Jeffrey Klausner, MD, MPH

Professor of Clinical Population and Public Health Sciences

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Overview

From 1998-2009 Dr. Klausner was a Deputy Health Officer, Director of STD Prevention and Control Services at the San Francisco Department of Public Health, member of the UCSF School of Medicine faculty in the Divisions of AIDS and Infectious Diseases and Attending Physician at San Francisco General Hospital. While in San Francisco Dr. Klausner helped identify key factors associated with the increased spread of HIV and STDs and implemented multiple novel public health prevention programs. He helped create the St. James Infirmary, the first occupational health and safety clinic for sex workers and Magnet, a community-based peer-run sexual health clinic for gay men.
From 2009-2011 Dr. Klausner was Branch Chief for HIV and TB at the Centers for Disease Control in Pretoria, South Africa, helping lead the South African PEPFAR program for care and treatment.

After returning from South Africa, from 2011-2021. Klausner was a senior faculty member in the UCLA Division of Infectious Diseases, David Geffen School of Medicine and the Department of Epidemiology at the Fielding School of Public health. At UCLA, Dr. Klausner was the Principal Investigator for multiple NIH-funded networks, projects and studies on sexually transmitted infections in Peru, Botswana, South Africa, Vietnam, Haiti, Pakistan and India antimicrobial resistance and HIV prevention.

Dr. Klausner’s research interests are in applied epidemiology and the prevention and control of infectious diseases of public health importance like HIV, STDs, TB, COVID-19 and cryptococcal infections. Dr. Klausner has a particular interest in the use of technology—information, digital, and laboratory—to facilitate access to treatment for disadvantaged populations. Dr. Klausner has been funded by the NIH, CDC, private pharmaceutical and test manufacturers to study the benefits of new ways to find and treat infectious diseases. Dr. Klausner is a frequent advisor to the CDC, NIH and WHO and a popular public speaker. Dr. Klausner is a highly sought after mentor who has trained dozens of fellows, residents and students of medicine and public health.

Awards

  • American STD Association: Young Investigator Award, 2001
     – 2001
  • Beyond AIDS: Nettie Award, 2008
     – 2008
  • Centers for Disease Control: Jack N. Spencer Award, 2016
     – 2016

Education and Training

  • Cornell University, Ithaca, NY — AB — 05/1986 — Chemistry and Art History
  • Cornell University Medicall College, New York City — MD — 05/1991 — Medicine
  • NYU-Bellevue Hospital, New York City — 06/1994 — Internal Medicine
  • Harvard University, Cambridge, MA — MPH — 05/1995 — Epidemiology and International Health
  • Centers for Disease Control and Prevention, Atlanta, GA — 06/1997 — Epidemic Intelligence Service
  • University of Washington, Seattle, WA — Fellow — 06/1998 — Infectious Diseases

Research Funding

  • STIs and Pre-Term Birth
    NIH · R03AI199976 · Jul 15, 2026 – Jun 30, 2028 · Role: Principal Investigator
  • V-STAR – Vietnam Research Training Program on Sexually Transmitted Diseases and Antimicrobial Resistance
    NIH · D43TW012743 · Jul 16, 2025 – Mar 31, 2030 · Role: Principal Investigator
  • Pilot study of linezolid for early syphilis treatment
    NIH · R21AI173988 · Nov 22, 2022 – Oct 31, 2024 · Role: Principal Investigator
  • Evaluating STI screening and antimicrobial resistance in Neisseria gonorrhoeae among PrEP users in Vietnam
    NIH · R21AI157817 · Feb 5, 2021 – Jan 31, 2024 · Role: Principal Investigator
  • Clinical Trial Comparing the Effectiveness of Cefixime Versus Penicillin G for Treatment of Early Syphilis
    NIH · R01AI155217 · Jul 13, 2020 – Jul 31, 2027 · Role: Principal Investigator
  • The diagnosis and treatment of Chlamydia trachomatis and Neisseria gonorrhoeae in pregnant women to prevent adverse neonatal consequences
    NIH · R21HD100821 · Feb 22, 2020 – Jan 31, 2022 · Role: Principal Investigator
  • Clinical Study of STI Screening to Prevent Adverse Birth and Newborn Outcomes
    NIH · R01AI149339 · Jan 7, 2020 – Dec 31, 2024 · Role: Principal Investigator
  • Syphilis Immunology and Biology to Improve Clinical Management and Vaccine Design
    NIH · R01AI139265 · Sep 1, 2018 – Oct 31, 2028 · Role: Principal Investigator
  • Reducing excess broad-spectrum antibiotic use in gonorrhea
    NIH · R21AI117256 · Apr 19, 2016 – Mar 31, 2019 · Role: Principal Investigator
  • Pilot Study of STI Screening and Treatment for PMTCT
    NIH · R21HD084274 · Sep 23, 2015 – Jul 31, 2018 · Role: Principal Investigator
  • Controlling Drug Resistant Gonorrhea with Real-Time PCR Susceptibility Testing
    NIH · R21AI109005 · Aug 15, 2014 – Jan 31, 2017 · Role: Principal Investigator

Publications

  • Maternal and congenital syphilis at a national referral center in Peru, 2023-2025. Int J STD AIDS. 2026 Sep 17; 9564624261487375.. View in PubMed
  • Clinician-observed genital lesions among pregnant women in a high HIV/sexually transmitted infection prevalence setting. Int J STD AIDS. 2026 Sep 09; 9564624261487933.. View in PubMed
  • Maternal Syphilis of Unknown Duration: Birth Outcomes in an Immediate Test-and-Treat Cohort often Receiving Fewer than Three Doses of Benzathine Penicillin G. Sex Transm Dis. 2026 Aug 21.. View in PubMed
  • Awareness of Hepatitis C Test Results Among Reported Cases in Los Angeles County, 2021-2022. Public Health Rep. 2026 Aug 17; 333549261477059.. View in PubMed
  • Mycoplasma genitalium infection and adverse pregnancy outcomes among pregnant women in South Africa: prospective cohort study. medRxiv. 2026 Aug 11.. View in PubMed
  • Cost-effectiveness and cost-utility of antenatal sexually transmitted infection screening to reduce preterm birth and low birthweight in South Africa. medRxiv. 2026 Aug 10.. View in PubMed
  • An Exploratory Study of Host Plasma Proteomic Signatures that Distinguish Secondary and Early Latent Syphilis in Adults. Open Forum Infect Dis. 2026 Aug; 13(8):ofag498.. View in PubMed
  • Beyond Ceftriaxone: The Future of Gonorrhea Diagnosis and Treatment. Clin Infect Dis. 2026 Jul 23; 83(1):21-24.. View in PubMed
  • Discrepancy Between Active Trachoma and Tests of Chlamydial Infection in Alto Amazonas, Peru. Clin Infect Dis. 2026 Jul 23; 83(1):131-138.. View in PubMed
  • A New Choice for Doxycycline Prophylaxis. Clin Infect Dis. 2026 Jul 08; 82(6):1063-1064.. View in PubMed