Jin Piao, PhD

Associate Professor of Clinical Population and Public Health Sciences

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Dr. Jin Piao is an Associate Professor from the Division of Biostatistics, Department of Population and Public Health Sciences, the University of Southern California. She has been working on the development of methodological approaches that have direct impacts on biomedical applications. Her research interest lies in the areas including clinical trial design and analysis, survival analysis, semiparametric statistical models, and meta-analysis. In addition to statistical methodological research, she has been actively collaborated with physicians and biologists in pediatric solid tumors areas and supported several phases I, II, or III solid tumors clinical trials at Children’s Oncology Group.


  • A multi-institutional feasibility study of intra-arterial chemotherapy in children with retinoblastomaA Children’s Oncology Group study (COG ARET12P1). Pediatr Blood Cancer. 2024 Jan; 71(1):e30718. . View in PubMed
  • Rare Tumors: Opportunities and challenges from the Children’s Oncology Group perspective EJC Paediatr Oncol. 2023 Dec; 2. . View in PubMed
  • Refining the serum miR-371a-3p test for viable germ cell tumor detection: identification and definition of an indeterminate range Res Sq. 2023 Mar 21. . View in PubMed
  • Children’s Oncology Group’s 2023 blueprint for research: Rare tumors Pediatr Blood Cancer. 2023 09; 70 Suppl 6:e30574. . View in PubMed
  • Vincristine/irinotecan/temsirolimus upfront window treatment of high-risk hepatoblastoma: A report from the Children’s Oncology Group AHEP0731 Study Committee Pediatr Blood Cancer. 2023 07; 70(7):e30365. . View in PubMed
  • Tazemetostat for tumors harboring SMARCB1/SMARCA4 or EZH2 alterations: results from NCI-COG pediatric MATCH APEC1621C J Natl Cancer Inst. 2023 11 08; 115(11):1355-1363. . View in PubMed
  • Refining the serum miR-371a-3p test for viable germ cell tumor detection Sci Rep. 2023 06 29; 13(1):10558. . View in PubMed
  • Outcomes of children with well-differentiated fetal hepatoblastoma treated with surgery only: Report from Children’s Oncology Group Trial, AHEP0731 J Pediatr Surg. 2022 Oct; 57(10):251-256. . View in PubMed
  • EMBRACE: An EM-based bias reduction approach through Copas-model estimation for quantifying the evidence of selective publishing in network meta-analysis Biometrics. 2022 06; 78(2):754-765. . View in PubMed
  • Small Cell Undifferentiated Histology Does Not Adversely Affect Outcome in Hepatoblastoma: A Report From the Children’s Oncology Group (COG) AHEP0731 Study Committee J Clin Oncol. 2022 02 10; 40(5):459-467. . View in PubMed
  • Intensive Multimodality Therapy for Extraocular Retinoblastoma: A Children’s Oncology Group Trial (ARET0321) J Clin Oncol. 2022 11 20; 40(33):3839-3847. . View in PubMed
  • Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children’s Oncology Group Pediatric MATCH Trial J Clin Oncol. 2022 07 10; 40(20):2224-2234. . View in PubMed
  • Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial J Clin Oncol. 2022 07 10; 40(20):2235-2245. . View in PubMed
  • Doxorubicin in combination with cisplatin, 5-flourouracil, and vincristine is feasible and effective in unresectable hepatoblastoma: A Children’s Oncology Group study Cancer. 2022 03 01; 128(5):1057-1065. . View in PubMed
  • Semiparametric isotonic regression modelling and estimation for group testing data Can J Stat. 2021 Sep; 49(3):659-677. . View in PubMed
  • Imaging Appearance of Nongerminoma Pediatric Ovarian Germ Cell Tumors Does Not Discriminate Benign from Malignant Histology J Pediatr Adolesc Gynecol. 2021 Jun; 34(3):383-386. . View in PubMed
  • A Multi-institutional Pooled Analysis Demonstrates That Circulating miR-371a-3p Alone is Sufficient for Testicular Malignant Germ Cell Tumor Diagnosis Clin Genitourin Cancer. 2021 12; 19(6):469-479. . View in PubMed
  • Evaluation of the diagnostic biopsy approach for children with hepatoblastoma: A report from the children’s oncology group AHEP 0731 liver tumor committee J Pediatr Surg. 2020 Apr; 55(4):655-659. . View in PubMed
  • A single-arm study of systemic and sub-Tenon chemotherapy for Groups C and D intraocular retinoblastoma: A Children’s Oncology Group study (ARET 0231) Pediatr Blood Cancer. 2020 09; 67(9):e28502. . View in PubMed
  • The importance of age as prognostic factor for the outcome of patients with hepatoblastoma: Analysis from the Children’s Hepatic tumors International Collaboration (CHIC) database Pediatr Blood Cancer. 2020 08; 67(8):e28350. . View in PubMed
  • Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features Mod Pathol. 2020 03; 33(3):496-513. . View in PubMed
  • Response adaptive randomization procedures in seamless phase II/III clinical trials J Biopharm Stat. 2020; 30(1):3-17. . View in PubMed
  • Copas-like selection model to correct publication bias in systematic review of diagnostic test studies Stat Methods Med Res. 2019 Oct-Nov; 28(10-11):2912-2923. . View in PubMed
  • Semiparametric Model for Bivariate Survival Data Subject to Biased Sampling J R Stat Soc Series B Stat Methodol. 2019 Apr; 81(2):409-429. . View in PubMed
  • Trial Design Challenges and Approaches for Precision Oncology in Rare Tumors: Experiences of the Children’s Oncology Group JCO Precis Oncol. 2019; 3. . View in PubMed
  • Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy: A Children’s Oncology Group Study J Clin Oncol. 2019 11 01; 37(31):2883-2891. . View in PubMed
  • Efficient two-stage designs and proper inference for animal studies Stat Biosci. 2018 Apr; 10(1):217-232. . View in PubMed
  • Genetic heterogeneity of uncharacterized childhood autoimmune diseases with lymphoproliferation Pediatr Blood Cancer. 2018 Feb; 65(2). . View in PubMed
  • Prognosis of patients with intermediate risk IPSS-R myelodysplastic syndrome indicates variable outcomes and need for models beyond IPSS-R Am J Hematol. 2018 10; 93(10):1245-1253. . View in PubMed
  • Semiparametric model and inference for spontaneous abortion data with a cured proportion and biased sampling Biostatistics. 2018 01 01; 19(1):54-70. . View in PubMed
  • Estimating the ratio of multivariate recurrent event rates with application to a blood transfusion study Stat Methods Med Res. 2017 Aug; 26(4):1969-1981. . View in PubMed
  • Maximum likelihood estimation and EM algorithm of Copas-like selection model for publication bias correction Biostatistics. 2017 Jul 01; 18(3):495-504. . View in PubMed
  • Tumor Thickness and Mitotic Rate Robustly Predict Melanoma-Specific Survival in Patients with Primary Vulvar Melanoma: A Retrospective Review of 100 Cases Clin Cancer Res. 2017 04 15; 23(8):2093-2104. . View in PubMed
  • A joint latent class analysis for adjusting survival bias with application to a trauma transfusion study Stat Med. 2016 Jan 15; 35(1):65-77. . View in PubMed
  • B7-H4 expression in ovarian serous carcinoma: a study of 306 cases Hum Pathol. 2016 11; 57:1-6. . View in PubMed
  • Recurrent event frailty models reduced time-varying and other biases in evaluating transfusion protocols for traumatic hemorrhageJ Clin Epidemiol. 2016 09; 77:52-59. e1. . View in PubMed
  • A joint latent class model for classifying severely hemorrhaging trauma patients BMC Res Notes. 2015 Oct 24; 8:602. . View in PubMed