John C. Lipham, MD

Professor of Clinical Surgery

Division Chief of Upper GI and General Surgery

Director, Foregut Cancer Program

Chief of USC Affiliated Academic Programs at Hoag Memorial Hospital

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Overview

John C. Lipham, M.D. is Chief of the Division of Upper GI and General Surgery and Associate Professor of Surgery at the Keck School of Medicine of USC. Dr. Lipham also served as the Foregut Cancer Program Director and Chief of USC Affiliated Academic Programs at Hoag. He was instrumental in establishing the Hoag-USC Surgical Center for Digestive Diseases. He focuses on benign and malignant diseases of the esophagus and stomach. His clinical interests include the diagnosis and treatment of GERD, hiatal hernias, Barrett’s esophagus, esophageal motility disorders, achalasia, malignant diseases of the esophagus and stomach, and gastroparesis. His current research interests include developing minimally invasive methods of diagnosing and treating gastroesophageal reflux disease, Barrett’s, esophageal cancer and gastric cancer.

Publications

  • Achieving physiologic distensibility targets frequently requires modification of standard cruroplasty during anti-reflux surgery. Surg Endosc. 2026 Sep 28.. View in PubMed
  • Blown-out myotomy: one radiographic phenotype, multiple biologic pathways. J Gastrointest Surg. 2026 Sep 10; 30(11):102590.. View in PubMed
  • Development and Reliability of a Competency Assessment Tool for Magnetic Sphincter Augmentation of the Esophagus (MSA CAT) as Part of a Video-based Surgical Quality Assurance Program for the GOLF Trial. Ann Surg. 2026 Aug 06.. View in PubMed
  • Redefining success after antireflux surgery: from acid control to mucosal recovery. J Gastrointest Surg. 2026 Jul 22; 30(10):102528.. View in PubMed
  • Esophageal Reflux Barrier Might be More than Just An Anatomical Definition: A Systematic Literature Review. J Laparoendosc Adv Surg Tech A. 2026 Jun 11; 10926429261458598.. View in PubMed
  • Safety outcomes in 602 GERD patients treated by RefluxStop: a multi-center real-world study from 22 centers across six European countries. Sci Rep. 2026 Apr 18; 16(1).. View in PubMed
  • The Tissue Systems Pathology Test Predicts Risk of Progression in Patients With Barrett’s Esophagus: Systematic Review and Meta-Analysis. J Clin Gastroenterol. 2026 Apr 01; 60(4):299-308.. View in PubMed
  • The location and degree of residual disease determines recurrence patterns and survival in patients with esophageal adenocarcinoma after trimodal therapy. Dis Esophagus. 2025 Nov 01; 38(6).. View in PubMed
  • National Trends in Emergent Paraesophageal Hernia Repair Over 8 Years. Am Surg. 2026 Jan; 92(1):7-14.. View in PubMed
  • Why the BOSS Trial Falls Short of Guiding Clinical Practice in Barrett’s Esophagus. Ann Surg. 2026 Apr 01; 283(4):562-563.. View in PubMed