Evaluation of the aqueous humor for tumor-derived genetic information and its application to prognosis and precision medicine for retinoblastoma patients. Investigating new methods of chemotherapy delivery for the treatment of Retinoblastoma. Evaluating treatment outcomes for Retinoblastoma eyes. This includes evaluation of treatment outcomes after systemic chemotherapy and the elucidation of factors present at diagnosis, which contribute to final visual outcome in eyes treated for retinoblastoma.
: University of Southern California Excellence in Resident Teaching Award, 2013-2014
: Society of Heed Fellows, 2013
: Department of Health Services Innovation Grant, 2012
: Starr Schulman Fellowship, 2012
: Doheny Eye Institute Medical Knowledge Award, 2011
: Center for Eye Research and Education McCleary Grant, 2007
: Harvard Medical International Initiatives in Research Grant, 2005
: Nevil & Louise Ford Scholarship Fund, 2004-2008
: David Rockefeller Center of Latin American Studies Grant, 2003
: Kappa Alpha Theta Foundation Scholarship, 2002
: Malcolm Kinsberg Scholarship, 2000-2004
: Harvard College Scholarship: Elizabeth Cary Agassiz Scholar, 2000-2004
Aqueous Humor Is Superior to Blood as a Liquid Biopsy for Retinoblastoma Ophthalmology. 2019 Oct 31. . View in PubMed
Metastases and death rates after primary enucleation of unilateral retinoblastoma in the USA 2007-2017 Br J Ophthalmol. 2019 Sep; 103(9):1272-1277. . View in PubMed
Tumour size criteria for Group D and E eyes in the International Classification System for Retinoblastoma: effects on rates of globe salvage and high-risk histopathologic features Acta Ophthalmol. 2019 Aug 17. . View in PubMed
Posterior Vitreous Detachment and the Associated Risk of Retinal Toxicity with Intravitreal Melphalan Treatment for Retinoblastoma Ocul Oncol Pathol. 2019 Jun; 5(4):238-244. . View in PubMed
Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System JAMA Intern Med. 2019 May 01; 179(5):648-657. . View in PubMed
Aqueous Humor Markers in Retinoblastoma, a Review Transl Vis Sci Technol. 2019 Apr; 8(2):13. . View in PubMed
Extending far and wide: the role of biopsy and staging in the management of ocular surface squamous neoplasia Clin Exp Ophthalmol. 2019 03; 47(2):193-200. . View in PubMed
Changes in Retinal Thickness on OCT from Intravitreal Melphalan Ophthalmol Retina. 2019 03; 3(3):288-289. . View in PubMed
Trends in Radiation Practices for Female Ocular Oncologists in North America: A Collaborative Study of the International Society of Ocular Oncology Ocul Oncol Pathol. 2019 Jan; 5(1):54-59. . View in PubMed
Next-Generation Technologies and Strategies for the Management of Retinoblastoma Genes (Basel). 2019 12 11; 10(12). . View in PubMed
The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene Genes (Basel). 2019 11 01; 10(11). . View in PubMed
Lens Dose-Response Prediction Modeling and Cataract Incidence in Patients With Retinoblastoma After Lens-Sparing or Whole-Eye Radiation Therapy Int J Radiat Oncol Biol Phys. 2019 04 01; 103(5):1143-1150. . View in PubMed
A Review of Recurrent Retinoblastoma: Children's Hospital Los Angeles Classification and Treatment Guidelines Int Ophthalmol Clin. 2019; 59(2):65-75. . View in PubMed
An Intraocular Pressure Predictive of High-risk Histopathologic Features in Group E Retinoblastoma Eyes Int Ophthalmol Clin. 2019; 59(2):77-86. . View in PubMed
Porous orbital implant after enucleation in retinoblastoma patients: indications and complications Orbit. 2018 Dec; 37(6):438-443. . View in PubMed
Integrated Treatment during the Intravitreal Melphalan Era: Concurrent Intravitreal Melphalan and Systemic Chemoreduction Ocul Oncol Pathol. 2018 Nov; 4(6):335-340. . View in PubMed
Outcomes of choroidal melanomas treated with eye physics plaques: A 25-year review Brachytherapy. 2018 Nov - Dec; 17(6):981-989. . View in PubMed
Conjunctival Squamous Neoplasia: Staging and Initial Treatment Cornea. 2018 Oct; 37(10):1287-1291. . View in PubMed
Atypical Retinal Pigment Epithelial Hyperplasia and Glial Proliferation Masquerading as Progressive Recurrent Retinoblastoma: A Case Report Review and Clinicopathologic Correlation Ocul Oncol Pathol. 2018 Sep; 4(2):116-121. . View in PubMed
Late Apical Recurrence of Choroidal Melanoma 10 Years after Successful Treatment with Brachytherapy Ocul Oncol Pathol. 2018 Jun; 4(4):225-229. . View in PubMed
Iris Hypoplasia as the Presenting Sign of Retinoblastoma in a Child With a 13q Deletion J Pediatr Ophthalmol Strabismus. 2018 Apr 23; 55:e10-e13. . View in PubMed
Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma Mol Cancer Res. 2018 11; 16(11):1701-1712. . View in PubMed
Lurking below: massive choroidal invasion under a calcified tumor after attempted conservative therapy for retinoblastoma Ophthalmic Genet. 2018 10; 39(5):653-657. . View in PubMed
Lack of correlation between age at diagnosis and RB1 mutations for unilateral retinoblastoma: the importance of genetic testing Ophthalmic Genet. 2018 06; 39(3):407-409. . View in PubMed
Loss of fundus view as an indication for secondary enucleation in retinoblastoma Pediatr Blood Cancer. 2018 04; 65(4). . View in PubMed
Three presentations of CNS disease in patients with intraocular retinoblastoma at a tertiary medical center in the United States Ophthalmic Genet. 2018 Jan-Feb; 39(1):115-119. . View in PubMed
Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma-Reply JAMA Ophthalmol. 2018 05 01; 136(5):598. . View in PubMed
Rabbit model of ocular indirect photodynamic therapy using a retinoblastoma xenograft Graefes Arch Clin Exp Ophthalmol. 2017 Dec; 255(12):2363-2373. . View in PubMed
Long-term outcomes of Group D retinoblastoma eyes during the intravitreal melphalan era Pediatr Blood Cancer. 2017 Dec; 64(12). . View in PubMed
Unilateral Multifocal Choroidal Melanoma Ocul Oncol Pathol. 2017 Dec; 4(1):48-51. . View in PubMed
Optic Nerve Obscuration in Retinoblastoma: A Risk Factor for Optic Nerve Invasion? Ocul Oncol Pathol. 2017 Nov; 3(4):283-291.. View in PubMed
Clinical Significance of Optic Nerve Enhancement on Magnetic Resonance Imaging in Enucleated Retinoblastoma Patients Ophthalmol Retina. 2017 Sep - Oct; 1(5):369-374. . View in PubMed
Treatment Outcomes of Focal Laser Consolidation during Chemoreduction for Group B Retinoblastoma Ophthalmol Retina. 2017 Sep - Oct; 1(5):361-368. . View in PubMed
Acute Lymphoblastic Leukemia Relapse Presenting as Optic Nerve Infiltration JAMA Ophthalmol. 2017 Jan 12; 135(1):e164656. . View in PubMed
Not All Seeds Are Created Equal: Seed Classification Is Predictive of Outcomes in Retinoblastoma Ophthalmology. 2017 12; 124(12):1817-1825. . View in PubMed
Optical Coherence Tomography Imaging of a Large Spherical Seed in Retinoblastoma Ophthalmology. 2017 08; 124(8):1208. . View in PubMed
Risk of metastasis and orbital recurrence in advanced retinoblastoma eyes treated with systemic chemoreduction versus primary enucleation Pediatr Blood Cancer. 2017 04; 64(4). . View in PubMed
Risk of Extraocular Extension in Eyes With Retinoblastoma Receiving Intravitreous Chemotherapy JAMA Ophthalmol. 2017 12 01; 135(12):1426-1429. . View in PubMed
Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma JAMA Ophthalmol. 2017 11 01; 135(11):1221-1230. . View in PubMed
Acute Hemorrhagic Retinopathy following Intravitreal Melphalan Injection for Retinoblastoma: A Report of Two Cases and Technical Modifications to Enhance the Prevention of Retinal Toxicity Ocul Oncol Pathol. 2017 Jan; 3(1):34-40. . View in PubMed
Detection and Intraretinal Localization of an 'Invisible' Retinoblastoma Using Optical Coherence Tomography Ocul Oncol Pathol. 2016 Apr; 2(3):148-52. . View in PubMed
Patterns of subretinal fluid resolution in Group D eyes treated with chemoreduction: Experience from the Children's Hospital Los Angeles/University of Southern California Ophthalmic Genet. 2016 12; 37(4):400-403. . View in PubMed
Long-Term Outcomes of Group B Eyes in Patients with Retinoblastoma Treated with Short-Course Chemoreduction: Experience from Children's Hospital Los Angeles/University of Southern California Ocul Oncol Pathol. 2015 Dec; 2(2):105-11. . View in PubMed
Orbital Recurrence following Aggressive Laser Treatment for Recurrent Retinoblastoma Ocul Oncol Pathol. 2015 Dec; 2(2):76-9. . View in PubMed
Outcomes of medium choroidal melanomas treated with ruthenium brachytherapy guided by three-dimensional pretreatment modeling Brachytherapy. 2015 Sep-Oct; 14(5):718-25. . View in PubMed
Use of the Toric Surgical Marker to Aid in Intraoperative Plaque Placement for the USC Eye Physics Plaques to Treat Uveal Melanoma: A New Surgical Technique Ophthalmic Surg Lasers Imaging Retina. 2015 Sep; 46(8):866-70. . View in PubMed
Low-Dose Chemoreduction for Infants Diagnosed with Retinoblastoma before 6 Months of Age Ocul Oncol Pathol. 2015 Feb; 1(2):103-10. . View in PubMed
Methicillin-resistant Staphylococcus aureus dacryoadenitis JAMA Ophthalmol. 2014 Aug; 132(8):993-5. . View in PubMed
Factors predictive of long-term visual outcomes of Group D eyes treated with chemoreduction and low-dose IMRT salvage: the Children's Hospital Los Angeles experience Br J Ophthalmol. 2014 Aug; 98(8):1061-5. . View in PubMed
Outcomes of choroidal melanomas treated with eye physics: a 20-year review JAMA Ophthalmol. 2013 Nov; 131(11):1435-42. . View in PubMed
Long-term outcomes of Group D eyes in bilateral retinoblastoma patients treated with chemoreduction and low-dose IMRT salvage Pediatr Blood Cancer. 2013 Apr; 60(4):688-93. . View in PubMed
Unmet need for corrective eyeglasses: results from a Los Angeles County Hospital survey Int Ophthalmol. 2012 Jun; 32(3):245-50. . View in PubMed
Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3868-73. . View in PubMed
Effect of saline conditions on the tensile strength of ophthalmic sutures Ophthalmic Surg Lasers Imaging. 2011 Mar-Apr; 42(2):148-51. . View in PubMed
Histopathologic findings of eyes enucleated after treatment with chemosurgery for retinoblastoma Open Ophthalmol J. 2011 Jan 18; 5:1-5. . View in PubMed
