodulation in women with Interstitial Cystitis/Bladder Pain Syndrome: reducing pain by improving brain and muscle activity
    NIH · R01DK121724 · Aug 15, 2020 – Apr 30, 2025 · Role: Principal Investigator
  • Sensorimotor impairments in men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: relationship of resting state brain activity to pelvic floor muscle activation
    NIH · R01DK110669 · Feb 1, 2017 – Jan 31, 2022 · Role: Principal Investigator
  • Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network Discovery Site
    NIH · U01DK082370 · Sep 15, 2008 – Jun 30, 2022 · Role: Co-Principal Investigator
  • Neuromechanics of Differential Motor Unit Activation in Multifunctional Muscles
    NIH · F31NS057855 · Feb 1, 2007 – Jan 31, 2010 · Role: Principal Investigator

Publications

  • Distinct connectivity patterns subserve 2 dimensions of the chronic pain experience. Pain. 2026 Sep 24.. View in PubMed
  • Association of widespread pain and peak alpha frequency cannot be isolated to a single network. Pain Rep. 2026 Jun; 11(3):e1436.. View in PubMed
  • Widespread Pain Moderates the Response to Centrally-Acting Therapies in an Observational Cohort of Patients With Urologic Chronic Pelvic Pain Syndrome: A MAPP Research Network Study. Neurourol Urodyn. 2025 Aug; 44(6):1290-1295.. View in PubMed
  • The Impact of Airflow and Multisensory Feedback on Immersion and Cybersickness in a VR Surfing Simulation. IEEE Trans Vis Comput Graph. 2025 May; 31(5):2445-2454.. View in PubMed
  • Peak alpha frequency is related to the degree of widespread pain, but not pain intensity or duration, among people with urologic chronic pelvic pain syndrome. Pain Rep. 2025 Apr; 10(2):e1251.. View in PubMed
  • Noninvasive brain stimulation beyond the motor cortex: a systematic review and meta-analysis exploring effects on quantitative sensory testing in clinical pain. Pain Med. 2025 Feb 01; 26(2):98-111.. View in PubMed
  • Preparing the brain for pain: new insights and potential biomarkers. Pain. 2025 Jun 01; 166(6):1221-1222.. View in PubMed
  • Brain predicted age in chronic pelvic pain: a study by the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network. Pain. 2025 May 01; 166(5):1060-1069.. View in PubMed
  • Peak alpha frequency differs between chronic back pain and chronic widespread pain. Eur J Pain. 2025 Mar; 29(3):e4737.. View in PubMed
  • Reducing pain by improving brain and muscle activity with motor cortical neuromodulation in women with interstitial cystitis/bladder pain syndrome: a study protocol for a randomized controlled trial. Trials. 2024 Sep 12; 25(1):609.. View in PubMed