Jay R. Lieberman, MD

Chair and Professor of Orthopaedic Surgery

Chief of Orthopaedic Surgery Service, Keck Medical Center

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Overview

Dr. Lieberman is professor and chair of the Department of Orthopaedic Surgery at the Keck School of Medicine of USC and the Director of the Institute of Orthopaedics at the Keck Medical Center of USC. Dr. Lieberman is internationally recognized for his expertise in primary and revision total hip and knee replacement and treatment of osteonecrosis (bone death) of the hip and knee. He is interested in improving outcomes and limiting complications after total hip and knee replacement. Dr. Lieberman wants to assess the influence of spirituality on the results of total joint replacement.
Dr. Lieberman is the Past President of both the American Association of Hip and Knee Surgeons and The Hip Society. He is also a member of The Knee Society, and The International Hip Society. He has been named multiple times to the Best Doctors in America list, Top Doctors and as a Southern California Super Doctor. He has co-edited three books for the American Academy of Orthopaedic Surgeons (AAOS) on surgical techniques related to total hip and knee arthroplasty and he has co-edited two editions of a popular text entitled “Surgery of the Hip”. He has published more than 300 manuscripts, book chapters and reviews. Dr. Lieberman has won numerous awards including the Frank Stinchfield Hip Society Award; the Orthopaedic Research Society’s Marshall Urist Award in recognition of his contribution to the field of tissue engineering; and the prestigious AAOS Elizabeth Winston Lanier Kappa Delta Award for his pioneering work related to the development of regional gene therapy to enhance bone repair. Dr. Lieberman received his medical degree from the Albany Medical College of Union University and completed his fellowship training in total joint replacement at The Hospital for Special Surgery in New York.

Awards

  • The HIP Society: Frank Stinchfield Hip Society Award, 2011
  • American Orthopaedic Association: ABC Traveling Fellowship, 2011
  • Orthopaedic Research Society: Marshall R. Urist Award for Excellence in Tissue Regeneration Research, 2011
  • American Academy of Orthopaedic Surgeons: Elizabeth Winston Lanier Kappa Delta Research Award, 2012
  • Keck School of Medicine: Outstanding Required Student Project Mentor Award, 2015
  • Los Angeles Magazine: Southern California Super Doctors, 2013
     – 2022
  • Castle Connolly: America’s Top Doctors, 2016
     – 2017
  • Castle Connolly: America’s Top Doctors, 2019
  • Pasadena Magazine: Top Doctor, 2013
     – 2015
  • Pasadena Magazine: Top Doctor, 2017
     – 2021

Research Funding

  • Regional Gene Therapy to Enhance Bone Repair
    NIH · R01AR057076 · Apr 1, 2010 – Mar 31, 2022 · Role: Principal Investigator
  • RANKL and BMPs in Prostate Cancer Induced Bone Lesions
    NIH · R01CA103039 · Sep 1, 2003 – Jun 30, 2009 · Role: Principal Investigator
  • Regional Gene Therapy to Enhance Bone Repair
    NIH · R01AR046789 · Apr 1, 2001 – Jan 31, 2005 · Role: Principal Investigator
  • RECOMBINANT BMP AND BONE FORMATION
    NIH · K11AR001931 · Sep 30, 1994 – Aug 31, 1999 · Role: Principal Investigator

Publications

  • Recognizing and treating serious allergic reactions (anaphylaxis) in infants and toddlers: a plain language review. Expert Rev Clin Immunol. 2026 Jul 30; 1.. View in PubMed
  • Perioperative Dexamethasone Is Associated With a Reduced Risk of Periprosthetic Joint Infection Following Aseptic Revision Total Hip and Knee Arthroplasty. Arthroplast Today. 2026 Aug; 40:102100.. View in PubMed
  • Predictive Factors for Manipulations Under Anesthesia After Total Knee Arthroplasty: An Analysis of 15,139 Cases. J Am Acad Orthop Surg. 2026 Jul 23.. View in PubMed
  • Nontraumatic Osteonecrosis of the Femoral Head: An Update. J Bone Joint Surg Am. 2026 Jul 20.. View in PubMed
  • The Impact of Standardized Letter of Recommendation Origin on Orthopedic Surgery Residency Match Outcomes. J Surg Educ. 2026 Jul 20; 83(9):104077.. View in PubMed
  • Dexamethasone is Associated with a Dose-Dependent Reduction in Venous Thromboembolic Complications following Total Knee and Hip Arthroplasty. J Arthroplasty. 2026 Jul 16.. View in PubMed
  • Combination ex vivo regional gene therapy with sonic hedgehog and bone morphogenetic protein-2 does not enhance bone healing in critical size defects. Connect Tissue Res. 2026 Jul 12; 1.. View in PubMed
  • Inflammatory Bowel Disease and Periprosthetic Joint Infection Following Total Joint Arthroplasty: Crohn’s Disease and Ulcerative Colitis Associated With Varying Risk. Arthroplast Today. 2026 Aug; 40:102077.. View in PubMed
  • Risk of Total Hip Arthroplasty After Sacroiliac Joint Fusion Surgery: A Nationwide Study. Global Spine J. 2026 Jul 02; 21925682261463491.. View in PubMed
  • Reassessing Total Joint Arthroplasty Case Volumes in the United States: Accounting for Ultralow-Volume Surgeons. J Arthroplasty. 2026 Jun 27.. View in PubMed