Jay R. Lieberman, MD

Chair and Professor of Orthopaedic Surgery

Chief of Orthopaedic Surgery Service, Keck Medical Center

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Overview

Dr. Lieberman is professor and chair of the Department of Orthopaedic Surgery at the Keck School of Medicine of USC and the Director of the Institute of Orthopaedics at the Keck Medical Center of USC. Dr. Lieberman is internationally recognized for his expertise in primary and revision total hip and knee replacement and treatment of osteonecrosis (bone death) of the hip and knee. He is interested in improving outcomes and limiting complications after total hip and knee replacement. Dr. Lieberman wants to assess the influence of spirituality on the results of total joint replacement.
Dr. Lieberman is the Past President of both the American Association of Hip and Knee Surgeons and The Hip Society. He is also a member of The Knee Society, and The International Hip Society. He has been named multiple times to the Best Doctors in America list, Top Doctors and as a Southern California Super Doctor. He has co-edited three books for the American Academy of Orthopaedic Surgeons (AAOS) on surgical techniques related to total hip and knee arthroplasty and he has co-edited two editions of a popular text entitled “Surgery of the Hip”. He has published more than 300 manuscripts, book chapters and reviews. Dr. Lieberman has won numerous awards including the Frank Stinchfield Hip Society Award; the Orthopaedic Research Society’s Marshall Urist Award in recognition of his contribution to the field of tissue engineering; and the prestigious AAOS Elizabeth Winston Lanier Kappa Delta Award for his pioneering work related to the development of regional gene therapy to enhance bone repair. Dr. Lieberman received his medical degree from the Albany Medical College of Union University and completed his fellowship training in total joint replacement at The Hospital for Special Surgery in New York.

Awards

  • The HIP Society: Frank Stinchfield Hip Society Award, 2011
  • American Orthopaedic Association: ABC Traveling Fellowship, 2011
  • Orthopaedic Research Society: Marshall R. Urist Award for Excellence in Tissue Regeneration Research, 2011
  • American Academy of Orthopaedic Surgeons: Elizabeth Winston Lanier Kappa Delta Research Award, 2012
  • Keck School of Medicine: Outstanding Required Student Project Mentor Award, 2015
  • Los Angeles Magazine: Southern California Super Doctors, 2013
     – 2022
  • Castle Connolly: America’s Top Doctors, 2016
     – 2017
  • Castle Connolly: America’s Top Doctors, 2019
  • Pasadena Magazine: Top Doctor, 2013
     – 2015
  • Pasadena Magazine: Top Doctor, 2017
     – 2021

Research Funding

  • Regional Gene Therapy to Enhance Bone Repair
    NIH · R01AR057076 · Apr 1, 2010 – Mar 31, 2022 · Role: Principal Investigator
  • RANKL and BMPs in Prostate Cancer Induced Bone Lesions
    NIH · R01CA103039 · Sep 1, 2003 – Jun 30, 2009 · Role: Principal Investigator
  • Regional Gene Therapy to Enhance Bone Repair
    NIH · R01AR046789 · Apr 1, 2001 – Jan 31, 2005 · Role: Principal Investigator
  • RECOMBINANT BMP AND BONE FORMATION
    NIH · K11AR001931 · Sep 30, 1994 – Aug 31, 1999 · Role: Principal Investigator

Publications

  • Sobering Outcomes after Two-Stage Revision for Periprosthetic Joint Infection Among Patients Who Have Revision Total Knee Arthroplasty Components. J Arthroplasty. 2026 Sep 19.. View in PubMed
  • Quantifying the Age-Dependent Risk of Periprosthetic Femoral Fracture Following Cementless Total Hip Arthroplasty: An Analysis using Age as a Continuous Variable. J Arthroplasty. 2026 Sep 15.. View in PubMed
  • Increased Polymicrobial Infection Rates and Associated Mortality in Patients With Chronic Gastrointestinal Disease Undergoing Antibiotic Spacer Placement for Periprosthetic Joint Infection. Arthroplast Today. 2026 Oct; 41:102140.. View in PubMed
  • Cirrhosis is associated with an increased risk of periprosthetic joint infection following total joint arthroplasty. J Clin Orthop Trauma. 2026 Nov; 82:103607.. View in PubMed
  • Identifying and Addressing Problematic Studies in Allergy and Asthma Research: A Commentary. J Allergy Clin Immunol Pract. 2026 Aug 25.. View in PubMed
  • Response to the Letter To The Editor Risk of Total Hip Arthroplasty After Sacroiliac Joint Fusion Surgery: A Nationwide Study. Global Spine J. 2026 Aug 19; 21925682261480678.. View in PubMed
  • Microbiologic Patterns Found in Periprosthetic Joint Infections Following Total Joint Arthroplasty Differ Across Race and Sex. Arthroplast Today. 2026 Aug; 40:102116.. View in PubMed
  • Tranexamic Acid Use Is Associated With Lower Rates of Transfusion in Patients Undergoing Revision Total Hip Arthroplasty for Periprosthetic Joint Infection. Arthroplast Today. 2026 Aug; 40:102106.. View in PubMed
  • High-Volume Hospitals Are Associated With Lower Rates of Mortality Following Revision Arthroplasty for Periprosthetic Joint Infection. Arthroplast Today. 2026 Aug; 40:102111.. View in PubMed
  • Linking Quality Measures to Guideline Recommendations in Allergy-Immunology: Challenges and Opportunities: A Workgroup Report of the AAAAI Measures Stewardship Committee. J Allergy Clin Immunol Pract. 2026 Aug; 14(8):1756-1771.. View in PubMed