Jessica Tsai

Assistant Professor of Pediatrics and Cancer Biology

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Education and Training

  • Stanford University, Stanford, CA — B.S. — 06/2008 — Biological Sciences, Honors in Neurobiology
  • Stanford University School of Medicine, Stanford, CA — M.D. — 06/2015 — Medicine
  • Stanford University School of Medicine, Stanford, CA — Ph.D. — 06/2015 — Neurosciences
  • Boston Children's Hospital | Boston Medical Center, Boston, MA — 07/2018 — Pediatrics Residency
  • Dana-Farber Cancer Institute, Boston, MA — 07/2021 — Pediatric Hematology-Oncology Fellowship

Publications

  • A human stem cell model of neuroblastoma identifies four chromosome 17q genes that drive tumor initiation and progression. Cancer Lett. 2026 Aug 26; 660:218781.. View in PubMed
  • Quantum mechanics-based multitensor AI/ML uniquely able to discover, validate, and interpret predictors from small-cohort noisy high-dimensional multiomic data. APL Quantum. 2026 Jun; 3(2):026116.. View in PubMed
  • Combined somatic mutation and transcriptome analysis reveals region-specific differences in clonal architecture in human cortex. Cell Rep. 2025 11 25; 44(11):116458.. View in PubMed
  • Maximizing grant funding: strategies for negotiating laboratory pricing. Trends Biochem Sci. 2025 04; 50(4):281-284.. View in PubMed
  • Inclusive mentorship of pediatric trainees: pediatric oncology as a microcosm. Front Oncol. 2025; 15:1531784.. View in PubMed
  • Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex. bioRxiv. 2023 Nov 06.. View in PubMed
  • BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma. Neuro Oncol. 2023 04 06; 25(4):735-747.. View in PubMed
  • Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma. Neuro Oncol. 2022 11 02; 24(11):1964-1975.. View in PubMed
  • FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits. Cancer Res. 2022 09 02; 82(17):2980-3001.. View in PubMed
  • Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity. Nat Aging. 2022 08; 2(8):714-725.. View in PubMed