Jesse Lee Berry, MD

Professor of Ophthalmology, Dermatology, Radiation Oncology and Cancer Biology (Clinical Scholar)

Lucy and Berle Adams Chair in Cancer Research

Division Chief, Ocular Oncology Service

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Overview

Jesse L. Berry, MD is Professor Ophthalmology, Director of Ocular Oncology and Chief of Ophthalmology at Children’s Hospital Los Angeles (CHLA) and the University of Southern California (USC) Roski Eye Institute. She received her undergraduate and medical degree from Harvard University followed by ophthalmology and fellowship training at CHLA+USC under the mentorship of A. Linn Murphree, MD. Dr. Berry is the founder of Women in Ocular Oncology, President of the International Society of Ocular Oncology (ISOO, 2024-26) and treasurer of the American Association for Ophthalmic Oncology and Pathology (AAOOP, 2023-2025). Her clinical expertise focuses on retinoblastoma and uveal melanoma. She holds the A. Linn Murphree, MD Chair in Retinoblastoma and the Berle and Lucy Adams Chair in Cancer Research. She has pioneered development of the aqueous humor as a liquid biopsy for retinoblastoma and other ocular tumors; this research is supported by the National Cancer Institute.

Awards

  • 2000
     -: Harvard College Scholarship: Elizabeth Cary Agassiz Scholar, 2000
     – 2004
  • 2000
     -: Malcolm Kinsberg Scholarship, 2000
     – 2004
  • Kappa Alpha Theta Foundation Scholarship, 2002
  • David Rockefeller Center of Latin American Studies Grant, 2003
  • 2004
     -: Nevil & Louise Ford Scholarship Fund, 2004
     – 2008
  • Harvard Medical International Initiatives in Research Grant, 2005
  • Center for Eye Research and Education McCleary Grant, 2007
  • Doheny Eye Institute Medical Knowledge Award, 2011
  • Starr Schulman Fellowship, 2012
  • Department of Health Services Innovation Grant, 2012
  • Society of Heed Fellows, 2013
  • 2013
     -: University of Southern California Excellence in Resident Teaching Award, 2013
     – 2014

Education and Training

  • Harvard University — BA — 2004
  • Harvard Medical School — MD — 2008
  • USC Roski Eye Institute — Ophthalmology Residency — 2012
  • Children's Hospital Los Angeles — Ocular Oncology Fellowship — 2014

Research Funding

  • Validation of an aqueous humor liquid biopsy for molecular prognostication and monitoring of children with retinoblastoma.
    NIH · R01CA282759 · Aug 1, 2023 – Jul 31, 2028 · Role: Principal Investigator
  • Development of a surrogate liquid biopsy from the aqueous humor in retinoblastoma eyes.
    NIH · K08CA232344 · Aug 1, 2018 – Jul 31, 2023 · Role: Principal Investigator

Publications

  • Development of Poliosis in Patients Treated With Immunotherapy for Metastatic Cutaneous and Non-Cutaneous Melanoma. Pigment Cell Melanoma Res. 2026 May; 39(3):e70089.. View in PubMed
  • Modeled Aqueous Humor Protein Concentrations to Enable Biomarker Development in Uveal Melanoma. Int J Mol Sci. 2026 Mar 30; 27(7).. View in PubMed
  • Saving the Eye, Counting the Cost: Rethinking Treatment Burden in Unilateral Retinoblastoma. Clin Exp Ophthalmol. 2026 Mar; 54(2):183-185.. View in PubMed
  • Cognition and Anesthesia Exposure in Adolescent and Young Adult Retinoblastoma Survivors. Paediatr Anaesth. 2026 May; 36(5):549-559.. View in PubMed
  • Prospective implementation of an aqueous humor liquid biopsy platform informs clinical diagnosis and management of retinoblastoma and other intraocular lesions. NPJ Precis Oncol. 2026 Jan 12; 10(1):53.. View in PubMed
  • Adjuvant Chemotherapy in Retinoblastoma with Postlaminar Optic Nerve Invasion: A Global Multicenter Study. Ophthalmol Retina. 2026 May; 10(5):562-572.. View in PubMed
  • Diffuse infiltrating retinoblastoma: a multicentre, international, data-sharing study. Br J Ophthalmol. 2025 Nov 20; 109(12):1409-1416.. View in PubMed
  • Aqueous Humor Liquid Biopsy Identifies Murine Double Minute 4 Segmental Gain in Retinoblastoma: Implications for Chemotherapy Response and Precision Oncology. JCO Precis Oncol. 2025 Aug; 9:e2500250.. View in PubMed
  • The use of aqueous humor cfDNA for low-pass whole genome sequencing as a clinical test to identify intraocular retinoblastoma recurrence. ScienceBank. 2025; 2025.. View in PubMed
  • Clinical Stage of Retinoblastoma Based on Presenting Signs of 4578 Patients from 121 Countries. Ophthalmology. 2025 09; 132(9):1045-1053.. View in PubMed