Keck School Faculty

mTOR inhibition suppresses Myc-driven polyposis by inducing immunogenic cell death Oncogene. 2023 May 03. . View in PubMed

Targeting Myc-driven stress addiction in colorectal cancer Drug Resist Updat. 2023 Apr 20; 69:100963. . View in PubMed

Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer Mol Biomed. 2022 Mar 21; 3(1):10. . View in PubMed

Interferon b drives intestinal regeneration after radiation Sci Adv. 2021 Oct 08; 7(41):eabi5253. . View in PubMed

eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis Elife. 2020 Nov 02; 9. . View in PubMed

MLH1 Deficiency Induces Cetuximab Resistance in Colon Cancer via Her-2/PI3K/AKT Signaling Adv Sci (Weinh). 2020 Jul; 7(13):2000112. . View in PubMed

Targeting p53-dependent stem cell loss for intestinal chemoprotection Sci Transl Med. 2018 Feb 07; 10(427). . View in PubMed

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice J Clin Invest. 2016 Nov 01; 126(11):4076-4087. . View in PubMed

mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation Oncogene. 2016 Jan 14; 35(2):148-57. . View in PubMed

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome Cell Stem Cell. 2008 Jun 05; 2(6):576-83. . View in PubMed

PUMA mediates the apoptotic response to p53 in colorectal cancer cells Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1931-6. . View in PubMed

PUMA induces the rapid apoptosis of colorectal cancer cells Mol Cell. 2001 Mar; 7(3):673-82. . View in PubMed